ACR Meeting Abstracts

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  • Abstract Number: 1889 • ACR Convergence 2023

    Utility of a Diagnostic Algorithm in the Assessment of Large Vessel Vasculitis

    HUGO AVALOS BOGADO1, GUSTAVO AÑEZ STURCHIO2, Ernesto Trallero-Araguas3, Esther Espartal López4, sebastián Sandoval Moreno1, daniela Ulloa Navas5 and Juan José De Agustín De Oro2, 1Rheumatology Department Vall d'Hebrón University Hospital, Barcelona, Spain, 2Vall d'Hebron University Hospital, Barcelona, Spain, 3Systemic Autoimmune Disease Unit, Vall d’Hebron Institute of Research, Barcelona, Spain, 4Vall Hebron University Hospital, Rheumatology Department, Barcelona, Spain, 5Rheumatology Department, Vall Hebron University Hospital, Barcelona, Spain

    Background/Purpose: Giant cell arteritis (GCA) is the most prevalent type of primary systemic vasculitis among individuals aged 50 and above. Imaging techniques such as ultrasound…
  • Abstract Number: 1880 • ACR Convergence 2023

    Performance of Machine Learning Algorithms in Discriminating Spondyloarthritis Features on Magnetic Resonance Imaging: A Systematic Review and Meta-analysis

    Sun Jae Moon1, Seulkee Lee1, Seonyoung Kang1, Hyungjin Kim1, Jaejoon Lee1, Jinseok kim2, Eun-Mi Koh3, Jinseub Hwang4 and Hoon-Suk Cha1, 1Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 2Division of Rheumatology, Department of Internal Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, South Korea, 3Health Insurance Review and Assessment Service, Seoul, South Korea, 4Department of Data Science, Daegu University, Gyeongsan, South Korea

    Background/Purpose: The diagnostic role of Magnetic Resonance Imaging (MRI) for axial spondyloarthritis(axSpA) has grown since introducing the ASAS criteria for axSpA. Recent advances in machine…
  • Abstract Number: 1882 • ACR Convergence 2023

    Imaging in Diagnosis, Monitoring and Outcome Prediction of Large Vessel Vasculitis: A Systematic Literature Review Informing the 2023 Update of the EULAR Recommendations

    Philipp Bosch1, Milena Bond2, Christian Dejaco3, Cristina Ponte4, Sarah Mackie5, Louise Falzon6, Wolfgang Schmidt7 and Sofia Ramiro8, 1Medical University of Graz, Graz, Austria, 2Azienda sanitaria dell'Alto Adige, Merano, Italy, 3Department of Rheumatology, Medical University Graz, Graz, Austria; Department of Rheumatology, Hospital of Bruneck (ASAA-SABES), Teaching Hospital of the Paracelsius Medical University, Brunico, Italy, 4Department of Rheumatology, Centro Hospitalar Universitário Lisboa Norte, Centro Académico de Medicina de Lisboa, Lisbon, Portugal; Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Centro Académico de Medicina de Lisboa, Lisbon, Portugal, 5Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 6University of Sheffield, Sheffield, United Kingdom, 7Immanuel Krankenhaus Berlin, Berlin, Germany, 8Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Since the development of the EULAR recommendations for the use of imaging in large vessel vasculitis (LVV) in 2017, new data has emerged in…
  • Abstract Number: 1849 • ACR Convergence 2023

    Impact of the First Three Waves of the Covid-19 Pandemic on Everyday Restrictions and Clinical Care of Patients with Spondyloarthritis Across Europe – Results from the EuroSpA Collaboration

    Brigitte Michelsen1, Bente Glintborg2, Kim Lauper3, Bjorn Gudbjornsson4, Lykke Ørnbjerg5, Gerdur Maria Gröndal6, Karin Laas7, Sigrid Vorobjov8, Dan Nordstrom9, Heikki Relas9, Adrian Ciurea10, Burkhard Moeller11, Isabel Castrejon12, Lucia Otero-Valera13, Ziga Rotar14, Katja Perdan Pirkmajer15, Anne Gitte Loft16, Jakub Zavada17, Karel Pavelka18, Eirik Kristianslund19, Tore Kvien20, Marleen van de Sande21, Pasoon Hellamand22, Florenzo Iannone23, Roberto F. Caporali24, Ana Maria Rodrigues25, Maria Jose Santos26, Catalin Codreanu27, Corina Mogosan28, Merete Hetland5 and Mikkel Østergaard29, 1Rigshospitalet Glostrup; Diakonhjemmet Hospital; Sørlandet Hospital, Copenhagen, Denmark, 2Rigshospitalet Glostrup, University of Copenhagen, Virum, Denmark, 3Geneva University Hospitals, Genève, Switzerland, 4Centre for Rheumatology Research, University Hospital, Reykjavik, Iceland, 5Copenhagen Center for Arthritis Research, Rigshospitalet, Copenhagen, Denmark, 6Landspitali University Hospital; University of Iceland, Reykjavik, Iceland, 7Department of Rheumatology, East-Tallinn Central Hospital, Tallinn, Estonia, 8National Institute for Health Development, Tallinn, Estonia, 9Helsinki University Hospital, Helsinki, Finland, 10University Hospital Zurich, Zürich, Switzerland, 11Inselspital - University Hospital Bern, Bern, Switzerland, 12Hospital Universitario Gregorio Marañón, Madrid, Spain, 13Spanish Society of Rheumatology, Madrid, Spain, 14University Medical Centre Ljubljana, Ljubljana, Slovenia, 15University Medical Centre Ljubljana; University of Ljubljana, Ljubljana, Slovenia, 16Aarhus University, Horsens, Denmark, 17Institute of Rheumatology; Charles University, Prague, Czech Republic, 18Institut of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Praha, Czech Republic, 19Diakonhjemmet Hospital, Oslo, Norway, 20Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway, 21Amsterdam UMC, University of Amsterdam, Department of Rheumatology & Clinical Immunology and Department of Experimental Immunology, Amsterdam Infection & Immunity Institute; Amsterdam Rheumatology & Immunology Center (ARC), Academic Medical Center, Amsterdam, Netherlands, 22Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands, 23Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari "Aldo Moro", Bari, Italy, 24Department of Clinical Sciences and Community Health, University of Milan, and Department of Rheumatology and Medical Sciences, ASST Gaetano Pini-CTO, Milano, Italy, 25Sociedade Portuguesa de Reumatologia; Nova Medical School; Hospital dos Lusíadas, Lisbon, Portugal, 26Hospital Garcia de Orta, Almada, Lisboa, Portugal, 27Center for Rheumatic Diseases, Bucharest, Romania, 28University of Medicine and Pharmacy, Bucharest, Romania, 29Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet; University of Copenhagen, Copenhagen, Denmark

    Background/Purpose: The Covid-19 pandemic constituted major challenges for health-care services worldwide. We aimed to compare Covid-19 restrictions across Europe during the first three waves of…
  • Abstract Number: 1710 • ACR Convergence 2023

    Genetic Associations in Juvenile Idiopathic Arthritis Determined with an Electronic Health Record Based Approach

    Elizabeth Jasper, Srushti Gangireddy, Henry Ong, Jacklyn Hellwege, Todd Edwards, Digna Velez Edwards, Wei-Qi Wei and Anna Patrick, Vanderbilt University Medical Center, Nashville, TN

    Background/Purpose: Juvenile idiopathic arthritis (JIA) encompasses multiple forms of pediatric autoimmune arthritis. Research studies in JIA are complicated by disease heterogeneity and difficulties gathering large…
  • Abstract Number: 1055 • ACR Convergence 2023

    Cancer Outcomes in Cancer Patients with Immune Checkpoint Inhibitor-induced Inflammatory Arthritis Treated with Glucocorticoids: Data from the CanRIO Retrospective Cohort

    Vanissa Savarimuthu1, Alexandra Ladouceur2, Oliver Terry1, Janet Roberts3, Janet Pope4, Thomas Appleton4, Sabrina Hoa5, Aurore Fifi-Mah6, Nancy Maltez7, Alexandra Saltman8, Megan Himmel8, Ines Colmegna9, Lindsay Cho10, Emma Schmidt10, Claudie Berger11, Thomas Barnetche12, Lourdes Gonzalez Arreola13, Carrie Ye14, Shahin Jamal15 and Marie Hudson16, 1McGill University, Montreal, QC, Canada, 2Department of Rheumatology of McGill University and CHU-Bordeaux, Montréal, QC, Canada, 3Dalhousie University, Halifax, NS, Canada, 4University of Western Ontario, London, ON, Canada, 5University of Montreal, Brossard, QC, Canada, 6University of Calgary, Calgary, AB, Canada, 7The Ottawa Hospital, Ottawa, ON, Canada, 8University of Toronto, Toronto, ON, Canada, 9The Research Institute of the McGill University Health Centre, Montréal, QC, Canada, 10University of British Columbia, Vancouver, BC, Canada, 11RI-MUHC, Montreal, QC, Canada, 12Bordeaux University Hospital, Bordeaux, France, 13Arthritis Research Canada, Vancouver, BC, Canada, 14University of Alberta, Edmonton, AB, Canada, 15Vancouver Coastal Health, Vancouver, BC, Canada, 16McGill University, Montréal, QC, Canada

    Background/Purpose: Immune checkpoint inhibitors (ICI) have revolutionized the treatment of cancer. A drawback of ICI therapy is their off-target effects known as immune-related adverse events…
  • Abstract Number: 1454 • ACR Convergence 2023

    Neuropsychiatric Systemic Lupus Erythematosus in Children: A Scoping Review

    Alexandra Theisen1, Ekemini Ogbu2, Emily Beil3, Onengiya Harry4, Simone Appenzeller5, Ryan Kammeyer6, Hanne Van der Heijen7, Andrea Knight8, Hannah Craven9 and Martha Rodriguez10, 1Saint Louis University School of Medicine, SSM Health Cardinal Glennon Children's Hospital, St. Louis, MO, 2Cincinnati Children's Hospital Medical Center, University of Cincinnati School of Medicine, Johns Hopkins University, Cincinnati, OH, 3Baylor College of Medicine / Texas Children's Hospital, Houston, TX, 4Brenner Children's Hospital - Wake Forest Baptist Health, Winston-Salem, NC, 5UNICAMP, Campinas, Brazil, 6University of Colorado School of Medicine, Children's Hospital Colorado, Denver, CO, 7Boston Children's Hospital, Harvard Medical School, Boston, MA, 8The Hospital for Sick Children, Toronto, ON, Canada, 9Ruth Lilly Medical Library, Indiana University School of Medicine, Indianapolis, IN, 10Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN

    Background/Purpose: Neuropsychiatric systemic lupus erythematosus (NPSLE) remains a challenging entity to diagnose and treat. The clinical heterogeneity of NPSLE coupled with the difficulty with attribution…
  • Abstract Number: 1074 • ACR Convergence 2023

    Baseline Clinical Features, but Not Shared Epitope or HLA B27, Predict Severe Outcomes for Immune Checkpoint Inhibitor-induced Inflammatory Arthritis

    Laura Cappelli1, omer Kamal2, Michelle Jones3, Clifton Bingham4 and Ami Shah5, 1Johns Hopkins School of Medicine, Baltimore, MD, 2St. Agnes Hospital, Baltimore, MD, 3Johns Hopkins University School of Medicine, Baltimore, MD, 4Johns Hopkins University, Baltimore, MD, 5Department of Medicine, Division of Rheumatology, Johns Hopkins University School of Medicine, Ellicott City, MD

    Background/Purpose: Immune checkpoint inhibitors (ICI) can cause inflammatory arthritis (IA) of varying severity. Many patients with ICI-IA require immunosuppression beyond corticosteroids, but there is no…
  • Abstract Number: 1842 • ACR Convergence 2023

    Reduction in the Concomitant Ordering of Erythrocyte Sedimentation Rate and C-Reactive Protein Within the Rheumatology Clinics at an Academic Medical Center

    Ruchi Desai1, Nainesh Shah1, Ray Zhang1, Maria Bacalao2, Haidy Galous3, David Karp1 and Puneet Bajaj1, 1UT Southwestern Medical Center, Dallas, TX, 2UT Southwestern, Dallas, TX, 3UT Southwestern, Southlake, TX

    Background/Purpose: ESR and CRP are two laboratory values usedto assess inflammation. There is data to support that CRPis superior to ESR to detect/monitor inflammation or…
  • Abstract Number: 1721 • ACR Convergence 2023

    The Therapeutic Effects of Gingival Mesenchymal Stem Cells and Their Exosomes in a Chimeric Model of Rheumatoid Arthritis

    shane Bruckner1, Braden Zeno2, Vittoria Capria1, William Willis3, Latha Prabha Ganesan1 and wael Jarjour1, 1Ohio State University, Columbus, OH, 2Ohio State University, Upper Arlington, OH, 3Ohio State University, Reynoldsburg, OH

    Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that leads to progressive joint destruction involving multiple joints. There is a large body of…
  • Abstract Number: 1088 • ACR Convergence 2023

    Improving JIA Outcomes Assessments in a Large Pediatric Rheumatology Practice: A Fellow Quality Improvement Project

    Anna Costello1, Hallie Carol1, Dori Abel2, Sarah Bayefsky3, Sarah Capponi1, Adam Mayer1, Julia Rood1, Kirsten Spichiger1, Joshua Madas1, Lynsey Cecere1, Megan Roman1, Beth Rutstein4 and Jon Burnham2, 1Children's Hospital of Philadelphia, Philadelphia, PA, 2Children's Hospital of Philadelphia, Philadelphia, PA, 3University of Pennsylvania/Children's Hospital of Philadelphia, Philadelphia, PA, 4Division of Rheumatology at Children's Hospital of Philadelphia, Philadelphia, PA

    Background/Purpose: Juvenile idiopathic arthritis (JIA) is a chronic autoimmune disease that can result in long-term joint damage if inadequately treated. Collecting validated outcomes data at…
  • Abstract Number: 1463 • ACR Convergence 2023

    Predictors of Cognitive Impairment in Individuals with Systemic Lupus Erythematosus

    Alexandra Lee1, Sharon Phillips2 and Leslie Crofford3, 1Meharry Medical College, Nashville, TN, 2Vanderbilt University Medical Center, Nashville, TN, 3Vanderbilt University Medical Center, Melbourne, AR

    Background/Purpose: The purpose of this study was to investigate factors associated with objective cognitive impairment in patients diagnosed with Systemic Lupus Erythematous (SLE). Subjective complaints…
  • Abstract Number: 1839 • ACR Convergence 2023

    Value of Small Fiber Neuropathy in Fibromyalgia Patients in a Rheumatological Setting

    Styliani Tsiami1, Elena Enax-Krumova2, Dietrich Sturm3, Matthias Vorgerd2, Bjoern Buehring4, Juergen Braun5 and Xenofon Baraliakos1, 1Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 2Neurologische Klinik Universitätsklinikum Bergmannsheil Bochum, Ruhr-University Bochum, Bochum, Germany, 3Agaplesion Bethesda - Krankenhaus, Wuppertal, Klinik für Neurologie, Wuppertal, Germany, 4Krankenhaus St. Josef, Wuppertal, Klinik für Internistische Rheumatologie, Wuppertal, Germany, 5Ruhr-Universität Bochum and Rheumazentrum Ruhrgebiet, Herne, Germany

    Background/Purpose: Small fiber neuropathy (SFN), a polyneuropathy (PNP) affecting A-delta and C-fibers has been described in patients with fibromyalgia (FM). Different patterns of small fiber…
  • Abstract Number: 1848 • ACR Convergence 2023

    Demographic and Clinical Factors Associated with HPV Vaccination in Young Adults with Rheumatic Disease

    Caroline Siegel1, Lauren Robinson1, Deanna Jannat-Khah1, Avi Mikhaylov1, Nancy Pan1 and Lisa Sammaritano2, 1Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, Weill Cornell Medicine, New York, NY

    Background/Purpose: The HPV vaccine is safe and immunogenic in RD patients but uptake is suboptimal. We aimed to evaluate factors associated with HPV vaccination in…
  • Abstract Number: 1723 • ACR Convergence 2023

    3,3-dimethyl-1-butanol and Its Metabolite 3,3-dimethylbutyrate Ameliorate Arthritis Severity in CIA Independent of Choline TMA Lyase Activity

    Brendan Allen1, Sabrina Fechtner2, Meagan Chriswell3, Widian Jubair1, M. Aaron Vrolijk1, V. Michael Holers4 and kristine Kuhn1, 1University of Colorado School of Medicine, Aurora, CO, 2University of Colorado Anschutz Medical Campus, Aurora, CO, 3University of Colorado Anschutz SOM, Denver, CO, 4University of Colorado, Denver, CO

    Background/Purpose: Both human and animal studies associate specific microbiota and microbial metabolic pathways with the development of RA and autoimmune arthritis, thereby providing a novel…
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