ACR Meeting Abstracts

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  • Abstract Number: 1438 • ACR Convergence 2022

    The Ratio Between Biological and Glucocorticoid Use in Different Countries Worldwide: Results from the METEOR Registry

    Isabell Nevins1, CF Allaart1, David Vega Morales2, Lai Ling Winchow3, Arvind Chopra4, Ana Maria Rodrigues5, Tom Huizinga1, Maarten Boers6 and Sytske Anne Bergstra7, 1Leiden University Medical Center, Leiden, Netherlands, 2Autonomous University of Nuevo León, Monterrey, Mexico, 3Chris hani baragwanath academic hospital, Johannesburg, South Africa, 4Center for Rheumatic Diseases, Pune, Maharashtra, India, 5Reuma.pt, Sociedade Portuguesa de Reumatologia, Lisbon, Portugal, 6Amsterdam UMC, Vrije Universiteit, Amsterdam, Netherlands, 7LUMC, Leiden, Netherlands

    Background/Purpose: Previous studies have demonstrated differing bDMARD prescription rates between countries, which seems to be amongst others related to a country's socioeconomic status. In contrast,…
  • Abstract Number: 1435 • ACR Convergence 2022

    Effectiveness of Combination Therapy with Tocilizumab and Low-Dose Prednisolone as an Induction Therapy in Biologics-Naïve Patients with Rheumatoid Arthritis: A Prospective, Randomized, Controlled, Open-Label, Multicenter Study

    Kazuhiro Yokota1, Hayato Nagasawa2, Yuji Akiyama3 and Toshihide Mimura4, 1Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Iruma Saitama, 2Nagasawa Clinic, Kawagoe, Japan, 3Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Iruma Saitama, Japan, 4Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Saitama, Japan

    Background/Purpose: Efficacy and safety of tocilizumab (TCZ) in the treatment of rheumatoid arthritis (RA) has demonstrated in randomized controlled trials. However, the clinical response to…
  • Abstract Number: 1441 • ACR Convergence 2022

    Prevalence of Secondary Connective Tissue Diseases and Autoantibodies Among Racial and Ethnic Groups in Systemic Lupus Erythematosus Patients in the Manhattan Lupus Surveillance Program

    Brendan Denvir1, Philip Carlucci2, Jill Buyon3, H Michael Belmont4, Kelly Corbitt1, Sara Sahl5, Jane Salmon6, Anca Askanase7, Joan Bathon7, Laura Geraldino-Pardilla8, Yousaf Ali9, Ellen M. Ginzler10, Chaim Putterman11, Caroline Gordon12, Hilary Parton13 and Peter Izmirly3, 1New York University, New York, NY, 2New York University School of Medicine, New York, NY, 3NYU Grossman School of Medicine, New York, NY, 4NYU School of Medicine, New York, NY, 5Harbor-University of California Medical Center, Los Angeles, CA, 6Hospital for Special Surgery, New York, NY, 7Columbia University Medical Center, New York, NY, 8Columbia University, New York, NY, 9Icahn School of Medicine at Mount Sinai, New York, NY, 10SUNY Downstate Health Sciences University, Department of Medicine, Brooklyn, NY, 11Albert Einstein College of Medicine, Bronx, NY, 12Rheumatology Research Group, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom, 13New York City Department of Health and Mental Hygiene, New York, NY

    Background/Purpose: Epidemiologic data of secondary connective tissue disease and autoantibody profiles among patients with systemic lupus erythematosus (SLE) remains limited for racial/ethnic populations in the…
  • Abstract Number: 1431 • ACR Convergence 2022

    Impact of Tofacitinib on Fracture Risk in Rheumatoid Arthritis

    Karen E Hansen1, Mahta Mortezavi2, Edward Nagy3, Cunshan Wang4, Carol A Connell4, Zaher Radi5, Heather J Litman6, Giovanni Adami7 and Maurizio Rossini7, 1Rheumatology Division, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 2Pfizer Inc, New York, NY, 3Pfizer Ltd, Tadworth, United Kingdom, 4Pfizer Inc, Groton, CT, 5Pfizer Inc., Cambridge, MA, 6CorEvitas, LLC, Waltham, MA, 7Rheumatology Unit, Department of Medicine, University of Verona, Verona, Italy

    Background/Purpose: Preclinical data suggest that tofacitinib stimulates osteoblast function and would have a protective effect on bone health and fracture risk in RA.1 We report…
  • Abstract Number: 1413 • ACR Convergence 2022

    Early Muscle Involvement in Patients with Rheumatoid Arthritis: A Large-Scale Cross-Sectional Study

    Jie Pan1, Yao-Wei Zou1, Ying-Ying Zhu2, Jian-da Ma3, Jian-Zi Lin3, Tao Wu1, Ze-Hong Yang2, Xue-Pei Zhang1, Qian Zhang1, Hu-Wei Zheng1, Xiao-Ling He4, Wan-Mei Cheng4 and Lie Dai3, 1Sun Yat-Sen University, Guangzhou, China, 2Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China, 3Department of Rheumatology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China, 4Shanghai Healthare Co. Ltd, Shang hai, China

    Background/Purpose: Muscle loss is common in long-standing rheumatoid arthritis (RA) patients. However, less is known about this unfavorable alteration of body composition (BC) and its…
  • Abstract Number: 1445 • ACR Convergence 2022

    Gastrointestinal Manifestations in Systemic Lupus Erythematosus Are Associated with High Disease Activity and Mortality: A Nationwide Cohort Study from India

    Pankti Mehta1, Akansha Srivastava2, Amita Aggarwal2, Liza Rajasekhar3, Vineetha Shobha4, Chengappa Kavadichanda5, ASHISH JACOB MATHEW6, Parasar Ghosh7, Bidyut Das8, Avinash Jain9, Ranjan Gupta10 and Manish Rathi11, 1King George's Medical University, Lucknow, India, 2Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, 3Nizam's Institute of Medical Sciences, Madhapur, India, 4St. John’s Medical College Hospital, Bangalore, India, 5JIPMER, Pondicherry, Puducherry, India, 6Christian Medical College, Vellore, Vellore, India, 7Govt of West Bengal, Kolkata, India, Kolkata, West Bengal, India, 8SCB medical college, Cuttack, India, 9SMS Medical College, Lucknow, India, 10All India Institute of Medical Sciences, New Delhi, India, 11PGIMER Chandigarh, Chandigarh, India

    Background/Purpose: Gastrointestinal (GI) manifestations of Systemic Lupus Erythematosus (SLE) although rare are often severe. These are difficult to directly attribute to SLE as they can…
  • Abstract Number: 1449 • ACR Convergence 2022

    Incidence and Risk Factors for Active Tuberculosis in Patients with Systemic Lupus Erythematosus: A Multicenter Prospective Cohort Study

    Lifan Zhang1, xiaoqing zou2, Lantian Xie3, Jianghao Liu3, zhengrong yang4, qifei cao4, Chunlei Li5, Xiaochuan Sun5, Fengchun ZHANG6, Yan Zhao7, Xiaofeng Zeng8 and Xiaoqing Liu1, 1Division of Infectious Diseases, Department of Internal medicine, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College; Clinical Epidemiology Unit, Peking Union Medical College, International Clinical Epidemiology Network; Center for Tuberculosis Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 2Division of Infectious Diseases, Department of Internal medicine, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College; School of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 3Peking Union Medical College Hospital, Peking Union Medical College, Beijing, China, 4Division of Infectious Diseases, Department of Internal medicine, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 5Department of Internal medicine, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 6Peking Union Medical College Hospital, Beijing, China, 7Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Key Laboratory of Rheumatology & Clinical Immunology, Ministry of Education, Beijing, China, 8Department of Rheumatology, Peking Union Medical College Hospital (PUMCH), Chinese Academy of Medical Sciences National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Beijing, China

    Background/Purpose: The burden of tuberculosis (TB) and systemic lupus erythematosus (SLE) in China are both the second largest in the world. Patients with SLE are…
  • Abstract Number: 1451 • ACR Convergence 2022

    Delayed Sleep Phase Syndrome Characterizes Circadian Disorder in Patients with Active SLE

    Christina Stankey1, Philip Chu2, Alicia Hinze3, Lily McMorrow1, Alia El-Qunni1, Deepali Sen1, Seth Eisen1, Yo-El Ju1 and Alfred Kim1, 1Washington University School of Medicine, St. Louis, MO, 2Duke University Hospital, Raleigh, NC, 3Mayo Clinic - Rochester, MN, Rochester, MN

    Background/Purpose: Poor sleep quality is a common complaint of patients with SLE. Although chronic sleep disruption is known to drive circadian rhythm disorders, the effects…
  • Abstract Number: 1444 • ACR Convergence 2022

    Patients with Lupus Pericarditis Have the Impact on the Poor Survival Outcome: A Retrospective Cohort Study

    YENFU CHEN and Yao-Fan Fang, Chang Gung Memorial Hospital, Taoyuan, Taiwan

    Background/Purpose: Patients with systemic lupus erythematosus (SLE) had a higher risk of pericarditis, which could be life-threating, but there has been no research focusing on…
  • Abstract Number: 1452 • ACR Convergence 2022

    Patterns of Outpatient and Acute Care Use Among Patients with SLE on Long-Term Moderate to High Dose Glucocorticoid Medication: A 1 Year Retrospective Analysis

    James Sullivan1 and Emily Littlejohn2, 1Cleveland Clinic Lerner College of Medicine, Cleveland Heights, OH, 2Cleveland Clinic, Cleveland, OH

    Background/Purpose: Long-term glucocorticoid use can lead to adverse outcomes independent of SLE disease activity. Identifying factors associated with long-term glucocorticoids is an important step towards…
  • Abstract Number: 1433 • ACR Convergence 2022

    A 48-week Analysis of a Pan-EU Real-world Study of SB5 Biosimilar Following Transition from Reference Adalimumab in Patients with Rheumatoid Arthritis, Axial Spondyloarthritis or Psoriatic Arthritis

    Ulf Müller-Ladner1, Karl Gaffney2, Deepak Jadon3, Marco Matucci-Cerinic4, Eugenio Chamizo Carmona5 and Janet Addison6, 1JLU Campus KK, Bad Nauheim, Germany, 2Norfolk and Norwich University Hospital NHS Trust, Norfolk, United Kingdom, 3Cambridge University, Cambridge, United Kingdom, 4University of Florence, Florence, Italy, 5Hospital de Mérida, Mérida, Spain, 6Biogen Idec Ltd, Maidenhead, United Kingdom

    Background/Purpose: SB5, a biosimilar to reference adalimumab (ADL), received marketing authorisation in 2017 (EU) and 2019 (US) based on pre-clinical and clinical phase I and…
  • Abstract Number: 1457 • ACR Convergence 2022

    Baseline Characteristics of a Longitudinal, Multinational, Multiethnic Study of Lupus Patients, with or Without Lupus Nephritis

    Romina Nieto1, Rosana Quintana2, eduardo Borba3, Lucia Hernandez4, Diana Fernandez-Avila5, Laura Maurelli6, Paul Alba7, Florencia Bordon8, Fernando Arizpe9, Guillermo Berbotta10, Rosa Serrano-Morales11, Maria Constanza Bertolaccini12, Eduardo Kerzberg13, Maria Angeles Gargiulo14, Anabella Rodriguez15, Vitalina Barbosa16, Andres gasparin17, Fernando Cavalcanti18, Laissa Alves Alvino19, Luciana Parente Costa Seguro20, Lucas Victoria de Oliveira Martins21, oscar Niera22, Loreto Massardo23, Gustavo Aroca Martinez24, Ivana Nieto Aristizabal25, Paul Mendez Patarroyo26, Antonio iglesias Gamarra24, Andres Zuniga Vera27, Olga-Lidia Vera-Lastra28, Mario Perez Cristobal29, Eduardo Martin-Nares30, Luis M Amezcua-Guerra31, Yelitza Gonzalez-Bello32, Octavio Gonzalez Enriquez33, Dionico Galarzo-Delgado34, Carolina Vazquez35, Marcelo barrios36, Magaly Alba Linares37, Cristina Reategui38, Ana Quiroz-Alva39, Teresandris Polanco Mora40, Carina Pizzarossa41, Martin Rebella42, Maria Crespo43, Alvaro Danza44, Eloisa Silva Dutra de Oliveira Bonfa45, Graciela Alarcón46, Federico Zazzetti47, Ashley Orillion48, Guillermo Pons-Estel49 and Urbano Sbarigia50 1GO-CREAR, Rosario, Santa Fe, Argentina, 2Grupo Oroño - Centro Regional de Enfermedades Autoinmunes y Reumáticas (GO-CREAR), Rosario, Santa Fe, Argentina, 3Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil, 4Instituto de Investigaciones Teóricas y Aplicadas. Facultad de Ciencias Económicas y Estadistica. Universidad Nacional de Rosario, Rosario, Argentina, 5Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 6Hospital Italiano de Córdoba, Córdoba, Argentina, 7Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 8Hospital Privado Universitario de Córdoba, Cordoba, Argentina, 9Hospital HIGA San Martín, San Martín, Argentina, 10Sanatorio Británico, Rosario, Argentina, 11Sanatorio Parque. Centro de Enfermedades Autoinmunes y Reumáticas del Grupo Oroño, Rosario, Argentina, 12Hospital Padilla, San Miguel de Tucuman, Argentina, 13Hospital General de Agudos Dr. Ramos Mejia, Buenos Aires, Argentina, 14Instituto de Investigaciones Médicas Alfredo Lanari, Buenos Aires, Argentina, 15CEMIC, Galvan, Argentina, 16Universidade Federal de Goiás, Goiana, Brazil, 17Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil, 18Universidad Federal de Pernambuco, Recife, Brazil, 19Hospital Universitario Pedro Ernesto, UERJ, Rio de Janiero, Brazil, 20Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 21Universidad Federal São Paulo, São Paulo, Brazil, 22Hospital del Salvador, Providencia, Chile, 23Universidad San Sebastián, Santiago de Chile, Chile, 24Clínica de la Costa Ltda., Barranquilla, Colombia, 25Fundación Valle del Lili, Calí, Colombia, 26Fundación Santa Fe, Bogotá, Colombia, 27Hospital Luis Vernaza, Guayaquil, Ecuador, 28Centro Médico La Raza, Ciudad de México, Mexico, 29Centro Médico Nacional Siglo XXI, Ciudad de México, Mexico, 30Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, Mexico, 31Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de México, Mexico, 32Centro de Estudios de investigación Básica y Clínica S.C, Jalisco, Mexico, 33Hospital Central Dr. Ignacio Morones Prieto, San Luis, Mexico, 34Hospital Universitario "Dr. José Eleuterio Gonzalez", Monterrey, Mexico, 35Hospital de Clínicas I, Montevideo, Uruguay, 36Hospital de Clínicas II, Montevideo, Uruguay, 37Hospital Nacional Edgardo Rebagliatti Martins, Lima, Peru, 38Hospital Nacional Guillermo Almenara Irigoyen. EsSalud, Lima, Peru, 39Hospital Cayetano Heredia, San Martín de Porres District, Peru, 40Hospital Docente Padre Billini, Santo Domingo, Dominican Republic, 41Clínica Médica C, Hospital de Clínicas, UDELAR, Montevideo, Uruguay, 42Departamento de Medicina, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay, 43Hospital Señor del Milagro, Salta, Argentina, 44Grupo de Investigacion de EAIS y Reumatológicas, A Coruña, Spain, 45Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, 46The University of Alabama at Birmingham, Oakland, 47Janssen Medical Affairs Global Services, LLC, Buenos Aires, Argentina, 48Janssen, Horsham, PA, 49CREAR, Rosario, Argentina, 50Johnson & Johnson, Beerse, Belgium

    Background/Purpose: Clinically evident kidney disease eventually occurs in up to one-half of SLE patients. The aim of this study is to describe sociodemographic, clinical, serological…
  • Abstract Number: 1460 • ACR Convergence 2022

    Neuropsychiatric Lupus in Late and Early Onset Systemic Lupus Erythematosus Patients: A Systemic Review and Meta-analysis

    Omer Pamuk1, Saja Ali2 and Sarfaraz Hasni2, 1NIH/NIAMS, Bethesda, MD, 2NIAMS/NIH, Bethesda, MD

    Background/Purpose: The diagnosis of neuropsychiatric lupus (NPSLE) is challenging due to its variegated presentation, absence of diagnostic biomarkers and radiological imaging. The NPSLE is further…
  • Abstract Number: 1463 • ACR Convergence 2022

    Short- and Long-Term Progression of Kidney Involvement in Systemic Lupus Erythematosus Patients with Low-Grade Proteinuria

    Shudan Wang1, Allan Spielman2, Mindy Ginsberg2, Michelle Petri3, Brad Rovin4, Jill Buyon5 and Anna Broder6, 1Montefiore Medical Center / Albert Einstein College of Medicine, New York, NY, 2Albert Einstein College of Medicine, Bronx, NY, 3Johns Hopkins University School of Medicine, Division of Rheumatology, Baltimore, MD, 4The Ohio State University, Columbus, OH, 5NYU Grossman School of Medicine, New York, NY, 6Hackensack University Medical Center, Hackensack, NJ

    Background/Purpose: Lupus nephritis remains a common cause of morbidity and mortality in systemic lupus erythematosus (SLE). Current guidelines recommend performing a kidney biopsy at urine…
  • Abstract Number: 1403 • ACR Convergence 2022

    Herpes Zoster in Rheumatoid Arthritis: Prospective Single University Center Study

    Lucia Cristina Dominguez Casas1, Mª Paz Rodriguez Cundin2, Trinidad Dierssen Sotos3, Nuria Vegas Revenga4, Alfonso Corrales5, Miguel Ángel González-Gay6 and Ricardo Blanco7, 1Hospital Universtario San Agustin, Oviedo, Spain, 2Hospital Universitario Marqués de Valdecilla, Santander, Spain, 3Universidad de Cantabria, Santander, Spain, 4Hospital Galdakao- Usansolo, Galdakao, Spain, 5Research Group on Genetic Epidemiology and Atherosclerosis in Systemic Diseases and in Metabolic Bone Diseases of the Musculoskeletal System, IDIVAL; and Department of Rheumatology, Hospital Universitario Marqués de Valdecilla, Santander, Spain, 6Department of Medicine and Psychiatry, Universidad de Cantabria; Rheumatology Division, Hospital Universitario Marqués de Valdecilla; Research group on genetic epidemiology and atherosclerosis in systemic diseases and in metabolic diseases of the musculoskeletal system, IDIVAL, Santander, Spain. Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, 7Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain

    Background/Purpose: Patients with Rheumatoid arthritis (RA) have an increased risk of infections due to the disease itself, and/or immunosuppressive therapy. The risk of herpes zoster…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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