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  • Abstract Number: 0095 • ACR Convergence 2025

    Effect of JAK Inhibitors on Osteoblast Differentiation

    Toshihiro Tanioka1 and Takeo Isozaki2, 1Graduate School of Pharmacy, Showa Medical University, Shinagawa-ku,Tokyo, Tokyo, Japan, 2Graduate School of Pharmacy, Showa Medical University, Tokyo, Tokyo, Japan

    Background/Purpose: Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and joint destruction. Among the therapeutic strategies available, Janus kinase (JAK) inhibitors have…
  • Abstract Number: 0139 • ACR Convergence 2025

    When One Isn’t Enough: Does Adding IgM Worsen the Antiphospholipid Syndrome Phenotype?

    Santiago Dans Caballero1, Massimo Radin2, Chary López pedrera3, MARIA ANGELES AGUIRRE ZAMORANO4, Christian Merlo-Ruiz5, Ismael Sanchez-Pareja4, Irene Cecchi6 and Savino Sciascia7, 1Reina Sofia University Hospital, Lebrija, Andalucia, Spain, 2University of Turin, Turin, Turin, Italy, 3Rheumatology service/Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ Reina Sofia University Hospital/ University of Cordoba, Spain, Cordoba, Spain, 4Rheumatology service/Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ Reina Sofia University Hospital/ University of Cordoba, Spain, Córdoba, Spain, 5Rheumatology service/Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ Reina Sofia University Hospital/ University of Cordoba, Spain, Córdoba, Spain, 6University of Turin, Turin, Piemonte, Italy, 7University of Turin, Torino, Italy

    Background/Purpose: Antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by the persistent presence of antiphospholipid antibodies (aPL) along with clinical manifestations such as venous…
  • Abstract Number: 0207 • ACR Convergence 2025

    The Feasibility and Clinical Effects of Anti-Inflammatory Diet Intervention In Patients Diagnosed With Long COVID (Post-Acute Sequelae of SARS CoV-2, PASC)

    Suzi Hong1, Marcos Monteon2, Kathleen Bundy3, Chloe Delgado Ramirez3, Phoebe Senowitz3, Monica Guma4, Nina Acebo5, Chris Pruitt6, Tanya Shekhtman3, Shahrokh Golshan7 and Susan Lee8, 1Herbert Wertheim School of Public Health and Human Longevity Science UCSD; Department of Psychiatry UCSD, San Diego, 2University of California, San Diego, San Diego, 3Department of Family Medicine, Center for Integrative Health, Krupp Endowment Fund, UCSD, La Jolla, 4University of California San Diego, San Diego, CA, 5University of California, San Diego, La Jolla, 6Herbert Wertheim School of Public Health and Human Longevity Science, UCSD, La Jolla, 7Department of Pyschiatry, UCSD, La Jolla, 8Department of Medicine, University of California, San Diego, La Jolla, CA

    Background/Purpose: There have been over 777 million cases of acute COVID-19 infections worldwide as of April 2025. Although many patients recover, an estimated 10-30% of…
  • Abstract Number: 0177 • ACR Convergence 2025

    Artificial intelligence in adult and paediatric rheumatology practice and research: pilot results from an international survey

    Ana Isabel Rebollo-Gimenez1, Saverio La bella2, Krystel Aouad3, Latika Gupta4, Davide Cangelosi5, Thomas Högle6, Johannes Knitza7, Nicolino Ruperto8, Vincenzo Venerito9, Abdellah El Maghraoui10, Alessandra Alongi11, Wilson bautista molano12, Deniz Bayraktar13, Thomas Davergne14, Dzifa Dey15, Ihsane Hmamouchi16, Alison Hoens17, Linda Li17, Angela Migowa18, Erin Treemarcki19, Nelly Ziade20, Tue Kragstrup21 and Diego Benavent22, 1Department of Rheumatology, Gregorio Marañon University Hospital, Gregorio Marañon Health Research Institute, Madrid, Spain, 2UOC Reumatologia e Malattie Autoinfiammatorie, IRCCS Istituto Giannina Gaslini, Genoa, Italy, 3Department of Rheumatology, Saint George Hospital University Medical Center, Beirut, Lebanon, 4School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham; Royal Wolverhampton NHS Trust; Centre for Musculoskeletal Research, School of Biological Sciences, The University of Manchester, Manchester; Francis Crick Institute, London, Birmingham, UK, United Kingdom, 5Unità di Bioinformatica Clinica, Direzione Scientifica, IRCCS Istituto Giannina Gaslini, Genoa, Italy, 6Department of Rheumatology, University Hospital Lausanne (CHUV) and University of Lausanne, Lausanne, Switzerland, 7Institute for Digital Medicine, University Hospital Gießen-Marburg, Philipps University, Marburg, Germany, 8Université Milano Bicocca and Fondazione IRCSS S. Gerardo dei Tintori, Monza, Monza and Brianza, Italy, 9Univeristy of Bari "Aldo Moro", Italy, Bari, Bari, Italy, 10Department of Rheumatology, Military Hospital Mohammed V, Rabat, Morocco, 11Università Milano Bicocca, Milano, MILAN, Italy, 12University Hospital Fundacion Santa Fe de Bogota, Bogota, Colombia, 13Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Izmir Katip Celebi University. Arthritis Research Canada, Vancouver, British Columbia., Izmir, Turkey, 14Department of rehabilitation.Team METHODS, CRESS UMR 1153 – University of Paris Cité, Paris, France, 15Rheumatology Unit Department of Medicine and Therapeutics, Korle bu Teaching Hospital, University of Ghana Medical School, Accra, Ghana, 16Health Sciences Research Center (CReSS).Faculty of Medicine, International University of Rabat, Rabat, Morocco, 17Department of Physical Therapy, University of British Columbia, Vancouver, BC, Canada, 18Aga Khan University Medical College East Africa, Nairobi, Kenya, 19Department of Pediatrics, Division of Pediatric Rheumatology, University of Utah, Salt Lake City, UT, 20Department of Rheumatology, Saint-Joseph University and Hotel-Dieu de France, Beirut, Lebanon, 21Department of Biomedicine, Aarhus University & Rheumatology Sector, Medical Diagnostic Center, Silkeborg Regional Hospital, Silkeborg, Aarhus C, Denmark, 22Hospital Universitari de Bellvitge, Madrid, Spain

    Background/Purpose: Artificial intelligence (AI) is transforming rheumatology care, with innovative tools now empowering physicians and health professionals (HPRs). Our survey examines how adult and pediatric…
  • Abstract Number: 0138 • ACR Convergence 2025

    Evaluating Artificial Intelligence for Diagnosing Antiphospholipid Syndrome in Pulmonary Embolism Case Reports: A Prompt-Based Analysis

    Sami Rabah and Xiangyi Kang, Lincoln Medical Center, New York, NY

    Background/Purpose: Antiphospholipid syndrome (APS) is a complex autoimmune prothrombotic disorder that can present with venous or arterial thromboses, often masquerading as unprovoked pulmonary embolism (PE).…
  • Abstract Number: 0230 • ACR Convergence 2025

    An Epic journey – Therapeutic Drug Monitoring at an Academic Center

    Puja Khanna1 and Michael Rice2, 1Division of Rheumatology, University of Michigan, Ann Arbor, MI, 2Division of Gastroenterology, University of Michigan, Ann Arbor, MI

    Background/Purpose: Non-oncologic use of immunomodulatory agents is increasing. These drugs have a narrow, patient-specific therapeutic index, making therapeutic drug monitoring essential for safe prescribing. However,…
  • Abstract Number: 0235 • ACR Convergence 2025

    Mortality Trends due to Hypertension Related Deaths in Elderly Patients with Inflammatory Polyarthropathy: A CDC WONDER Analysis of 21 Years

    ZAUHA FAWAD MEMON1, Sibgha Fawad Memon2, Matia Fawad Memon2, REHAN ISHAQUE3, AHMAD SANAN4 and MUHAMMAD MUGHEES5, 1Peoples University of Medical and Health Sciences for Women, Tando Allahyar, Sindh, Pakistan, 2Peoples University of Medical and Health Sciences for Women, Tando Allahyar, Pakistan, 3LIAQUAT UNIVERSITY OF MEDICAL AND HEALTH SCIENCES, Jam Shoro, Sindh, Pakistan, 4KHYBER MEDICAL COLLEGE, Peshawer, Pakistan, 5Bahria University health Sciences, KARACHI, Pakistan

    Background/Purpose: Inflammatory polyarthropathy (IPA) is a group of chronic autoimmune disorders, common among older adults and contribute significantly to systemic inflammation and cardiovascular risk .…
  • Abstract Number: 0206 • ACR Convergence 2025

    Prospective Controlled Study of Humoral Response to Recombinant Zoster Vaccine in Cyclophosphamide-Treated Autoimmune Rheumatic Disease Patients: No Additional Impairment Compared to Other Immunosuppressive Therapies

    Nadia Emi Aikawa1, Julia Medeiros2, Sandra G Pasoto3, Ana C Medeiros-Ribeiro3, Luciana Parente Costa Seguro4, Ana Paula Luppino-Assad5, Emily Figueiredo Neves Yuki6, Lissiane Guedes7, Clovis Artur Silva8 and Eloisa Bonfa4, 1Rheumatology Division and Pediatric Rheumatology Unit, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, Sao Paulo, São Paulo, Brazil, 2Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, Sao Paulo, 3Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, Sao Paulo, Brazil, 4Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, São Paulo, Brazil, 5Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, SAO PAULO, Brazil, 6Faculdade de Medicina da USP, São Paulo, São Paulo, Brazil, 7Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, 8University of São Paulo, São Paulo, São Paulo, Brazil

    Background/Purpose: Recombinant zoster vaccine (RZV), represents a major advancement in the prevention of herpes zoster in autoimmune rheumatic diseases (ARD) patients. However, RVZ efficacy depends…
  • Abstract Number: 0114 • ACR Convergence 2025

    A rare variant in the Extl3 gene is associated with altered Wnt signaling pathway in a novel mouse model of axial spondyloarthritis

    Stéphane HILLIQUIN1, Karim IBRAHIM2, Olivier Fogel3, Marcio DO CRUZEIRO4, Patricia Albanese5, Xavier HOUARD6, Claire BARDET2 and Corinne MICELI-RICHARD7, 1Département de Rhumatologie, Hôpital Cochin, Assistance publique des Hôpitaux de Paris, Université Paris-Cité, Paris, France, PARIS, France, 2Université Paris Cité, Institut des maladies musculo-squelettiques, Laboratory Orofacial Pathologies, UMR-S 1333 Santé Orale and FHU-DDS-Net, Dental School, and Plateforme d’Imagerie du Vivant (PIV), Montrouge, France, Montrouge, France, 3AP-HP, Paris, France, 4Plateformes PDA et MouseT'IC, Institut Cochin, Université Paris Cité, Paris, France, Paris, France, 5Laboratoire Gly-CREET, Université Paris-Est Créteil Val de Marne (UPEC) Faculté des sciences et technologies, Créteil, France, 6Centre de Recherche Saint-Antoine, UMR_S938 INSERM /Sorbonne Université, Paris, France, PARIS, France, 7Rheumatology Department, Hôpital Cochin, APHP, PARIS, France

    Background/Purpose: The ossification processes observed in ankylosing spondylitis (AS) remain incompletely understood. Substantial evidence from both human and animal studies implicates the Wnt signaling pathway…
  • Abstract Number: 0180 • ACR Convergence 2025

    Digital Transformation in IMID Care: Results from the Implementation of IMIDOC

    JOSE INIESTA-CHAMORRO1, Marta Novella-Navarro2, Diego Benavent3, HELENA BORREL-PAÑOS4, Xabier Michelena Vegas5, Javier Bachiller6, Verónica García García7, ESTHER ESPARTAL4, LETICIA LOJO-OLIVEIRA8, Enrique Calvo-Aranda9, José Rodríguez gago10, Gema Bonilla11, Irene Monjo Henry2, Victoria Navarro-Compan12, Jaime Arroyo10, Eugenio de Miguel2, Mariana Díaz-Almirón13, cARMEN ALEGRE10, ENRIQUE J GÓMEZ14 and Chamaida Plasencia-Rodríguez2, 11Biomedical Engineering and Telemedicine Centre, ETSIT, Center for Biomedical Technology, Universidad Politéctica de Madrid, TELEMEDICINE, MADRID, 2Hospital Universitario La Paz, Madrid, Spain, 3Hospital Universitari de Bellvitge, Madrid, Spain, 44HOSPITAL UNIVERSITARIO VALL D´HEBRON, RHEUMATOLOGY, BARCELONA, Spain,, BARCELONA, 5Hospital Universitari Vall Hebron, Barcelona, Spain, 6Hospital Ramon y Cajal, Madrid, Madrid, Spain, 7Ramón y Cajal University Hospital, MADRID, Spain, 8Hospital Universitario Infanta Leonor, Madrid, Spain, 9Department of Rheumatology, Hospital Universitario Infanta Leonor / Universidad Complutense de Madrid, Madrid, Spain, madrid, 10Hospital Universitario La Paz, MADRID, 11Hospital Universitario La Paz, Rheumatology, Madrid, Madrid, Spain, 12Department of Rheumatology, La Paz University Hospital, IdiPaz, Madrid, Spain, 13LIMA, Advanced Medical Informatics Lab, La Paz Research Institute, IdiPAZ, Madrid, Spain, 141Biomedical Engineering and Telemedicine Centre, ETSIT, Center for Biomedical Technology, Universidad Politéctica de Madrid, TELEMEDICINE, MADRID, Spain,, MADRID

    Background/Purpose: Rheumatoid arthritis (RA) and spondyloarthritis (SpA) are immune-mediated inflammatory diseases (IMIDs) characterized by joint and spinal inflammation, leading to functional impairment. Their management requires…
  • Abstract Number: 0013 • ACR Convergence 2025

    Discovery and Characterization of SIM0710, a Novel B and T Lymphocyte Attenuator (BTLA) Agonistic Antibody for Autoimmune/Inflammatory Diseases

    Xiaofeng Zhao1, Xiaoqing Liu1, Yuxi Yan2, Tiezheng Liu3, Yong Fu3, Yulan Hu2, Kangmin Zhou2, Minyun Zhou4, Yingying Hu2 and Shunwei Zhu2, 1State Key Laboratory of Neurology and oncolog Drug Development, Simcere Pharmaceutical Group, Nanjing, China (People's Republic), 2State Key Laboratory of Neurology and Oncology Drug Development, Simcere Pharmaceutical Group, Shanghai, China (People's Republic), 3State Key Laboratory of Neurology and Oncology Drug Development, Simcere Pharmaceutical Group, Nanjing, China (People's Republic), 4State Key Laboratory of Neurology and Oncology Drug Development, Simcere Pharmaceutical group, Nanjing

    Background/Purpose: B and T lymphocyte attenuator (BTLA) is an immune checkpoint molecule that contributes to the regulation of T cell, B cell and dendritic cell…
  • Abstract Number: 0192 • ACR Convergence 2025

    Digital Empowerment on Hold: Adoption Gaps in Prescribable Digital Health Applications – A National Cross-Sectional Study from Germany

    Phillip Kremer1, Daniel Fink2, Harriet Morf3, Hannah Labinsky4, Karolina Gente5, Peer Aries6, Martin Krusche1, Sebastian Kuhn7, Axel Hueber8 and Johannes Knitza9, 1Division of Rheumatology and Systemic Inflammatory Diseases, III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, 2Rheumazentrum Mittelhessen, Bad Endbach, Germany, 3Department of Medicine 3 - Rheumatology & Immunology, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg and Uniklinikum Erlangen, Erlangen, Germany, 4University Hospital of Wuerzburg, Würzburg, Germany, 5Department of Internal Medicine V - Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Baden-Wurttemberg, Germany, 6Department of Rheumatology, Immunologikum, Hamburg, Germany, 7Institute for Digital Medicine, University Hospital of Giessen and Marburg, Philipps University Marburg, Marburg, Germany, 8Klinikum Nuernberg, Nuernberg, Germany, 9Institute for Digital Medicine, University Hospital Gießen-Marburg, Philipps University, Marburg, Germany

    Background/Purpose: Rheumatic and musculoskeletal diseases (RMDs) are chronic conditions that require complex, multidisciplinary care. Since 2020, digital health applications (DiGAs) have been available for prescription…
  • Abstract Number: 0225 • ACR Convergence 2025

    Positive anxiety, depression and/or fibromyalgia screening on validated MDHAQ indices is seen in 30-50% of routine care patients with all rheumatic diagnoses

    Juan Schmukler1, Tengfei Li2 and Theodore Pincus1, 1Rush University Medical Center, Chicago, IL, 2Rush, chicago, IL

    Background/Purpose: Comorbid anxiety (ANX), depression (DEP), and fibromyalgia(FM) are reported as more common in patients with rheumatoid arthritis (RA) and other rheumatic diagnoses than in…
  • Abstract Number: 0136 • ACR Convergence 2025

    Beyond Thrombosis: Histological Spectrum, Predictors and Outcomes of Renal Involvement in Primary Antiphospholipid Syndrome: A Single-Centre Cohort Study

    RITESH KUMAR MISHRA1, SUBIN PHILIP2, RIZWANA NAUSHAD2, AISHWARYA GOPAL3, Chengappa Kavadichanda2, CHRISTINA MARIASELVAM2, RAJESH N G2, Molly mary Thabah3 and VIR SINGH NEGI2, 1JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH, Bhubaneswar, India, 2JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH, PUDUCHERRY, Puducherry, India, 3JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH, PUDUCHERRY, India

    Background/Purpose: Renal involvement in primary APS is underrecognized and histologically diverse, encompassing both vascular and glomerular pathology. We aimed to describe the histopathology, outcomes of…
  • Abstract Number: 0215 • ACR Convergence 2025

    Impact of Global Review on Comorbidity Management in Inflammatory Arthritis Patients

    Alexandra Kobza1, Camille Bourgeois2, Olivier Fogel3, Maxime Dougados4 and Anna Molto5, 1University of Calgary, North Vancouver, BC, Canada, 2Hospital general universitario Gregorio Marañon, Madrid, Madrid, Spain, 3AP-HP, Paris, France, 4Department of Medicine, Hopital Cochin, Universite de Paris, Paris, France, 5Assistance Publique Hôpitauxde Paris, Paris, France

    Background/Purpose: Patients with inflammatory arthritis (IA), including rheumatoid arthritis (RA) and spondyloarthritis (SpA), face elevated risk for comorbidities that complicate disease management. Although rheumatology societies…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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