ACR Meeting Abstracts

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  • Abstract Number: 0921 • ACR Convergence 2020

    The Hospital Anxiety and Depression Scale in Patients with Systemic Sclerosis – A Psychometric and Factor Analysis in a Monocentric Cohort

    Alexandru Garaiman1, Carina Mihai1, Rucsandra Dobrota1, Suzana Jordan1, Britta Maurer2, Jan Flemming3, Oliver Distler4 and Mike Oliver Becker1, 1Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland, Zurich, 2Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Switzerland, Zurich, 3Department of Consultation-Liaison-Psychiatry and Psychosomatic Medicine, University Hospital Zurich, Zurich, Switzerland, Zurich, Switzerland, 4Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Switzerland, Zurich, Switzerland

    Background/Purpose: The Hospital Anxiety and Depression Scale (HADS) is a screening tool used in patients with different medical conditions. However, its validity, reliability and responsiveness…
  • Abstract Number: 0927 • ACR Convergence 2020

    Care Gap in Patients with Systemic Sclerosis with CXR Findings Suggestive of Fibrosis

    Sandeep Dhillon1, Jessica Kapralik2, Curtis Sobchak3, Nader Khalidi4, Martin Kolb5, Nathan Hambly2, Gerard Cox2, Karen Beattie4 and Maggie Larche4, 1McMaster University, Burlington, ON, Canada, 2McMaster University, Hamilton, 3McMaster University, St. Catharines, ON, Canada, 4McMaster University, Hamilton, ON, Canada, 5McMaster University and Firestone Institute for Respiratory Health, St Joseph's Healthcare, Hamliton, ON, Canada

    Background/Purpose: Lung involvement, including interstitial lung disease (ILD), is the leading cause of death in patients with systemic sclerosis (SSc). High resolution CT (HRCT) is…
  • Abstract Number: 0926 • ACR Convergence 2020

    Risk Factors for Fractures and Osteoporosis Among Patients with Systemic Sclerosis in a United States Cohort

    Sina Famenini1, Jamie Perin2, Kristin Wipfler3, Kaleb Michaud4 and Zsuzsanna McMahan5, 1Johns Hopkins School of Medicine, Baltimore, MD, 2JHUSPH, Baltimore, 3FORWARD, The National Databank for Rheumatic Diseases, Omaha, NE, 4University of Nebraska Medical Center, Omaha, NE, 5Johns Hopkins University, Baltimore

    Background/Purpose:Systemic sclerosis (SSc) is associated with several risk factors for osteoporosis and fractures due to malabsorption or malnutrition, physical disability, chronic inflammation, and use of…
  • Abstract Number: 0932 • ACR Convergence 2020

    Skeletal Muscle Involvement in Systemic Sclerosis Predisposes to Severe Gastrointestinal Tract and Cardiac Muscle Disease

    Reshad Mahmud1, Lei Zhu2, Maureen Laffoon2, Thomas Medsger3 and Robyn Domsic4, 1UPMC, Pittsburgh, PA, 2University of Pittsburgh, Pittsburgh, PA, 3University of Pittsburgh School of Medicine, Verona, PA, 4University of Pittsburgh School of Medicine, Pittsburgh, PA

    Background/Purpose: Tissues containing muscle cells are affected in systemic sclerosis (SSc) patients in different organ systems: skeletal muscle, cardiac muscle and gastrointestinal (GI) smooth muscle. …
  • Abstract Number: 0934 • ACR Convergence 2020

    Warfarin Use and Risk of Knee and Hip Replacements

    Priyanka Ballal1, Christine Peloquin1, Cindy Boer2 and Tuhina Neogi1, 1Boston University School of Medicine, Boston, MA, 2Erasmus Medical Center, Rotterdam, Netherlands

    Background/Purpose: Vitamin K is an essential co-factor in the post-translational gamma-carboxylation of glutamic acid to form gamma-carboxy-glutamic acid (Gla) residues. This confers functionality to vitamin…
  • Abstract Number: 0929 • ACR Convergence 2020

    The Effect of Mycophenolate Mofetil on Pulmonary Function Tests in Patients with Systemic Sclerosis-associated Interstitial Lung Disease, and the Difference Between the African Americans versus Non-African Americans

    Afroditi Boulougoura1, Shannon Lance2, Duncan Moore3, Haijun Wang4, Julio Huapaya5 and Virginia Steen3, 1Department of Internal Medicine, Medstar Georgetown University Hospital, Washington, DC, USA., Washington, DC, 2Department of Internal Medicine, Medstar Georgetown University Hospital, Washington, DC, USA., Washington, 3Division of Rheumatology, Department of Medicine, MedStar Georgetown University Hospital, Washington, DC, 4MedStar Health Research Institute, Washington, DC, USA, Washington, 5Department of Critical Care Medicine, National Institutes of Health, Bethesda, MD, USA., Bethesda

    Background/Purpose: Scleroderma-related interstitial lung disease (SSc-ILD) is a pulmonary fibrosing disorder characterized by systemic inflammation and progressive scarring of the lungs that leads to respiratory…
  • Abstract Number: 0924 • ACR Convergence 2020

    Towards Systemic Sclerosis Rehabilitation via Videogames

    Marica Doveri1, Marco Trombini2, Federica Ferraro3, Rossana Galli1, Anna Laura Bargeri4, Simone Rando1, SIlvana Dellepiane2 and Gerolamo Bianchi1, 1Hospital La colletta Arenzano(Genoa), Arenzano, Liguria, Italy, 2Department of Electrical, Electronics and Telecommunication Engineering and Naval Architecture (DITEN), University of Genoa, GENOVA, Liguria, Italy, 3Department of Electrical, Electronics and Telecommunication Engineering and Naval Architecture (DITEN), University of Genoa, Ponsacco, Liguria, Italy, 4Hospital La colletta Arenzano(Genoa), Arenzano, Italy

    Background/Purpose: The excessive production and accumulation of collagen in systemic sclerosis (SSc) leads to the gradual loss of mobility which affects the quality of life…
  • Abstract Number: 0937 • ACR Convergence 2020

    Late Cardiovascular Outcomes in Children with Kawasaki Disease: A Population-based Cohort Study

    Cal Robinson1, Rahul Chanchlani1, Anastasia Gayowsky2, Sandeep Brar3, Elizabeth Darling4, Catherine Demers4, Tapas Mondal1, Rulan Parekh5, Hsien Seow4 and Michelle Batthish1, 1McMaster Children's Hospital, Hamilton, ON, Canada, 2ICES McMaster, Hamilton, ON, Canada, 3University of California, San Fransisco, 4McMaster University, Hamilton, ON, Canada, 5University of Toronto, Toronto, Canada

    Background/Purpose: Kawasaki disease (KD) is a common childhood vasculitis associated with coronary artery aneurysms (CAA). Based on our recent work, the incidence of KD has…
  • Abstract Number: 0940 • ACR Convergence 2020

    In Patients with Inflammatory Arthritides Central Pain Sensitization Is Strictly Associated with Functional Disability

    Giovanni Adami1, Angelo Fassio1, Elisabetta Gerratana2, Alessandro Giollo1, Camilla Benini1, Luca Idolazzi1, Elisabetta Vantaggiato1, Davide Gatti1 and Maurizio Rossini1, 1Rheumatology Unit, University of Verona, Verona, Italy, 2Rheumatology Unit, University of Messina, Messina, Italy

    Background/Purpose: Long-term nociceptive pain, as in inflammatory arthritides, can cause Central Sensitization (CS) to pain. CS Inventory (CSI) is a validated screening instrument for clinicians to…
  • Abstract Number: 0941 • ACR Convergence 2020

    MDHAQ/RAPID3 (multidimensional Health Assessment Questionnaire/routine Assessment of Patient Index Data) Levels Are Elevated in Rheumatology Patients Who Meet 2011 Fibromyalgia (FM) or MDHAQ/FAST3 (fibromyalgia Assessment Screening Tool) Criteria

    Juan Schmukler1, Tengfei Li2, Kyle Schroeder3 and Theodore Pincus3, 1Mount Sinai Hospital Chicago, IL, Chicag, IL, 2Georgetown University, Washigton, 3Rush University Medical Center, Chicago, IL

    Background/Purpose: RAPID3 (routine assessment of patient index data) on an MDHAQ (multiple multidimensional health assessment questionnaire) was developed initially to assess patients with rheumatoid arthritis…
  • Abstract Number: 0936 • ACR Convergence 2020

    Urine Proteomics and Single Cell Transcriptomics Identify IL-16 as a Biomarker for Lupus Nephritis

    Andrea Fava1, Jill Buyon2, Chandra Mohan3, Ting Zhang3, H. Michael Belmont4, Peter Izmirly5, Robert Clancy6, Jose Monroy-Trujillo7, Celine Berthier8, Anne Davidson9, Nir Hacohen10, David Wofsy11, Deepak Rao12, Soumya Raychaudhuri13, The Accelerating Medicines Partnership in SLE Network14, William Apruzzese15 and Michelle Petri16, 1Johns Hopkins University, Baltimore, MD, 2Department of Medicine, NYU School of Medicine, New York, NY, 3UT Houston, Houston, 4New York University, New York, NY, 5Department of Medicine, New York University School of Medicine, New York, NY, 6NYU School of Medicine, New York, 7Johns Hopkins University, Baltimore, 8University of Michigan, Ann Arbor, 9Northwell Health, New York, 10Broad Institute, Boston, 11University of California San Francisco, San Francisco, CA, 12Brigham and Women's Hospital, Boston, MA, 13Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, 14Multiple Institutions, Multiple Cities, 15., Boston, 16Johns Hopkins University School of Medicine, Timonium, MD

    Background/Purpose: Treatment of lupus nephritis relies on renal histopathological features. However, renal biopsies do not capture patient-specific active biological pathways. Urine proteomic biomarkers could revolutionize…
  • Abstract Number: 0947 • ACR Convergence 2020

    STING Gain-of-Function in Radio-resistant Cells Supports a Lymphocyte Dependent Auto-inflammatory Lung Disease

    Kevin Gao1, Mona Motwani1, Ann Marshak-Rothstein2 and Katherine Fitzgerald1, 1University of Massachusetts medical school, worcester, MA, 2University of Massachusetts medical school, Newton, MA

    Background/Purpose: cGAS-STING is a cytosolic dsDNA sensing pathway whose regulation is vital to immune homeostasis. Pediatric patients with constitutively active STING mutations develop an autoinflammatory…
  • Abstract Number: 0944 • ACR Convergence 2020

    Obstructive Sleep Apnea in Fibromyalgia Patients: A Meta-analysis

    Nouran Eshak1, Wasawat Vutthikraivit1, Asmaa Beltagy2 and John Pixley3, 1Texas Tech Health Science Center, Lubbock, TX, 2Faculty of Medicine, Alexandria University, alexandria, egypt, Egypt, 3Texas Tech University HSC, Lubbock, TX

    Background/Purpose: Fibromyalgia is a chronic pain disorder prevalent in about 3% of the population, mostly in females. A common complaint is non-restorative sleep.  Obstructive sleep…
  • Abstract Number: 0939 • ACR Convergence 2020

    Maintenance of Remission After Withdrawal of Etanercept or Methotrexate in Patients with Rheumatoid Arthritis in Sustained Remission on Combination Therapy: Results from a Randomized, Double-blind, Controlled Trial

    Jeffrey R Curtis1, Paul Emery2, Elaine Karis3, Boulos Haraoui4, Vivian Bykerk5, Priscilla Yen3, Gregory Kricorian6 and James Chung3, 1Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 2Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK, Leeds, United Kingdom, 3Amgen, Inc., Thousand Oaks, CA, 4Rheumatology Institute of Montréal, Montreal, Canada, 5Hospital for Special Surgery, New York, NY, 6Amgen Inc., Thousand Oaks, CA

    Background/Purpose: Rheumatoid arthritis (RA) patients (pts) in remission on combination therapy (Combo) of methotrexate (MTX)+etanercept (ETN) face ongoing medication burden and long-term safety/tolerability concerns related…
  • Abstract Number: 0831 • ACR Convergence 2020

    Sociodemographic, Disease, and Medication Profile of RA Patients Under 65 Years Compared with 65 Years or Older at Registry Enrollment: Real World Results from a Rheumatoid Arthritis Cohort

    Mohammad Movahedi1, Angela Cesta2, Xiuying Li3 and Claire Bombardier4, 1Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada, 2Toronto General Hospital Research Institute, Toronto, ON, Canada, 3Toronto General Hospital Research Institute, Toronto, Canada, 4Institute for Work and Health, Toronto, ON, Canada

    Background/Purpose: Age is an important factor that can affect disease course, physical function and treat to target strategy for patients with rheumatoid arthritis (RA). We…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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