ACR Meeting Abstracts

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  • Abstract Number: 0267 • ACR Convergence 2024

    IL-17 Participates in the Pathogenesis of Chronic Gouty Arthritis

    Hong Di1, Xinxin Han1, Yun Zhang2 and Xuejun Zeng1, 1Peking Union Medical College Hospital, Beijing, China, 2Peking Union Medical College Hospital (CAMS), Beijing, China

    Background/Purpose: Chronic gouty arthritis (CGA) is different from acute gouty arthritis  (AGA), its main characteristics include repeated or even persistent joint symptoms, tophus and bone destruction.…
  • Abstract Number: 0334 • ACR Convergence 2024

    Normal Creatine Kinase in Idiopathic Inflammatory Myopathies- Patient Characteristics and Disease Activity

    shiri keret1, Tanya Chandra2, Lisa Kaly3, Raisa Silva4, Eugenia Gkiaouraki5, Nantakarn Pongtarakulpanit6, shreya Sriram5, Rajesh Gopalarathinam7, Siamak Mogahadam6, Chester Oddis6 and Rohit Aggarwal8, 1Rheumatology unit, Bnai-Zion medical center and the faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel., Atlit, Israel, 2University of Pittsburgh Medical Center, Pittsburgh, PA, 3Rheumatology unit, Bnai-Zion medical center and the faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel., Haifa, Israel, 4Internal medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, 5Division of Rheumatology and Clinical Immunology, University of Pittsburgh Medical Center, Pittsburgh, PA, 6Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 7Division of Rheumatology, Wrightington Wigan and Leigh Teaching Hospitals NHS Foundation Trust, Wigan, United Kingdom, 8Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, PA

    Background/Purpose: Creatine kinase (CK) is an important biomarker for the diagnosis and monitoring of Idiopathic Inflammatory Myopathies (IIM). However, in some cases, CK levels might…
  • Abstract Number: 0321 • ACR Convergence 2024

    Diffusion Weighted Imaging in Muscle MRI Can Detect Quantitative Improvements in Muscle Edema: A Post-hoc Analyses of the Study of Tofacitinib in Refractory Dermatomyositis

    Julie Paik1, Patrick Debs2, Anshula Nallapati1, Lisa Christopher-Stine1, Jemima Albayda3, Eleni Tiniakou4 and Laura Fayad2, 1Johns Hopkins University, Baltimore, MD, 2Johns Hopkins Radiology, Baltimore, MD, 3Johns Hopkins School of Medicine, Baltimore, MD, 4Johns Hopkins University, Lutherville Timonium, MD

    Background/Purpose: Diffusion weighted imaging (DWI) in muscle magnetic resonance imaging is an underutilized, quantitative assessment tool in idiopathic inflammatory myopathies (IIM). It is not uncommon…
  • Abstract Number: 0284 • ACR Convergence 2024

    Identification of Calcium Pyrophosphate Deposition Using Ultrasonography in Patients with a Suspected Diagnosis of Seronegative Rheumatoid Arthritis

    Joanna Potera1, Angelo Gaffo2, Alvin Day3, Mariana Urquiaga2 and Amanda Alexander4, 1University of Alabama at Birmingham, Irondale, AL, 2University of Alabama at Birmingham, Birmingham, AL, 3Dept. of Veterans Affairs, Lexington, SC, 4University of Alabama at Birmingham, Homewood, AL

    Background/Purpose: Calcium pyrophosphate deposition disease is a common condition that can cause chronic polyarticular inflammatory joint disease, which sometimes resembles rheumatoid arthritis. Misdiagnosis is especially…
  • Abstract Number: 0292 • ACR Convergence 2024

    Liver Disease Complicating Familial Mediterranean Fever: A Study on 57 Patients from the French Adult JIR Cohort

    Marion Delplanque1, xavier amiot2, Dominique Wendum3, françois Rodrigues2, Rim bourguiba1, Benoit Terris4, Christophe Duvoux2, Pierre Bedossa5, Didier lebrec5, Philippe Sogni2, Lucia parlati2, Frederic Charlotte2, Vlad Ratziu2, stephane mouly6, jeremy augustin2, julien Calderaro2, giovana scoazec2, JM Vignaud7, JA Seyrig8, Gilles Grateau1, Lea Savey9 and Sophie Georgin-lavialle10, 1Internal Medicine Department, Tenon Hospital, AP-HP, Paris, France, Paris, France, 2APHP, Paris, 3APHP, Paris, France, 4Department of pathology, Hôpital Cochin, GHU Paris Centre, AP-HP, Université Paris Cité,, Paris, France, 5APHP, clichy, 6Department of internal medicine, Centre de Compétence Maladies Rares autoimmunes et inflammatoires, Lariboisière Hospital, Université Paris Cité, Paris, Ile-de-France, France, 7CHRU nancy, Nancy, 8CH centre bretagne, pontivy, 9Internal Medicine Department, Tenon Hospital, AP-HP, Paris, France, france, France, 10Sorbonne Université, Department of internal medicine, Tenon Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France

    Background/Purpose: Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease, associated with MEFV gene mutations. FMF patients can experience liver involvement, potentially leading…
  • Abstract Number: 0557 • ACR Convergence 2024

    What Factors Are Associated with Pain Intensity in Axial Spondyloarthritis? Results from the International Map of Axial Spondyloarthritis (IMAS)

    Marco Garrido-Cumbrera1, Victoria Navarro Compán2, Fernando Andres Sommerfleck3, Christine Bundy4, Souzi Makri5, José Correa-Fernández6, Shashank Akerkar7, Jo Lowe8, Elie Karam9 and Denis Poddubnyy10, 1Health & Territory Research (HTR), Universidad de Sevilla, Seville, Spain / Spanish Federation of Spondyloarthritis Patient Associations (CEADE), Madrid, Spain, Seville, Spain, 2La Paz University Hospital, Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain, 3Sanatorio Julio Mendez, Buenos Aires, Argentina, 4Cardiff University, Cardiff, UK, Cardiff, United Kingdom, 5Cyprus League for People with Rheumatism (CYLPER), Nicosia, Cyprus, Nicosia, Cyprus, 6Health & Territory Research (HTR), Universidad de Sevilla, Seville, Spain, Seville, Spain, 7Mumbai Arthritis Clinic, Mumbai, India, Mumbai, India, 8Axial Spondyloarthritis International Federation, London, United Kingdom, 9Canadian Spondylitis Association (CSA), Toronto, Canada, Toronto, Canada, 10Charite-Universitatsmedizin Berlin, Berlin, Germany

    Background/Purpose: Severe pain in patients with axial spondyloarthritis (axSpA) can cause deterioration in their physical and mental health. The aim is to investigate factors associated…
  • Abstract Number: 0014 • ACR Convergence 2024

    Phenotypic Validation of Humanized IgA1 and CD89 Transgenic Mice as a Model for IgA Nephropathy-Like Autoimmune Disease

    Kaiyuan Zi and Juan Liang, GemPharmatech, San Diego

    Background/Purpose: The etiology of IgA nephropathy (IgAN) remains only partly understood, but the presence of IgA antibodies together with the myeloid IgA-receptor FcαRI/CD89 complexes in…
  • Abstract Number: 0224 • ACR Convergence 2024

    How Accurate Are Assessments by Local Radiologists of Sacroiliac Joint MRIs in Axial Spondyloarthritis and Psoriatic Arthritis in Routine Clinical Practice?- Evidence from 873 Patients in Five European Countries

    Anna EF Hadsbjerg1, Simon Krabbe2, Nora Vladimirova2, Adrian Ciurea3, Kristyna Bubova4, Monika Gregová4, Michael Nissen5, Burkhard Moeller6, Raphael Micheroli7, Susanne Pedersen8, Jakub Zavada4, Ziga Snoj9, Karlo Pintaric9, Bjorn Gudbjornsson10, Ziga Rotar11, iris Eshed12, Iwona Sudol-Szopinska13, Kasper Gosvig14, Torsten Diekhoff15, Robert Lambert16, Manouk de hOoge17, Helena V G Elmo1, Merete Hetland18, Lykke Oernbjerg19 and Mikkel Ostergaard20, 1Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Righospitalet, Glostrup, Denmark, 2Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Righospitalet, Copenhagen, Denmark, 3University Hospital Zurich, Zürich, Switzerland, 4Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine Charles University, Prague, Czech Republic, 5Geneva University Hospital, Geneva, Switzerland, 6Inselspital - University Hospital Bern, Bern, Switzerland, 7University Hospital Zurich, Zurich, Switzerland, 8Rigshospitalet, København, Denmark, 9Institute of Radiology, UMC Ljubljana, Ljubljana, Slovenia, 10Landspitali University Hospital and University of Iceland, Reykjavik, Iceland, 11University Medical Centre Ljubljana and University of Ljubljana, Ljubljana, Slovenia, 12Sheba Medical Center, Tel Hashomer affiliated with School of medicine, Tel Aviv University, Department of Diagnostic Imaging, Tel Aviv, Israel, 13Department of Radiology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland, 14Department of Radiology, Copenhagen University Hospital Herlev-Gentofte, Herlev, Denmark, 15Charite Universitatsmedizin Berlin, Berlin, Germany, 16University of Alberta, Edmonton, AB, Canada, 17Dept. of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium, 18Rigshospitalet Glostrup and University of Copenhagen, Glostrup, Denmark, 19Rigshospitalet Glostrup, Glostrup, Hovedstaden, Denmark, 20Department of Clinical Medicine, University of Copenhagen and Center for Rheumatology, Copenhagen Center for Arthritis Research, Glostrup, Denmark

    Background/Purpose: MRI of the sacroiliac joints (SIJs) is widely used for diagnosing and monitoring patients with spondyloarthritis (SpA). However, local radiologists might be less familiar with…
  • Abstract Number: 0368 • ACR Convergence 2024

    Development and Validation of a Patient-centered Self-evaluation Questionnaire in Systemic Lupus Erythematosus: LUPIN®

    Marc Scherlinger1, Jean-Francois Kleinmann1, Antonin Folliasson2, Marianne Riviere3, Raphaelle Rybak4, Sabine Malivoir5, Jean-François Viallard6, Estibaliz Lazaro7, Christophe Richez8, Irene Machelart9, Nadine Magy-Bertrand10, Audrey Gorse11, Gilles Blaison12, Julien Campagne13, Benjamin Dervieux14, Thomas Moulinet15, Roland Jaussaud16, Pascal Roblot17, Mathieu Puyade17, Amélie Servettaz18, Pauline Orquevaux18, Julie le Scanff19, DANIEL WENDLING20, Marc Andre21, Ludovic Trefond21, Perrine SMETS22, Nicolas Baillet23, Christophe Deligny24, Xavier Mariette25, ARNAUD HOT26, Emmanuelle David27, Laurent Perard28, Estelle Jean29, Sarah Permal30, Denis WAHL31, Christian Agard32, François Chasset33, Baptiste Hervier34, Pasquer Ronan2, Mickael Martin17, Ludivine Lebourg35, Frederic Renou36, Loic Raffray36, Elisabeth Diot37, Cecile Fermont38, Thierry Martin39, Anne-Sophie Korganow39, Jacques-Eric Gottenberg40, Jean Sibilia41 and Zahir Amoura42, 1Strasbourg University Hospital - National reference center for autoimmune disease, Rheumatology, Strasbourg, France, 2Hometrix Health, Paris, France, 3Association Francaise du Lupus et autres maladies autoimmunes (AFL+), Metz, France, 4Association Francaise du Lupus et autres maladies autoimmunes (AFL+), Paris, France, 5APHP Pitié Salpêtrière - National reference center for autoimmune disease, Internal Medicine, Paris, France, 6CHU de Bordeaux, Hôpital Haut-Lévêque, Pessac, FR, Bordeaux, France, 7Bordeaux University Hospital, Pessac, France, 8Université de Bordeaux, Bordeaux, France, 9CH de Bayonne - Competence center for autoimmune diseases, Internal Medicine, Bayonne, France, 10CHU de Besancon - Competence center for autoimmune diseases, Internal Medicine, Besançon, France, 11CH de Chambery - Competence center for autoimmune diseases, Internal Medicine, Chambery, France, 12CH de Colmar - Competence center for autoimmune diseases, Internal Medicine, Colmar, France, 13Hôpital Robert Schuman - Competence center for autoimmune diseases, Internal Medicine, Metz, France, 14CH de Mulhouse - Competence center for autoimmune diseases, Internal Medicine, Mulhouse, France, 15CHRU de Nancy, Vandœuvre-lès-Nancy, France, 16CHU de Nancy - Competence center for autoimmune diseases, Internal Medicine, Nancy, France, 17CHU de Poitiers - Competence center for autoimmune diseases, Internal Medicine, Poitiers, France, 18CHU de Reims - Competence center for autoimmune diseases, Internal Medicine, Reims, France, 19CH - Competence center for autoimmune diseases, Internal Medicine, Villefranche-sur-Saone, France, 20University Hospital, Besançon, France, 21CHU de Clermont-Ferrand - National reference center for autoimmune disease, Internal Medicine, Clermont-Ferrand, France, 22Clermont Ferrand University Hospital - National reference center for autoimmune disease, Internal Medicine, Clermont-Ferrand, France, 23CH de Basse-Terre - Competence center for autoimmune diseases, Internal Medicine, Basse-Terre, France, 24University Hospital of Martinique - National reference center for autoimmune disease, Internal Medicine, Fort-de-France, Martinique, 25Service de Rhumatologie, Hôpital Bicêtre, AP-HP, Le Kremlin Bicetre, France, 26Service de Médecine interne, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France, 27HCL - Croix Rousse, Internal Medicine, Lyon, France, 28Hopital Saint-Joseph, Internal Medicine, Lyon, France, 29APHM - La Timone, Internal Medicine, Marseille, France, 30CH Mayotte - CH Wallis-et-Futuna, Internal Medicine, Mamoudzou, Mayotte, 31Lorraine University, Nancy, France, 32CHU de Nantes - National reference center for autoimmune disease, Internal Medicine, Nantes, France, 33Dermatology, Hôpital Tenon, Paris, France, 34APHP Saint-Louis - National reference center for autoimmune disease, Internal Medicine, Paris, France, 35CHU de Rouen, Internal Medicine, Rouen, France, 36CHU La Réunion - Competence center for autoimmune diseases, Internal Medicine, Saint-Denis, Reunion, 37CHU de Tours - Competence center for autoimmune diseases, Internal Medicine, Tours, France, 38CH de Valence - Competence center for autoimmune diseases, Internal Medicine, Valence, France, 39Strasbourg University Hospital, National reference center for autoimmune disease, Clinical Immunology, Strasbourg, France, 40Rheumatology Department, Strasbourg University Hospital,, Strasbourg, France, 41Strasbourg University Hospital, National reference center for autoimmune disease, Rheumatology, Strasbourg, France, 42French National Reference Centre for Systemic Lupus Erythematosus, Pitié-Salpêtrière Hospital, Paris, France

    Background/Purpose: Systemic Lupus Erythematosus (SLE) features unpredictable disease activity fluctuations, making flare hard to detect and significantly impairing quality of life. This highlights the need…
  • Abstract Number: 0388 • ACR Convergence 2024

    The Association Between Body Composition and Disease and Treatment Outcomes in Patients with Juvenile Idiopathic Arthritis: Results from the CAPRI Registry

    Samantha Morin1, KAREN BEATTIE2, Roxana Bolaria3, Tania Cellucci4, Gaelle Chedeville5, Amieleena Chhabra6, Paul Dancey7, Tommy Gerschman8, Liane Heale9, Julie Herrington2, Adam Huber10, Mehul Jariwala11, Jean-Philippe Proulx-Gauthier12, Dax Rumsey13, Heinrike Schmeling14, Jaime Guzman15 and Michelle Batthish4, and CAPRI Registry Investigators, 1McMaster University, Hamilton, Canada, 2McMaster University, Hamilton, ON, Canada, 3Victoria Arthritis Center, Victoria, BC, Canada, 4McMaster Children's Hospital, Hamilton, ON, Canada, 5The Montreal Children's Hospital, Montreal, QC, Canada, 6University of British Columbia, Penticton, BC, Canada, 7Memorial University, St. John's, Canada, 8University of British Columbia - Vancouver, North Vancouver, BC, Canada, 9McMaster University, Oakville, ON, Canada, 10IWK Health Centre, Halifax, NS, Canada, 11Jim Pattison Children's Hospital, Saskatoon, Canada, 12CHU de Quebec - Universite Laval, Quebec, QC, Canada, 13University of Alberta, Edmonton, AB, Canada, 14University of Calgary, Calgary, AB, Canada, 15University of British Columbia and BC Children's Hospital, Vancouver, BC, Canada

    Background/Purpose: Recent evidence has linked abnormal body weight, underweight or obesity, with poor disease outcomes in adults with inflammatory arthritis. Yet, little is known about…
  • Abstract Number: 0375 • ACR Convergence 2024

    Patient Outcomes During the Implementation of a Patient Decision-Aid for a Diverse Population of Systemic Lupus Erythematosus: A Study in 15 U.S. Rheumatology Clinics

    Jasvinder Singh1, Larry Hearld2, Walter Chatham3, Sonali Narain4, Narender Annapureddy5, Diane Kamen6, Kimberly Trotter7, vikas Majithia8, Zineb Aouhab9, Swamy Venuturupalli10, Daniel Wallace11, rosalind Ramsey-Goldman12, Alfred Kim13, Maureen McMahon14, S. Sam Lim15, Kalpana Bhairavarasu16, Alexa Meara17, Kenneth Kalunian18 and Cathy Lee Ching19, 1Baylor College of Medicine, Birmingham, AL, 2University of Alabama at Birmingham (UAB), Birmingham, AL, 3University of Nevada, Las Vegas, Las Vegas, NV, 4Northwell Health, Great Neck, NY, 5Vanderbilt University Medical Center, Nashville, TN, 6Medical University of South Carolina, Charleston, SC, 7University of Chicago, Chicago, IL, 8University of Missisippi Medical Center (UMC), Jackson, MS, 9Loyola University Medical Center, Oak Brook, IL, 10Attune Health, Beverly Hills, CA, 11Cedars Sinai Medical Center, Studio City, CA, 12Northwestern University, Chicago, IL, 13Washington University School of Medicine, Division of Rheumatology, Department of Medicine, St Louis, MO, 14UCLA David Geffen School of Medicine, Los Angeles, CA, 15Emory University, Atlanta, GA, 16Baylor College of Medicine, Sugar Land, TX, 17The Ohio State University Wexner Medical Center, COLUMBUS, OH, 18University of California San Diego, La Jolla, CA, 19UMMC, Jackson, MS

    Background/Purpose: To implement a self-administered patient decision-aid (PtDA) for lupus in outpatient clinics, assess its reach/penetration within each clinic, and examine patient outcomesMethods: An effective…
  • Abstract Number: 0318 • ACR Convergence 2024

    The Relevance of a Positive ANA in New Patient Referrals to Rheumatology

    Chi Chi Lau1 and Ayesha Arif2, 1University of Vermont Medical Center, colchester, VT, 2University of Vermont Medical Center, Essex Junction, VT

    Background/Purpose: A positive (+)ANA titer is a common reason for Rheumatology consultation, yet the ANA is a nonspecific, non-diagnostic, lab test that is positive in…
  • Abstract Number: 0326 • ACR Convergence 2024

    Validity and Responsiveness of Core Set Measures in Idiopathic Inflammatory Myositis Based on 36-item Short Form Health Survey (SF-36)

    Maha Almackenzie1, Anushka Aggarwal2, shiri keret3, shreya Sriram4, Tanya Chandra5, Raisa Silva6, Eugenia Gkiaouraki4, Siamak Mogahadam7, Chester Oddis7 and Rohit Aggarwal8, 1Division of Rheumatology, Department of Medicine, Medical Cities of the Ministry of the Interior Riyadh, Saudi Arabia, Arlington, VA, 2Department of Rheumatology, Indraprastha Apollo Hospital, New delhi, NY, 3Rheumatology unit, Bnai-Zion medical center and the faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel., Atlit, Israel, 4Division of Rheumatology and Clinical Immunology, University of Pittsburgh Medical Center, Pittsburgh, PA, 5University of Pittsburgh Medical Center, Pittsburgh, PA, 6Internal medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, 7Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 8Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, PA

    Background/Purpose: There are six core set measures (CSMs) of disease activity in patients with idiopathic inflammatory myopathies (IIM). However, there is limited data on their…
  • Abstract Number: 0336 • ACR Convergence 2024

    Mortality: Comparison, Causes and Determinants in Subgroups of Idiopathic Inflammatory Myopathies

    Aurore Larrauffie1, Chloé Bost1, Marie Faruch1, Elisabeth Uro-coste1, Grégoire Prevot1, Thomas Villeneuve1, Jérémy Zordan1, Claire Barrier1, Morgane Mourguet2, Marie Guille1, Laurent Sailler1, Laurent Alric1, Sébastien De Almeida Chaves1 and Grégory Pugnet3, 1CHU Toulouse, Toulouse, France, 2service de médecine interne CHU Toulouse RANGUEIL, Toulouse, France, 3Toulouse Rangueil University Hospital, Toulouse, France

    Background/Purpose: Idiopathic Inflammatory Myopathies (IIMs) are a group of heterogeneous connective tissue diseases including dermatomyositis (DM), polymyositis (PM), anti-synthetase syndromes (ASS), immune-mediated necrotizing myopathies (NM),…
  • Abstract Number: 0323 • ACR Convergence 2024

    Pain Prevalence and Factors Associated with Pain Levels in Patients with Idiopathic Inflammatory Myopathies

    Didem Saygin1, Anne-Marie Malfait2, Kristin Wipfler3, Christopher G McKennan4, Jiaxuan Duan4, Kaleb Michaud5 and Yvonne Lee6, 1Rush University Medical Center, Chicago, IL, 2Rush University Medical Center, Division of Rheumatology, Chicago, IL, 3FORWARD, The National Databank for Rheumatic Diseases, Omaha, NE, 4University of Pittsburgh, Department of Statistics, Pittsburgh, PA, 5University of Nebraska Medical Center, Omaha, NE, 6Northwestern University, Chicago, IL

    Background/Purpose: The cardinal symptom of idiopathic inflammatory myopathies (IIM) is muscle weakness leading to functional limitations in the majority of the patients. With a shift…
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