ACR Meeting Abstracts

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  • Abstract Number: PP14 • ACR Convergence 2022

    The Use of Social Support as Treatment

    Aleta McLean, Open Hand Atlanta, Atlanta, GA

    Background/Purpose: The months leading up to my diagnosis were frustrating. Initially my hair started falling out. I was told it was stress related. I was…
  • Abstract Number: 2174 • ACR Convergence 2022

    Influence of Immunosuppressive Therapy on Gastrointestinal Symptoms in Patients with Systemic Sclerosis

    Lea Stamm1, Alexandru Garaiman1, Norina Zampatti1, Mike Becker1, Cosimo Bruni1, Rucsandra Dobrota1, Muriel Elhai1, Sherif Ismail2, Suzana Jordan1, Aurora Tatu3, Oliver Distler1 and Carina Mihai1, 1Department of Rheumatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland, 2Department of Internal Medicine, National Research Center, Cairo, Egypt, 3Department of Gastroenterology, University Hospital Zurich, University of Zurich, Zürich, Switzerland

    Background/Purpose: The gastrointestinal (GI) tract is frequently affected in systemic sclerosis (SSc), leading to considerable morbidity and even mortality. While important progress has been made…
  • Abstract Number: 2236 • ACR Convergence 2022

    Association of microRNA-30b Plasma Expression with Fibromyalgia Clinical Features and with Corneal Small Nerve Fiber Pathology

    Laura Aline Martínez Martínez1, Fausto Sánchez Muñoz1, Manuel Ramírez Fernández2, Yaneli Juárez Vicuña1, Mario Peña-Peña1, Carlos Alfonso Guzman Martin1, Itzel Palafox Sosa1 and Manuel Martínez-Lavín1, 1Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de México, Mexico, 2APEC Hospital de la ceguera, Ciudad de México, Mexico

    Background/Purpose: There is a clear association between fibromyalgia and small fiber neuropathy. Dorsal root ganglia contain the small nerve fiber nuclei. Severe fibromyalgia is associated…
  • Abstract Number: PP06 • ACR Convergence 2022

    Search for a New Rheumatologist; What Happened When My Trusted Rheumatologist Retired

    Lawrence Phillips, Noblesville, IN

    Background/Purpose: I was diagnosed with rheumatoid arthritis (RA) in 1999. In 2015 and 2019, two surgeons independently diagnosed me with ankylosing spondylitis (AS) following two…
  • Abstract Number: 2041 • ACR Convergence 2022

    Single Cell Atlas of Minor Salivary Glands Reveals Key Differential Cellular and Functional Players in Sjögren’s and Sicca Syndrome

    SABA NAYAR1, Jason D. turner1, Saba Asam1, Charlotte G. Smith1, Serena Colfrancesco2, Ana Teodósio1, Joe Flint1, David H Gardner1, Professor Simon Bowman3, Adam Croft1, Andrew Filer1, Benjamin A. Fisher1, Christopher Buckley4 and Francesca Barone5, 1University of Birmingham, Birmingham, United Kingdom, 2University of Rome, Rome, Italy, 3University Hospitals Birmingham, Birmingham, United Kingdom, 4University of Oxford, Oxford, United Kingdom, 5University of Birmingham, Needham, MA

    Background/Purpose: Sjögren's syndrome (SjS) shares a series of symptoms with non-SjS Sicca syndrome, a salivary gland disease characterised by glandular dysfunction and dryness. However, unlike…
  • Abstract Number: 1639 • ACR Convergence 2022

    A Phase 3, 56-Week, Multicenter, Randomized, Double-Blind, Placebo Controlled Trial (OA-11) to Evaluate the Efficacy and Safety of a Single Injection of Lorecivivint Injected in the Target Knee Joint of Moderate to Severe Osteoarthritis Participants

    Yusuf Yazici1, Christopher Swearingen2, Heli Ghandehari3, Jon Britt4, ismail simsek5, Mark Fineman6, Sarah Kennedy2, Jeyanesh Tambiah7 and Timothy McAlindon8, 1New York University School of Medicine, La Jolla, CA, 2Biosplice Therapeutics, Inc, San Diego, CA, 3Biosplice Therapeutics, Inc., San Diego, CA, 4Biosplice Therapeutics, Inc., Los Angeles, CA, 5Alpine Immunesciences, San Diego, CA, 6Biosplice Therapeutics, San Diego, CA, 7Biosplice Ther Inc., San Diego, CA, 8Tufts Medical Center, Arlington, MA

    Background/Purpose: Knee osteoarthritis (OA) is a common joint disorder associated with pain, disability, and joint damage. There remains a large unmet need for treatments that…
  • Abstract Number: 1627 • ACR Convergence 2022

    BAFF-var Is a New Predisposing Factor for Primary Sjögren’s Syndrome (pSS) and Impacts Disease Activity

    Marie Dulin1, Maxime Beydon2, Bineta Ly3, Veronique Le Guern4, Raphaèle Seror5, Xavier Mariette6 and Gaetane Nocturne7, 1Kremlin Bicêtre Hospital - APHP, Paris, France, 2Université Paris Cité, Paris, France, 3INSERM UMR1184, Le Kremlin Bicêtre, France, 4Hôpital Cochin, Paris, France, 5University Hospital Paris-Saclay, Le Kremlin Bicêtre, France, 6Paris-Saclay University, Rueil Malmaison, Ile-de-France, France, 7APHP, Le Kremlin Bicêtre, France

    Background/Purpose: Chronic B cell activation plays a key role in pSS pathogeny. BAFF (B-cell activating factor) is largely involved in this process and positive results…
  • Abstract Number: 1975 • ACR Convergence 2022

    Identifying MicroRNAs Associated with Neuropathic Pain in Patients with Rheumatoid Arthritis (RA)

    Lissette Delgado-Cruzata1, Milena Rodriguez Alvarez2, Veronika Zenkeviciute3, Nickolas Almodovar3 and Toni-Ann Bravo3, 1City University of New York, New York, NY, 2SUNY Downstate Medical Center, New York, NY, 3John Jay College, CUNY, New York, NY

    Background/Purpose: Neuropathic pain is one of the most common clinical characteristics of rheumatoid arthritis (RA). It often does not subside with the use of DMARD,…
  • Abstract Number: 2268 • ACR Convergence 2022

    Recurrent Thrombosis Risk in Non-anticoagulated Antiphospholipid Syndrome Patients: A Prospective Case-Control Study from AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION) Clinical Database and Repository (“Registry”)

    Cecile Yelnik1, Zeynep Belce Erton2, Elodie Drumez3, Dachi Cheildze2, Danieli Castro Oliveira de Andrade4, Ann E Clarke5, Maria G. Tektonidou6, Vittorio Pengo7, Savino Sciascia8, Amaia Ugarte9, H Michael Belmont10, Mª Angeles Aguirre11, Paul fortin12, maria gerosa13, Flavio Victor Signorelli14, Tatsuya Atsumi15, Zhouli Zhang16, Hannah Cohen17, D. Ware Branch18, Denis Wahl19, Laura Andreoli20, Esther Rodriguez Almaraz21, Michelle Petri22, Ricard Cervera23, Yu Zuo24, Bahar Artim-Esen25, Guillermo Pons-Estel26, Rohan Willis27, Maria Laura Bertolaccini28, Robert Roubey29, Doruk Erkan2 and on behalf of APS ACTION On Behalf Of APS ACTION2, 1Lille University, Lille, France, 2Hospital for Special Surgery, New York, NY, 3Université de Lille, Lille, France, 4Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, 5University of Calgary, Division of Rheumatology, Cumming School of Medicine, Calgary, AB, Canada, 6National and Kapodistrian University of Athens, Athens, Greece, 7Padova University Hospital, Padova, Italy, 8University of Turin, Torino, Italy, 9BioCruces Bizkaia Health Research Institute, Barakaldo, Spain, 10NYU School of Medicine, New York, NY, 11Maimonides Institute for Biomedical Research of Córdoba, Cordoba, Spain, 12CHU de Québec, Pavillon CHUL, Québec, Canada, 13University of Milan, Milano, Italy, 14Universidade do Estado do Rio de Janeiro, Rio De Janeiro, Brazil, 15Hokkaido University, Sapporo, Japan, 16Peking University First Hospital, Beijing, China, 17University College London, London, United Kingdom, 18University of Utah, Salt Lake City, UT, 19Université de Nancy, Nancy, France, 20Rheumatology and Clinical Immunology Unit, ASST Spedali Civili and University of Brescia, Brescia, Italy, 21Hospital Universitario 12 de Octubre, Madrid, Spain, 22Johns Hopkins University School of Medicine, Division of Rheumatology, Baltimore, MD, 23Hospital Clínic de Barcelona, Barcelona, Spain, 24University of Michigan, Ann Arbor, MI, 25Istanbul University, Istanbul, Turkey, 26CREAR, Rosario, Argentina, 27University of Texas Medical Branch, Galveston, TX, 28King's College London, London, United Kingdom, 29University of North Carolina, Chapel Hill, NC

    Background/Purpose: Long-term anticoagulation is the standard of care for antiphospholipid syndrome (APS) patients with macrovascular thrombosis. However, in daily practice, long-term anticoagulation may not be…
  • Abstract Number: PP17 • ACR Convergence 2022

    Engaging with the Spoon Theory: How I Make Decisions Using a Cost-Benefit Analysis That Works to Improve My Mental Health While Living with RA

    Stephanie Aleite, AiArthritis, St. Louis, MO

    Background/Purpose: Patients living with rheumatoid arthritis (RA) often also live with comorbid mental health conditions. Regardless of diagnosed mental health condition, living with a chronic…
  • Abstract Number: PP02 • ACR Convergence 2022

    Patient Mobilization for Vaccine Access and Improved Care During the COVID Pandemic

    Marie-Claude Beaulieu1, Ines Colmegna2, Nathalie Amiable3, Jean Légaré4 and Paul Fortin5, 1Universite de Sherbrooke, Sherbrooke, QC, Canada, 2The Research Institute of the McGill University Health Centre, Montreal, QC, Canada, 3CHU de Québec, Quebec, QC, Canada, 4QC, Canada, 5CHU de Quebec - Universite Laval, Quebec, QC, Canada

    Background/Purpose: The COVID pandemic was particularly difficult for persons like me living with rheumatoid arthritis and immunosuppressed. I had to impose myself months of isolation…
  • Abstract Number: 2245 • ACR Convergence 2022

    Feasibility and Efficacy of a Peer Education Program to Improve Patient Engagement in Lupus Clinical Trials

    Saira Sheikh1, Caroline Donovan2, Carla Menezes2, Albert T. Roy2, Andrew Simkus3, Diane Gross4, Anca Askanase5, Rosalind Ramsey-Goldman6, Vikas Majithia7, Nicole Wanty3, Annie McNeill3, Kristen Holtz3 and S. Sam Lim8, 1University of North Carolina at Chapel Hill, Chapel Hill, NC, 2Lupus Therapeutics, LLC, New York, NY, 3KDH Research & Communication, Atlanta, GA, 4Lupus Research Alliance, New York, NY, 5Columbia University Medical Center, New York, NY, 6Northwestern University Feinberg School of Medicine, Chicago, USA, Chicago, IL, 7University of Mississippi Medical Center, Ridgeland, MS, 8Emory University, Atlanta, GA

    Background/Purpose: To assess outcomes related to Lupus Therapeutics' Patient Advocates for Lupus Studies (LT-PALS) a peer-to-peer clinical trial (CT) education program designed to improve CT…
  • Abstract Number: 2184 • ACR Convergence 2022

    CaMK4 Controls the Humoral Response via the T Follicular Helper Compartment and Regulates Autoimmunity

    Marc Scherlinger1, Hao Li2, Wenliang Pan2, Maria Tsokos1 and George Tsokos2, 1BIDMC Harvard University, Boston, MA, 2Division of Rheumatology and Clinical Immunology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA

    Background/Purpose: Systemic lupus erythematosus (SLE) is characterized by a dysregulated T cell compartment and production of autoantibodies leading to organ damage. We previously identified that…
  • Abstract Number: 2053 • ACR Convergence 2022

    Current State and Completeness of Reporting Clinical Prediction Models Using Machine Learning in Systemic Lupus Erythematosus: A Systematic Review

    Claudia Mendoza-Pinto1, Ivet Etchegaray-Morales2, Pamela Munguía-Realpozo2, David Angel Osorio-Peña2, Socorro Méndez-Martínez1 and Mario Garcia-Carrasco2, 1Instituto Mexicano del Seguro Social, Puebla, Mexico, 2Benemérita Universidad Autónoma de Puebla, Puebla, Mexico

    Background/Purpose: There is increased interest in machine learning (ML)-based prediction models in systemic lupus erythematosus (SLE). We made a systematic review of adherence in diagnostic…
  • Abstract Number: 2039 • ACR Convergence 2022

    The Tubarial Glands Resemble the Palatal Salivary Glands Based on Further Histological Characterization, and May Represent an Organ of Interest in Primary Sjögren’s Syndrome

    Sarah Pringle1, Floris Bikker2, Wouter Vogel3, Ingrid Hofland3, Bert van der Vegt4, Hendrika Bootsma1, Frans Kroese1, Arjan Vissink5 and Matthijs Valstar3, 1University Medical Center Groningen, Groningen, Netherlands, 2ACTA, Amsterdam, Netherlands, 3NKI, Amsterdam, Netherlands, 4University Medical Center Groningen, University of Groningen, Groningen, Netherlands, 5UMCG, Leek, Netherlands

    Background/Purpose: Primary Sjögren's syndrome (pSS) often results in dysfunction of the salivary glands (hyposalivation and xerostomia) and substantial decrease in patient quality of life. High…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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