ACR Meeting Abstracts

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  • Abstract Number: 1304 • ACR Convergence 2022

    Glucocorticoids Affect Bone Mass and Strength by Inhibiting Osteoprogenitor Cell Maturation

    Thomas Ambrosi1, Mathew Murphy1, Charles KF Chan1 and Nancy Lane2, 1Stanford University, Stanford, CA, 2University of California Davis, Hillsborough, CA

    Background/Purpose: Glucocorticoid (GC) induced osteoporosis remains a significant health issue. While GCs are known to reduce bone formation and bone mass, patients treated with GCs…
  • Abstract Number: 1305 • ACR Convergence 2022

    Characterizing Bone Microarchitecture with MRI in Patients with Systemic Lupus Erythematosus

    Joshua Novack1, Gregory Chang2, Stephen Honig1, Anmol Monga2, Xiaoliu Zhang3, Punam Saha3, Dimitri Martel2, Peter Izmirly4, H Michael Belmont5, Jill Buyon4 and Amit Saxena5, 1NYU Langone Health Department of Medicine, New York, NY, 2NYU Langone Health Department of Radiology, New York, NY, 3University of Iowa Departments of Radiology and Electrical and Computer Engineering, Iowa City, IA, 4NYU Grossman School of Medicine, New York, NY, 5NYU School of Medicine, New York, NY

    Background/Purpose: Fractures in patients with systemic lupus erythematosus (SLE) are more common than age and sex matched controls. Fracture risk is traditionally assessed by dual-energy…
  • Abstract Number: 1308 • ACR Convergence 2022

    Prevalence and Therapeutic Practices of Osteoporosis in Sarcoidosis in the United States: A Nationwide Registry Study

    Diala Alawneh1, Moustafa Younis2, Romesa Hassan1, Bashar Alzghoul2, Shiva Arami1, Tricha Shivas3, Mary McGowan3, Khaldoon Alawneh4, Christian Ascoli1 and Nadera Sweiss1, 1University of Illinois at Chicago, Chicago, IL, 2University of Florida, Gainesville, FL, 3Foundation for Sarcoidosis Research, Chicago, IL, 4Jordan University of Science and Technology, Irbid, Jordan

    Background/Purpose: Patients with sarcoidosis are at an increased risk of developing osteoporosis due to the active inflammatory state and chronic corticosteroid use. Proper dosing of…
  • Abstract Number: 1307 • ACR Convergence 2022

    Effect of Romosozumab in Postmenopausal Women with Knee Osteoarthritis: Results from the FRAME Clinical Trial

    Nancy Lane1, Donald Betah2, Cynthia Deignan2, Mary Oates2, Zhenxun Wang2, Jen Timoshenko3, Aliya Khan4 and Neil Binkley5, 1University of California Davis, Hillsborough, CA, 2Amgen, Inc., Thousand Oaks, CA, 3UCB Pharma, Slough, United Kingdom, 4McMaster University, Oakville, ON, Canada, 5University of Wisconsin, Madison, WI

    Background/Purpose: Osteoarthritis (OA) and osteoporosis (OP) often occur concomitantly in the elderly. The relationship between OA and OP is complex, with increased fracture risk reported…
  • Abstract Number: 1286 • ACR Convergence 2022

    Increasing Biosimilar Uptake in the Rheumatology Clinics Within a Large Academic Medical Center

    Joad Eseddi1, DeAnne Carmichael2, Shannon Wishin3 and Puneet Bajaj2, 1UT Southwestern School of Medicine, Dallas, TX, 2UT Southwestern Medical Center, Dallas, TX, 3UT Southwestern Medical Centre, Dallas, TX

    Background/Purpose: Biological drugs have revolutionized the treatment of rheumatic diseases. However, increasing the use of biologics over the past few years has directly contributed towards…
  • Abstract Number: 1297 • ACR Convergence 2022

    A Paediatric-Adult Provider Dyad Care Model Improves Transition from Paediatric to Adult Health Care for Youth with Childhood-Onset Systemic Lupus Erythematosus

    Tala El Tal1, Abdulaziz el Mutairi1, Amanda Steiman2 and Earl Silverman3, 1The Hospital for Sick Children, Division of Rheumatology, Department of Paediatrics, University of Toronto, Toronto, ON, Canada, 2Sinai Health System, Toronto, ON, Canada, 3The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada

    Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic multi-system autoimmune disease affecting 1 in 1000 individuals, of whom 20% develop the disease in childhood. Childhood-onset…
  • Abstract Number: 1312 • ACR Convergence 2022

    Cost-Effectiveness of Sequential Treatment with Abaloparatide Followed by Alendronate in US Men at High Risk of Fracture

    Mickael Hiligsmann1, Stuart Silverman2, Andrea J Singer3, Leny Pearman4, jake Mathew4, Yamei Wang4, John Caminis4 and Jean-Yves Reginster5, 1Maastricht University, Maastricht, Netherlands, 2Cedar-Sinai Medical Center and UCLA School of Medicine, Los Angeles, CA, 3MedStar Georgetown University Hospital, Washington, DC, 4Radius Health, Inc., Waltham, MA, 5University of Liège, Liège, Belgium

    Background/Purpose: Previous cost-effectiveness analyses in postmenopausal women (PmW) with osteoporosis (OP) demonstrated that sequential treatment with abaloparatide (ABL) followed by alendronate (ALN) resulted in lower…
  • Abstract Number: 1310 • ACR Convergence 2022

    Is the Trabecular Bone Score (TBS) a Useful Tool in Patients with Diffuse Idiopathic Skeletal Hyperostosis (DISH)?

    Bjoern Buehring1, David Kiefer2, Celina Mueller2, Roshnak Parvaee2, Marianti Ifanti2, Ioana Andreica3, Timm Westhoff4, Rainer Wirth4, Xenofon Baraliakos5, Nina Babel4 and Juergen Braun2, 1Bergisches Rheuma-Zentrum, Wuppertal, Germany, 2Rheumazentrum Ruhrgebiet, Herne, Germany, 3Rheumazentrum Ruhrgebiet, Ruhr-Universität-Bochum, Herne, Germany, 4Marienhospital Herne, Ruhr-University Bochum, Herne, Germany, 5Rheumazentrum Ruhrgebiet Herne, Herne, Germany

    Background/Purpose: Patients with rheumatic and musculoskeletal diseases (RMD) have an increased fracture risk (FxR). Diffuse idiopathic skeletal hyperostosis (DISH) is a non-inflammatory disease characterized by…
  • Abstract Number: 1306 • ACR Convergence 2022

    Improving Osteoporosis Screening in Individuals of Color

    Megan Brochu1, Kristofer Marcus1, Sarah Latorre1, Francis Wanjau1, Arvin Garg2, Eric Alper2, Rulan Lyu1, Tracey Wilkie1 and Jonathan Cheah3, 1UMass Memorial Health, Worcester, MA, 2UMass Memorial Health, UMass Chan Medical School, Worcester, MA, 3UMass Chan Medical School, Worcester, MA

    Background/Purpose: Osteoporosis, including the clinical event of fragility fracture is an ever-increasing public health burden. Effective screening techniques and well as therapies to reduce future…
  • Abstract Number: 1257 • ACR Convergence 2022

    Assessing the Effectiveness of Tocilizumab in Giant Cell Arteritis by PET: Multicenter Study of 101 Patients of Clinical Practice

    Julio Sánchez-Martín1, Javier Loricera1, Santos Castañeda2, Clara Moriano3, F. Javier Narváez4, Vicente Aldasoro5, Olga Maiz6, Rafael Melero7, Juan Ignacio Villa Blanco8, Paloma Vela-Casampere9, Susana Romero Yuste10, José Luis Callejas11, Eugenio De Miguel12, Eva Galíndez-Agirregoikoa13, Francisca Sivera14, Jesus Fernandez15, Carles Galisteo16, Ivan Ferraz Amaro17, Lara Sánchez-Bilbao1, Monica Calderon-Goercke18, Miguel Ángel González-Gay19 and Ricardo Blanco20, 1Hospital Universitario Marqués de Valdecilla, Santander, Spain, 2Division of Rheumatology, Hospital Universitario de La Princesa, IIS-Princesa, Madrid, Spain, 3Complejo Asistencial Universitario de León, León, Spain, 4Rheumatology Department, Hospital Universitario de Bellvitge, Barcelona, Spain, 5Hospital Universitario de Navarra, Pamplona, Spain, 6Hospital Universitario de Donostia, San Sebastián, Spain, 7Complexo Hospitalario Universitario de Vigo, Vigo, Spain, 8Sierrallana Hospital, Torrelavega, Spain, 9Hospital General Universitario Alicante, Alicante, Spain, 10Complexo Hospitalario Universitario, Pontevedra, Spain, 11Hospital San Cecilio, Granada, Spain, 12Hospital Universitario La Paz, Madrid, Spain, 13Basurto University Hospital, Bilbao, Spain, 14Hospital Universitario de Elda, San Vicente del Raspeig, Spain, 15Hospital de La Coruña, La Coruña, Spain, 16Hospital Parc Tauli,, Sabadel, Spain, 17Division of Rheumatology. Hospital Universitario de Canarias. Spain., Santa Cruz de Tenerife, Spain, 18Hospital de Sierrallana, Torrelavega, Spain, 19Department of Medicine and Psychiatry, Universidad de Cantabria; Rheumatology Division, Hospital Universitario Marqués de Valdecilla; Research group on genetic epidemiology and atherosclerosis in systemic diseases and in metabolic diseases of the musculoskeletal system, IDIVAL, Santander, Spain. Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, 20Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain

    Background/Purpose: Positron emission tomography (PET) is one of the tools available for the diagnosis of extracranial large-vessel vasculitis (1-5). Tocilizumab (TCZ) has shown efficacy in…
  • Abstract Number: 1289 • ACR Convergence 2022

    Evaluating Peri–operative Preferences of Bariatric Surgeons in the Management of Immunosuppressive Therapy During Bariatric Surgery

    Suguni Aushadhi Loku Galappaththy1 and Nicole Fearing2, 1University of Missouri Kansas City, Kansas City, MO, 2HCA Menorah Medical Center, Overland Park, KS

    Background/Purpose: As the number of bariatric procedures increases, surgeons will encounter more patients on long-term immunosuppressive medications that may increase post-operative complications. Currently, there are…
  • Abstract Number: 1302 • ACR Convergence 2022

    Assessment of the Transition of Care from Pediatric to Adult Rheumatology in a Tertiary Center

    Serdal Ugurlu1, Ali Yagiz Ayla1, Helin Idil Besiroglu2, Feyza Nur Azman1, Bugra Egeli3, Hatice Eren1, Ibrahim Durucan2, Arif Alkan2, Sila Ozturk1, Sercan Ergun1, Amra Adrovic Yildiz4, Kenan Barut5, Fatih Haslak1, Sezgin Sahin1, Mehmet YILDIZ1, Huri Ozdogan6 and Ozgur Kasapcopur7, 1Istanbul University-Cerrahpaşa, Istanbul, Turkey, 2Istanbul University-Cerrahpaşa Medical Faculty, Istanbul, Turkey, 3Children's Hospital of Los Angeles, Los Angeles, CA, 4School of Medicine, KOC University, Istanbul, Turkey, 5Istanbul University-Cerrahpasa, Istanbul, Turkey, 6Istanbul University-Cerrahpaşa Medical Faculty Department of Internal Medicine Division of Rheumatology, Istanbul, Turkey, 7Istanbul University-Cerrahpaşa, Cerrahpaşa Medical School, Istanbul, Turkey

    Background/Purpose: Taking the responsibility for their own health should be an important goal for the patients in the health care transition process. The Transition Readiness…
  • Abstract Number: 1266 • ACR Convergence 2022

    Time-course Ultrasonography to Predict Flare After Discontinuation of Biologics in Patients with Rheumatoid Arthritis Achieving Stringent Remission

    Takehisa Ogura1, Takaharu Katagiri2, Yuto Takakura3, Chihiro Imaizumi4 and Hideto Kameda4, 1Toho university, Meguro-ku, Japan, 2Toho University School of Medicine (Ohashi Medical Center), Division of Rheumatology, Department of Internal Medicine, Tokyo, Japan, 3Toho University, Setagayaku, Japan, 4Toho University, Tokyo, Japan

    Background/Purpose: Ultrasonography (US) has been suggested to be useful in predicting flare in patients with rheumatoid arthritis (RA) after discontinuation of biological disease-modifying antirheumatic drugs…
  • Abstract Number: 1298 • ACR Convergence 2022

    Pediatric Rheumatology Care and Outcomes Improvement Network Demonstrates Outcome Improvement for Children with Juvenile Idiopathic Arthritis

    Catherine Bingham1, Julia Harris2, Sheetal Vora3, Mileka Gilbert4, Cagri Yildirim-Toruner5, Kerry Ferraro6, Tingting Qiu7, Jon Burnham8, Michelle Batthish9, Beth Gottlieb10, Daniel Lovell7, Ronald Laxer11, Tzielan Lee12, Danielle Bullock13, Charles H Spencer14, Jennifer Weiss15, Melissa Hazen16, Edward Oberle17, Melissa Mannion18, Nancy Pan19, Michael Shishov20, Danielle Fair21, Mary Toth22, Kendra Wiegand7 and Esi Morgan23, 1Penn State Children's Hospital, Hershey, PA, 2Children's Mercy Kansas City, Overland Park, KS, 3Atrium Health Levine Children's, Charlotte, NC, 4Medical University of South Carolina, Charleston, SC, 5Texas Children's Hospital/ Baylor College of Medicine, Houston, TX, 6Pediatric Rheumatology Care and Outcomes Improvement Network, Philadelphia, 7Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 8Children's Hospital of Philadelphia, Philadelphia, PA, 9McMaster University, Hamilton, ON, Canada, 10Cohen Children's Medical Center, Lake Success, NY, 11Division of Rheumatology, The Hospital for Sick Children; Child Health Evaluative Services, SickKids Research Institute; Department of Paediatrics, University of Toronto, Toronto, ON, Canada, 12Stanford University School of Medicine, Palo Alto, CA, 13University of Minnesota, Minneapolis, MN, 14Division of Rheumatology, Nationwide Children’s Hospital and Department of Pediatrics, The Ohio State University, Columbus, MS, 15Hackensack University Medical Center, Hackensack, NJ, 16Boston Children's Hospital, Boston, MA, 17Division of Rheumatology, Nationwide Children's Hospital and Department of Pediatrics, The Ohio State University, Columbus, OH, 18University of Alabama at Birmingham, Birmingham, AL, 19Hospital for Special Surgery, New York, NY, 20Phoenix Children's Hospital, Phoenix, AZ, 21Medical College of Wisconsin/Children's Wisconsin, Wauwatosa, WI, 22Nemours Foundation, Orlando, FL, 23Seattle Children's Hospital, Seattle, WA

    Background/Purpose: Pediatric Rheumatology Care and Outcomes Improvement Network (PR-COIN) is a Learning Health Network designed to improve outcomes of care for children with juvenile idiopathic…
  • Abstract Number: 1309 • ACR Convergence 2022

    Evaluation of Preference and Efficacy in the Treatment of Glucocorticoid-induced Osteoporosis in Patients with Autoimmune Diseases Receiving Zoledronic Acid

    Ji-Won Kim1, Ju-Yang Jung1, Hyoun-Ah Kim1 and Chang-Hee Suh2, 1Ajou University School of Medicine, Suwon, Republic of Korea, 2Ajou University Hospital, Suwon, Republic of Korea

    Background/Purpose: The most commonly used drugs for glucocorticoid-induced osteoporosis (GIOP) is bisphosphonates, which include oral alendronate and risedronate, and intravenous zoledronic acid. Among them, zoledronic…
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