ACR Meeting Abstracts

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  • Abstract Number: 1564 • ACR Convergence 2022

    Anti-TNF versus Anti-IL6 Receptor Antagonist Therapy in Severe Ocular Involvement in Behçet’s Disease

    Nuria Barroso-García1, Belén Atienza-Mateo2, Ivan Ferraz Amaro3, Diana Prieto-Peña2, Ana De Vicente-Delmás4, Ricardo Blanco5 and Miguel Ángel González-Gay6, 1Hospital Universitario Puerta del Mar, Cádiz, Spain, Cádiz, Spain, 2Research Group on Genetic Epidemiology and Atherosclerosis in Systemic Diseases and in Metabolic Bone Diseases of the Musculoskeletal System, IDIVAL; and Department of Rheumatology, Hospital Universitario Marqués de Valdecilla, Santander, Spain, 3Division of Rheumatology. Hospital Universitario de Canarias. Spain., Santa Cruz de Tenerife, Spain, 4Hospital General Santa María del Puerto, Cádiz, Spain, 5Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 6Department of Medicine and Psychiatry, Universidad de Cantabria; Rheumatology Division, Hospital Universitario Marqués de Valdecilla; Research group on genetic epidemiology and atherosclerosis in systemic diseases and in metabolic diseases of the musculoskeletal system, IDIVAL, Santander, Spain. Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

    Background/Purpose: To evaluate the efficacy of anti-TNF or anti-IL6 treatment in severe and refractory ocular involvement in patients with refractory cystoid macular edema (CME) due…
  • Abstract Number: 1554 • ACR Convergence 2022

    Serum Biomarkers in Association with Clinical and Vascular Disease Activity in Takayasu’s Arteritis

    Cameron Rankin1, Peter Grayson2, Bates Gribbons3, Kaitlin Quinn4, Christopher Redmond5 and Wanxia Tsai1, 1NIAMS/NIH, Bethesda, MD, 2National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, 3McGovern Medical School, Colleyville, TX, 4National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Washington, DC, 5National Institutes of Health, Rockville, MD

    Background/Purpose: 18FDG-PET imaging can be used to directly assess vascular inflammation; however, limited access to this technology has restricted widespread adoption of this modality in…
  • Abstract Number: 1562 • ACR Convergence 2022

    Validation of Behçet’s Disease Overall Damage Index (BODI) for Retrospective Studies and a Proposal for Modification

    Yeliz Yagiz Ozogul1, Yesim Ozguler2, Didar Ucar3, Ugur Uygunoglu4, Zekayi Kutlubay5, Vedat Hamuryudan6 and gulen Hatemi7, 1Istanbul University-Cerrahpaşa, Cerrahpaşa Medical School, Department of Internal Medicine, Istanbul, Turkey, 2Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, New York, NY, 3Istanbul University-Cerrahpaşa, Cerrahpaşa Medical School, Department of Ophthalmology, Istanbul, Turkey, 4Istanbul University-Cerrahpaşa, Cerrahpaşa Medical School, Department of Neurology, Istanbul, Turkey, 5Istanbul University-Cerrahpaşa, Cerrahpaşa Medical School, Department of Dermatology, Istanbul, Turkey, 6Istanbul University-Cerrahpaşa, Cerrahpaşa Medical School, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 7Istanbul University-Cerrahpaşa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey

    Background/Purpose: Damage accrual in Behçet syndrome (BS) may progress over the years and an index that can be scored using retrospective data may be useful…
  • Abstract Number: 1575 • ACR Convergence 2022

    Characteristics of an Internet-Based, International Cohort of Patients with a Self-Reported Diagnosis of Urticarial Vasculitis

    Jason Springer1, Tanaz Kermani2, Dianne Shaw3, Kalen Larson4, Cristina Burroughs5 and Peter Merkel6, 1Vanderbilt University Medical Center, Nashville, TN, 2University of California Los Angeles, Los Angeles, CA, 3Vasculitis Foundation, Chapel Hill, NC, 4Vasculitis Foundation, Kansas City, MO, 5University of South Florida, Tampa, FL, 6University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Urticarial vasculitis is a markedly rare disease, with an annual incidence of < 1 per million. Hypocomplementemia is associated with systemic features and a…
  • Abstract Number: 1569 • ACR Convergence 2022

    Lung Involvement in VEXAS Syndrome

    Marta Casal Moura1, Misbah Baqir1, Yasmeen Tandon2, Matthew J. Samec3, Kaaren K. Reichard4, Abhishek Mangaonkar5, Ronald S. Go5, Kenneth J. Warrington6, Mrinal Patnaik7, Matthew J. Koster6 and Jay H. Ryu1, 1Mayo Clinic, Division of Pulmonary and Critical Care Medicine, Department of Medicine, Rochester, USA, Rochester, 2Mayo Clinic, Radiology, Rochester, USA, Rochester, 3Mayo Clinic, Division of Rheumatology, Department of Medicine, Rochester, USA, Rochester, 4Mayo Clinic, Department of Laboratory Medicine and Pathology, Rochester, USA, Rochester, 5Mayo Clinic, Division of Hematology, Department of Medicine, Rochester, USA, Rochester, 6Mayo Clinic, ROCHESTER, MN, 7Mayo Clinic, Division of Hematology, Department of Medicine, Rochester, United States of America, Rochester

    Background/Purpose: Vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome is a recently identified disorder caused by somatic mutations in the UBA1 gene of myeloid cells.…
  • Abstract Number: 1571 • ACR Convergence 2022

    Coronary Arteritis and Periarteritis Secondary to IgG4-related Disease in a Large, Single-center Cohort

    Guy Katz1, sandeep hedgire1, James Stone2, Sebastian Perez-Espina1, Ana Fernandes1, Cory Perugino1, Zachary Wallace1 and John Stone3, 1Massachusetts General Hospital, Boston, MA, 2Massachusetts General Hospital, Reading, MA, 3Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA

    Background/Purpose: IgG4-related disease (IgG4-RD) is a systemic autoimmune fibroinflammatory disease capable of affecting most organ systems. Large-vessel vasculitis is a well-described manifestation of the disease.…
  • Abstract Number: 1567 • ACR Convergence 2022

    Refractory Macular Edema Due to Behçet’s Disease. Multicenter Comparative Study of Adalimumab and Certolizumab Pegol

    José Luis Martín-Varillas1, Lara Sánchez-Bilbao2, Vanesa Calvo Río3, Alf Adán4, Inés Hernanz Rodríguez4, Miguel Cordero Coma5, David Díaz Valle6, Patricia Fanlo7, Juan Ramón de Dios8, A. Garcia-Aparicio9, Sergio Rodriguez Montero10, Vega Jovani Casano11, Patricia Moya Alvarado12, eva Peña Sainz-Pardo13, José Luis Hernández2 and Ricardo Blanco14, 1Hospital de Laredo, Laredo, Cantabria, Spain, 2Hospital Universitario Marqués de Valdecilla, Santander, Spain, 3Valdecilla Hospital, Santander, Spain, 4H. Clinic, Barcelona, Spain, 5Hospital de León, León, Spain, 6Hospital Clínico San Carlos, Madrid, Spain, 7Complejo Hospitalario de Navarra, Navarra, Spain, 8Hospital de Araba, Araba, Spain, 9Hospital Universitario de Toledo, Toledo, Spain, 10Virgen de Valme University Hospital, Sevilla, Spain, 11National Health system, Alicante, Spain, 12Hospital Parc Tauli, Barcelona, Spain, 13Hospital Universitario 12 de Octubre, Madrid, Spain, 14Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain

    Background/Purpose: Cystoid Macular Edema (CME) is the leading cause of blindness in non-infectious uveitis. Behçet's disease (BD) is one of the diseases most frequently associated…
  • Abstract Number: 1578 • ACR Convergence 2022

    Long-term Cardiovascular Disease and Mortality Following Kawasaki Disease in Childhood: A Systematic Review and Meta-analysis

    Francis Lao1, Cal Robinson2, Megan Schlorff1, Joycelynn Ewusie3, KAREN BEATTIE1 and Michelle Batthish1, 1McMaster University, Hamilton, ON, Canada, 2The Hospital for Sick Children, Hamilton, ON, Canada, 3St Joseph's Healthcare Hamilton, Hamilton, ON, Canada

    Background/Purpose: Kawasaki Disease (KD) is a common childhood vasculitis. Coronary artery aneurysms (CAAs) develop in approximately 25% of untreated KD patients. However, there is limited…
  • Abstract Number: 1580 • ACR Convergence 2022

    Poor Serum Urate Control Is a Driver of Excess Cardiovascular Risk in Patients with Gout

    Tate Johnson1, Lindsay Helget2, Harlan Sayles2, Punyasha Roul3, James O'Dell2, Ted Mikuls4 and Bryant England2, 1University of Nebraska Medical Center, Elkhorn, NE, 2University of Nebraska Medical Center, Omaha, NE, 3UNMC, Omaha, NE, 4Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Gout patients suffer from an increased burden of cardiovascular disease (CVD). It remains unclear whether this risk is related to an excess of CVD…
  • Abstract Number: 1577 • ACR Convergence 2022

    Impact of Cutaneous Vasculitis on Health-Related Quality-of-Life

    Sarah Mann1, Aamir Hussain2, Anisha Dua3, Angelina Patrone4, Kalen Larson5, Peter Merkel6 and Robert Micheletti7, 1Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 2Department of Dermatology, Georgetown University, Washington, DC, 3Northwestern University, Chicago, IL, 4Patient Partner, Philadelphia, PA, 5Vasculitis Foundation, Kansas City, MO, 6University of Pennsylvania, Philadelphia, PA, 7Departments of Dermatology and Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Cutaneous manifestations of vasculitis can cause pruritus, pain, and ulceration, and their psychosocial impacts may be significant. However, the quality-of-life (QoL) impact of skin…
  • Abstract Number: 1579 • ACR Convergence 2022

    The TICOG Study: Tight Control of Gout – A Randomized, Controlled Trial of Targeted versus Conventional Treatment for Gout Including Ultrasonography

    Sarah Black, Natalie McKee, Jonathan McKnight, Annmarie McShane, Adrian Pendleton, Taggart Alister and Gary Wright, Musgrave Park Hospital, Belfast Health and Social Care Trust, Belfast, Northern Ireland, United Kingdom

    Background/Purpose: Gout is a common inflammatory arthritis triggered by deposition of monosodium urate crystals in joints, bone and soft tissues, with a prevalence of 1-4%…
  • Abstract Number: 1074 • ACR Convergence 2022

    Safety and Efficacy of Dupilumab in Patients with Relapsing and/or Refractory Eosinophilic Granulomatosis with Polyangiitis

    Berengere Molina1, Maria Letizia Urban2, Roberto Padoan3, Pavel Novikov4, Camille Taillé5, Marco Caminati6, Christine Christides7, nicolas schleinitz8, Laura Moi9, Vincent Cottin10, bertrand godeau11, Laurence Bouillet12, Paolo Fraticelli13, Ann Knight14, Jan Walter Schroeder15, Sylvain Marchand-Adam16, Helder Gil17, Elena Gelain18, Giacomo Emmi2 and Benjamin Terrier19, 1Department of Internal Medicine, Cochin Hospital, Paris, France, 2Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy, 3University of Padova, Padova, Italy, 4Tareev’s Clinic, Sechenov First Moscow State Medical University, Moscow, Russia, 5Pulmonology department, Bichat Hospital, Paris, Ile-de-France, France, 6Verona University Hospital, University of Verona, Verona, Italy, 7Avignon hospital, Avignon, France, 8Aix Marseille university, AP-HM, Marseille, France, 9Centre hospitalier universitaire vaudois, Lausanne, Lausanne, Switzerland, 10Coordinating Reference Center for Rare Pulmonary Diseases, Louis Pradel Hospital, University of Lyon, INRAE, Lyon, France, 11Department of Internal Medicine, National Referral Center for Adult's Immune Cytopenias, Mondor Hospital, Créteil, France, 12Grenoble University Hospital, Grenoble, France, 13Department of Internal Medicine, Ospedali Riuniti di Ancona, Ancona, Italy, 14Akademiska sjukhuset, Uppsala, Sweden, 15ASST GOM Niguarda, Milano, Italy, 16Tours University Hospital, Tours, France, 17Besancon University Hospital, Besançon, France, 18Meyer Children’s University Hospital of Firenze, Florence, Italy, 19National Referral Center for Rare Systemic Autoimmune Diseases, Cochin Hospital, Paris, France

    Background/Purpose: Eosinophilic granulomatosis with polyangiitis (EGPA) is an ANCA-associated vasculitides characterized by asthma, blood and tissue eosinophilia and systemic manifestations. Glucocorticosteroids (GCs)-dependent asthma and/or disabling…
  • Abstract Number: 1521 • ACR Convergence 2022

    Long-term Follow-Up of Participants of the Phase II Study That Evaluated Subcutaneous Abatacept vs. Placebo in Diffuse Cutaneous Systemic Sclerosis (ASSET Trial)

    Nadine Sarsam1, Sindhu R. Johnson2, Lorinda Chung3, Suzanne Kafaja4, Janet Pope5, Robyn Domsic6, Maureen Mayes7, Nora Sandorfi8, Virginia Steen9, Flavia Castelino10, Faye Hant11, Suiyuan Huang1 and Dinesh Khanna12, 1University of Michigan, Ann Arbor, MI, 2Division of Rheumatology, Department of Medicine, Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western and Mount Sinai Hospitals; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada, 3Stanford University, Stanford, CA, 4UCLA Department of Medicine, Division of Rheumatology, Los Angeles, CA, 5University of Western Ontario, London, ON, Canada, 6University of Pittsburgh, Pittsburgh, PA, 7Division of Rheumatology and Clinical Immunogenetics, University of Texas McGovern Medical School, Houston, TX, 8University of Pennsylvania, Philadelphia, PA, 9Georgetown University School of Medicine, Washington, DC, 10Massachusetts General Hospital, Boston, MA, 11Medical University of South Carolina, Charleston, SC, 12Division of Rheumatology, Department of Internal Medicine, Scleroderma Program, University of Michigan, Ann Arbor, MI

    Background/Purpose: Abatacept (ABA) is a cytotoxic T-lymphocyte-associated molecule-4 immunoglobulin fusion protein which has been shown to induce regression of dermal fibrosis in patients with systemic…
  • Abstract Number: 1471 • ACR Convergence 2022

    Trends and Predictors of Hospitalizations Due to Acute Myocardial Infarction in Systemic Lupus Erythematosus Patients

    Izza Bazigh1, Uzair Khan2, Achint Patel3, Aaparna Singh3, Neha Ghalib3, Ghazi Farman4, Salman Muddassir3, Farrukh Zaidi5, Sami Mughni3 and Adam Grunbaum6, 1HCA Florida Oak Hill Hospital, Spring Hill, FL, 2HCA Healthcare Florida / USF Morsani College of Medicine GME Consortium / Oak Hill Hospital, Odessa, FL, 3HCA Healthcare Florida / USF Morsani College of Medicine GME Consortium / Oak Hill Hospital, Spring Hill, FL, 4Rehman Medical College, Spring Hill, FL, 5HCA Healthcare Florida / USF Morsani College of Medicine GME Consortium / Oak Hill Hospital, Port Richey, FL, 6Gulf Coast Rheumatology, Trinity, FL

    Background/Purpose: Cardiovascular events occur more frequently and with earlier onset in patients with Systemic Lupus Erythematosus (SLE) compared with healthy individuals. Several studies have concluded…
  • Abstract Number: 1327 • ACR Convergence 2022

    Immune Cell Subsets and Risk of Incident Hip Fracture in Older Adults: The Cardiovascular Health Study

    Rachel Elam1, Petra Buzkova2, Joseph Delaney3, Howard Fink4, Joshua Barzilay5, Laura Carbone1, Rick Saha1, John Robbins6, Kenneth Mukamal7, Rodrigo Valderrabano8, Bruce Psaty2, Russell Tracy9, Nels Olson9, Sally Huber10, Margaret Doyle9, Alan Landay11 and Jane Cauley12, 1Augusta University, Augusta, GA, 2University of Washington, Seattle, WA, 3University of Manitoba, Winnipeg, MB, Canada, 4University of Minnesota, Minneapolis, MN, 5Kaiser Permanente, Atlanta, GA, 6UC Davis, Davis, CA, 7Beth Israel Deaconess Medical Center, Boston, MA, 8Brigham and Women's Hospital, Boston, MA, 9University of Vermont, Burlington, VT, 10University of Vermont, Burlingon, VT, 11Rush University Medical Center, Chicago, IL, 12University of Pittsburgh, PIttsburgh, PA

    Background/Purpose: Cell-mediated immunity may play a role in osteoporosis development. Fracture is the major consequence of osteoporosis. Thus, cell-mediated immunity may impact fracture risk. We…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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