ACR Meeting Abstracts

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  • Abstract Number: 0478 • ACR Convergence 2025

    Racial and Ethnic Disparities in DMARD Use and in Medicare Part B-Covered Options Among Medicare Beneficiaries with Late-Onset Rheumatoid Arthritis

    ashkan ara1, John FitzGerald2 and Susan Ettner2, 1UCLA Health, Los Angeles, CA, 2UCLA, Los Angeles, CA

    Background/Purpose: Biologic and targeted synthetic DMARDs can substantially improve the quality of life for Medicare beneficiaries with rheumatoid arthritis (RA). However, racial and ethnic disparities…
  • Abstract Number: 0421 • ACR Convergence 2025

    Inflammatory Orbital Diseases: Pediatric Case Series From a Tertiary Care Center

    Rasha Elrefai1, Katherine Williams2 and Hannah Bradfield3, 1Baylor College of Medicine, Houston, TX, 2Texas Children's Hospital, Houston, TX, 3Baylor College of Medicine/Texas Children's Hospital, Houston, TX

    Background/Purpose: Orbital inflammatory diseases in the pediatric population present diagnostic and therapeutic challenges due to variable clinical manifestations, limited prospective data, and lack of standardized…
  • Abstract Number: 0395 • ACR Convergence 2025

    Association Between Body Mass Index (BMI) and JIA Inactive Disease at One Year

    Anna Sutton1 and Susan Shenoi2, 1University of Washington, Seattle, WA, 2Seattle Children's Hospital and Research Center, Mercer Island, WA

    Background/Purpose: Among adults, higher BMI contributes to worse outcomes and reduced response to treatment in rheumatoid arthritis (RA), but this relationship is understudied among those…
  • Abstract Number: 0486 • ACR Convergence 2025

    Safety of sarilumab in more than 1000 patients with rheumatoid arthritis in Japan by age group: a post-marketing surveillance study

    Hideto Kameda1, Sadatomo Tasaka2, Toshiya Takahashi3, Naoki Soeda3, Katsuhisa Suzuki4 and Yoshiya Tanaka5, 1Department of Internal Medicine, Toho University, Tokyo, Japan, 2Department of Respiratory Medicine, Hirosaki University Graduate School of Medicine, Hirosaki, Japan, 3Medical Affairs, Asahi Kasei Pharma Corporation, Tokyo, Japan, 4Medical Affairs, Sanofi K.K., Tokyo, Japan, 5University of Occupational and Environmental Health, Japan, Kitakyushu, Japan

    Background/Purpose: Sarilumab (SAR) is approved as monotherapy or in combination with conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) for treatment of patients (pts) with moderate-to-severely active…
  • Abstract Number: 0473 • ACR Convergence 2025

    A Phase 2b Dose-Ranging Study of Peresolimab for Adults with RA

    Jay Tuttle1, Kirstin Griffing2, Mark Genovese2, Hyungmin Rha2, So Young Park2, Pia Yachi1, Ajay Nirula1, LANCE PFEIFER2, Tami Jo Rayle2, Jesus Abraham Simón-Campos3, Clifton Bingham4, Kevin Winthrop5, Daniel Aletaha6, Iain McInnes7, Yu Xue8, Yoshiya Tanaka9, Roy Fleischmann10, Paul Emery11 and Michael Weinblatt12, 1Lilly Biotechnology Center, San Diego, CA, 2Eli Lilly and Company, Indianapolis, IN, 3Köhler & Milstein Research, UADY School of Medicine, Merida, Yucatan, Mexico, 4Johns Hopkins University, Baltimore, MD, 5Oregon Health & Science University, Portland, OR, 6Medical University Vienna, Wien, Austria, 7University of Glasgow, Glasgow, United Kingdom, 8Huashan Hospital, Fudan University, Shanghai, China (People's Republic), 9University of Occupational and Environmental Health, Japan, Kitakyushu, Japan, 10Metroplex Clinical Research Center and University of Texas Southwestern Medical Center, Dallas, TX, 11University of Leeds, Leeds, England, United Kingdom, 12Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Peresolimab, a humanized IgG1 mAb, activates programmed cell death protein 1. In a phase 2a study, peresolimab demonstrated efficacy in participants (pts) with RA…
  • Abstract Number: 0426 • ACR Convergence 2025

    Tofacitinib in Juvenile Idiopathic Arthritis: efficacy and safety in a clinical practice setting.

    Vicenç Torrente-Segarra1, Andrea Zacarias2, Cynthia Rojas3, Jordi Antón-López2, Judith Sanchez4 and Meritxell Salles Lizarzaburu5, 1Hospital Comarcal Alt Penedés Garraf, Vilafranca del Penedès, Spain, 2Pediatric Rheumatology Department, Hospital Sant Joan de Déu, Barcelona (Spain)., Barcelona, Spain, 3Rheumatology Department, Hospital Comarcal Alt Penedès Garraf, Vilafranca del Penedès (Spain)., Vilafranca del Penedes, Spain, 4Pediatric Rheumatology Department, Taulí Hospital Universitari-Institut d'Investigació i Innovació Parc Taulí (I3PT-CERCA), Sabadell (Spain)., Sabadell, Spain, 5Rheumatology Department, Althaia Xarxa Assistencial Universitària Manresa Manresa (Spain)., Manresa, Spain

    Background/Purpose: This study aims to evaluate the efficacy and safety of tofacitnib, a JAK inhibitor, in a multicentric cohort of patients with juvenile idiopathic arthritis…
  • Abstract Number: 0503 • ACR Convergence 2025

    Impact of Olokizumab on Pain in Rheumatoid Arthritis: a Meta-analysis

    Andrey E. Karateev1, Sofia Kuzkina2, Alina Egorova3 and Elena Y. Polishchuk1, 1V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia, 2R-Pharm, Moscow, Russia, 3R-Pharm JSC, Moscow, Russia

    Background/Purpose: Pain is one of the most debilitating symptoms of rheumatoid arthritis (RA) and a major contributor to reduced quality of life. Persistent joint pain…
  • Abstract Number: 0391 • ACR Convergence 2025

    Which score fits best? Correlation of clinical indices of Disease Activity and Ultrasound findings in Juvenile Idiopathic Arthritis during Transitional Care

    Andrea Pilato1, Giusyda Tarantino2, Maria Isabella Petrone2, Angela Aquilani2, Emiliano Marasco2, Rebecca Nicolai2, Fabrizio De Benedetti3, Roberto Giacomelli4, Luca Navarini1 and Silvia Magni-Manzoni2, 1University of Rome Campus Bio-Medico, Rome, Italy, 2Bambino Gesù IRCCS Children's Hospital, Rome, Italy, 3Bambino Gesu Children's Hospital, Rome, Rome, Italy, 4i) Clinical and Research Section of Rheumatology and Clinical Immunology, Fondazione Policlinico Campus Biomedico; ii) Rheumatology and Clinical Immunology, Department of Medicine, School of Medicine, University of Rome "Campus Bio-Medico", Rome, Italy

    Background/Purpose: Monitoring disease activity is a crucial aspect of the treat to target paradigm in the management of rheumatic diseases. There are no standardized protocols…
  • Abstract Number: 0375 • ACR Convergence 2025

    Association of Glucocorticoid Toxicity Index Scores with Quality-of-Life and Healthcare Resource Utilization at 6 Months in a Real-World Cohort of Individuals Receiving Glucocorticoids

    Naomi Patel1, Jiaqi Wang1, Isha Jha2, Grace McMahon1, Tania Chiha3, Hyon K. Choi4 and John Stone5, 1Massachusetts General Hospital, Boston, MA, 2Massachusetts General Hospital, Boston, 3Mount Auburn Hospital, Boston, 4MASSACHUSETTS GENERAL HOSPITAL, Lexington, MA, 5Massachusetts General Hospital , Harvard Medical School, Concord, MA

    Background/Purpose: Glucocorticoids (GCs) are used long-term by approximately 1% of the adult population and contribute to excess morbidity and mortality. We prospectively assessed Glucocorticoid Toxicity…
  • Abstract Number: 0453 • ACR Convergence 2025

    Safety of DMARDs in Rheumatoid Arthritis: A Nationwide Study of ILD Risk and Outcomes in RA-ILD

    kyung-Ann Lee1, Bora Lee2, Hyun-Sook Kim3 and Se Hee Kim4, 1Soonchunhyang University Hospital Seoul: Soonchunhyang University Hospital, Seoul, Republic of Korea, 2Chosun University, GwangJu, Republic of Korea, 3Soonchunhyang University Seoul Hospital, Seoul, Republic of Korea, 4Kyung Hee University College of Medicine, Seoul, Republic of Korea

    Background/Purpose: Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is a potentially life-threatening extra-articular manifestation of RA. The comparative safety of disease-modifying antirheumatic drugs (DMARDs) in RA…
  • Abstract Number: 0427 • ACR Convergence 2025

    Maternal Smoking During Pregnancy and Risk of Juvenile Idiopathic Arthritis (JIA): Triangulating Evidence from Polygenic Risk Scores and Meta-Analysis in Scandinavian Birth Cohorts

    Vilde Øverlien Dåstøl1, Kristine Løkås Haftorn2, Maria Christine Magnus3, Sigrid Hestetun4, Siri Eldevik Håberg5, Lisa Rider6, Karen H. Costenbader7, Ida Henriette Caspersen8, Sjurdur Frodi Olsen9, Ketil Størdal10 and Helga Sanner1, 1Oslo University Hospital, Oslo, Norway, 2Oslo University Hospital, Department of Rheumatology, Oslo, Norway, 3Norwegian Institute of Public Health, Centre for Fertility and Health, Oslo, Norway, 4Oslo University Hospital, Department of Rheumatology/University of Oslo, Oslo, Norway, 5Norwegian Institute of Public Health, Centre for Fertility and Health/University of Bergen, Oslo, Norway, 6National Institute of Environmental Health Sciences/National Institutes of Health, Environmental Autoimmunity Group, Bethesda, MD, 7Harvard Medical School and Brigham and Women's Hospital, Boston, MA, 8Norwegian Institute of Public Health, Centre for Fertility and Health/Oslo University Hospital, Oslo, Norway, 9Statens Serum Institut,Biobank, congenital disorders, and vaccines preparedness/Harvard T.H. Chan School of Public Health, Copenhagen, Denmark, 10Oslo University Hospital, Department of Pediatric and Adolescent Medicine/University of Oslo, Oslo, Norway

    Background/Purpose: Maternal smoking during pregnancy has been associated with a seemingly lower risk of juvenile idiopathic arthritis (JIA) in the child (1), contrasting with smoking’s…
  • Abstract Number: 0468 • ACR Convergence 2025

    Performance of the expanded cardiovascular risk prediction score for rheumatoid arthritis (ERS-RA) in a nationwide multicenter Chinese cohort

    Xingbei Dong1, Nan Jiang2, Hong Li3, Misti Paudel4, Jiangmei Liu5, Xinwang Duan6, Dongmei Wu7, Hongbin Li8, Fen Li9, Yongfu Wang10, Ju Liu11, Shengqian Xu12, Hui Luo13, huanzi dai14, Shuhong Chi15, Jian Xu16, Lijun Wu17, zhaohui zheng18, Jing Xue19, Xiaofu Yu20, QIn Huang21, Xiaofei Shi22, Xiaomin Zhang23, Yuehong Huo24, Qian Wang2, Xiaofeng Zeng25, Daniel Solomon26, Mengtao Li2 and Xinping Tian2, 1Peking Union Medical College Hospital, Beijing, China (People's Republic), 2Peking Union Medical College Hospital, Beijing, Beijing, China (People's Republic), 3Beijing Anzhen Hospital, Capital Medical University, Beijing, China (People's Republic), 4Brigham and Women's Hospital, Division of Rheumatology, Inflammation, and Immunity, Boston, MA, 5Chinese Center for Disease Control and Prevention, Beijing, China (People's Republic), 6The Second Affiliated Hospital of Nanchang University, Nanchang, China (People's Republic), 7The People's Hospital of Yuxi City, Yuxi, China (People's Republic), 8The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China (People's Republic), 9The Second Xiangya Hospital of Central South University, Changsha, China (People's Republic), 10The First Affiliated Hospital of Baotou Medical College, Baotou, China (People's Republic), 11Affiliated Jiujiang Hospital of Nanchang University, Jiujiang, China (People's Republic), 12The First Affiliated Hospital of Anhui Medical University, Hefei, China (People's Republic), 13Xiangya Hospital of Central South University, Changsha, China (People's Republic), 14Daping Hospital & Research Institute of Surgery, Army Medical University, Chongqing, PR China., Chongqing, China (People's Republic), 15General Hospital of Ningxia Medical University, Yinchuan, China (People's Republic), 16The First Affiliated Hospital of Kunming Medical University, Kunming, China (People's Republic), 17People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China (People's Republic), 18Department of Clinical Immunology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China (People's Republic), 19The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China (People's Republic), 20Guyuan People’s Hospital, Guyuan, China (People's Republic), 21Nanfang Hospital, Guangzhou, China (People's Republic), 22The First Affiliated Hospital of Henan University of science and Technology, Luoyang, China (People's Republic), 23Red Flag Hospital Affiliated to Mudanjiang Medical College, Mudanjiang, China (People's Republic), 24The Fifth People's Hospital of Datong, Datong, China (People's Republic), 25Department of Rheumatology, Peking Union Medical College Hospital (PUMCH), Chinese Academy of Medical Sciences National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Beijing, China (People's Republic), 26Brigham and Women's Hospital, Newton, MA

    Background/Purpose: Patients with rheumatoid arthritis (RA) are at increased risk of developing cardiovascular (CV) events compared to the general population. However, this risk is often…
  • Abstract Number: 0455 • ACR Convergence 2025

    Assessment of Pain Outcomes in Pooled Phase 3 Trials of a Selective, Tyrosine Kinase 2 Inhibitor, Deucravacitinib, in Patients With Active Psoriatic Arthritis

    Lihi Eder1, Philip J. Mease2, Vibeke Strand3, Alexis Ogdie4, Atul Deodhar5, Rebecca Haberman6, April Armstrong7, Alice B. Gottlieb8, David Roberts9, Laurie Eliason10, Stefan Varga11, Eleni Vritzali12, Janice Li11 and Laure Gossec13, 1University of Toronto, Toronto, ON, Canada, 2Department of Rheumatology, Providence-Swedish Medical Center and University of Washington, Seattle, WA, 3Stanford University School of Medicine, Palo Alto CA, Portola Valley, CA, 4University of Pennsylvania, Philadelphia, PA, 5Division of Arthritis and Rheumatic Diseases, Oregon Health & Science University, Portland, OR, 6NYU Langone Health, New York, NY, 7University of California Los Angeles, Los Angeles, CA, USA, Los Angeles, CA, 8Department of Dermatology, UT Southwestern Medical Center, Dallas, TX, 9Bristol Myers Squibb, Uxbridge, United Kingdom, 10Bristol Myers Squibb,, Princeton, NJ, 11Bristol Myers Squibb, Princeton, NJ, 12Bristol Myers Squibb, Boudry, Switzerland, 13Sorbonne Universite and Pitie-Salpetriere Hospital, Paris, France

    Background/Purpose: Patients rate pain as one of the most important aspects of psoriatic arthritis (PsA). Pain signaling involves a series of cytokines, including those downstream…
  • Abstract Number: 0505 • ACR Convergence 2025

    Use of Upadacitinib in Real-World Clinical Practice: Patient Characteristics and Glucocorticoid-Sparing Effect

    Virginia Ruiz-Esquide1, Lourdes Mateo2, Carolina Pérez García3, Hye Sang-Park4, Susana Holgado5, María Aparicio6, Beatriz Frade7, Juan Camilo Sarmiento-Monroy8, Annika Nack9, Felipe Julio Ramirez Garcia10, José Gomez-Puerta11 and Raimon Sanmartí1, 1Hospital Clínic de Barcelona, Barcelona, Catalonia, Spain, 2Hospital Trías i Pujol, Barcelona, Catalonia, Spain, 3Hospital del Mar, Barcelona, Spain, 4Hospital Santa Creu i Sant Pau, Barcelona, Catalonia, Spain, 5Hospital Germans Trias i Pujol, Barcelona, Catalonia, Spain, 6Hospital Germans Trías i Pujol, Badalona, Catalonia, Spain, 7Hospotal Clínic de Barcelona, Barcelona, Catalonia, Spain, 8Hospital Clínic Barcelona, Barcelona, Spain, 9Hospital Germans Trias i Pujol, Barcelona, Spain, 10Rheumatology Department, Hospital Clinic and IDIBAPS of Barcelona, Barcelona, Spain, 11Rheumatology Department, Hospital Clinic, Barcelona, Spain, Barcelona, Spain

    Background/Purpose: While clinical trials have demonstrated the efficacy of upadacitinib (UPA), real-world data are essential to understand patient characteristics and assess its effectiveness in routine…
  • Abstract Number: 0464 • ACR Convergence 2025

    Synovial Inflammation is not Associated With Reoperation in Patients With Rheumatoid Arthritis Undergoing Total Hip or Knee Arthroplasty

    Solana Cushing1, Kelsey Gripp2, Edward DiCarlo3, Deanna Jannat-Khah1, Yoshimi Endo3, Jose Rodriguez3, Mark Figgie3, Bella Mehta4 and Susan Goodman3, 1Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, New York, 3Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 4Hospital for Special Surgery, Weill Cornell Medicine, Jersey City, NJ

    Background/Purpose: Reoperations following arthroplasty are a significant burden to patients and surgeons. In patients with RA who receive total hip (THA) or knee (TKA) arthroplasty,…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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