Abstracts Archive - Page 656 of 2425 - ACR Meeting Abstracts

Abstract Number: 0423 • ACR Convergence 2020
Defining Ear Chondritis: Data from 685 Patients with Relapsing Polychondritis
Marcela Ferrada¹, Nathalie Costedoat-Chalumeau², Guillaume Moulis³, Nancy Linn⁴, Emily Rose¹ and Peter C. Grayson⁵, ¹Systemic Autoimmunity Branch, Vasculitis Translational Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ²APHP, Université de Paris, Paris, France, ³Toulouse University hospital, Toulouse, France, ⁴Relapsing Polychondritis Foundation, Palos Verdes Estates, CA, ⁵Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Bethesda, MD
Background/Purpose: Ear chondritis is often considered the pathognomonic feature of relapsing polychondritis (RP). Although painful redness and swelling of the pinna and a resultant cauliflower…
Abstract Number: 0418 • ACR Convergence 2020
Prevalence of Thyroid Disease Among Patients with Vasculitis
Tanaz Kermani¹, David Cuthbertson², Simon Carette³, Nader Khalidi⁴, Curry L. Koening⁵, Carol Langford⁶, Carol McAlear⁷, Paul Monach⁸, Larry Moreland⁹, Christian Pagnoux¹⁰, Philip Seo¹¹, Ulrich Specks¹², Antoine Sreih¹³, Kenneth Warrington¹² and Peter Merkel¹³, ¹David Geffen School of Medicine / University of California, Los Angeles, CA, ²University of South Florida, Tampa, ³Division of Rheumatology, Mount Sinai Hospital and University Health Network, University of Toronto, Toronto, ON, Canada, ⁴McMaster University, Hamilton, ON, Canada, ⁵University of Utah, Salt Lake City, ⁶Cleveland Clinic, Moreland Hills, OH, ⁷University of Pennsylvania, Philadelphia, ⁸Brigham and Women's, Boston, ⁹University of Pittsburgh, Denver, CO, ¹⁰Division of Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ¹¹Johns Hopkins University, Baltimore, MD, ¹²Mayo Clinic, Rochester, MN, ¹³University of Pennsylvania, Philadelphia, PA
Background/Purpose: Previous studies have reported higher risk of thyroid disease in patients with giant cell arteritis (GCA) and ANCA-associated vasculitis (AAV) compared to age- and…
Abstract Number: 0413 • ACR Convergence 2020
Coronavirus Infection and Vasculitis: Identifying Associations Mining the Biomedical Literature
Alicia Rodriguez Pla¹ and Rodrigo Cartin-Ceba², ¹Rheumatology. Mayo Clinic Arizona, Scottsdale, ²Pulmonary. Mayo Clinic Arizona, Scottsdale, AZ
Background/Purpose: Based on recent publications suggesting an association between COVID-19 and vascular inflammation, our aim was to explore new associations between coronavirus infections and vasculitis…
Abstract Number: 0427 • ACR Convergence 2020
Validation of Physician Global Assessment as an Outcome Measure in Relapsing Polychondritis
Emily Rose¹, Marcela Ferrada¹, Kaitlin Quinn², Wendy Goodspeed¹, Laurent Arnaud³ and Peter C. Grayson⁴, ¹Systemic Autoimmunity Branch, Vasculitis Translational Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, BETHESDA, MD, ²Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Washington, DC, ³Department of rheumatology, University Hospitals of Strasbourg and French National Reference Center for Rare Auto-immune diseases, Strasbourg, Alsace, France, ⁴Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Bethesda, MD
Background/Purpose: Relapsing polychondritis (RP) is a rare systemic inflammatory disorder of cartilage that lacks validated disease activity measures. Physician global assessment (PhGA) is a measure…
Abstract Number: 0426 • ACR Convergence 2020
T-Cell Receptor (TCR) Sequencing Reveals Decreased Diversity and Clonotypic Expansion of T-cells in Relapsing Polychondritis (RP)
Emily Rominger¹, Sufia Bakshi², Emily Rose³, Marcela Ferrada³, Peter C. Grayson⁴, Robert Colbert⁵ and Keith Sikora⁶, ¹Systemic Autoimmunity Branch, Vasculitis Translational Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, ²National Institutes of Health, Bethesda, MD, ³Systemic Autoimmunity Branch, Vasculitis Translational Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ⁴Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Bethesda, MD, ⁵Pediatric Clinical Trials Unit and Office of Clinical Director, NIAMS, NIH, Bethesda, MD, ⁶National Institutes of Health Clinical Center, Bethesda, MD
Background/Purpose: Relapsing polychondritis (RP) is a rare, systemic inflammatory disease characterized by recurrent inflammation of cartilaginous structures, including the nose/ears, joints, and trachea. The etiology of…
Abstract Number: 0432 • ACR Convergence 2020
The Effect on Renal Function of the Complement C5a Receptor Inhibitor Avacopan in ANCA-Associated Vasculitis
Peter Merkel¹, Pirow Bekker², Huibin Yue², Catherine Kelleher², Thomas Schall² and David Jayne³, ¹University of Pennsylvania, Philadelphia, PA, ²ChemoCentryx, Mountain View, CA, ³Department of Medicine, Vasculitis and Lupus Research Group, University of Cambridge, Cambridge, UK, Cambridge, United Kingdom
Background/Purpose: Avacopan, a novel, orally-administered selective antagonist of C5aR, was recently evaluated in a pivotal Phase 3 randomized clinical trial where its use in patients…
Abstract Number: 0431 • ACR Convergence 2020
Hydroxychloroquine Use Was Not Associated with QTc Length in a Large Cohort of SLE and RA Patients
Elizabeth Park¹, Jon Giles², Thania Perez-Recio¹, Paloma Pina³, Christopher Depender¹, Joan Bathon¹ and Laura Geraldino-Pardilla⁴, ¹Division of Rheumatology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, ²Columbia University, New York, NY, ³Cardiac Electrophysiology, Northwestern Medicine, Chicago, IL, ⁴Division of Rheumatology, Columbia University Vagelos College of Physicians and Surgeons, New York
Background/Purpose: Hydroxychloroquine (HCQ) is a cornerstone therapy for systemic lupus erythematosus (SLE), and is used as monotherapy and combined with other DMARDs in rheumatoid arthritis…
Abstract Number: 0437 • ACR Convergence 2020
Integrating Reproductive Health in Systemic Lupus Erythematosus in a Tertiary Care Setting
Jun Chu¹, Sarthak Gupta¹, Zerai Manna², Michael Davis¹, Yenealem Temesgen-Oyelakin¹, Elaine Poncio¹, Isabel Ochoa¹, Laura Lewandowski³, Mariana Kaplan⁴, Alan Decherney¹ and Sarfaraz Hasni², ¹National Institutes of Health, Bethesda, MD, ²Lupus Clinical Trials Unit, NIAMS/NIH, Bethesda, MD, ³NIAMS, NIH, Rockville, MD, ⁴National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD
Background/Purpose: Systemic Lupus Erythematosus (SLE) predominantly affects women of childbearing age. Women affected by SLE have higher risk for infertility, miscarriages, and other pregnancy complications…
Abstract Number: 0439 • ACR Convergence 2020
Hurried Communication and Low Patient Self-Efficacy Are Associated with Persistent Non-Adherence to SLE Medications
Ann Cameron Barr¹, Megan Clowse², Amanda Eudy³, Jennifer Rogers⁴, Rebecca Sadun³, Lisa Criscione-Schreiber⁵, Jayanth Doss³, Lena Eder⁶, Mithu Maheswaranathan³, Amy Corneli⁷, Hayden Bosworth⁷ and Kai Sun³, ¹Duke University Hospital, Durham, NC, ²Duke University, Chapel Hill, NC, ³Duke University, Durham, NC, ⁴Duke, Durham, NC, ⁵Duke University School of Medicine, Durham, NC, ⁶Duke University Hospital, Chapel Hill, NC, ⁷Duke University, Durham
Background/Purpose: Medication non-adherence is common among SLE patients and contributes to poor outcomes. Underrepresented racial minorities have disproportionately lower rates of medication adherence and often…
Abstract Number: 0434 • ACR Convergence 2020
Changes in Mental Health During the COVID-19 Pandemic Among Individuals with Rheumatic Disease
Patricia Katz¹, Sofia Pedro², Kristin Wipfler³, Teresa Simon⁴, Yomei Shaw⁵, Adam Cornish⁶ and Kaleb Michaud⁷, ¹University of California, San Francisco, Novato, CA, ²FORWARD-The National Data Bank for Rheumatic Diseases, Wichita, ³FORWARD, The National Databank for Rheumatic Diseases, Omaha, NE, ⁴Bristol-Myers Squibb Company (at time of analysis), Princeton, NJ, ⁵Forward, The National Databank for Rheumatic Diseases, East Lansing, MI, ⁶FORWARD, 68134, NE, ⁷University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Symptoms of both depression and anxiety are often elevated among individuals with rheumatic conditions, and stress levels may play a role in each. Depression,…
Abstract Number: 0429 • ACR Convergence 2020
Prothrombotic Antiphospholipid Antibodies in COVID-19
Yu Zuo¹, Shanea Estes², Alex Ghandi³, Srilakshmi Yalavarthi³, Ramadan Ali³, Shi Hui³, Gautam Sule³, Kelsey Gockman³, Jacqueline Madison³, Melanie Zuo³, Wrenn Woodard³, Sean Lezak³, Njira Lugogo³, Yogendra Kanthi⁴ and Jason Knight¹, ¹Division of Rheumatology, University of Michigan, Ann Arbor, MI, ²University of Michigan, Ann Arbor, MI, ³University of Michigan, Ann Arbor, ⁴Division of Cardiovascular Medicine, Ann Arbor
Background/Purpose: Patients with coronavirus disease 19 (COVID-19) are at high risk for thrombosis of arteries and veins. At the same time, COVID-19 lung histopathology has…
Abstract Number: 0442 • ACR Convergence 2020
Disparities in CoronaViridae Infection Are Readily Apparent in Rheumatology Patients Despite Use of Hydroxychloquine And/or Methotrexate
Maria Antonelli¹ and Nora Singer², ¹MHMC/CWRU, Cleveland, OH, ²The MetroHealth System, Case Western Reserve University School of Medicine, Cleveland, OH
Background/Purpose: In the initial months of the SARS CoV2/COVID19 pandemic, broad use of off-label therapy with hydroxychloroquine (HCQ) was prescribed to reduce CoV2-related morbidity and…
Abstract Number: 0445 • ACR Convergence 2020
Dual-Energy CT in Gout Patients: Do All Color-Coded Lesions Actually Represent Monosodium Urate Crystals?
Sara Christiansen¹, Felix Müller², Mikkel Østergaard³, Ole Slot¹, Jakob Møller², Henrik Børgesen², Kasper Gosvig² and Lene Terslev⁴, ¹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup., Glostrup, Denmark, ²Department of Radiology, Herlev and Gentofte Hospital, Herlev, Denmark, ³Rigshospitalet, University of Copenhagen, Copenhagen, Denmark, ⁴Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup., Copenhagen, Denmark
Background/Purpose: Dual-Energy CT (DECT) can acknowledge differences in tissue compositions and can color-code tissues with specific features including monosodium urate (MSU) crystals. However, when evaluating…
Abstract Number: 0446 • ACR Convergence 2020
Novel Ultrasound Image Acquisition Protocol and Scoring System for the Pediatric Ankle
Patricia Vega-Fernandez¹, Deirdre De Ranieri², Edward Oberle³, Hulya Bukulmez⁴, Clara Lin⁵, Susan Shenoi⁶, Akaluck Thatayatikom⁷, Leandra Woolnough⁸, Kathleen Jo Corbin⁹, Heather Benham¹⁰, Emily Brunner¹¹, Michael Henrickson¹, Laura Ballenger³, Sara Haro¹², Christina Schutt¹³, Jean-Philippe Proulx-Gauthier¹⁴, Ginger Janow¹⁵, Mekibib Altaye¹⁶, Amy Cassedy¹, Johannes Roth¹⁷ and Tracy Ting¹, ¹Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Lurie Children's Hospital, Chicago, IL, ³Nationwide Children's Hospital, Columbus, OH, ⁴MetroHealth Medical Center, Case Western Reserve, Pepper Pike, OH, ⁵Children's Hospital Colorado, Aurora, CO, ⁶Seattle Childrens Hospital, seattle, WA, ⁷Department of Pediatrics, University of Florida, Gainesville, FL, ⁸University of Florida, Gainesville, FL, ⁹Yale University School of Medicine, Woodbridge, CT, ¹⁰Texas Scottish RIte Hospital, North Richland Hills, TX, ¹¹Geisinger, Bloomsburg, PA, ¹²UCSF, San Francisco, CA, ¹³University of Pittsburgh Medical Center, Pittsburgh, PA, ¹⁴CHU de Quebec - Universite Laval, Quebec, Canada, ¹⁵Joseph M. Sanzari Children's Hospital at Hackensack Meridian Health, Hackensack, NJ, ¹⁶Cincinnati Children's Hospital Medical Center, Cincinnati, ¹⁷University of Ottawa, Ottawa, ON, Canada
Background/Purpose: The clinical decision-making process in pediatric arthritis lacks an objective, reliable bedside imaging tool. Although increasingly used for children, there is a need for…
Abstract Number: 0441 • ACR Convergence 2020
Use of an Integrated Care Management Program to Uncover and Address Social Determinants of Health for Individuals with Lupus
Kreager Taber¹, Jessica Williams¹, Weixing Huang², Katherine McLaughlin¹, Christine Vogeli³, Rebecca Cunningham¹, Lisa Wichmann¹ and Candace Feldman⁴, ¹Brigham and Women's Hospital, Boston, MA, ²Division of Rheumatology, Inflammation, and Immunity; Brigham and Women’s Hospital and Harvard Medical School, Boston, ³Massachusetts General Hospital, Boston, MA, ⁴Brigham and Women's Hospital, Boston
Background/Purpose: The burden of systemic lupus erythematosus (SLE) falls disproportionately on racial/ethnic minorities and individuals of lower socioeconomic status who often receive fragmented, inconsistent care.…

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