ACR Meeting Abstracts

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  • Abstract Number: 0413 • ACR Convergence 2020

    Coronavirus Infection and Vasculitis: Identifying Associations Mining the Biomedical Literature

    Alicia Rodriguez Pla1 and Rodrigo Cartin-Ceba2, 1Rheumatology. Mayo Clinic Arizona, Scottsdale, 2Pulmonary. Mayo Clinic Arizona, Scottsdale, AZ

    Background/Purpose: Based on recent publications suggesting an association between COVID-19 and vascular inflammation, our aim was to explore new associations between coronavirus infections and vasculitis…
  • Abstract Number: 0415 • ACR Convergence 2020

    Characteristics of Arthritis in Adult IgA Vasculitis

    Alojzija Hocevar1, Vesna Jurcic2, Matija Tomsic1 and Ziga Rotar1, 1University Medical Center Ljubljana, LJUBLJANA, Slovenia, 2Institute of Pathology, Medical Faculty, University of Ljubljana, LJUBLJANA, Slovenia

    Background/Purpose: Arthritis is one of the main clinical features in IgA vasculitis (IgAV). In children, joint involvement represents the second most common manifestation with the…
  • Abstract Number: 0420 • ACR Convergence 2020

    Prospective Analysis of the Prevalence of Giant Cell Arteritis in Consecutive Newly Diagnosed Patients with Polymyalgia Rheumatica

    Lara Burg1, Peter Brossart2, Charlotte Behning3 and Valentin Schaefer4, 1Clinic for Internal Medicine III, Department of Oncology, Haematology, Rheumatology and Clinical Immunology, University Hospital Bonn, Germany, Bonn, Nordrhein-Westfalen, Germany, 2Clinic for Internal Medicine III, Department of Oncology, Hematology and Rheumatology, University Hospital Bonn, Germany, Bonn, Nordrhein-Westfalen, Germany, 3Institute for Medical Biometry, Informatics and Epidemiology, University Hospital Bonn, Germany, Bonn, Nordrhein-Westfalen, Germany, 4Clinic of Internal Medicine III, Department of Oncology, Hematology and Rheumatology, University Hospital Bonn, Germany, Bonn, Nordrhein-Westfalen, Germany

    Background/Purpose: Giant cell arteritis (GCA) is the most common form of systemic vasculitis affecting people aged 50 years and older.1 Although it is known, that…
  • Abstract Number: 0423 • ACR Convergence 2020

    Defining Ear Chondritis: Data from 685 Patients with Relapsing Polychondritis

    Marcela Ferrada1, Nathalie Costedoat-Chalumeau2, Guillaume Moulis3, Nancy Linn4, Emily Rose1 and Peter C. Grayson5, 1Systemic Autoimmunity Branch, Vasculitis Translational Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 2APHP, Université de Paris, Paris, France, 3Toulouse University hospital, Toulouse, France, 4Relapsing Polychondritis Foundation, Palos Verdes Estates, CA, 5Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Bethesda, MD

    Background/Purpose: Ear chondritis is often considered the pathognomonic feature of relapsing polychondritis (RP).  Although painful redness and swelling of the pinna and a resultant cauliflower…
  • Abstract Number: 0428 • ACR Convergence 2020

    Enrichment of Clinical Trial Recruitment Using Advanced Molecular Imaging in Takayasu’s Arteritis

    Kaitlin Quinn1, Mark Ahlman2, Emily Rose3, Peter Merkel4 and Peter C. Grayson5, 1Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Bethesda, 2National Institutes of Health, Clinical Center, Radiology and Imaging Sciences, Bethesda, MD, 3Systemic Autoimmunity Branch, Vasculitis Translational Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 4University of Pennsylvania, Philadelphia, PA, 5Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Bethesda, MD

    Background/Purpose: Definitions of disease activity are not standardized in Takayasu’s arteritis (TAK), which can lead to difficulty in determining whether a patient should be enrolled…
  • Abstract Number: 0432 • ACR Convergence 2020

    The Effect on Renal Function of the Complement C5a Receptor Inhibitor Avacopan in ANCA-Associated Vasculitis

    Peter Merkel1, Pirow Bekker2, Huibin Yue2, Catherine Kelleher2, Thomas Schall2 and David Jayne3, 1University of Pennsylvania, Philadelphia, PA, 2ChemoCentryx, Mountain View, CA, 3Department of Medicine, Vasculitis and Lupus Research Group, University of Cambridge, Cambridge, UK, Cambridge, United Kingdom

    Background/Purpose: Avacopan, a novel, orally-administered selective antagonist of C5aR, was recently evaluated in a pivotal Phase 3 randomized clinical trial where its use in patients…
  • Abstract Number: 0411 • ACR Convergence 2020

    Serial Vessel Wall Enhancement Change on High-Resolution MRI Vessel Wall Imaging in Primary Central Nervous System Vasculitis

    Takashi Shimoyama1, Ken Uchino2, Leonard Calabrese2 and Rula Hajj-ali2, 1Nippon Medical School, Nippon, Japan, 2Cleveland Clinic, Cleveland, OH

    Background/Purpose: High-resolution vessel wall imaging (HR-VWI) is emerging as a tool of notable utility in the diagnosis of central nervous system vasculitis (CNS-V). However, little…
  • Abstract Number: 0422 • ACR Convergence 2020

    Frailty and Health-Related Quality of Life in Patients with Polymyalgia Rheumatica

    Sebastian Sattui1, Deanna Jannat-Khah2, Lindsay Lally1, Sarah Lieber1, Lisa Mandl1 and Robert Spiera3, 1Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, New York City, NY, 3Division of Rheumatology, Hospital for Special Surgery, New York, New York, USA, New York, NY

    Background/Purpose: Frailty is a syndrome characterized by an increased vulnerability to stressors. Frailty and pre-frailty have been reported in 10% and 44%of community dwelling elderly,…
  • Abstract Number: 0424 • ACR Convergence 2020

    Anti-Collagen II Antibodies in Patients with Relapsing Polychondritis

    Kristina Wells1, Marcela Ferrada2, Emily Rose2, Keith Sikora3, Wendy Goodspeed2, Kaitlin Quinn4 and Peter C. Grayson5, 1Systemic Autoimmunity Branch, Vasculitis Translational Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, 2Systemic Autoimmunity Branch, Vasculitis Translational Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 3National Institutes of Health Clinical Center, Bethesda, MD, 4Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Washington, DC, 5Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Bethesda, MD

    Background/Purpose: Relapsing polychondritis (RP) is a highly heterogenous systemic inflammatory disorder that affects many organ systems, in particular, cartilaginous structures. Clinical presentations in RP are…
  • Abstract Number: 0419 • ACR Convergence 2020

    Survival and Prevalent Comorbidities in Polymyalgia Rheumatica

    Carl Turesson1, Ankita Sharma2, Charlotta Fors2, Jan Åke Nilsson3, Aladdin Mohammad4 and Ulf Bergström2, 1Rheumatology, Department of Clinical Sciences Malmö, Lund University, Department of Rheumatology, Skåne University Hospital, Malmö, Sweden., Malmö, Sweden, 2Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden, 3Rheumatology, Department of Clinical Sciences, Malmö, Lund University. Department of Rheumatology, Skåne University Hospital, Malmö and Lund, Sweden, Malmö, Sweden, 4Lund University, Lund, Sweden. Department of Medicine, Vasculitis and Lupus Research Group, University of Cambridge, Cambridge, UK, Lund, Sweden

    Background/Purpose: There is limited information on mortality in patients with polymyalgia rheumatica (PMR), and on prevalent comorbidity at the time of diagnosis of PMR. The…
  • Abstract Number: 0414 • ACR Convergence 2020

    Clinical Characteristics of an Internet-Based Cohort of Participants with a Self-Reported Diagnosis of Cryoglobulinemic Vasculitis or IgA Vasculitis

    Jason Springer1, Tanaz Kermani2, Dianne Shaw3, Kalen Young4, Cristina Burroughs5 and Peter Merkel6, 1University of Kansas Medical Center, Overland Park, KS, 2David Geffen School of Medicine / University of California, Los Angeles, CA, 3Vasculitis Foundation, North Carolina, 4Vasculitis Foundation, Kansas City, 5University of South Florida, Tampa, 6University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Cyroglobulinemic vasculitis (CV) and IgA vasculitis are forms of small-vessel vasculitis characterized by immune complex deposition. The purpose of this study was to a)…
  • Abstract Number: 0427 • ACR Convergence 2020

    Validation of Physician Global Assessment as an Outcome Measure in Relapsing Polychondritis

    Emily Rose1, Marcela Ferrada1, Kaitlin Quinn2, Wendy Goodspeed1, Laurent Arnaud3 and Peter C. Grayson4, 1Systemic Autoimmunity Branch, Vasculitis Translational Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, BETHESDA, MD, 2Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Washington, DC, 3Department of rheumatology, University Hospitals of Strasbourg and French National Reference Center for Rare Auto-immune diseases, Strasbourg, Alsace, France, 4Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Bethesda, MD

    Background/Purpose: Relapsing polychondritis (RP) is a rare systemic inflammatory disorder of cartilage that lacks validated disease activity measures. Physician global assessment (PhGA) is a measure…
  • Abstract Number: 0430 • ACR Convergence 2020

    Outcomes of Coronavirus Disease 2019 Infection Among Patients Living with Rheumatic Diseases: A Matched Cohort Study from a US Multi-Center Research Network

    Kristin D'Silva1, April Jorge1, Na Lu2, Yuqing Zhang3, Zachary Wallace4 and Hyon Choi5, 1Massachusetts General Hospital, Boston, MA, 2Arthritis Research Canada, Vancouver, BC, Canada, 3Massachusetts General Hospital, Quincy, MA, 4Massachusetts General Hospital, Newton, MA, 5Massachusetts General Hospital, Department of Medicine, Division of Rheumatology, Lexington, MA

    Background/Purpose: Whether patients living with systemic autoimmune rheumatic diseases (SARDs) suffer from more severe complications of Coronavirus Disease 2019 (COVID-19) infection remains unknown.Methods: We conducted…
  • Abstract Number: 0431 • ACR Convergence 2020

    Hydroxychloroquine Use Was Not Associated with QTc Length in a Large Cohort of SLE and RA Patients

    Elizabeth Park1, Jon Giles2, Thania Perez-Recio1, Paloma Pina3, Christopher Depender1, Joan Bathon1 and Laura Geraldino-Pardilla4, 1Division of Rheumatology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, 2Columbia University, New York, NY, 3Cardiac Electrophysiology, Northwestern Medicine, Chicago, IL, 4Division of Rheumatology, Columbia University Vagelos College of Physicians and Surgeons, New York

    Background/Purpose: Hydroxychloroquine (HCQ) is a cornerstone therapy for systemic lupus erythematosus (SLE), and is used as monotherapy and combined with other DMARDs in rheumatoid arthritis…
  • Abstract Number: 0426 • ACR Convergence 2020

    T-Cell Receptor (TCR) Sequencing Reveals Decreased Diversity and Clonotypic Expansion of T-cells in Relapsing Polychondritis (RP)

    Emily Rominger1, Sufia Bakshi2, Emily Rose3, Marcela Ferrada3, Peter C. Grayson4, Robert Colbert5 and Keith Sikora6, 1Systemic Autoimmunity Branch, Vasculitis Translational Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, 2National Institutes of Health, Bethesda, MD, 3Systemic Autoimmunity Branch, Vasculitis Translational Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, 4Systemic Autoimmunity Branch, National Institutes of Health, NIAMS, Bethesda, MD, 5Pediatric Clinical Trials Unit and Office of Clinical Director, NIAMS, NIH, Bethesda, MD, 6National Institutes of Health Clinical Center, Bethesda, MD

    Background/Purpose: Relapsing polychondritis (RP) is a rare, systemic inflammatory disease characterized by recurrent inflammation of cartilaginous structures, including the nose/ears, joints, and trachea. The etiology of…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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