ACR Meeting Abstracts

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  • Abstract Number: 0444 • ACR Convergence 2024

    Deep Serologic Profiling Identifies Novel Autoantibodies Associated with Fetal Atrioventricular Block

    Philip Carlucci1, Robert Clancy2, Mala Masson3, Colin Phoon4, Ashley Roman4, Peter Izmirly5, Amit Saxena6, H Michael Belmont4, Christina Penfield4, Young Mi Lee4, Julie Nusbaum7, Andrew Rubenstein4, Ruben Acherman8, Elena Sinkovskaya9, Alfred Abuhamad9, Karla Bermudez-Wagner9, Majd Makhoul10, Gary Satou11, Whitnee Hogan12, Nelangi Pinto13, Anita Moon-Grady14, Lisa Howley15, Mary Donofrio16, Anita Krishnan16, Jaclyn Phillips17, Stephanie Levasseur18, Miwa Geiger19, Erin Paul20, Sonal Owens21, Kristopher Cumbermack22, Jyothi Matta23, Gary Joffe24, Christopher Lindblade25, Carl Weiner26, Caitlin Haxel27, Katherine Kohari28, Joshua Copel28, James Strainic29, Tam Doan30, Shreya Sheth30, Stacy Killen31, Theresa Tacy32, Michelle Kaplinski32, Nicola Fraser4, Kelly Ruggles33, Bettina Cuneo34 and Jill Buyon35, 1New York University School of Medicine, New York, NY, 2Columbia University Medical Center, New York, NY, 3NYU Langone Medical Center- Division of Rheumatology, New York, NY, 4NYU Langone Health, New York, NY, 5New York University Grossman School of Medicine, New York, NY, 6NYU Grossman School of Medicine, New York, NY, 7NYU Langone Hospital - Long Island, Internal Medicine - Rheumatology, Mineola, NY, 8Children's Heart Center, Las Vegas, NV, 9Eastern Virginia Medical School, Norfolk, VA, 10Atrium Health Levine Children's Hospital, Charlotte, NC, 11University of California Los Angeles, Los Angeles, CA, 12University of Utah, Salt Lake City, UT, 13Seattle Children's Hospital, Seattle, WA, 14University of California San Francisco, San Francisco, CA, 15Midwest Fetal Care Center, Children's Minnesota/Allina Health, Minneapolis, MN, 16Children's National Hospital, Washington, DC, 17George Washington University, Washington, DC, 18Columbia University, New York, NY, 19Mount Sinai School of Medicine, New York, NY, 20Atlantic Health System, Morristown, NJ, 21University of Michigan, Ann Arbor, MI, 22University of Kentucky, Lexington, KY, 23University of Louisville, Louisville, KY, 24Perinatal Associates of New Mexico, Albuquerque, NM, 25Phoenix Children's Hospital, Phoenix, AZ, 26Dignity Health, Phoenix, AZ, 27University of Vermont Children's Hospital, Burlington, VT, 28Yale University, New Haven, CT, 29UH Rainbow Babies, Cleveland, OH, 30Baylor College of Medicine, Houston, TX, 31Vanderbilt University, Nashville, TN, 32Stanford University, Stanford, CA, 33NYU Grossman School of Medicine, Brooklyn, NY, 34University of Arizona College of Medicine, Tucson, AZ, 35New York University Grossman School of Medicine, New York, NY

    Background/Purpose: Maternal anti-SSA/Ro52/60kD autoantibodies are necessary for the development of fetal atrioventricular block (AVB) but titers alone are not sufficient to predict the likelihood of…
  • Abstract Number: 0415 • ACR Convergence 2024

    Prevalence and Risk Factors of Low Bone Mineral Density in Children with Juvenile Idiopathic Arthritis

    narendra bagri, Sushain Kalsotra, vandana jain, Manisha Jana, Maroof Ahmed Khan, Yashdeep Gupta and Sumit Kumar Das, All India Institute of Medical Sciences, New Delhi, Delhi, India

    Background/Purpose: Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatological disease in children less than 16 years of age. Various factors have been suggested…
  • Abstract Number: 0261 • ACR Convergence 2024

    Clinical Implications, Bacterial Profiles, and Patient Outcomes in Hospitalized Patients with Autoimmune Rheumatic Diseases

    Angel Kevin Garza-Elizondo1, Ana Cecilia Bardan-Inchaustegui2, Pablo Gamez-Siller3, Diana Elsa Flores-Alvarado4, Jorge Esquivel-Valerio5, Jesus Cardenas-de la Garza2, Elsa Catalina Davila-Correa6, Alejandra Jacquelin Osuna-Corrales6, Karla Judith Duran-Villarreal6, Daniela Alejandra Salcedo-Soto7, Derek de Jesus Gauna-Leal6, Andrea Axelle Prado-Prado6, Debanhi Morales-Espronceda6, Nathalia Valdez-Benavides6, Nirvana Amairany González-Ontiveros6 and Dionicio Galarza-Delgado8, 1Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, San Nicolás de los Garza, Mexico, 2Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico, 3Facultad de Medicina UANL, Monterrey, Nuevo León, Mexico, 4Hospital Universitario Jose Eleuterio Gonzalez, Monterrey, Nuevo León, Mexico, 5Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, MONTERREY, Mexico, 6Hospital Universitario "Dr. Jose Eleuterio Gonzalez", Monterrey, Mexico, 7Hospital Universitario Dr Jose Eleuterio Gonzalez, Monterrey, Mexico, 8UANL Hospital Universitario, Monterrey, Nuevo León, Mexico

    Background/Purpose: Autoimmune rheumatic diseases (ARD) are chronic conditions that affect multiple organ systems. Patients with ARD tend to have a weak immune system due to…
  • Abstract Number: 0468 • ACR Convergence 2024

    Plasma Calprotectin Assessed in Multiple Biological Treatment Strategies for Early Rheumatoid Arthritis over 48 Weeks

    David Stevens1, Lene Sundbakk2, Amirhossein Kazemi2, Marte Heiberg3, Tuulikki Sokka-Isler4, Bjorn Gudbjornsson5, Kristina Lend6, Anna Rudin7, Michael Nurmohamed8, Jon Lampa9, Merete Hetland10, Mikkel Ostergaard11, Ronald Van Vollenhoven12, Tillmann Uhlig2, Espen Haavardsholm2 and Hilde Hammer3, 1St. Olavs hospital, Trondheim, Norway, 2Diakonhjemmet Hospital, Oslo, Norway, 3Diakonhjemmet Hospital, Oslo, Oslo, Norway, 4University of Eastern Finland, Faculty of Health Sciences, Jyvaskyla, Finland, 5Landspitali University Hospital and University of Iceland, Reykjavik, Iceland, 6Amsterdam UMC, Karolinska Institute, Stockholm, Sweden, 7Institute of Medicine, University of Gothenburg, Gothenburg, Sweden, 8Amsterdam University Medical Centers, Amsterdam, Netherlands, 9Karolinska University Hospital, Hässelby, Sweden, 10Rigshospitalet Glostrup and University of Copenhagen, Glostrup, Denmark, 11Department of Clinical Medicine, University of Copenhagen and Center for Rheumatology, Copenhagen Center for Arthritis Research, Glostrup, Denmark, 12Department of Rheumatology and Clinical Immunology, Amsterdam University Medical Centers, Amsterdam, Netherlands

    Background/Purpose: Plasma calprotectin is a sensitive biomarker of inflammation in patients with rheumatoid arthritis (RA) and reflects activation of granulocytes and macrophages. Calprotectin has not…
  • Abstract Number: 0445 • ACR Convergence 2024

    Evaluating Clinical Reasoning in Randomized Surveys of Lupus Nephritis and Preeclampsia Pregnancy Case Workups: A Clinical Conundrum

    Liya Stolyar1, Sadaf Sediqi2, Richard Lafayette3, Maurice Druzin4, Saadiya Hawa5, Amanda Moyer6, Yashaar Chaichian2 and Julia Simard2, 1Palo Alto VA Medical Center/Stanford, Stanford, CA, 2Stanford School of Medicine, Stanford, CA, 3Stanford, Stanford, CA, 4Stanford University School of Medicine, Stanford, CA, 5Weiss Memorial Hospital, Chicago, IL, 6Stanford University, San Bruno, CA

    Background/Purpose: Systemic lupus erythematosus (SLE) pregnancy is associated with a heightened risk of adverse pregnancy outcomes, including preeclampsia. Distinguishing preeclampsia from lupus nephritis (LN) presents…
  • Abstract Number: 0460 • ACR Convergence 2024

    Cartilage Damage or (sub)luxation of Finger Joints: Impact on Physical Function in Patients with Rheumatoid Arthritis

    Takehisa Ogura1, Yasuto Minegishi2, Chihiro Imaizumi1, Reina Maezawa1, Takaharu Katagiri1 and Hideto Kameda1, 1Toho university, Tokyo, Japan, 2Toho University, Tokyo

    Background/Purpose: It has been reported that radiographic joint space narrowing (JSN) score affects the health assessment questionnaire-disability index (HAQ-DI) score in rheumatoid arthritis (RA) patients.…
  • Abstract Number: 0367 • ACR Convergence 2024

    Opinions from Rheumatoid Arthritis Patients and Providers on Discontinuing Methotrexate in Stable Disease

    Peri Newman1, Sharon Banks1, Rayford June2, Erik Lehman3, Glennys Smith4, Vandana Rai4, Nicole Wilson4, Nancy Olsen5 and Tarun Sharma4, 1Penn State Health, Hershey, PA, 2Penn State College of Medicine/Lebanon VA Medical Center, Hummelstown, PA, 3Penn State College of Medicine, Hershey, PA, 4Allegheny Health Network, Pittsburgh, PA, 5Penn State University/Milton S Hershey, Hershey, PA

    Background/Purpose: The 2021 American College of Rheumatology guidelines for treatment of rheumatoid arthritis (RA) conditionally recommend a gradual discontinuation of methotrexate (MTX) over biologic discontinuation.…
  • Abstract Number: 0417 • ACR Convergence 2024

    Contraception in Community Rheumatology Practices

    Megan Clowse1, Julie Chiesa2, Pamela Freeman3, Bansari Gujar4, Kelley Jones5, Richard Jones6, Ann Marslett7, Amanda Snyderman5 and Leah Zulig8, 1Duke University, Chapel Hill, NC, 2InfoDirectors, Durham, NC, 3Rheumatology Associates of Central Florida, Orlando, FL, 4Rheumatology Associates of Baltimore, Towson, MD, 5Duke University School of Medicine, Durham, 6Clinic for Rheumatic Diseases, Northport, AL, 7Rheumatology Associates of Baltimore, Baltimore, MD, 8Duke University School of Medicine, Durham, NC

    Background/Purpose: Most prior studies of contraception in women with rheumatic disease focused on academic centers. In this study of non-academic rheumatology practices, we sought to…
  • Abstract Number: 0271 • ACR Convergence 2024

    Intercritical Gout Represents a Systemic Inflammatory State

    Tanner Ourada1, Austin Wheeler2, Michael Duryee2, Bryant England2, Richard Reynolds3, James O'Dell2, Jeff Newcomb2, Michael Pillinger4, Robert Terkeltaub5, Ryan Ferguson6, Mary Brophy6, Tony Merriman7 and Ted Mikuls2, 1University of Nebraska-Medical Center: College of Medicine, Omaha, NE, 2University of Nebraska Medical Center, Omaha, NE, 3University of Alabama at Birmingham, Birmingham, AL, 4New York University Grossman School of Medicine, New York,, NY, 5Retired, San Diego, CA, 6Veterans Affairs, Boston, MA, 7University of Alabama at Birmingham, Homewood, AL

    Background/Purpose: The presence of systemic inflammation during gout flares is well characterized. While initial research suggests inflammation persists in intercritical gout, these reports have come…
  • Abstract Number: 0483 • ACR Convergence 2024

    Obesity, Prednisone Use, and Patient-Reported Outcomes Are Predictors of Becoming Difficult-to-Treat in an RA Population Treated with a First-Line Biologic DMARD

    Misti Paudel1, Shravani Chitineni1, Ruogu Li2, Chinmayi Naik3, Nancy Shadick3, Michael Weinblatt4 and Daniel Solomon5, 1Brigham and Women's Hospital, Division of Rheumatology, Inflammation, and Immunity, Boston, MA, 2Brigham and Women's Hospital, Boston, MA, 3Brigham and Women’s Hospital, Boston, MA, 4Brigham and Women's Hospital/ Harvard Medical School, Waban, MA, 5Brigham and Women's Hospital, Newton, MA

    Background/Purpose: Prior studies have evaluated the risk factors for difficult-to-treat RA (D2T-RA) but have not applied EULAR’s full criteria for D2T-RA in a longitudinal data…
  • Abstract Number: 0017 • ACR Convergence 2024

    Syndecan-1 Plays a Role in the Pathogenesis of Sjögren’s Syndrome by Inducing B-cell Chemotaxis Through CXCL13-heparan Sulfate Interaction

    Sang Jin Lee1, Nan Young Lee2, Eun Joo Lee3, Ji Ae Jang3, Gun Woo Kim3 and Eon Jeong Nam2, 1Kyungpook National University Hospital, Daegu, Republic of Korea, 2Kyungpook National University Chilgok Hospital, Daegu, Republic of Korea, 3Daegu Fatima Hospital, Daegu, Republic of Korea

    Background/Purpose: Primary Sjögren’s syndrome (pSS) is a prototypical autoimmune disorder with lymphocytic infiltration of exocrine and non-exocrine epithelia, where complex interactions between innate and adaptive…
  • Abstract Number: 0377 • ACR Convergence 2024

    Improving Self-Management Support in Patients with Juvenile Idiopathic Arthritis

    Julia Harris1, Leslie Favier2, Emily Fox3, Michael Holland3, Cara Hoffart4, Maria Ibarra3, Jordan Jones4, Susan Parish2, Kara Remick-Erickson2 and Ashley Cooper4, 1Children's Mercy Kansas City, Overland Park, KS, 2Children's Mercy Kansas City, Kansas City, 3Children's Mercy Hospital, Kansas City, MO, 4Children's Mercy Kansas City, Kansas City, MO

    Background/Purpose: Self-management support (SMS) is one of the key elements of the Chronic Care Model as it is an important aspect of the care for…
  • Abstract Number: 0446 • ACR Convergence 2024

    Rheum for Improvement: Contraception Counseling and Adherence in Patients with Lupus and Rheumatoid Arthritis on Teratogenic Medications

    Kathryn Kompa1 and Vasileios Kyttaris2, 1Beth Israel Deaconess Medical Center, Boston, MA, 2BIDMC, Boston, MA

    Background/Purpose: Methotrexate (MTX) and mycophenolate (MMF) are two common medications for both lupus (SLE) and rheumatoid arthritis (RA). Both medications are contraindicated in pregnancy, necessitating…
  • Abstract Number: 0380 • ACR Convergence 2024

    Joint Acoustic Emissions as a Digital Biomarker for Knee Inflammation in Juvenile Idiopathic Arthritis: A Pilot Study Using Musculoskeletal Ultrasound as Ground Truth

    Quentin Goossens1, Christopher Nichols1, Diana Sofia Villacis-Nunez2, Lori Ponder3, Omer Inan4 and Sampath Prahalad5, 1Georgia Institute of Technology, Atlanta, GA, 2Emory University School of Medicine, Atlanta, GA, 3Children's Healthcare of Atlanta, Atlanta, GA, 4Georgia Institute of Technology, Marietta, GA, 5Emory + Children's Pediatric Institute, Atlanta, GA

    Background/Purpose: Juvenile idiopathic arthritis (JIA) is a chronic childhood arthropathy affecting 1 in 1000 children under 16, classified into seven categories by ILAR. Commonly, JIA…
  • Abstract Number: 0274 • ACR Convergence 2024

    Cost-effectiveness of Low Dose Colchicine Prophylaxis When Starting Allopurinol Using the “Start-Low Go-Slow” Approach for Gout

    Yana Pryymachenko1, Ross Wilson1, Haxby Abbott1, Nicola Dalbeth2 and Lisa Stamp3, 1University of Otago, Dunedin, New Zealand, 2University of Auckland, Auckland, New Zealand, 3University of Otago, Christchurch, Christchurch, New Zealand

    Background/Purpose: To investigate the cost-effectiveness of low-dose colchicine prophylaxis for reducing gout flares when starting allopurinol using the “start-low go-slow” approach.Methods: This was a pre-planned…
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