Abstracts Archive - Page 664 of 2607 - ACR Meeting Abstracts

Abstract Number: 1961 • ACR Convergence 2022
COVID-19 mRNA Vaccine Induced Antibody Titers and IFN-g Responses Are Decreased in Persons with Rheumatoid Arthritis and Older Age
Holly Dudley¹, megan O'Mara², Ann Auma¹, Jenny Gong³, Yael Ross⁴, Natalie Gurevich², Larraine Gordesky⁵, Nora Singer⁶, Lenche Kostadinova⁷, Brigid Wilson⁷, David Zidar⁷, Christopher King¹, David Canaday¹, Carey Shive¹, Maya Mattar⁸ and Donald Anthony⁹, ¹Case Western Reserve University, Cleveland, OH, ²Cleveland Veteran Affairs Medical Center, Cleveland, OH, ³Case Western School of Medicine, Cleveland, OH, ⁴Case Western Reserve University at MetroHealth Medical Center, Atlanta, GA, ⁵MetroHealth Medical Center, Cleveland, OH, ⁶The MetroHealth System at Case Western Reserve University School of Medicine, Cleveland, OH, ⁷VA Medical Center, Cleveland, OH, ⁸Louis Stokes VA Medical Center, Mayfield Heights, OH, ⁹Case, VA, Metro, Chardon, OH
Background/Purpose: People with autoimmune diseases have worse outcomes if infected by SARS-CoV2. In particular, persons with rheumatoid arthritis (RA), have lower antibody responses to COVID-19…
Abstract Number: 1959 • ACR Convergence 2022
Increased Mortality in Patients with RA-Associated Interstitial Lung Disease: Data from a French Administrative Healthcare Database
Pierre-Antoine Juge¹, Lidwine Wemeau², Sebastien Ottaviani³, guillaume desjeux⁴, Joe Zhuo⁵, Virginie Vannier-Moreau⁶, René-Marc Flipo⁷, Bruno Crestani⁸ and Philippe Dieude⁹, ¹Rheumatology department, Bichat Hospital, Paris, France, ²Pulmonology department, Lille University hospital, Lille, France, ³Hopital Bichat-Claude Bernard, Paris, France, ⁴e-Health Services Sanoia, Gemenos, France, ⁵BMS, Lawrenceville, NJ, ⁶BMS, Rueil-Malmaison, ⁷Hôpital Roger Salengro, Lille, France, ⁸Hopital Bichat, Paris University, Paris, France, ⁹Université Paris Cité, Paris, France
Background/Purpose: Interstitial lung disease (ILD) is a common extra-articular manifestation of RA. Studies have shown variability in the prevalence and mortality rate of patients with…
Abstract Number: 1964 • ACR Convergence 2022
Systematic Screening of Multimorbidities Results in an Increased Intake of Comorbidity Preventive Medications and a Decreased Hospitalization Rate
Claire DAIEN¹, Vera Georgescu², Guillaume Decarriere³, Jenica Pastor³, Gaël Mouterde⁴, Cédric Lukas⁵, Grégoire Mercier³ and Jacques Morel⁶, ¹University Hospital, Saint-Gély-du-Fesc, France, ²Unité de Recherche Médico-économique, CHU de Montpellier et Université de Montpellier, Montpellier, France, ³CHU Montpellier, Montpellier, France, ⁴Lapeyronie Hospital, Montpellier, France, ⁵University Hospital Centre Montpellier, University of Montpellier, Montpellier, France, ⁶University and CHU Montpellier, Montpellier, France
Background/Purpose: A systematic screening of multimorbidities is performed since 2014 at the Montpellier University Hospital in patients with chronic inflammatory rheumatic diseases (IRD). The objective…
Abstract Number: 1963 • ACR Convergence 2022
Lipid Screening and Statin Use in Rheumatoid Arthritis Patients in an Underserved Population
Colleen O'Neill¹ and Veena Patel², ¹Dell Medical School - UTHealth Austin, Austin, TX, ²Dell Medical School - UT Health Austin, Austin, TX
Background/Purpose: Patients with rheumatoid arthritis (RA) have an increased risk of atherosclerotic cardiovascular disease (ASCVD) compared to the general population and RA is considered a…
Abstract Number: 1966 • ACR Convergence 2022
Favorable Effects of TNF Inhibitors on Intima Media Thickness and Arterial Stiffness in Rheumatoid Arthritis: A Systematic Review and Meta-analysis
Eva van Geel¹, Bafrin Abdulmajid¹, Annelies Blanken² and Michael Nurmohamed³, ¹Reade Rheumatology Center, Amsterdam, Netherlands, ²Amsterdam University Medical Centers, Amsterdam, Netherlands, ³Amsterdam University Medical Center, Kortenhoef, Netherlands
Background/Purpose: Controlling inflammation with tumour necrosis factor (TNF) inhibitors in rheumatoid arthritis (RA) patients is hypothesized to reduce their cardiovascular risk. Arterial wall thickness (carotid…
Abstract Number: 1967 • ACR Convergence 2022
Sex Differences in Employment Outcomes in Patients with Recent Onset Rheumatoid Arthritis
Carol Hitchon¹, Marie-France Valois², orit schieir², Louis Bessette³, Gilles Boire⁴, Susan Bartlett⁵, Glen Hazlewood⁶, Edward Keystone⁷, Janet Pope⁸, Carter Thorne⁹, Diane Tin¹⁰ and Vivian Bykerk¹¹, ¹University of Manitoba, Winnipeg, MB, Canada, ²McGill University, Montréal, QC, Canada, ³Centre de l'Ostoporose et de Rhumatologie de Québec, Québec, QC, Canada, ⁴Universite de Sherbrooke, Sherbrooke, QC, Canada, ⁵McGill University, Montreal, QC, Canada, ⁶University of Calgary, Calgary, AB, Canada, ⁷Keystone Consulting Enterprises Inc., Toronto, ON, Canada, ⁸University of Western Ontario, London, ON, Canada, ⁹Southlake Regional Health Centre, Newmarket, ON, Canada, ¹⁰The Arthritis Program Research Group, Newmarket, ON, Canada, ¹¹Hospital for Special Surgery, New York, NY
Background/Purpose: Early work cessation and reduced work and activity productivity are significant contributors to the personal and societal costs associated with rheumatoid arthritis (RA). We…
Abstract Number: 1958 • ACR Convergence 2022
The Increased Risk of Staphylococcus Aureus Bacteremia in Rheumatoid Arthritis – What Is the Impact of Glucocorticoids, Biologic Disease-Modifying Anti-Rheumatic Drugs and Disease Activity: A Danish Nationwide Nested Case-Control Study in the DANBIO Registry
Sabine Dieperink¹, Bente Glintborg², Frank Mehnert³, Mette Nørgaard³, Louise Bruun Oestergaard⁴, Thomas Benfield⁵, Christian Torp-Pedersen⁶, Andreas Petersen⁷ and Merete Lund Hetland¹, ¹Copenhagen University Hospital - Rigshospitalet, Glostrup, Denmark, ²Rigshospitalet, Glostrup, Virum, Denmark, ³Aarhus University Hospital, Aarhus, Denmark, ⁴Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark, ⁵Copenhagen University Hospital - Amager and Hvidovre, Copenhagen, Denmark, ⁶Copenhagen University Hospital - North Zealand, Copenhagen, Denmark, ⁷Statens Serum Institut, Copenhagen, Denmark
Background/Purpose: Staphylococcus aureus bacteremia (SAB) has high mortality.[1] We have previously identified an approximately doubled risk in patients with rheumatoid arthritis (RA),[2] but the role…
Abstract Number: 1969 • ACR Convergence 2022
The Potential Diagnostic Value of C-X-C Motif Chemokine 13 (CXCL13) in Seronegative Arthritis
Silvia Piantoni¹, Fabrizio Angeli¹, Francesca Regola², Franco Franceschini² and Paolo Airò³, ¹Rheumatology and Clinical Immunology Unit, Department of Clinical and Experimental Sciences, ASST Spedali Civili and University of Brescia, Brescia, Italy, ²Rheumatology and Clinical Immunology Unit, ASST Spedali Civili and University of Brescia, Brescia, Italy, ³Rheumatology and Clinical Immunology Unit, ASST Spedali Civili, Brescia, Italy
Background/Purpose: The finding of circulating biomarkers in the field of chronic arthritis is still an unmet need, especially for the subgroup of seronegative arthritis [e.g.,…
Abstract Number: 1970 • ACR Convergence 2022
Detecting Inflammatory Changes in Seronegative Inflammatory Arthritis with Use of Musculoskeletal Ultrasound Studies
Clarice P. Lin¹ and Richard C. Chou², ¹University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Department of Medicine, Buffalo, NY, ²University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Division of Allergy, Immunology, & Rheumatology, Department of Medicine, Buffalo, NY
Background/Purpose: Recent clinical practice has increasingly utilized musculoskeletal (MS) ultrasound studies to assess inflammation and soft-tissue abnormalities of the joints, such as synovitis and bone…
Abstract Number: 1972 • ACR Convergence 2022
Comprehensive Investigation of Pain and Inflammation in Rheumatoid Arthritis from a Multidisciplinary Approach
Lilla Tóth¹, Gergely Orsi², Krisztina Csókási³, Gábor Sütő⁴, Gábor Kumánovics⁵, Noémi Császár-Nagy⁶, Szabolcs Takács⁷, Eszter Szigedi⁸, Zsófia Nagy⁸, Zsolt Hodovány⁸, Lili Duzsik⁸, Zoltán Vidnyánszky⁹, József Kun¹⁰, Péter Urbán¹⁰, György Nagy¹¹ and Zsuzsanna Helyes¹², ¹Department of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, Pécs, Hungary, ²MTA-PTE Clinical Neuroscience MR Research Group, Eötvös Loránd Research Network (ELKH); Department of Neurology, Medical School, University of Pecs, Pécs, Hungary, ³Institute of Psychology, Faculty of Humanities and Social Sciences, University of Pécs, Pécs, Hungary, ⁴Second Department of Medicine and Nephrology-Diabetes Centre, University of Pécs, Pécs, Hungary, ⁵Department of Rheumatology and Immunology, University of Pécs, Pécs, Hungary, ⁶National University of Public Services; Psychosomatic Outpatient Clinics, Budapest, Hungary, ⁷Department of Psychology, Karoly Gaspar University, Budapest, Hungary, ⁸Psychosomatic Outpatient Clinics, Budapest, Hungary, ⁹Brain Imaging Centre, Research Centre for Natural Sciences, Budapest, Hungary, ¹⁰Szentágothai Research Centre, Bioinformatics Research Group, Genomics and Bioinformatics Core Facility, University of Pécs, Pécs, Hungary, ¹¹Department of Rheumatology and Clinical Immunology, Department of Internal Medicine and Oncology, Semmelweis University; Department of Genetics, Cell and Immunobiology, Semmelweis University; Heart and Vascular Centre, Semmelweis University, Budapest, Hungary, ¹²Department of Pharmacology and Pharmacotherapy, Medical School, University of Pécs; Szentágothai Research Centre and Centre for Neuroscience, University of Pécs, Pécs, Hungary
Background/Purpose: Despite the therapeutic advances of rheumatoid arthritis (RA), optimal disease control cannot be achieved in the difficult-to-treat (D2T) RA population, leading to the persistence…
Abstract Number: 1956 • ACR Convergence 2022
Functional Disabilities in Hands Precede Those in Feet in Patients Progressing from Clinically Suspect Arthralgia to Rheumatoid Arthritis; A Longitudinal Observational Study
Sarah J.H. Khidir¹, Bastiaan van Dijk², Marloes Verstappen¹, Elise van Mulligen³ and Annette van der Helm-van Mil⁴, ¹Leiden University Medical Center, Leiden, Netherlands, ²Leiden University Medical Centre (LUMC), Leiden, Netherlands, ³Erasmus Medical Center, Leiden University Medical Center, Rotterdam, Netherlands, ⁴Leiden University Medical Center, Erasmus Medical Center, Leiden, Netherlands
Background/Purpose: In the pre-arthritis phase of Rheumatoid Arthritis (RA), symptoms resulting in physical disabilities already occur. It is unknown whether functional disabilities start in hands…
Abstract Number: 1974 • ACR Convergence 2022
Which ACR Response Definition Should Be Used for Disease Activity Claims in Approval Studies of Rheumatoid Arthritis? A Systematic Evaluation
Andreas Kerschbaumer¹, Victoria Konzett², Josef Smolen¹ and Daniel Aletaha³, ¹Medical University of Vienna, Vienna, Austria, ²Division of Rheumatology / Department of Medicine III / Medical University of Vienna, Vienna, Austria, ³Medical University Vienna, Wien, Austria
Background/Purpose: The American College of Rheumatology (ACR) response definition was developed in 1995 by Felson et al. as a composite outcome and has been the…
Abstract Number: 1975 • ACR Convergence 2022
Identifying MicroRNAs Associated with Neuropathic Pain in Patients with Rheumatoid Arthritis (RA)
Lissette Delgado-Cruzata¹, Milena Rodriguez Alvarez², Veronika Zenkeviciute³, Nickolas Almodovar³ and Toni-Ann Bravo³, ¹City University of New York, New York, NY, ²SUNY Downstate Medical Center, New York, NY, ³John Jay College, CUNY, New York, NY
Background/Purpose: Neuropathic pain is one of the most common clinical characteristics of rheumatoid arthritis (RA). It often does not subside with the use of DMARD,…
Abstract Number: 1977 • ACR Convergence 2022
Tc99m Tilmanocept Imaging Predicts Clinical Response in Rheumatoid Arthritis Patients Beginning New Anti-TNFα Therapy
Jonathan Graf¹, Martin Jacobs², Debbie Gladd-Foley³, Yelliann Ruiz-Irizarry⁴, Alan Kivitz⁵, Melvin Churchill⁶, Arash Kardan⁷, Mara Leach⁸, David Ralph⁸, Nicole Korczak⁸, Addison Hasselbach⁸, Bonnie Abbruzzese⁸, Rachael Hershey⁸, Beth Potter⁸, Jessica Fitzpatrick⁸, Aaron Thornton⁸, Michael Blue⁸ and Michael Rosol⁸, ¹Ucsf, San Francisco, CA, ²Kettering Network Radiologists, Kettering, OH, ³Premier Rheumatology of Oklahoma, Tulsa, OK, ⁴Jackson Health System, Innovation Medical Research Center, Palmetto Bay, FL, ⁵Department of Rheumatology, Altoona Center for Clinical Research, Duncansville, PA, ⁶Arthritis Center of Nebraska, Bryan Health, Lincoln, NE, ⁷Baylor College of Medicine, Department of Radiology, Houston, TX, ⁸Navidea Biopharmaceuticals, Dublin, OH
Background/Purpose: Effective and expeditious control of rheumatoid arthritis (RA) disease activity using a treat-to-target (T2T) strategy is crucial to prevent long term damage and disability.…
Abstract Number: 1978 • ACR Convergence 2022
Using Administrative Health Data to Construct a Frailty Index as a Measure of Susceptibility to Adverse Health Outcomes Among Individuals with Rheumatoid Arthritis
Alexandra Legge¹ and Diane Lacaille², ¹Arthritis Research Canada, Dalhousie University, Halifax, NS, Canada, ²Arthritis Research Canada, University of British Columbia, Vancouver, BC, Canada
Background/Purpose: Frailty is increasingly recognized among individuals living with RA. While several tools are available to assess frailty in clinical settings, it is less readily…

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