ACR Meeting Abstracts

ACR Meeting Abstracts

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  • Abstract Number: 0003 • ACR Convergence 2024

    CLN-978, a CD19-directed T Cell Engager (TCE), Leads to Rapid and Deep B Cell Depletion and Has Broad Potential for Development in Autoimmune Diseases

    Máire F. Quigley1, Jennifer S. Michaelson1, Jeffrey Jones1, Farrukh T. Awan2, Geoffrey P. Shouse3, Yue Zhang1, Todd Shearer1, Judy Inumerable1, Irina M. Shapiro1, Patrick A. Baeuerle1 and Stephen Wax1, 1Cullinan Therapeutics, Inc., Cambridge, 2UT Southwestern Medical Center, Dallas, 3City of Hope Comprehensive Cancer Center, Duarte

    Background/Purpose: CD19-directed CAR T cell therapy has been reported to induce profound B cell depletion and deep clinical responses, including drug-free remission, in patients with…
  • Abstract Number: 0001 • ACR Convergence 2024

    Type I Interferon and Anifrolumab Effects on Bone Marrow and Blood Plasma Cells in Systemic Lupus Erythematosus

    Diana Alzamareh1, Nida Pellett2, Daria Krenitsky2, Wesley Durrett1, Javier Rangel-Moreno1, Jennifer Anolik2 and Jennifer Barnas1, 1University of Rochester, Rochester, NY, 2University of Rochester Medical Center, Rochester, NY

    Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of pathogenic anti-nuclear antibodies (ANA) by plasma cells (PC).  Importantly, long-lived plasma…
  • Abstract Number: 0160 • ACR Convergence 2024

    Supplement Use in a Diverse Cohort of Individuals with SLE

    Russell Ellyson1, Jinoos Yazdany2, S. Sam Lim3, Brad Pearce3 and Laura Plantinga4, 1Alameda Health System, Highland Hospital, Oakland, CA, 2UCSF, San Francisco, CA, 3Emory University, Atlanta, GA, 4University of California, San Francisco, San Francisco, CA

    Background/Purpose: Supplement use among individuals with SLE is not well-characterized, despite potential effects of some supplements on SLE activity or on treatments for SLE or…
  • Abstract Number: 0159 • ACR Convergence 2024

    Prevalence and Potential Factors Associated with Polypharmacy in Individuals with Systemic Lupus Erythematosus

    Jianing Yang1, Jinoos Yazdany2, S. Sam Lim3, Brad Pearce3 and Laura Plantinga4, 1Highland Hospital, AHS, San Leandro, CA, 2UCSF, San Francisco, CA, 3Emory University, Atlanta, GA, 4University of California, San Francisco, San Francisco, CA

    Background/Purpose: Polypharmacy is associated with an increased risk of adverse drug effects and medication nonadherence. However, the prevalence of polypharmacy and the medications and factors…
  • Abstract Number: 0126 • ACR Convergence 2024

    Underdiagnosis Prediction Fingerprint for Antiphospholipid Syndrome Derived from Electronic Health Record Data

    Emily Balczewski1, Amala Ambati2, Wenying Liang1, Jacqueline Madison1, Yu Zuo1, Karandeep Singh3 and Jason Knight1, 1University of Michigan, Ann Arbor, MI, 2University of Michigan, Toledo, OH, 3University of California -- San Diego, San Diego, CA

    Background/Purpose: Antiphospholipid syndrome (APS) is a rare autoimmune disease that is likely to demonstrate improved outcomes with earlier diagnosis and treatment. However, given APS’s complex,…
  • Abstract Number: 0196 • ACR Convergence 2024

    Associations Between Systemic Lupus Erythematosus (SLE) and the Social Vulnerability Index (SVI)

    Zoe Reed1, Xana Howard1, Cristina Arriens1, Teresa Aberle1, Wade DeJager2, Joan Merrill3 and Judith James1, 1Oklahoma Medical Research Foundation, Oklahoma City, OK, 2Oklahoma Medical Research Foundation, Oklahoma City, 3Oklahoma Medical Research Foundation, Oklahoma City 73104, OK

    Background/Purpose: Systemic lupus erythematosus (SLE) is a complex autoimmune disease that disproportionately affects young women of certain racial and ethnic minority groups with enhanced severity…
  • Abstract Number: 0211 • ACR Convergence 2024

    Characteristics of Hospitalizations and Outpatient Follow-up for Patients with SLE at an Academic Hospital Setting in Austin, Texas

    Riti Kotamarti1 and Veena Patel2, 1Dell Seton Medical Center, Austin, TX, 2Dell Medical School - UT Health Austin, Austin, TX

    Background/Purpose: Patients with SLE have high rates of hospitalizations annually and require careful coordination of care in both the inpatient and outpatient setting. Prior analyses…
  • Abstract Number: 0161 • ACR Convergence 2024

    Cross Country Burden of Osteoarthritis in Latin America and Caribbean from 1990-2021: A Comparative and Consistent Benchmarking Analysis for the Global Burden of Disease Study 2022

    malay rathod1, Eva Kalra2, Rafael Sanchez-Dopazo,3, Janmay Vala4, Saif Syed5, Akhilesh Sharma6, Ashwinikumar Shandilya7, Asmita Gera8, Mohit Lakkimsetti9, Juhi Patel10, VISHRANT AMIN11 and Hardik Desai12, 1Monmouth Medical Center, Rutgers University, Ewing, NJ, 2Trident Medical Cente, Charleston, SC, 3Larkin Community Hospital Palm Springs Campus, Hialeah, FL, 4Terna Medical College, Navi Mumbai, Maharashtra, India, 5Royal college of Surgeons,Dublin,Ireland, Dublin, Dublin, Ireland, 6Adesh Institute of Medical Sciences and Research, Bhatinda, India, 7Rural Medical college. Pravara institute of medical sciences., Ahmednagar, India, 8Tianjin medical University, Tianjin, China, Tianjin, Tianjin, China (People's Republic), 9Mamata Medical College,Khammam, Khammam, Telangana, India, 10GMERS MEDICAL COLLEGE VALSAD, 382330, Gujarat, India, 11GMERS MEDICAL COLLEGE VALSAD, Ahmedabad, India, 12Gujarat Adani Institute of Medical Sciences, Bhuj, India

    Background/Purpose: Osteoarthritis (OA) poses a significant and escalating health challenge across Latin America and the Caribbean (LAC), driven by demographic shifts, lifestyle factors, and varying…
  • Abstract Number: 0225 • ACR Convergence 2024

    Prediction of Response to Therapies and Flares Based on Ultrasound Findings at Baseline in Psoriatic Arthritis: An Analysis on a Joint Level

    Ummugulsum Gazel1, Seyyid Bilal Acikgoz2, Ricardo Sabido-Sauri1, Ozun Bayindir Tsechelidis3, Sylvia Sangwa4, Elliot Hepworth1 and Sibel Aydin5, 1University of Ottawa, Ottawa, ON, Canada, 2University of Ottawa, Rheumatology, Ottawa, ON, Canada, 3Ottawa University, Ottawa, ON, Canada, 4The Ottawa Hospital Research Institute, Ottawa, Canada, 5University of Ottawa - Ottawa, Ottawa, ON, Canada

    Background/Purpose: It is not clear how to interpret when the ultrasound and physical examination do not agree on a joint level. In this study, we…
  • Abstract Number: 0041 • ACR Convergence 2024

    Disease Activity and Serological Inflammatory Markers Are Associated with TNF-a and IL-6-Induced Osteoclasts, but Not with RANKL-Induced Osteoclasts in Peripheral Blood Monocytes from Patients with Rheumatoid Arthritis

    Yokota Kazuhiro1, Yoshimi Aizaki1, Miyoko Sekikawa2, Hiroshi Kajiyama1, Yasuto Araki1, Yuho Kadono2, Yuji Akiyama1 and Toshihide Mimura1, 1Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Saitama, Japan, Iruma-gun, Saitama, Japan, 2Department of Orthopaedic Surgery, Saitama Medical University, Saitama, Japan, Iruma-gun, Saitama, Japan

    Background/Purpose: We previously reported that a combination of TNF-α and IL-6 induces mouse osteoclast (OC)-like cells and human OCs with bone resorption activity [Arthritis &…
  • Abstract Number: 0220 • ACR Convergence 2024

    Ultrasound-assessed Dactylitis as a Biomarker in the Early Diagnosis of Psoriatic Arthritis

    Otto Olivas-Vergara1, Raquel Largo2, Lina Martínez-Estupiñán3, Fredeswinda Romero-Bueno4, Olga Sánchez-Pernaute3, Javier R. Godo3, Maria del Carmen Fariña-Sabaris5, Belen Ruffin Vicente5, Carmen Herencia6, Aránzazu Mediero2, Agustina Criado Alcazar7, Pablo E. Borges1, Sheila Recuero-Díaz1, Andrea Alvear-Torres3, Amalia Gil3, Antía García-Fernández3, Ana Elena Hoyo Fernandez8, M. Isabel Sanchez-Barba8, M. Belen Ortega Trompeta8, Cristina Vazquez-Carballo9, Gabriel Herrero-Beaumont3 and ESPERANZA NAREDO10, 1Department of Rheumatology and Joint and Bone Research Unit. Hospital Universitario Fundación Jiménez Díaz and IIS-FJD, Madrid, Spain, 2Joint and Bone Research Unit. IIS-Fundación Jiménez Díaz, Madrid, Spain, 3Department of Rheumatology and Joint and Bone Research Unit. Hospital Universitario Fundación Jiménez Díaz and IIS-FJD. Autonomous University of Madrid, Madrid, Spain, 4Hospital Universitario Fundación Jiménez Díaz and IIS-FJD. Autonomous University of Madrid, Madrid, Spain, 5Department of Dermatology.Hospital Universitario Fundación Jiménez Díaz and IIS-FJD. Autonomous University of Madrid, Madrid, Spain, 6Joint and Bone Research Unit. IIS-Fundación Jiménez Díaz, M, Spain, 7Primary Care..Centro de Salud Paseo Imperial, Madrid, Spain, 8Primary Care.Centro de Salud Paseo Imperial, Madrid, Spain, 9Joint and Bone Research Unit. IIS-Fundación Jiménez Díaz. Autonomous University of Madrid, Madrid, Spain, 10Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain

    Background/Purpose: The primary objective of this prospective, longitudinal, observational study was to evaluate the predictive value of ultrasound (US)-detected elementary lesions of dactylitis together with…
  • Abstract Number: 0204 • ACR Convergence 2024

    Making Rheum for Palliative Care in Rheumatology: Perspectives of Rheumatology and Palliative Care Clinicians

    Shannon Herndon1, Jack Kimball1, Christopher Jones1 and David Leverenz2, 1Duke University Medical Center, Durham, NC, 2Duke University, Durham, NC

    Background/Purpose: Palliative care is underutilized in patients with severe rheumatic disease. We sought to describe the perspectives of rheumatology and palliative care clinicians on the…
  • Abstract Number: 0145 • ACR Convergence 2024

    Community Mobility in a Diverse Cohort of Individuals with Systemic Lupus Erythematosus

    Leila Milanfar1, Jinoos Yazdany2, Amanda Eudy3, Courtney Hoge4, Charmayne M. Dunlop-Thomas5, Patti Katz6 and Laura Plantinga7, 1University of California San Francisco, San Francisco, CA, 2UCSF, San Francisco, CA, 3Duke University, Raleigh, NC, 4Emory University, Atlanta, GA, 5Emory University School of Medicine, Department of Medicine, Division of Rheumatology, Atlanta, GA, 6UCSF, San Rafael, CA, 7University of California, San Francisco, San Francisco, CA

    Background/Purpose: Measurement of the extent to which individuals move throughout their community and participate in social activities (“community mobility”) can provide a snapshot of how…
  • Abstract Number: 0157 • ACR Convergence 2024

    Knowledge and Attitudes About Delta-9-tetrahydrocannabinol (THC) Impact Real-world Practice in an International Group of Rheumatologists

    Joanna Zeiger1, Patti Katz2, Mary-Ann Fitzcharles3, Stuart Kassan4, Teresa Simon5 and Kaleb Michaud6, 1Canna Research Foundation, Boulder, CO, 2UCSF, San Rafael, CA, 3McGill University, Montreal-West, Canada, 4National Jewish Health, Denver, CO, 5Physicians Research Center Consultant to ForWard, Toms River, NJ, 6University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Rheumatologists care for difficult to manage chronic diseases, necessitating adjustments to new treatments and evolving patient views. When making treatment decisions, rheumatologists incorporate clinical…
  • Abstract Number: 0207 • ACR Convergence 2024

    Investigation of Delays in Cancer Screening in RA

    Rebecca Brooks1, Cassondra Hulshizer2, Andrew C. Hanson3, Vanessa Kronzer1, John Davis1, Elena Myasoedova1 and Cynthia Crowson1, 1Mayo Clinic, Rochester, MN, 2Mayo Clinic, Utica, MN, 3Mayo Clinic, Rochester

    Background/Purpose: Recent studies have shown that RA patients have increased mortality due to cancer. Despite the increased mortality, few studies have investigated the completion of…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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