ACR Meeting Abstracts

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  • Abstract Number: 1181 • ACR Convergence 2022

    Hippo Pathway Effectors Promote and Maintain Myofibroblast Differentiation and Endothelial-to-mesenchymal Transition in Systemic Sclerosis

    Feiyang Ma1, Pei-Suen Tsou1, Grace Hile1, John Varga1, J. Michelle Kahlenberg1, Allison Billi1, Johann Gudjonsson1 and Dinesh Khanna2, 1University of Michigan, Ann Arbor, MI, 2Division of Rheumatology, Department of Internal Medicine, Scleroderma Program, University of Michigan, Ann Arbor, MI

    Background/Purpose: Systemic sclerosis (SSc) is a devastating autoimmune disease characterized by excessive production and accumulation of extracellular matrix molecules leading to fibrosis of skin and…
  • Abstract Number: 1321 • ACR Convergence 2022

    Systemic Inflammatory-based Scores and Bone Turnover Ratio as Novel Diagnostic Tools for Chronic Nonbacterial Osteomyelitis (CNO) of the Sternocostoclavicular Region in Adults

    Anne Leerling, Juliette Faber, Natasha Appelman-Dijkstra, Olaf Dekkers and Elizabeth Winter, Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands

    Background/Purpose: Chronic non-bacterial osteomyelitis (CNO) in adults exhibits as sterile osteitis and consequent disrupted bone metabolism favoring bone formation of the sternocostoclavicular region (SCCH). Diagnosis…
  • Abstract Number: 1317 • ACR Convergence 2022

    The Epidemiology of Old versus Young Males Referred for BMD Assessment

    Muhammed Aqib Khan1, Rabie Hamad1, Hamzah Amin1 and Marwan Bukhari2, 1Royal Lancaster Infirmary, Lancaster, United Kingdom, 2University Hospitals of Morecambe Bay NHS Trust, Lancaster, United Kingdom

    Background/Purpose: Data on osteoporosis in men are scarce. The World Health Organisation's (WHO) definition of a T-score less than 2.5 has only been described for…
  • Abstract Number: 1307 • ACR Convergence 2022

    Effect of Romosozumab in Postmenopausal Women with Knee Osteoarthritis: Results from the FRAME Clinical Trial

    Nancy Lane1, Donald Betah2, Cynthia Deignan2, Mary Oates2, Zhenxun Wang2, Jen Timoshenko3, Aliya Khan4 and Neil Binkley5, 1University of California Davis, Hillsborough, CA, 2Amgen, Inc., Thousand Oaks, CA, 3UCB Pharma, Slough, United Kingdom, 4McMaster University, Oakville, ON, Canada, 5University of Wisconsin, Madison, WI

    Background/Purpose: Osteoarthritis (OA) and osteoporosis (OP) often occur concomitantly in the elderly. The relationship between OA and OP is complex, with increased fracture risk reported…
  • Abstract Number: 1291 • ACR Convergence 2022

    Development and Pilot Implementation of a Predictive Model to Identify Visits Appropriate for Telehealth

    david leverenz1, Mary Solomon1, Nicoleta Economau-Zavlanos1, Bhargav Srinivas Adagarla2, Theresa Coles1, Isaac Smith3, Robert Overton1, Catherine Howe3, Jayanth Doss4, Ricardo Henao1 and Megan Clowse4, 1Duke University School of Medicine, Durham, NC, 2Duke Clinical Research Institute, Durham, NC, 3Duke University Hospital, Durham, NC, 4Duke University, Durham, NC

    Background/Purpose: Since January 2021, providers in our practice have used the Encounter Appropriateness Score for You (EASY) to document their perception of the appropriateness of…
  • Abstract Number: 1075 • ACR Convergence 2022

    Efficacy of Mepolizumab in Patients with Eosinophilic Granulomatosis with Polyangiitis and a Vasculitic Phenotype

    Benjamin Terrier1, David Jayne2, Bernhard Hellmich3, Jane Bentley4, Jonathan Steinfeld5, Steven Yancey6, Namhee Kwon7, Praveen Akuthota8, Paneez Khoury9, Lee Baylis10 and Michael Wechsler11, 1National Referral Center for Rare Systemic Autoimmune Diseases, Cochin Hospital, Paris, France, 2University of Cambridge, Cambridge, United Kingdom, 3Klinik für Innere Medizin, Rheumatologie & Immunologie, Medius Kliniken, Universität Tübingen, Plochingen, Germany, 4Clinical Statistics, GlaxoSmithKline, Brentford, United Kingdom, 5Clinical Sciences, Respiratory, GSK (affiliation at time of research), Philadelphia, PA, 6Respiratory Therapeutic Area, GSK (affiliation at the time of research), Research Triangle Park, NC, 7Clinical Sciences, Respiratory, GSK, Brentford, United Kingdom, 8Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of California, San Diego, CA, 9Human Eosinophil Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 10Global Medical Affairs, GlaxoSmithKline, Durham, NC, 11Department of Medicine, National Jewish Health, Denver, CO

    Background/Purpose: Patients with eosinophilic granulomatosis with polyangiitis (EGPA) can have vasculitic or eosinophilic phenotypes. The MIRRA study demonstrated that patients with EGPA spent more time…
  • Abstract Number: 1312 • ACR Convergence 2022

    Cost-Effectiveness of Sequential Treatment with Abaloparatide Followed by Alendronate in US Men at High Risk of Fracture

    Mickael Hiligsmann1, Stuart Silverman2, Andrea J Singer3, Leny Pearman4, jake Mathew4, Yamei Wang4, John Caminis4 and Jean-Yves Reginster5, 1Maastricht University, Maastricht, Netherlands, 2Cedar-Sinai Medical Center and UCLA School of Medicine, Los Angeles, CA, 3MedStar Georgetown University Hospital, Washington, DC, 4Radius Health, Inc., Waltham, MA, 5University of Liège, Liège, Belgium

    Background/Purpose: Previous cost-effectiveness analyses in postmenopausal women (PmW) with osteoporosis (OP) demonstrated that sequential treatment with abaloparatide (ABL) followed by alendronate (ALN) resulted in lower…
  • Abstract Number: 1323 • ACR Convergence 2022

    Secondary Prevention of Vertebral Fractures Sustained Efficacy over Time

    JOSE ELOY OLLER RODRIGUEZ1, Elena Grau García2, Samuel Leal Rodriguez3, Laura Mas Sanchez2, Pablo Francisco Muñoz Martínez4, Carmen Riesco Bárcena5, Anderson Huaylla Quispe6, Cristobal Pavez Perales2, Francisco Miguel Ortiz Sanjuan7, José Ivorra Cortés2, Inés Cánovas Olmos2, Luis González Puig8, Isabel Martínez-Cordellat2, Carmen Nájera Herranz7, Rosa Negueroles Albuixech2, Elvira Vicens Bernabeu7, Alba Torrat Novés5, Daniel Ramos Castro2 and José andrés Román ivorra3, 1Hospital Universitario de La Fe, València, Spain, 2Rheumatology Department. Hospital Universitario y Politécnico La Fe, València, Spain, 3Hospital Universitari i Politécnic La Fe, València, Spain, 4Hospital Universitario y Politécnico La Fe, València, Spain, 5Rheumatology Department. Hospital Universitario y Politécnico La Fe, València, 6Medicina, València, Spain, 7Hospital Universitario de La Fe, València, 8Rheumatology Department. Hospital Universitario y Politécnico La Fe, Torrente, Valencia, Spain

    Background/Purpose: Vertebral fractures entail a notorious social and health problem, and their presence is the greatest risk factor for the appearance of a new vertebral…
  • Abstract Number: 1322 • ACR Convergence 2022

    Follow up of Incidentally Noted Vertebral Compression Fractures

    Jason Yang1, Alexia Hwang1, Megan Brochu2, Krista Sabina2, Meridith Malysz2, Bruce Weinstein3 and Jonathan Cheah1, 1UMass Chan Medical School, Worcester, MA, 2UMass Memorial Health, Worcester, MA, 3UMass Memorial Health, UMass Chan Medical School, Worcester, MA

    Background/Purpose: Vertebral compression fractures (VCFs) in general represent a clinical diagnosis of osteoporosis, predisposing to an increased risk of additional fractures. However, a significant number…
  • Abstract Number: 1315 • ACR Convergence 2022

    Building Stronger Bones: Optimizing Osteoporosis Screening at a Primary Care Clinic

    Rebecca Pietro1, Shu Min Lao1 and Geeta Varghese2, 1Mount Sinai Morningside West, New York, NY, 2Ryan Chelsea Clinton Clinic, New York, NY

    Background/Purpose: Osteoporosis is a silent disease characterized by low bone mass and deterioration of bone quality, affecting 25% of women.1 The United States Preventive Services…
  • Abstract Number: 1330 • ACR Convergence 2022

    Impact of COVID-19 Severity on Physical Function, Mobility, Falls and Fractures Among Older Patients After Hospitalization: A Longitudinal Study

    Clara Wong1, Diego Cabrera2, Mary Geda3, Andrew Cohen3, Lauren Ferrante3, Alexandra Hajduk3 and Evelyn Hsieh2, 1Yale School of Public Health, New Haven, CT, 2Section of Rheumatology, Allergy and Immunology, Yale School of Medicine, New Haven, CT, 3Yale School of Medicine, New Haven, CT

    Background/Purpose: No longitudinal studies have examined the impact of COVID-19 or COVID-19 severity on physical function and disability outcomes among older adults. Multiple factors, including…
  • Abstract Number: 1339 • ACR Convergence 2022

    Impact of the COVID-19 Pandemic on Patients with Rheumatoid Arthritis: Data from the Ontario Best Practices Research Initiative (OBRI)

    Matthew Wong-Pack1, Elliot Hepworth2, Mohammad Movahedi3, Bindee Kuriya1, Janet Pope4, Edward Keystone5, Carter Thorne6, VANDANA AHLUWALIA7, Angela Cesta8, Carol Mously8, Claire Bombardier1, Arthur Lau9 and Sibel Aydin10, 1University of Toronto, Toronto, ON, Canada, 2University of Ottawa, Ottawa, ON, Canada, 3Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada, 4University of Western Ontario, London, ON, Canada, 5Keystone Consulting Enterprises Inc., Toronto, ON, Canada, 6Southlake Regional Health Centre, Newmarket, ON, Canada, 7William Osler Health System, Brampton, ON, Canada, 8University Health Network, Toronto, ON, Canada, 9McMaster University, Hamilton, ON, Canada, 10University of Ottawa, Rheumatology, Ottawa, Canada, Ottawa, ON, Canada

    Background/Purpose: The COVID-19 Pandemic created challenges for patients with rheumatoid arthritis (RA), including accessing the health care system, transition to unplanned virtual care, reduction in…
  • Abstract Number: 1340 • ACR Convergence 2022

    Nutrition-Related Behaviors and Beliefs – A Survey of Rheumatic Disease Patients

    Sandy Lee1, Leanna Wise2 and Stavros Savvas3, 1University of Southern California, Walnut, CA, 2LAC+USC/Keck Medicine of USC, Pasadena, CA, 3Keck Medicine of USC, Glendale, CA

    Background/Purpose: Diet and nutrition have long been of interest to both patients and providers in the treatment of chronic disease. The literature is relatively sparse…
  • Abstract Number: 1335 • ACR Convergence 2022

    Artificial Intelligence–enabled Sentiment Analysis of Public Attitude Toward Pregnancy in Lupus Social Media Group

    Gopisree Peringeth1 and Milena Vukelic2, 1Jacobi Medical Center/Albert Einstein College of Medicine, New York, NY, 2Albert Einstein College of Medicine, New York, NY

    Background/Purpose: Lupus commonly affects women of reproductive age whose pregnancies are associated with higher rates of complications and fetal loss. There is a knowledge gap…
  • Abstract Number: 1341 • ACR Convergence 2022

    Clinical Outcomes of COVID-19 Vaccination and Booster in Patients with Autoimmune Inflammatory Rheumatic Diseases

    Silera Holguin Balbuena, Anna Radisic, Sarah Goodman, Shreya Gor, Beatrice Wood, Alexander Shahin, Kelara Samuel, Rahul Mhaskar and John Carter, University of South Florida, Tampa, FL

    Background/Purpose: The spread of COVID-19 began in December 2019 and quickly escalated into a global pandemic resulting in millions of deaths. Many factors are associated…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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