ACR Meeting Abstracts

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  • Abstract Number: 0265 • ACR Convergence 2025

    Influence of Menopausal Status on Coronary Artery Calcium Burden and Cardiovascular Computed Tomography Abnormalities in Inflammatory Arthritis

    Mohammed Mohammed1, Bindee Kuriya2, Lihi Eder1, Elsie Nguyen3, Shadi Ahktari4, Paula Harvey5, Wei Wu6 and Sohan Shahab7, 1University of Toronto, Toronto, ON, Canada, 2University of Toronto - Toronto, Toronto, ON, Canada, 3University of Toronto, Toronto, 4University of Toronto Department of Medicine and Women's College Hospital, Toronto, Canada, 5University of Toronto Department of Medicine and Women's College Hospital, Toronto, ON, Canada, 6University of Toronto, Toronto, Canada, 7Women’s College Research Institute, Women’s College Hospital, Toronto, Canada

    Background/Purpose: Patients with inflammatory arthritis (IA) have increased cardiovascular risk. Coronary artery calcium (CAC) scoring by computed tomography (CT) detects early coronary disease and structural…
  • Abstract Number: 0346 • ACR Convergence 2025

    Fibroblast Growth Factor-23 and Bone Status in Patients with Chronic Kidney Disease Compared to a Healthy Control Group and Its Relationship with Cardiovascular Risk

    José Rodríguez gago1, Carolina Tornero2, Lina León3, María Luisa González-Casaus3, Luisa Fernanda Giraldo3, Gloria del Peso3, Diego Garrido3, Teresa López3, Mónica Coronado3, María Auxiliadora Bajo4, Sara García3, María Gema Serrano3, Marta Ossorio3, Alejandro Balsa3 and Pilar Aguado3, 1Hospital Universitario La Paz, MADRID, 2Hospital La Paz, Madrid, Spain, 3Hospital Universitario La Paz, Madrid, Spain, 4Hospital Universitario de la Princesa - ISS Princesa, Madrid, Spain

    Background/Purpose: Chronic kidney disease (CKD) is linked to increased vascular comorbidity and fracture risk. This study aims to assess bone status in CKD patients versus…
  • Abstract Number: 0367 • ACR Convergence 2025

    Differences in Self-Reported Medication Nonadherence and its Drivers in Young Adults versus Older Adults with Systemic Lupus Erythematosus

    Hannah Concannon1, Kai Sun2, Jennifer Rogers3, Megan Clowse4, Rachel Randell2, Mithu Maheswaranathan5, Lisa Criscione-Schreiber5, Nathaniel Harris6, Amanda Eudy7 and Rebecca Sadun2, 1Duke University School of Medicine, Chapel Hill, NC, 2Duke University, Durham, NC, 3Duke, Durham, NC, 4Duke University, Chapel Hill, NC, 5Duke University School of Medicine, Durham, NC, 6Duke University Medical Center, Durham, NC, 7Duke University, Raleigh, NC

    Background/Purpose: Medication adherence poses a challenge for patients with SLE, especially younger patients, who often experience both more active disease and more intensive treatments than…
  • Abstract Number: 0309 • ACR Convergence 2025

    A Composite Cumulative Cartilage Damage Metric Predicts Incident Symptomatic Knee OA: Data from the Osteoarthritis Initiative

    Julieann Patarini1, Timothy McAlindon2, Jonggyu Baek1, Emily Kirillov3, Nhung Vo3, Michael Richard3, Ming Zhang4, Matthew Harkey5, Grace Lo6, Shao-Hsien Liu1, Kate Lapane1, Charles Eaton7, James Mackay8 and Jeffrey Driban9, 1UMass Chan Medical School, Worcester, MA, 2UMass Chan School of Medicine, Arlington, MA, 3Tufts Medical Center, Boston, MA, 4Boston University, Westford, MA, 5Michigan State University, East Lansing, MI, 6Baylor College of Medicine / MEDVAMC, Houston, TX, 7Brown University, Pawtucket, RI, 8University of Cambridge; Norwich Medical School, San Diego, CA, 9University of Massachusetts Chan Medical School, Marlborough, NH

    Background/Purpose: Cartilage defects are a hallmark of OA progression. We previously developed a composite MRI-based metric that combines cartilage damage from 6 anatomical regions throughout…
  • Abstract Number: 0334 • ACR Convergence 2025

    Diagnostic Test Accuracy of Ultrasound for Detecting Knee Osteoarthritis: A Systematic Review and Meta-Analysis

    Mohamed Abdelsalam1, Hadeer Hafez2, Maryam Lasheen3, Bassant Elaraby Elsayed Badwy4, Omar Sameh Nabil El Sedafy1, Menat Alla Ayman Ali Mahdy4, Hazem E. Mohammed5 and Mohamed Reda Awad6, 1Misr University For Science and Technology, 6 october, Al Jizah, Egypt, 26th October University, 6 october, Al Jizah, Egypt, 3Misr University For Science and Technology, Helwan, Al Qahirah, Egypt, 4Misr University For Science and Technology, Nasr City, Al Qahirah, Egypt, 5Faculty of Medicine, Assiut university, Assiut, Egypt, assyut, Asyut, Egypt, 6Al Azhar University, Cairo, Egypt, Giza, Al Jizah, Egypt

    Background/Purpose: Ultrasound (US) is an emerging, promising imaging modality offering a safe, radiation-free, and cost-effective option for diagnosing and assessing structural changes in knee osteoarthritis…
  • Abstract Number: 0329 • ACR Convergence 2025

    Machine Learning-Based Model to Predict Rapid Structural Progression in Knee Osteoarthritis

    Maria Fernanda Gonzalez Hernandez1, Ignacio rego Pérez2, Isabel Rodríguez Valle3, Jorge Vázquez García4, Vanesa Balboa5, Sara Relaño Fernández4, María C. de Andrés6, Lucía Lourido7, Valentina Calamia7, Rocio Paz González4, Patricia Quaranta7, Patricia Fernández-Puente4, Nicola Veronese8, Cristina Ruiz-Romero9, Natividad Oreiro10 and francisco J Blanco11, 1Instituto de Investigacion Biomedica de A Coruna (INIBIC), A coruña, Galicia, Spain, 2Department of Rheumatology, Rheumatology Research Group (GIR) Biomedical Re-search Institute (INIBIC), A Coruña, Spain, 3Instituto de Investigacion Biomedica de A Coruna (INIBIC), Coruña, Galicia, Spain, 4Instituto de Investigacion Biomedica de A Coruna (INIBIC), coruña, Spain, 5Grupo de Investigación de Reumatología (GIR). Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, coruña, Spain, 6Instituto de Investigación Biomédica de A Coruña (INIBIC), Grupo de Investigación de Reumatología (GIR), A Coruña, Spain, 7Instituto de Investigacion Biomedica de A Coruna (INIBIC), coruna, Spain, 8Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, palermo, Italy, 9Department of Rheumatology, Rheumatology Research Group (GIR) Biomedical Re-search Institute (INIBIC),, A Coruña, Spain, 10CHUAC, La Coruna, Spain, 11INIBIC-University of A Coruña, A Coruña, Galicia, Spain

    Background/Purpose: Osteoarthritis (OA) is the most common chronic joint disorder, characterized by structural cartilage and bone damage that often causes pain and disability. However, the…
  • Abstract Number: 0314 • ACR Convergence 2025

    What changes in quality of life can be observed in patients with knee or hip OA prior to total hip or total knee replacement surgery ? data from the KHOALA cohort

    Anne-Christine Rat1, LATOURTE Augustin2, Maud Wieczorek3, Jérémie sellam4, willy Ngueyon Sime5, Jacques Pouchot6, Christian Roux7, Alain SARAUX8, Francis Guillemin9 and Joel Coste10, 1Caen University hospital, UMR 1075 Caen normandy university, Caen, France, 2Rheumatology Department, Lariboisiere Hospital, Paris, France, 3Lausanne Univserty, Lausanne, Switzerland, 4Saint-Antoine hospital, Assistance Publique – Hôpitaux de Paris, Paris, France, Sorbonne University, Paris, France, 5CIC, Epidémiologie Clinique, CHRU-Nancy, Inserm, Université de Lorraine, Nancy, France, nNancy, France, 6HEGP hospital, Assistance Publique-Hopitaux de Paris,, Paris, France, 7CHU Nice, Nice, France, 8CHU Brest, Brest, France, 9CHU Nancy, Nancy, France, 10, Assistance Publique – Hôpitaux de Paris, Paris, France

    Background/Purpose: Few studies have examined how the quality of life (QoL) evolves in patients with osteoarthritis (OA) before undergoing total hip or total knee replacement…
  • Abstract Number: 0283 • ACR Convergence 2025

    The Performance of Rule-Based Algorithms to Identify Patients With Idiopathic Inflammatory Myopathies in Electronic Health Records

    Ana Valle1, Amy Vo2, Rochelle Castillo1, Yumeko Kawano3, Leah Santacroce3, Daniel Solomon4, Katherine Liao3 and Candace Feldman3, 1Brigham and Women's Hospital, Brookline, MA, 2Harvard Medical School, Boston, 3Brigham and Women's Hospital, Boston, MA, 4Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Idiopathic inflammatory myopathies (IIM; including dermatomyositis, polymyositis, and inclusion body myositis) are heterogenous systemic inflammatory conditions that cause significant disability and morbidity. The study…
  • Abstract Number: 0303 • ACR Convergence 2025

    A Predictive Model for Liver Enzyme Elevations Based on Creatine Kinase in Idiopathic Inflammatory Myopathies

    Shiri Keret1, Tanya Chandra2, Nantakarn Pongtarakulpanit2, Kaushik Sreerama Reddy2, Jesse Wilkerson3, Siamak Moghadam-Kia4, Dana Ascherman5, Chester V. Oddis5 and Rohit Aggarwal6, 1Bnai Zion Medical Center, Atlit, Israel, 2University of Pittsburgh Medical Center, Pittsburgh, 3DLH, Bethesda, MD, 4University of Pittsburgh Medical Center, Pittsburgh, PA, 5University of Pittsburgh, Pittsburgh, PA, 6University of Pittsburgh, Rheumatology and Clinical Immunology, Pittsburgh, United States of America, Pittsburgh, PA

    Background/Purpose: Idiopathic inflammatory myopathies (IIM) are characterized by elevated muscle enzymes, including creatine kinase (CK), aldolase, aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase…
  • Abstract Number: 0246 • ACR Convergence 2025

    Fracture Risk in Intestinal Autoimmune-mediated Diseases Patients: Clinical Insights from REMS

    Marco Di Paola1, Fiorella Anna Lombardi1, Edmund J MacLaughlin2, Maurizio Muratore3, Kathleen Methric4, Gianmarco Del Vecchio5, Giusy Peluso6, Chiara Stomaci7, Roberto Franchini1, Francesco Conversano1, Paola Pisani1 and Sergio Casciaro1, 1Institute of Clinical Physiology, National Research Council, Lecce, Puglia, Italy, 2Rheumatology Associates of Delmarva and BoneVue Diagnostics, Easton, MD, 3ASL- LE, "Vito Fazzi" Hospital, Lecce, Puglia, Italy, 4BoneVue Diagnostics, Catonsville, MD, 5Department of Research and Development, Echolight S.p.a., Lecce, Puglia, Italy, 6Department of Innovative Engineering, University of Salento, Lecce, Puglia, Italy, 7Department of Biological and Envinronmental Sciences and Technologies, University of Salento, Lecce, Puglia, Italy

    Background/Purpose: Intestinal Bowel Diseases (IBD), including Crohn’s (ChD), and Ulcerative Colitis (UCD), along with Celiac (ClD), diseases are chronic inflammatory conditions that primarily affect the…
  • Abstract Number: 0332 • ACR Convergence 2025

    Safety, Short- and Long-Term Efficacy of Methotrexate in Osteoarthritis: A Systematic Review and Meta-Analysis

    Mohamed Abdelsalam1, Maryam Lasheen2, Hadeer Hafez3, Bassant Elaraby Elsayed Badwy4, Omar Sameh Nabil El Sedafy1 and Mohamed Reda Awad5, 1Misr University For Science and Technology, 6 october, Al Jizah, Egypt, 2Misr University For Science and Technology, Helwan, Al Qahirah, Egypt, 36th October University, 6 october, Al Jizah, Egypt, 4Misr University For Science and Technology, Nasr City, Al Qahirah, Egypt, 5Al Azhar University, Cairo, Egypt, Giza, Al Jizah, Egypt

    Background/Purpose: Methotrexate (MTX), traditionally used for inflammatory conditions like rheumatoid arthritis, has well-established anti-inflammatory properties, recently gained interest as a potential therapeutic option for osteoarthritis…
  • Abstract Number: 0230 • ACR Convergence 2025

    An Epic journey – Therapeutic Drug Monitoring at an Academic Center

    Puja Khanna1 and Michael Rice2, 1Division of Rheumatology, University of Michigan, Ann Arbor, MI, 2Division of Gastroenterology, University of Michigan, Ann Arbor, MI

    Background/Purpose: Non-oncologic use of immunomodulatory agents is increasing. These drugs have a narrow, patient-specific therapeutic index, making therapeutic drug monitoring essential for safe prescribing. However,…
  • Abstract Number: 0323 • ACR Convergence 2025

    Automated Effusion-Synovitis Volume is Prognostic and Responsive to Knee Osteoarthritis Progression: Data from the Osteoarthritis Initiative

    Jeffrey Driban1, Kate Lapane2, Shao-Hsien Liu2, Jonggyu Baek2, Grace Lo3, Matthew Harkey4, Charles Eaton5, James Mackay6, Timothy McAlindon7, Mohammad Chowdhury8, Zhen Cao9, Juan Shan10 and Ming Zhang11, 1University of Massachusetts Chan Medical School, Marlborough, NH, 2UMass Chan Medical School, Worcester, MA, 3Baylor College of Medicine / MEDVAMC, Houston, TX, 4Michigan State University, East Lansing, MI, 5Brown University, Pawtucket, RI, 6University of Cambridge; Norwich Medical School, San Diego, CA, 7UMass Chan School of Medicine, Arlington, MA, 8Pace University, New York City, NY, 9Boston University, Boston, MA, 10Pace University, New York, NY, 11Boston University, Westford, MA

    Background/Purpose: Semi-quantitative and semi-automated quantitative measurements of effusion-synovitis (ES) are prognostic for knee OA progression. Changes in these metrics relate to changes in knee pain.…
  • Abstract Number: 0328 • ACR Convergence 2025

    High synovial fluid leukocyte counts and markers of TLR activation correlate with poorer response to injections in patients with knee OA

    Lance Murphy1, Baofeng Hu2, Vu Nguyen3, Bryant England4, Katherine Wysham5, Mercedes Quinones6, Joshua Baker3 and Carla Scanzello3, 1University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 2University of Pennsylvania, Wynnewood, PA, 3University of Pennsylvania, Philadelphia, PA, 4University of Nebraska Medical Center, Omaha, NE, 5VA PUGET SOUND/UNIVERSITY OF WASHINGTON, Seattle, WA, 6Washington DC VA Medical Center, Bethesda, MD

    Background/Purpose: Toll-like receptors (TLRs) are pattern-recognition receptors of the innate immune response and are important in driving the initial activation of myeloid lineage cells to…
  • Abstract Number: 0333 • ACR Convergence 2025

    Diagnostic Test Accuracy of Artificial Intelligence in Early Diagnosis of Osteoarthritis: A Systematic Review and Meta-Analysis of 45,588 Knees

    Mohamed Abdelsalam1, Hadeer Hafez2, Omar Sameh Nabil El Sedafy1, Nourhan Abouelella3, Ahmed Abdulhafeez Hamza3, Omnia Samy El-Sayed4, Mohamed Reda Awad5, Gihan Omar3 and Hazem E. Mohammed6, 1Misr University For Science and Technology, 6 october, Al Jizah, Egypt, 26th October University, 6 october, Al Jizah, Egypt, 3Faculty of Medicine, Misr University for Science and Technology, 6 october, Al Jizah, Egypt, 4Misr University For Science and Technology, Nasr City, Al Qahirah, Egypt, 5Al Azhar University, Cairo, Egypt, Giza, Al Jizah, Egypt, 6Faculty of Medicine, Assiut university, Assiut, Egypt, assyut, Asyut, Egypt

    Background/Purpose: Artificial intelligence (AI) rapid advancement opens new opportunities in the field of rheumatology. With better imaging, AI may help find early osteoarthritic changes that…
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