ACR Meeting Abstracts

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  • Abstract Number: 0333 • ACR Convergence 2025

    Diagnostic Test Accuracy of Artificial Intelligence in Early Diagnosis of Osteoarthritis: A Systematic Review and Meta-Analysis of 45,588 Knees

    Mohamed Abdelsalam1, Hadeer Hafez2, Omar Sameh Nabil El Sedafy1, Nourhan Abouelella3, Ahmed Abdulhafeez Hamza3, Omnia Samy El-Sayed4, Mohamed Reda Awad5, Gihan Omar3 and Hazem E. Mohammed6, 1Misr University For Science and Technology, 6 october, Al Jizah, Egypt, 26th October University, 6 october, Al Jizah, Egypt, 3Faculty of Medicine, Misr University for Science and Technology, 6 october, Al Jizah, Egypt, 4Misr University For Science and Technology, Nasr City, Al Qahirah, Egypt, 5Al Azhar University, Cairo, Egypt, Giza, Al Jizah, Egypt, 6Faculty of Medicine, Assiut university, Assiut, Egypt, assyut, Asyut, Egypt

    Background/Purpose: Artificial intelligence (AI) rapid advancement opens new opportunities in the field of rheumatology. With better imaging, AI may help find early osteoarthritic changes that…
  • Abstract Number: 0329 • ACR Convergence 2025

    Machine Learning-Based Model to Predict Rapid Structural Progression in Knee Osteoarthritis

    Maria Fernanda Gonzalez Hernandez1, Ignacio rego Pérez2, Isabel Rodríguez Valle3, Jorge Vázquez García4, Vanesa Balboa5, Sara Relaño Fernández4, María C. de Andrés6, Lucía Lourido7, Valentina Calamia7, Rocio Paz González4, Patricia Quaranta7, Patricia Fernández-Puente4, Nicola Veronese8, Cristina Ruiz-Romero9, Natividad Oreiro10 and francisco J Blanco11, 1Instituto de Investigacion Biomedica de A Coruna (INIBIC), A coruña, Galicia, Spain, 2Department of Rheumatology, Rheumatology Research Group (GIR) Biomedical Re-search Institute (INIBIC), A Coruña, Spain, 3Instituto de Investigacion Biomedica de A Coruna (INIBIC), Coruña, Galicia, Spain, 4Instituto de Investigacion Biomedica de A Coruna (INIBIC), coruña, Spain, 5Grupo de Investigación de Reumatología (GIR). Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas, coruña, Spain, 6Instituto de Investigación Biomédica de A Coruña (INIBIC), Grupo de Investigación de Reumatología (GIR), A Coruña, Spain, 7Instituto de Investigacion Biomedica de A Coruna (INIBIC), coruna, Spain, 8Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, palermo, Italy, 9Department of Rheumatology, Rheumatology Research Group (GIR) Biomedical Re-search Institute (INIBIC),, A Coruña, Spain, 10CHUAC, La Coruna, Spain, 11INIBIC-University of A Coruña, A Coruña, Galicia, Spain

    Background/Purpose: Osteoarthritis (OA) is the most common chronic joint disorder, characterized by structural cartilage and bone damage that often causes pain and disability. However, the…
  • Abstract Number: 0334 • ACR Convergence 2025

    Diagnostic Test Accuracy of Ultrasound for Detecting Knee Osteoarthritis: A Systematic Review and Meta-Analysis

    Mohamed Abdelsalam1, Hadeer Hafez2, Maryam Lasheen3, Bassant Elaraby Elsayed Badwy4, Omar Sameh Nabil El Sedafy1, Menat Alla Ayman Ali Mahdy4, Hazem E. Mohammed5 and Mohamed Reda Awad6, 1Misr University For Science and Technology, 6 october, Al Jizah, Egypt, 26th October University, 6 october, Al Jizah, Egypt, 3Misr University For Science and Technology, Helwan, Al Qahirah, Egypt, 4Misr University For Science and Technology, Nasr City, Al Qahirah, Egypt, 5Faculty of Medicine, Assiut university, Assiut, Egypt, assyut, Asyut, Egypt, 6Al Azhar University, Cairo, Egypt, Giza, Al Jizah, Egypt

    Background/Purpose: Ultrasound (US) is an emerging, promising imaging modality offering a safe, radiation-free, and cost-effective option for diagnosing and assessing structural changes in knee osteoarthritis…
  • Abstract Number: 0295 • ACR Convergence 2025

    Multidimensional Analysis of Fatigue in Idiopathic Inflammatory Myopathies: Clinical, Psychological, and Sociodemographic Determinants

    Manali Sarkar1, Meera Shah2, Vincenzo Venerito3, Vikas Agarwal4 and Latika Gupta5, 1Sir H. N. Reliance Foundation Hospital and Research Centre, Mumbai, Maharashtra, India., Mumbai, Maharashtra, India, 2Indraprastha Apollo Hospital, New Delhi, Mumbai, Maharashtra, India, 3Univeristy of Bari "Aldo Moro", Italy, Bari, Bari, Italy, 4Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India, 5School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham; Royal Wolverhampton NHS Trust; Centre for Musculoskeletal Research, School of Biological Sciences, The University of Manchester, Manchester; Francis Crick Institute, London, Birmingham, UK, United Kingdom

    Background/Purpose: Fatigue significantly impacts quality of life in idiopathic inflammatory myopathies (IIM) but remains poorly understood. This study aimed to identify the key determinants of…
  • Abstract Number: 0246 • ACR Convergence 2025

    Fracture Risk in Intestinal Autoimmune-mediated Diseases Patients: Clinical Insights from REMS

    Marco Di Paola1, Fiorella Anna Lombardi1, Edmund J MacLaughlin2, Maurizio Muratore3, Kathleen Methric4, Gianmarco Del Vecchio5, Giusy Peluso6, Chiara Stomaci7, Roberto Franchini1, Francesco Conversano1, Paola Pisani1 and Sergio Casciaro1, 1Institute of Clinical Physiology, National Research Council, Lecce, Puglia, Italy, 2Rheumatology Associates of Delmarva and BoneVue Diagnostics, Easton, MD, 3ASL- LE, "Vito Fazzi" Hospital, Lecce, Puglia, Italy, 4BoneVue Diagnostics, Catonsville, MD, 5Department of Research and Development, Echolight S.p.a., Lecce, Puglia, Italy, 6Department of Innovative Engineering, University of Salento, Lecce, Puglia, Italy, 7Department of Biological and Envinronmental Sciences and Technologies, University of Salento, Lecce, Puglia, Italy

    Background/Purpose: Intestinal Bowel Diseases (IBD), including Crohn’s (ChD), and Ulcerative Colitis (UCD), along with Celiac (ClD), diseases are chronic inflammatory conditions that primarily affect the…
  • Abstract Number: 0303 • ACR Convergence 2025

    A Predictive Model for Liver Enzyme Elevations Based on Creatine Kinase in Idiopathic Inflammatory Myopathies

    Shiri Keret1, Tanya Chandra2, Nantakarn Pongtarakulpanit2, Kaushik Sreerama Reddy2, Jesse Wilkerson3, Siamak Moghadam-Kia4, Dana Ascherman5, Chester V. Oddis5 and Rohit Aggarwal6, 1Bnai Zion Medical Center, Atlit, Israel, 2University of Pittsburgh Medical Center, Pittsburgh, 3DLH, Bethesda, MD, 4University of Pittsburgh Medical Center, Pittsburgh, PA, 5University of Pittsburgh, Pittsburgh, PA, 6University of Pittsburgh, Rheumatology and Clinical Immunology, Pittsburgh, United States of America, Pittsburgh, PA

    Background/Purpose: Idiopathic inflammatory myopathies (IIM) are characterized by elevated muscle enzymes, including creatine kinase (CK), aldolase, aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase…
  • Abstract Number: 0194 • ACR Convergence 2025

    Evaluation of a Home-based Therapeutics Service: Feasibility, Patient and Caregiver Experience, and Cost

    Xiaohui Xin, Andrea Low, Sow Ling Yee, Miao Miao Liu, Christina Tan, Daphne Ng and Siaw Ing Yeo, Singapore General Hospital, Singapore, Singapore

    Background/Purpose: The home-based therapeutics service (HTS) by a community nurse is part of an ongoing larger initiative—Community Therapeutics Programme (CTP)—spearheaded by the Rheumatology and Immunology…
  • Abstract Number: 0232 • ACR Convergence 2025

    Hydroxychloroquine Blood Testing in Lupus: The Michigan Medicine Experience

    Zeinab Saleh1, Michelle Kahlenberg2, Wendy Marder1 and Emily Somers1, 1University of Michigan, Ann Arbor, MI, 2Michigan Medicine, Ann Arbor, MI

    Background/Purpose: Measuring hydroxychloroquine (HCQ) blood levels in patients with systemic lupus erythematosus (SLE) can assess medication adherence and determine whether concentrations fall within the therapeutic…
  • Abstract Number: 0250 • ACR Convergence 2025

    Autoinflammatory diseases in adult patients. Spanish registry.

    Eztizen Labrador-Sanchez1, Diana Prieto-Peña2, Carlota L Iñiguez3, Rafael B. Melero-González4, Alberto Ruiz-Roman5, Clara Moriano6, Paula García-Escudero7, Anahy Maria Brandy8, Marta López9, Fred Anton Pages10, Maria Camila Osorio-SanJuan11, Nahia Plaza-Aulestia12, Bryan Josué Flores Robles13, Estibaliz Andres Trashaedo14 and Ricardo Blanco15, 1Hospital Universitario San Pedro, Laguardia, Spain, 2Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain., Santander, Spain, 3Hospital del Bierzo, Ponferrada, Castilla y Leon, Spain, 4COMPLEXO HOSPITALARIO UNIVERSITARIO DE OURENSE, O Carballino, Spain, 5Hospital Juan Ramon Jimenez, Huelva, Spain, 6Hospital León, LEON, Castilla y Leon, Spain, 7Hospital Universitario Álava, Bilbao, Spain, 8Hospital Germans Trias i Pujol, Badalona, Spain, 9Complex Hospitalari Universitari Moisés Broggi, Barcelona, Spain, 10Hospital General de Segovia, Segovia, Spain, 11Hospital Clínico Lozano Blesa, Zaragoza, Spain, 12Rheumatology division. Galdakao-Usansolo University Hospital, Galdakao, Spain, 13Hospital San Pedro, Logroño, Spain, 14Hospital San Pedro, Logroño, Spain, 15Rheumatology Division, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain, Santander, Cantabria, Spain

    Background/Purpose: Autoinflammatory diseases(AIDs) are characterized by recurrent inflammatory episodes resulting from alterations in regulatory genes, activating the innate immune system. Although these diseases primarily occur…
  • Abstract Number: 0282 • ACR Convergence 2025

    Clinical Meaningfulness and Improvement Thresholds of Myositis Core Set Measures: Association with Patient-Reported Outcomes

    Shiri Keret1, Raisa Lomanto Silva2, Irada Choudhuri3, Eugenia Gkiaouraki3, Tanya Chandra3, Nantakarn Pongtarakulpanit3, Shreya Sriram3, Niladri Bhowmick3, Vaidehi Kothari3, Kaushik Sreerama Reddy3, Eaman Alhassan4, Anushka Aggarwal5, Maha Almackenzie6, Siamak Moghadam-Kia4, Dana Ascherman7, Chester V. Oddis7 and Rohit Aggarwal8, 1Bnai Zion Medical Center, Atlit, Israel, 2Massachusetts General Hospital, Boston, MA, 3University of Pittsburgh Medical Center, Pittsburgh, 4University of Pittsburgh Medical Center, Pittsburgh, PA, 5Indraprastha Apollo Hospital, New Delhi, India, 6Medical Cities of the Ministry of the Interior, Riyadh, Saudi Arabia, 7University of Pittsburgh, Pittsburgh, PA, 8University of Pittsburgh, Rheumatology and Clinical Immunology, Pittsburgh, United States of America, Pittsburgh, PA

    Background/Purpose: The six myositis core set measures (CSMs) are widely utilized to assess disease activity in idiopathic inflammatory myopathies (IIM). However, their association with how…
  • Abstract Number: 0255 • ACR Convergence 2025

    Clearing the Smoke: Association Between Cannabis Use and Autoimmune Disease Incidence in a Retrospective Cohort Analysis

    Justin Riley Lam1, Emmanuel Otabor2, Laith Alomari2, Esteban Kosak Lopez2, Maxim Barnett2 and Shahrzad Abdollahi3, 1Albert Einstein Medical Center, Philadelphia, PA, 2Jefferson Einstein Hospital Philadelphia, Philadelphia, PA, 3Jefferson Einstein Hospital, Philadelphia, PA

    Background/Purpose: Cannabis use has increased substantially in the past decades, with legalization expanding across the U.S. Despite its known therapeutic potential, the immunomodulatory effects of…
  • Abstract Number: 0297 • ACR Convergence 2025

    Longitudinal Serum Proteomic Profiles – A Step Closer to Personalized Monitoring in Dermatomyositis

    Natasha Le Blanc1, Marie Hudson1, Ana Cristina Gonzalez Sanchez2, Lina Marcela Diaz Gallo2 and Valerie Leclair3, 1McGill University, Montréal, QC, Canada, 2Karolinska Institutet, Stockholm, Sweden, 3McGill University, Montréal, Canada

    Background/Purpose: Dermatomyositis (DM) is a multisystemic immune mediated disease presenting with heterogeneous clinical features. Disease monitoring in DM relies in part on biomarkers of muscle…
  • Abstract Number: 0314 • ACR Convergence 2025

    What changes in quality of life can be observed in patients with knee or hip OA prior to total hip or total knee replacement surgery ? data from the KHOALA cohort

    Anne-Christine Rat1, LATOURTE Augustin2, Maud Wieczorek3, Jérémie sellam4, willy Ngueyon Sime5, Jacques Pouchot6, Christian Roux7, Alain SARAUX8, Francis Guillemin9 and Joel Coste10, 1Caen University hospital, UMR 1075 Caen normandy university, Caen, France, 2Rheumatology Department, Lariboisiere Hospital, Paris, France, 3Lausanne Univserty, Lausanne, Switzerland, 4Saint-Antoine hospital, Assistance Publique – Hôpitaux de Paris, Paris, France, Sorbonne University, Paris, France, 5CIC, Epidémiologie Clinique, CHRU-Nancy, Inserm, Université de Lorraine, Nancy, France, nNancy, France, 6HEGP hospital, Assistance Publique-Hopitaux de Paris,, Paris, France, 7CHU Nice, Nice, France, 8CHU Brest, Brest, France, 9CHU Nancy, Nancy, France, 10, Assistance Publique – Hôpitaux de Paris, Paris, France

    Background/Purpose: Few studies have examined how the quality of life (QoL) evolves in patients with osteoarthritis (OA) before undergoing total hip or total knee replacement…
  • Abstract Number: 0283 • ACR Convergence 2025

    The Performance of Rule-Based Algorithms to Identify Patients With Idiopathic Inflammatory Myopathies in Electronic Health Records

    Ana Valle1, Amy Vo2, Rochelle Castillo1, Yumeko Kawano3, Leah Santacroce3, Daniel Solomon4, Katherine Liao3 and Candace Feldman3, 1Brigham and Women's Hospital, Brookline, MA, 2Harvard Medical School, Boston, 3Brigham and Women's Hospital, Boston, MA, 4Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Idiopathic inflammatory myopathies (IIM; including dermatomyositis, polymyositis, and inclusion body myositis) are heterogenous systemic inflammatory conditions that cause significant disability and morbidity. The study…
  • Abstract Number: 0313 • ACR Convergence 2025

    People with Knee Osteoarthritis Infrequently Seek Medical Care for Arthritis, Even Those With Severe Disease

    Grace Lo1, Shunshun Yan2, Julieann Patarini3, Timothy McAlindon4, Charles Eaton5 and Jeffrey Driban6, 1Baylor College of Medicine / MEDVAMC, Houston, TX, 2Baylor College of Medicine, Houston, 3UMass Chan Medical School, Worcester, MA, 4UMass Chan School of Medicine, Arlington, MA, 5Brown University, Providence, RI, 6University of Massachusetts Chan Medical School, Marlborough, NH

    Background/Purpose: Osteoarthritis (OA) is the most common form of arthritis, a condition associated with substantial disability. Providers are often uncomfortable managing arthritis, and patients with…
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