ACR Meeting Abstracts

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  • Abstract Number: 0315 • ACR Convergence 2024

    Microvascular Abnormalities Are Present in Autonomic Dysfunction: Results of a Prospective Study

    Sehreen Mumtaz1, Karissa Arca2, Vikas Majithia3, David Hodge3, William Cheshire3 and Florentina Berianu4, 1Mayo Clinic, Florida, Jacksonville, FL, 2Mayo Clinic Arizona, Scottsdale, AZ, 3Mayo Clinic Florida, Jacksonville, FL, 4mayo clinic, Ponte Vedra Beach, FL

    Background/Purpose: Dysfunction of the autonomic system affects multiple target organs and is linked to microvascular impairment and abnormal vasoreactivity. Given its variable manifestations, diagnosis is…
  • Abstract Number: 0446 • ACR Convergence 2024

    Rheum for Improvement: Contraception Counseling and Adherence in Patients with Lupus and Rheumatoid Arthritis on Teratogenic Medications

    Kathryn Kompa1 and Vasileios Kyttaris2, 1Beth Israel Deaconess Medical Center, Boston, MA, 2BIDMC, Boston, MA

    Background/Purpose: Methotrexate (MTX) and mycophenolate (MMF) are two common medications for both lupus (SLE) and rheumatoid arthritis (RA). Both medications are contraindicated in pregnancy, necessitating…
  • Abstract Number: 0396 • ACR Convergence 2024

    Inflammatory Markers of Autoimmune Uveitis in the Eye, Tears and Blood

    Maryrose Hahn1, Madison Mangin2, Kellen Winden3, Pui Lee4, Mindy Lo2, Bharti Nihalani-Gangwani2, Yasmin Massoudi5, Tate Valerio5, Amanda Colombo5, Jessica Scott6, Stephen Anesi6, C. Stephen Foster6, Peter Nigrovic7, sheila Angeles-Han8, Peter Chang6 and Margaret Chang2, 1Boston Children's Hospital, Georgetown, MA, 2Boston Children's Hospital, Boston, MA, 3Boston Children's Hospital, Boston, MA, 4Boston Children's Hospital, Newton, MA, 5Massachusetts Eye Research and Surgery Institution, Waltham, MA, 6Massachusetts Eye Research and Surgery Institution, Waltham, 7Boston Children's Hospital, Brookline, MA, 8Cincinnati Children's Hospital, Cincinnati, OH

    Background/Purpose: Autoimmune uveitis is an inflammatory disorder of the eye that is associated with significant morbidity, including vision-threatening complications and chronic reliance on immunosuppressive therapies.…
  • Abstract Number: 0333 • ACR Convergence 2024

    Predictors of Transplant-Free Survival in Idiopathic Inflammatory Myopathies- associated Interstitial Lung Disease

    shiri keret1, Raisa Silva2, Irada Choudhuri2, Eugenia Gkiaouraki3, Tanya Chandra4, Nantakarn Pongtarakulpanit5, shreya Sriram3, silvia Martinez Laverde3, Dana Ascherman3, Siamak Mogahadam5, Chester Oddis5 and Rohit Aggarwal6, 1Rheumatology unit, Bnai-Zion medical center and the faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel., Atlit, Israel, 2Internal medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, 3Division of Rheumatology and Clinical Immunology, University of Pittsburgh Medical Center, Pittsburgh, PA, 4University of Pittsburgh Medical Center, Pittsburgh, PA, 5Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 6Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, PA

    Background/Purpose: Lung involvement is the most common and severe extra-muscular manifestation of Idiopathic Inflammatory Myopathies (IIM). Early identification of patients at risk for lung transplant…
  • Abstract Number: 0479 • ACR Convergence 2024

    Constructing and Using a Novel Nucleotide Transformer for Patients with Rheumatoid Arthritis

    Shant Ayanian, Collin Osborne, Marc Blasi, Daniel Darveaux, Eric Klee and Elena Myasoedova, Mayo Clinic, Rochester, MN

    Background/Purpose: Applying the methods of artificial intelligence (AI) to genomic data for clinical outcome prediction in rheumatoid arthritis (RA) is an area of growing research.…
  • Abstract Number: 0474 • ACR Convergence 2024

    Association Between Rheumatoid Arthritis and Survival After Cancer: A Systematic Literature Review and Meta-analysis

    Joshua Hsieh1, Avneet Kaur2, Hemant Khandelia3, Teresa Jewell4, Aman Singh5, Lauren Barkley6, Ishan Bansal7, Simmi Oberoi8 and Namrata Singh9, 1Lakeside High School, Seattle, WA, 2SUNY Upstate, Buffalo, NY, 3AIIMS, New Delhi, Delhi, India, 4University of Washington, Seattle, WA, 5Rajindra Hospital, Patiala, Punjab, India, 6Brandeis University, Boston, MA, 7Yale University, New Haven, CT, 8Rajindra Hospital, New Delhi, India, 9University of Washington, Bellevue, WA

    Background/Purpose: Increasing evidence suggests that inflammation, a hallmark of rheumatoid arthritis (RA), is associated with an elevated risk of cancer and can influence cancer outcomes.…
  • Abstract Number: 0432 • ACR Convergence 2024

    Disease Activity During Pregnancy in Patients with Rheumatoid Arthritis or Spondyloarthritis: Results from the Multicentre Prospective GR2 Study

    Marion couderc1, celine lambert2, sabrina hamroun3, denis gallot4, Nathalie Costedoat-chalumeau5, Laure Gossec6, Gaëlle Guettrot-Imbert7, Veronique LE GUERN7, Christophe Richez8, MArtin Soubrier9 and Anna Molto10, 1CHU de Clermont-Ferrand, Clermont-Ferrand, 2chu clermont ferrand, clermont ferrand, France, 3Rheumatology Department - Cochin Hospital, Paris, France, 4Department of Obstetrics, CHU Clermont-ferrand, Clermont-Ferrand, Auvergne, France, 5University Paris Cité, Paris, France, 6Sorbonne Université, Paris, France, 7Cochin Hospital, Paris, France, 8Université de Bordeaux, Bordeaux, France, 9Gabriel-Montpied Hospital, Clermont-ferrand, France, 10Groupe Hospitalier Cochin, AP-HP, Paris, France

    Background/Purpose: Pregnancy may have a beneficial effect on disease activity in rheumatoid arthritis (RA) but the evidence is more conflicting in spondyloarthritis (SpA). The aim…
  • Abstract Number: 0447 • ACR Convergence 2024

    Pregnancy Outcomes in Women Exposed to Guselkumab: Review of Cases Reported to the Manufacturer’s Global Safety Database

    Connie Lin1, Anja Geldhof2, Mauricio Ballina3, Hetal Patel4 and Hewei Li5, 1Janssen R&D US, Horsham, PA, 2Director Postmarketing Commitments, Leiden, Netherlands, 3Actelion Research & Development, Basel, Switzerland, Gewerbestrasse, Basel-Landschaft, Switzerland, 4Pharmaceutical Companies of Johnson & Johnson, Naperville, IL, 5Janssen Pharmaceutical, Hopewell Township, NJ

    Background/Purpose: Data pertaining to the use of biologics in immunologic diseases are limited on their use during pregnancy. Guselkumab (GUS) is a human IgG1λ mAb…
  • Abstract Number: 0459 • ACR Convergence 2024

    Tocilizumab Demonstrates Superior Inhibition of MMP-Mediated Basement Membrane Collagen Degradation Compared to Methotrexate or Placebo

    Dovile Sinkeviciute1, Sofie Falkenloeve Madsen2, Nicolas Willumsen3, Patryk Drobinski3, Morten Karsdal3 and Anne-Christine Bay-Jensen3, 1Nordic Bioscience, Herlev, Hovedstaden, Denmark, 2University of Copenhagen, Copenhagen N, Denmark, 3Nordic Bioscience, Herlev, Denmark

    Background/Purpose: Rheumatoid arthritis (RA) pathogenesis involves a range of immune cells, for instance T-cells, neutrophils and macrophages. They produce proinflammatory factors, such as proteolytic enzymes,…
  • Abstract Number: 0440 • ACR Convergence 2024

    Pregnancy Outcome Disparities Among Women with Systemic Lupus Erythematosus

    Jessica English1, Bethany Wolf2 and Diane Kamen2, 1Medical University of South Carolina, Johns Island, SC, 2Medical University of South Carolina, Charleston, SC

    Background/Purpose: Women with systemic lupus erythematosus (SLE) have increased rates of pre-term birth, small for gestational age babies, and pre-eclampsia compared to women without a…
  • Abstract Number: 0485 • ACR Convergence 2024

    Biomarkers for Disease Activity and Response to Treatment in Early Rheumatoid Arthritis: Metabolomics and Machine Learning Analyses in NORD-STAR Cohort

    Tahzeeb Fatima1, Yuan Zhang2, Georgios Vasileiadis2, Araz Rawshani2, Ronald Van Vollenhoven3, Jon Lampa4, Bjorn Gudbjornsson5, Espen Haavardsholm6, Dan Nordstrom7, Gerdur Gröndal5, Kim Hørslev-Petersen8, Kristina Lend9, Marte Heiberg10, Merete Hetland11, Michael Nurmohamed12, Mikkel Ostergaard13, Tillmann Uhlig6, Tuulikki Sokka-Isler14, Anna Rudin15 and Cristina Maglio2, 1University of Gothenburg, Göteborg, Sweden, 2University of Gothenburg, Gothenburg, Sweden, 3Department of Rheumatology and Clinical Immunology, Amsterdam University Medical Centers, Amsterdam, Netherlands, 4Karolinska University Hospital, Hässelby, Sweden, 5Landspitali University Hospital and University of Iceland, Reykjavik, Iceland, 6Diakonhjemmet Hospital, Oslo, Norway, 7Helsinki University Hospital, Helsinki, Finland, 8University Hospital of Southern Denmark, Sønderborg, Denmark, 9Amsterdam UMC, Karolinska Institute, Stockholm, Sweden, 10Diakonhjemmet Hospital, Oslo, Oslo, Norway, 11Rigshospitalet Glostrup and University of Copenhagen, Glostrup, Denmark, 12Amsterdam University Medical Centers, Amsterdam, Netherlands, 13Department of Clinical Medicine, University of Copenhagen and Center for Rheumatology, Copenhagen Center for Arthritis Research, Glostrup, Denmark, 14Jyväskylä Central Hospital, Jyväskylä, Finland, 15Institute of Medicine, University of Gothenburg, Gothenburg, Sweden

    Background/Purpose: The variability in treatment response in people with rheumatoid arthritis (RA) warrants the prediction of patients at high risk of treatment failure. Identification of…
  • Abstract Number: 0463 • ACR Convergence 2024

    Evaluation of Inflammatory Indices as Predictive Biomarkers of Carotid Plaque in Patients with Rheumatoid Arthritis

    Jose Antonio Davila Jimenez1, Dionicio Galarza-Delgado2, Iris Jazmín Colunga Pedraza3, jose Ramon Azpiri-Lopez4, Rosa Icela Arvizu-Rivera3, Jesus Cardenas-de la Garza5, Aleydis Gonzalez Melendez3, Andrea Guajardo Aldaco3, Maria F. Elizondo-Benitez6, Rebeca L. Polina-Lugo3 and Diego Salcedo-Almanza7, 1Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo León, Mexico, 2UANL Hospital Universitario, Monterrey, Nuevo León, Mexico, 3Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Mexico, 4Division of Cardiology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Mexico, 5Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico, 6Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo León, Mexico, 7Division of Radiology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo León, Mexico

    Background/Purpose: Patients with rheumatoid arthritis (RA) have an increased cardiovascular (CV) risk compared to the general population. All stages of the atherogenic process appear to…
  • Abstract Number: 0469 • ACR Convergence 2024

    SCORE2 Is Superior to SCORE in Predicting the Presence of Carotid Plaques and Intima-media Thickness in Rheumatoid Arthritis Patients: A Cross-sectional Study with Carotid Ultrasound

    Cristina Campos Fernández1, Jorge Juan Fragío Gil2, Roxana González Mazario3, Pablo Martínez Calabuig4, Laura Salvador Maicas5, Mireia Lucía Sanmartín Martínez6, Iván Jesús Lorente Betanzos6, Clara Molina Almela6, juan José Lerma Garrido7, Amalia Rueda3 and Jose A Román-Ivorra8, 1Escuela de Doctorado, Universidad Católica de Valencia San Vicente Mártir, Valencia, Spain, 2Hospital General Universitario, Valencia, Comunidad Valenciana, Spain, 3Hospital General de Valencia, Valencia, Comunidad Valenciana, Spain, 4HOSPITAL GENERAL UNIVERSITARIO VALENCIA SPAIN, Ontinyent, Comunidad Valenciana, Spain, 5Consorcio Hospital General Universitario de Valencia, Castellón de la Plana, Comunidad Valenciana, Spain, 6Consorcio Hospital General Universitario de Valencia, Valencia, Comunidad Valenciana, Spain, 7Hospital General Universitario Valencia, Valencia, Comunidad Valenciana, Spain, 8Hospital Universitari i Politècnic la Fe, Valencia, Comunidad Valenciana, Spain

    Background/Purpose: Rheumatoid arthritis (RA) escalates the risk of premature mortality, predominantly through cardiovascular diseases. Although SCORE and its updated version, SCORE2, are employed to assess…
  • Abstract Number: 0428 • ACR Convergence 2024

    Placental Characteristics in Systemic Lupus Erythematosus Pregnancies Resulting in Small for Gestational Age Infants

    Rashmi Dhital1, Marni Jacobs2, Chelsey Smith3 and Mana Parast2, 1UC San Diego, Brentwood, TN, 2UC San Diego, San Diego, CA, 3UC San Diego, LA JOLLA, CA

    Background/Purpose: About a quarter of pregnant individuals with systemic lupus erythematosus (SLE) have small for gestational age (SGA) infants. We aim to characterize placental pathology…
  • Abstract Number: 0473 • ACR Convergence 2024

    Immune Checkpoint–Induced Arthritis: A Comprehensive Single Cohort Descriptive Analysis from Clinical Evaluation to Histology

    NATALUCCI Francesco1, SOKOLOVA Tatiana2, NZEUSSEU TOUKAP Adrien3, GALANT Christine4, ABOUBAKAR Frank5, BAURAIN Jean-François6, CORNELIS Frank6, BORBATH Yvan7, DUREZ Patrick2 and MERIC de BELLEFON Laurent2, 1Sapienza University of Roma, Rheumatology, Department of Clinical, Internistic, Anesthesiological and cardiovascular sciences, Roma, Italy, 2Cliniques Universitaires Saint-Luc – Université catholique de Louvain (UCLouvain) – Institut de Recherche Expérimentale et Clinique (IREC), Rheumatology, Brussels, Belgium, 3Institut de Recherche Expérimentale et Clinique, Cliniques universitaires Saint-Luc, Université catholique de Louvain, St.-Lambrechts-Woluwe, Belgium, 4Department of Pathological Anatomy, Cliniques Universitaires Saint-Luc, Brussels, Belgium, 5Division of Pneumology, Cliniques Universitaires Saint-Luc, Brussels, Brussels, Belgium, 6Medical Oncology Department, Université Catholique de Louvain and Cliniques Universitaires Saint-Luc, Brussels, Belgium, 7Department of Hepato-gastroenterology, Cliniques Universitaires St Luc, Brussels, Belgium

    Background/Purpose: The increasing use of Immune Check-Point Inhibitors (ICIs) to treat malignancy focused attention on immune-related adverse events (irAEs). ICIs-induced arthritis is the most common…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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