ACR Meeting Abstracts

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  • Abstract Number: 1912 • ACR Convergence 2022

    Associations of Nociceptive Dysfunction with Physical Activity in Knee Osteoarthritis: The Multicenter Osteoarthritis Study

    Deepak Kumar1, Na Wang2, Kaveh Torabian1, Kosaku Aoyagi3, Joshua Stefanik4, Laura Frey-Law5, Lisa Carlesso6, Jeffrey Hausdorff7, Eran Gazit7, Neil Segal8, Cora E. Lewis9, Michael Nevitt10 and Tuhina Neogi2, 1Boston University, Boston, MA, 2Boston University School of Medicine, Boston, MA, 3Boston University, Quincy, MA, 4Northeastern University, Boston, MA, 5University of Iowa, Iowa City, IA, 6McMaster University, Hamilton, ON, Canada, 7Tel Aviv Suarasky Medical Center, Tel Aviv, Israel, 8University of Kansas, Kansas City, KS, 9University of Alabama at Birmingham, Birmingham, AL, 10University of California San Francisco, Orinda, CA

    Background/Purpose: Individuals with chronic pain due to knee osteoarthritis (OA) are insufficiently physically active and increasing physical activity is the first line recommendation for management…
  • Abstract Number: 1913 • ACR Convergence 2022

    The Association of Radiographic Chondrocalcinosis with Localized Structural Outcomes in Knee OA: The Multicenter Osteoarthritis Study

    Jean Liew1, Ali Guermazi2, Mohamed Jarraya3, Na Wang1, David Felson2, Cora E. Lewis4, Michael Nevitt5, James Torner6, John A. Lynch7 and Tuhina Neogi1, 1Boston University School of Medicine, Boston, MA, 2Boston University, Boston, MA, 3Massachusetts General Hospital, Boston, MA, 4University of Alabama at Birmingham, Birmingham, AL, 5University of California at San Francisco, Orinda, CA, 6University of Iowa, Iowa City, IA, 7UCSF, San Francisco, CA

    Background/Purpose: Intra-articular (IA) mineralization due to calcium crystal deposition may contribute to OA pathology through inflammation, release of pro-catabolic factors, or altered cartilage biomechanical properties.…
  • Abstract Number: 1903 • ACR Convergence 2022

    Does Pain Sensitization by Pressure Pain Thresholds and Temporal Summation Predict Persistent Pain in Persons with Hand OA?

    Pernille Steen Pettersen1, Tuhina Neogi2, Elisabeth Mulrooney1, Marthe Gløersen1, Hilde Berner Hammer3 and Ida K. Haugen1, 1Center for treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway, Oslo, Norway, 2Boston University School of Medicine, Boston, MA, 3Diakonhjemmet hospital, Jar, Norway

    Background/Purpose: Pain sensitization is part of the complexity of osteoarthritis (OA) pain. We aimed to examine whether pain sensitization by pressure pain thresholds (PPT) and…
  • Abstract Number: 1911 • ACR Convergence 2022

    Baseline Bone Curvature a Biomarker for the Prediction of Knee Osteoarthritis Cartilage Volume Loss at One-Year. Use of Machine Learning

    Johanne Martel-Pelletier1, Hossein Bonakdari1, Jean-Pierre Pelletier1 and François Abram2, 1Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montréal, QC, Canada, 2ArthroLab Inc., Montréal, QC, Canada

    Background/Purpose: The hallmark of osteoarthritis is the loss of cartilage. At present, we cannot discriminate, early during the osteoarthritis process, patients for whom cartilage will…
  • Abstract Number: 1924 • ACR Convergence 2022

    Reading the Waves: Identifying Distinct Phenotypes of Multisystem Inflammatory Syndrome in Children During the 2020-2021 COVID-19 Pandemic

    Thomas Renson1, Nils Forkert1, Kimberly Amador1, Paivi Miettunen1, Simon Parsons1, Muhammed Dhalla1, Nicole Johnson2, Nadia Luca2, Heinrike Schmeling1, Rebeka Stevenson1, Marinka Twilt1, Lorraine Hamiwka1 and Susanne Benseler1, 1Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, 2University of Calgary, Calgary, AB, Canada

    Background/Purpose: The COVID-19-associated multisystem inflammatory syndrome in children (MIS-C) is characterized by Kawasaki disease (KD)-like mucocutaneous features. The clinical course is often unpredictable. The goals…
  • Abstract Number: 1918 • ACR Convergence 2022

    Neurobiological Mechanisms of a Remote-Delivered Mind-body Intervention for Knee Osteoarthritis

    Jian Kong1 and Chenchen Wang2, 1Massachusetts General Hospital, Boston, MA, 2Tufts Medical Center, Boston, MA

    Background/Purpose: As a recommended intervention for knee Osteoarthritis (OA) according to current guidelines, Tai Chi, a multi-dimensional exercise has exhibited clinically significant improvements in knee…
  • Abstract Number: 1920 • ACR Convergence 2022

    Gait and Physical Activity Predictors of Knee Replacement: A Machine Learning Analysis in the Multicenter Osteoarthritis Study

    Kerry Costello1, David Felson1, S. Reza Jafarzadeh2, Neil Segal3, Cora E. Lewis4, Michael Nevitt5, Vijaya Kolachalama2 and Deepak Kumar1, 1Boston University, Boston, MA, 2Boston University School of Medicine, Boston, MA, 3University of Kansas, Kansas City, KS, 4University of Alabama at Birmingham, Birmingham, AL, 5University of California at San Francisco, Orinda, CA

    Background/Purpose: Rates of knee replacement (KR) due to knee osteoarthritis (OA) are rising exponentially and currently no interventions prevent KR. Gait and physical activity are…
  • Abstract Number: 1916 • ACR Convergence 2022

    Defining Early-stage Knee Osteoarthritis: A Scoping Review

    Jean Liew1, Lauren King2, Armaghan Mahmoudian3, Qiuke Wang4, Tuhina Neogi1 and Gillian Hawker2, 1Boston University School of Medicine, Boston, MA, 2University of Toronto, Toronto, ON, Canada, 3Lund University, Lund, Sweden, 4Erasmus Medical Center, Rotterdam, Netherlands

    Background/Purpose: Clinical trials of disease-modifying agents in knee osteoarthritis (OA) have largely failed to date. Identifying individuals with knee OA at an earlier stage in…
  • Abstract Number: 1927 • ACR Convergence 2022

    Patient and Parent Perceptions of an Established Rheumatology Transition Clinic for Adolescents and Young Adults

    Rebecca Overbury1, Devin Eddington2, Katherine Sward2, John Bohnsack1, CJ Inman1, Sara Stern1, Karen James1, Erin Treemarcki1 and Aimee Hersh1, 1University of Utah, Salt Lake City, UT, 2University of Utah, Salt Lake City

    Background/Purpose: The Adult Center for Childhood Onset Rheumatic Disease (ACCORD) is a clinical and research center for the health care transition (HCT) of adolescent and…
  • Abstract Number: 1929 • ACR Convergence 2022

    Outcomes and Safety of Anakinra for the Treatment of Multisystem Inflammatory Syndrome in Children

    Dizon Brian1, Christopher Redmond2, Emily Gotschlich3, Sangeeta Sule4, Tova Ronis4, Kathleen Vazzana5, Matthew Sherman6, Rachael Connor7, Abigail Bosk4, Niti Dham4, Ashraf Harahsheh4, Elizabeth Wells4, Roberta DeBiasi4 and Hemalatha Srinivasalu4, 1National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, 2National Institutes of Health, Rockville, MD, 3FDA, Washington, DC, 4Children's National Hospital, Washington, DC, 5Arnold Palmer Hospital for Children, Orlando, FL, 6Muscle Disease Unit, Laboratory of Muscle Stem Cells and Gene Regulation, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH); Children’s National Hospital, Washington, DC, 7Children's National Medical Center, Washington, DC

    Background/Purpose: Multisystem inflammatory syndrome in children (MIS-C) is a clinical entity distinct from primary COVID-19 infection that resembles Kawasaki disease (KD) and toxic shock syndrome.…
  • Abstract Number: 1926 • ACR Convergence 2022

    Analysis of New Patient Referrals to a Large Pediatric Rheumatology Clinic

    Daniel Reiff, Melissa Mannion, Emily Smitherman, Matthew Stoll, Peter Weiser and Randy Cron, University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Large pediatric rheumatology centers receive hundreds of yearly referrals with a wide variety of complaints and diagnoses. The amount of referrals received can lead…
  • Abstract Number: 1928 • ACR Convergence 2022

    Idiopathic Pulmonary Capillaritis Within the Spectrum of Pediatric Diffuse Alveolar Hemorrhage

    Angela Chun1, Tiphanie vogel1, Andrea Ramirez1, Marietta De Guzman2, Eyal Muscal1 and Manuel Silva-Carmona3, 1Baylor College of Medicine, Houston, TX, 2Baylor College of Medicine/ Texas Children's Hospital, Houston, TX, 3Baylor College of Medicine, Texas Children's Hospital, Houston, TX

    Background/Purpose: Diffuse alveolar hemorrhage (DAH) is a life-threatening syndrome with bleeding from the pulmonary microvasculature. It is classified as pulmonary capillaritis if histology shows neutrophilic…
  • Abstract Number: 1420 • ACR Convergence 2022

    Outcomes in Patients with Rheumatoid Arthritis Initiating Monotherapy with Etanercept, Adalimumab, or Janus Kinase Inhibitors

    Dimitrios Pappas1, Jacqueline O'Brien2, Mike Kelleman2, Lin Guo2, Ying Shan2, Joshua Baker3, Greg Kricorian4, Scott Stryker5 and David Collier6, 1Corrona Research Foundation; CorEvitas, LLC, Albany, NY, 2CorEvitas, LLC, Waltham, MA, 3University of Pennsylvania and Corporal Michael J. Crescenz VA Medical Center, Philadelphia, 4Amgen, Inc., Thousand Oaks, CA, 5Amgen Inc., San Francisco, CA, 6Amgen Inc., Simi Valley, CA

    Background/Purpose: Biologic/targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) often are used as monotherapy in rheumatoid arthritis (RA). However, little is known about the comparative effectiveness of…
  • Abstract Number: 1870 • ACR Convergence 2022

    Clinical Outcomes Following Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Vaccination in Patients with Anti-Melanoma Differentiation Associated Gene 5 (MDA5) Antibody Positive Dermatomyositis

    Richard Seto1, Sangmee Bae1 and Christina Charles-Schoeman2, 1University of California Los Angeles, Los Angeles, CA, 2Division of Rheumatology, University of California, Los Angeles, Santa Monica, CA

    Background/Purpose: Patients with dermatomyositis (DM) and antibodies (ab) to melanoma differentiation associated gene 5 (MDA5) share similar clinical characteristics to patients infected with the severe…
  • Abstract Number: 1820 • ACR Convergence 2022

    Targeted Plasma Lipidomics Distinguishes Patients with Gout and Hyperuricemia from Controls

    Blanka Stiburkova1, Kateřina Pavelcová1, Jana Bohatá1, Karel Pavelka2, Lenka Hasíková1, Jakub Závada1, Aleš Kvasnička3, Dana Dobešová3 and David Friedecký3, 1Institute of Rheumatology, Prague, Czech Republic, 2Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Praha, Czech Republic, 3Palacky University Olomouc, Olomouc, Czech Republic

    Background/Purpose: Gout is the most common type of inflammatory arthritis, characterised by chronic deposition of uric acid crystals in the joints, affecting approx. 1-2% of…
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Embargo Policy

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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