Abstracts Archive - Page 514 of 2425 - ACR Meeting Abstracts

Abstract Number: PP21 • ACR Convergence 2022
What Lies Beneath: Making Rheumatoid Arthritis Visible for the Seronegative Patient Through Blood Work
Shilpa Venkatachalam, Global Healthy Living Foundation, New York, NY
Background/Purpose: When I first received my Rheumatoid Arthritis (RA) diagnosis 5 years ago, I experienced a combination of relief and disbelief. Relief because now all…
Abstract Number: PP15 • ACR Convergence 2022
Coordination of Care by a Healthcare Team for Unexpected and Unusual Side Effects Occurring During a Global Pandemic
Laura Genoves, Arthritis Foundation, Bainbridge Island, WA
Background/Purpose: I am a patient who lives with moderate to severe RA. My quality of life is dependent on medications such as a biologic, DMARDs…
Abstract Number: 2260 • ACR Convergence 2022
Transcutaneous Vagal Nerve Stimulation Improves Destabilized Medial Meniscus-Induced Osteoarthritis Pain Associated with Significant Serum Biomarker Changes
Shivmurat Yadav¹, Monika Niewiadomska¹, Lynsie Morris², Taylor Conner², Jessica Lumry², Sanique South³, Emmaline Prinz², Matlock Jeffries², Timothy Griffin², Stavros Stavrakis¹ and Mary Beth Humphrey¹, ¹University of Oklahoma Health Sciences Center, Oklahoma City, OK, ²Oklahoma Medical Research Foundation, Oklahoma CIty, OK, ³Oklahoma Medical Research Foundation, Okahoma City, OK
Background/Purpose: Osteoarthritis (OA) is the most common form of arthritis, affecting over 32.5 million US adults and characterized by pain, stiffness, swelling and functional disability.…
Abstract Number: PP06 • ACR Convergence 2022
Search for a New Rheumatologist; What Happened When My Trusted Rheumatologist Retired
Lawrence Phillips, Noblesville, IN
Background/Purpose: I was diagnosed with rheumatoid arthritis (RA) in 1999. In 2015 and 2019, two surgeons independently diagnosed me with ankylosing spondylitis (AS) following two…
Abstract Number: PP19 • ACR Convergence 2022
Living with Rheumatoid Arthritis in a Rural Farming Community: How I Found a Rheumatologist and Got Targeted Treatment
Vanessa Kerr, Mexico, MO
Background/Purpose: I'm Vanessa and I've been married to James, a farmer, for 27 years. We have 5 children and when my fourth was born, I…
Abstract Number: 2273 • ACR Convergence 2022
Waning Vaccine Response After Primary Vaccine Series: Results from the Covid19 Vaccine Response in Rheumatology Patients (COVER) Study
Amy Mudano¹, Gary Cutter², Ted Mikuls³, Geoffrey Thiele⁴, Mark Law⁴, Bart Hamilton⁴, Michael Zikry⁵, Kelly Y. Chun⁶, Monique Bastidas⁷, Michael George⁸, Lisa Williams⁹, Kevin Winthrop¹⁰, Mark Busch¹¹, Stanley Cohen¹², Roman Czubatyj¹³, Rajesh Kataria¹⁴, Reshma Khan¹⁵, Soha Mousa¹⁶, Jose Pando¹⁷, Elizabeth Perkins¹⁸, Shanmugapriya Reddy¹⁹, Delfin Santos²⁰, Joy Schechtman²¹, Frank Scott²², Sucharitha Shanmugam²³, Atul Singhal²⁴, John Tesser²⁵, John Tower²⁶, Swamy Venuturupalli²⁷, Sean Joseph Wollaston²⁸, Conrad Ziembinski²⁹ and Jeffrey Curtis³⁰, ¹Illumination Health, Hoover, AL, ²University of Alabama at Birmingham, Birmingham, AL, ³Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, ⁴University of Nebraska Medical Center, Omaha, NE, ⁵LabCorp, Burlington, NC, ⁶Labcorp, Calabasas, CA, ⁷LabCorp, Northridge, CA, ⁸University of Pennsylvania, Philadelphia, PA, ⁹Illumination Heath, Hoover, AL, ¹⁰Oregon Health & Science University, Portland, OR, ¹¹Family Arthritis Center-Jupiter, Jupiter, FL, ¹²Metroplex Clinical Research Center, Pittsburgh, PA, ¹³Arthritis Physicians LLC, Rochester Hills, MI, ¹⁴Southern Ohio, Wheelersburg, OH, ¹⁵Palm Beach Rheumatology and Wellness, Jupiter, FL, ¹⁶Arthritis and Rheumatology of Southwest Ohio, Liberty Township, OH, ¹⁷Rheumatology Consultants of DE, Lewes, DE, ¹⁸Rheumatology Care Center, Hoover, AL, ¹⁹Southwest Florida Rheumatology, Riverview, FL, ²⁰Rochester Rheumatology, Rochester Hills, MI, ²¹SunValley Arthritis Center, Peoria, AZ, ²²Arthritis Medical Center, Arroyo Grande, CA, ²³Rheumatology and Arthritis Care Center, Exton, PA, ²⁴Southwest Rheumatology Research, Mesquite, TX, ²⁵Arizona Arthritis & Rheumatology Associates, Phoenix, AZ, ²⁶Arthritis Physicians LLC, Rochester, MI, ²⁷Cedars-Sinai Medical Center, Los Angeles, CA, ²⁸Rheumatology Associates, North Hollywood, CA, ²⁹CZ Rheumatology, Coral Springs, FL, ³⁰Division of Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Given possible increased risk of COVID-19 in patients with autoimmune conditions, there is a need to better understand the immunogenicity and safety of SARS-CoV-2…
Abstract Number: 2258 • ACR Convergence 2022
Relative Frequencies of the Spectrum of MRI Lesions in the Sacroiliac Joints of Healthy Individuals and Patients with Non-Specific Back Pain: What Is the Impact of Increasing Age?
Ulrich Weber¹, Susanne Pedersen², Mikkel Østergaard³, Pedro Machado⁴, Xenofon Baraliakos⁵, Robert G Lambert⁶ and Walter P Maksymowych⁷, ¹Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, ²Rigshospitalet, København, Denmark, ³Rigshospitalet, University of Copenhagen, Glostrup, Denmark, ⁴University College London, London, United Kingdom, ⁵Rheumazentrum Ruhrgebiet Herne, Herne, Germany, ⁶University of Alberta, Edmonton, AB, Canada, ⁷Department of Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Previous studies of patients with axial spondyloarthritis (axSpA) have demonstrated that certain MRI structural lesions in the sacroiliac joints (SIJ), notably erosions, has high…
Abstract Number: 2266 • ACR Convergence 2022
Platelet-selectin Prime Lupus Neutrophils to Produce Mitochondrial ROS and Participate in SLE Pathogenesis
Marc Scherlinger¹, Pierre Vacher², Vivien Guillotin³, Isabelle Douchet⁴, Christophe Richez⁵ and Patrick Blanco⁴, ¹BIDMC Harvard University, Boston, MA, ²INSERM U1218, Bordeaux, France, ³CHU de Bordeaux, Bordeaux, France, ⁴UMR-CNRS 5164 Immunoconcept, Bordeaux, France, ⁵CHRU Bordeaux, Bordeaux, France
Background/Purpose: In patients with active systemic lupus erythematosus (SLE), circulating platelets have an activated phenotype characterized by the expression of P-selectin (CD62P). We have shown…
Abstract Number: 2263 • ACR Convergence 2022
Nanotherapeutic Approaches for the Treatment of Post-traumatic Osteoarthritis
Luke Springer¹, Kelsey Collins², Huimin Yan², Ying Hu³, Farshid Guilak², Samuel Wickline⁴, Hua Pan² and Christine Pham², ¹Washington University School of Medicine, St. Louis, MO, ²Washington University School of Medicine, Saint Louis, MO, ³Washington University, Saint Louis, MO, ⁴University of South Florida, Tampa, FL
Background/Purpose: Osteoarthritis (OA) represents the most common form of arthritis and is a major cause of morbidity in the aging population. Post-traumatic OA (PTOA) is…
Abstract Number: 2262 • ACR Convergence 2022
Albumin-hitchhiking MMP13 siRNA Conjugate (siMMP13< (EG18L)2) for the Treatment of Rheumatic Disease
Juan Colazo¹, Ella Hoogenboezem¹, Fang Yu¹, Veeraj Shah¹, Justin Lo¹, Hongsik Cho², Karen Hasty², Leslie Crofford³ and Craig Duvall¹, ¹Department of Biomedical Engineering, Vanderbilt University, Nashville, Nashville, TN, ²Department of Orthopaedic Surgery and Biomedical Engineering, Memphis VA Medical Center, Memphis, TN, ³Vanderbilt University Medical Center, Nashville, TN
Background/Purpose: Osteoarthritis (OA) and rheumatoid arthritis (RA) decrease quality of life due to joint destruction, pain, and decreased function. Multiple joint osteoarthritis (MJOA) can occur…
Abstract Number: 2261 • ACR Convergence 2022
Pain in Osteoarthritis – Identification of GPR34 and GPR150 as Novel Targets in the Dorsal Root Ganglia
Matthew Wood¹, Terese Geraghty², David Thomas³, Alia Obeidat¹, Jun Li², Richard Miller⁴, Rachel Miller¹ and Anne-Marie Malfait⁵, ¹Rush University Medical Center, Chicago, IL, ²Rush University, Chicago, IL, ³University of Minnesota Internal Medicine Residency, St. Paul, MN, ⁴Northwestern University, Evaston, IL, ⁵Rush University, Oak Park, IL
Background/Purpose: Osteoarthritis (OA) is a leading cause of chronic pain worldwide. Currently available pain-alleviating therapies are often inadequate and associated with serious adverse effects, resulting…
Abstract Number: 1880 • ACR Convergence 2022
Vaccine Hesitancy Among Patients with Idiopathic Inflammatory Myopathies and Rheumatic Diseases in 2021-2022: A Comparative Analysis of COVID-19 Vaccination in Autoimmune Diseases Surveys
Naveen R¹, Mrudula Joshi², Parikshit Sen³, Vishwesh Agarwal⁴, Samuel Shinjo⁵, Sinan Kardes⁶, James B. Lilleker⁷, Hector Chinoy⁸, Ashima Makol⁹, Oliver Distler¹⁰, Minchul Kim¹¹, Elena Nikiphorou¹², Ai Lyn Tan¹³, Babur Salim¹⁴, Tamer A Gheita¹⁵, Nelly Ziade¹⁶, Tsvetelina Velikova¹⁷, Tulika Chatterjee¹¹, Arvind Nune¹⁸, Marcin Milchert¹⁹, Ioannis Parodis²⁰, Abraham Edgar Gracia-Ramos²¹, Albert Selva O’Callaghan²², Miguel Angel Saavedra Salinas²³, Lorenzo Cavagna²⁴, Masataka Kuwana²⁵, Johannes Knitza²⁶, Jessica Day²⁷, Carlos Enrique Toro Gutiérrez²⁸, Carlo Caballero²⁹, Dzifa Dey³⁰, Erick Zamora Tehozol³¹, Jorge Rojas Serrano³², Ignacio Garcia-De La Torre³³, Iris Colunga³⁴, Javier Merayo-Chalico³⁵, John Pauling³⁶, Chris Wincup³⁷, Armen Yuri Gasparyan³⁸, Vikas Agarwal¹, Rohit Aggarwal³⁹ and Latika Gupta⁴⁰, ¹Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, ²Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, India, ³Maulana Azad Medical College, New Delhi, India, ⁴Mahatma Gandhi Missions Medical College, Lucknow, India, ⁵Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, Brazil, ⁶Istanbul University, Istanbul, Turkey, ⁷The University of Manchester, Manchester, United Kingdom, ⁸The University of Manchester, Sale, United Kingdom, ⁹Mayo Clinic, Rochester, MN, Rochester, MN, ¹⁰Department of Rheumatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland, ¹¹University of Illinois College of Medicine Peoria, Peoria, IL, ¹²Leiden University Medical Center & King's College London, London, United Kingdom, ¹³University of Leeds, Leeds, United Kingdom, ¹⁴Fauji foundation hospital Rawalpindi, Rawalpindi, Pakistan, ¹⁵Rheumatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt, ¹⁶Saint-Joseph University, Beirut, Lebanon, ¹⁷Sofia University St. Kliment Ohridski, Sofia, Bulgaria, ¹⁸Southport and Ormskirk Hospital NHS Trust, Southport, United Kingdom, ¹⁹Pomeranian Medical University in Szczecin, Szczecin, Poland, ²⁰Karolinska Institutet, Stockholm, Sweden, ²¹Instituto Mexicano del Seguro Social, Ciudad de México, Mexico, ²²Hospital Universitari Vall d'Hebron, Barcelona, Spain, ²³IMSS, Ciudad de México, Mexico, ²⁴Università di Pavia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, Pavia, Italy, ²⁵Nippon Medical School Graduate School of Medicine, Tokyo, Japan, ²⁶Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany; Deutsches Zentrum Immuntherapie, Friedrich-Alexander-UniversityErlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, ²⁷Walter and Eliza Hall Institute, Melbourne, Australia, ²⁸Internal Medicine and Rheumatology, Reference Center for Osteoporosis, Rheumatology & Dermatology. Pontificia Javeriana University, Calí, Colombia, ²⁹Universidad del Norte, Barranquilla, Colombia, ³⁰University of Ghana School of Medicine and Dentistry, Accra, Ghana, ³¹Centro Medico Pensiones, Merida, Mexico, ³²Hospital Angeles Villahermosa, Ciudad de México, Mexico, ³³Centro de Est. de Inv. Bas. y Clinica, S.C., Guadalajara, Mexico, ³⁴Hospital Universitario UANL, Monterrey, Mexico, ³⁵Instituto Nacional de Ciencias Medicas y Nutricion "Salvador Zubiran", Ciudad de México, Mexico, ³⁶North Bristol NHS Trust, Bristol, United Kingdom, ³⁷Rayne Institute, University College London, London, United Kingdom, ³⁸Dudley Group NHS Foundation Trust, Dudley, United Kingdom, ³⁹Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, ⁴⁰Royal Wolverhampton Trust, Wolverhampton/University of Manchester, United Kingdom
Background/Purpose: Patients with comorbidities and active rheumatic disease have increased morbidity and hospitalization following SARS-CoV-2 infection. While vaccination has decreased this, many unknown factors still…
Abstract Number: 2257 • ACR Convergence 2022
MRI Spinal Lesions in Patients Without MRI or Radiographic Lesions in the Sacroiliac Joints Typical of Axial Spondyloarthritis
Walter P Maksymowych¹, Mikkel Østergaard², Xenofon Baraliakos³, Pedro Machado⁴, Susanne J. Pedersen⁵, Ulrich Weber⁶, Iris Eshed⁷, Manouk de Hooge⁸, Joachim Sieper⁹, Denis Poddubnyy¹⁰, Martin Rudwaleit¹¹, Désirée van der Heijde¹², Robert Landewé¹³ and Robert G Lambert¹⁴, ¹Department of Medicine, University of Alberta, Edmonton, AB, Canada, ²Rigshospitalet, University of Copenhagen, Glostrup, Denmark, ³Rheumazentrum Ruhrgebiet Herne, Herne, Germany, ⁴University College London, London, United Kingdom, ⁵Rigshospitalet, University of Copenhagen, Copenhagen, Denmark, ⁶Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, ⁷Sheba Medical Center, Tel Aviv, Israel, ⁸Ghent University Hospital, Luxembourg, Luxembourg, ⁹Charité - Universitätsmedizin, Berlin, Berlin, Germany, ¹⁰Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité – Universitätsmedizin Berlin, Berlin, Germany, ¹¹University of Bielefeld, Klinikum Bielefeld, Bielefeld; Germany Klinikum Bielefeld and Charité Berlin, Germany, and Gent University, Gent, Belgium, ¹²Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands, Leiden, Netherlands, ¹³Amsterdam University Medical Center, Meerssen, Netherlands, ¹⁴University of Alberta, Edmonton, AB, Canada
Background/Purpose: There is limited data as to the frequency of spinal lesions on MRI in patients without MRI or radiographic features typical of sacroiliac joint…
Abstract Number: 1878 • ACR Convergence 2022
Identification of Serum Biomarkers Associated with Muscle Inflammation Detected on MRI in Polymyositis/dermatomyositis
Haruna Matsuo¹, Toshimasa Shimizu¹, Tomohiro Koga¹, Nozomi Oki², Masataka Uetani² and Atsushi Kawakami³, ¹Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ²Department of Radiological Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ³Department of Immunology and Rheumatology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan
Background/Purpose: Muscle inflammation is a major clinical manifestation in patients with polymyositis/dermatomyositis (PM/DM). Phenotypes of PM/DM patients, especially those with interstitial lung diseases, are known…
Abstract Number: 1881 • ACR Convergence 2022
Association Study Between anti-TIF1γ Antibody and Development of Neoplasia in Three Tertiary Hospitals
Marina Pavía Pascual¹, Isidro Jarque Canalias¹, Jose Luis Morell², Jesús Loarce Martos³, Lorena Montaño Tapia⁴, Olga Rusinovich¹, Natalia de la Torre-Rubio¹, Maria Machattou¹, Pablo Navarro Palomo¹, Maria Carmen Barbadillo Mateos¹, Monica Fernandez Castro⁵, Blanca Garcia-Magallon¹, Maria Hildegarda Godoy Tundidor¹, Carolina Merino¹, JESUS SANZ SANZ¹, Jose Luis Andreu¹ and Jose Campos¹, ¹Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain, ²Hospital Universitario Ramon y Cajal, Madrid, Spain, ³Hospital Universitario Ramón y Cajal, Madrid, Spain, ⁴Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, Spain, ⁵Puerta de Hierro Hospital, Madrid, Spain
Background/Purpose: Anti-transcriptional intermediary factor 1γ (anti-TIF 1γ) antibody is robustly linked with malignancy-associated dermatomyositis (DM) in adults, but its specificity varies widely between series. TIF…

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