Abstracts Archive - Page 266 of 2425 - ACR Meeting Abstracts

Abstract Number: 0800 • ACR Convergence 2023
CD4+ CD96+ T Cells Are Pathogenic Effector Cells in Giant Cell Arteritis
Shozo Ohtsuki¹, Jose Morales², Yuki Sato², Chenyao Wang², Matthew Koster³, Kenneth Warrington³, Gerald J. Berry⁴, Jorg Goronzy³ and Cornelia M. Weyand⁵, ¹Mayo Clinic College of Medicine and Science, Stanford University School of Medicine, Rochester, MN, ²Mayo Clinic College of Medicine and Science, Rochester, MN, ³Mayo Clinic, Rochester, MN, ⁴Stanford University School of Medicine, Stanford, CA, ⁵Mayo Clinic School of Medicine and Stanford University, Rochester, MN
Background/Purpose: In Giant Cell Arteritis (GCA), granulomatous infiltrates occupy the vessel wall and elicit maladaptive vascular remodeling with intimal hyperplasia. The major cell types of…
Abstract Number: 1516 • ACR Convergence 2023
Systemic Sclerosis Gastrointestinal Tract Vascular Biomarkers of Symptomatic Disease Activity
Venkateswara Gogulamudi¹, Sarah Wood², Elizabeth Johnson², Aaron Petrey³, Anthony Donato⁴ and Tracy Frech², ¹Salt Lake Veterans Affairs Medical Center, Salt Lake City, UT, ²Vanderbilt University Medical Center, Nashville, TN, ³University of Utah, Salt Lake City, UT, ⁴University of Utah and Salt Lake VAMC, Salt Lake City, UT
Background/Purpose: Gastrointestinal tract symptoms are common in systemic sclerosis (SSc). The Scleroderma Clinical Trials Consortium University of California Los Angeles Gastrointestinal Tract Questionnaire (GIT 2.0)…
Abstract Number: 1509 • ACR Convergence 2023
Calcineurin Inhibitors for Treatment of Lupus Nephritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Gabriel Figueroa-Parra¹, Maria Cuellar-Gutierrez¹, Mariana Gonzalez-Trevino¹, Larry J. Prokop², M. Hassan Murad³ and Ali Duarte-Garcia⁴, ¹Division of Rheumatology, Mayo Clinic, Rochester, MN, ²Mayo Clinic Libraries, Mayo Clinic, Rochester, MN, ³Evidence-based Practice Center, Mayo Clinic, Rochester, MN, ⁴Mayo Clinic, Rochester, MN
Background/Purpose: The current recommendations for the treatment of LN consider as the standard of care (SoC) the use of MMF or CYC. Considering the expanding…
Abstract Number: 1519 • ACR Convergence 2023
Renal Complications Following Autologous Stem Cell Transplantation for Systemic Sclerosis
Malcolm MacKenzie¹, Harry Atkins² and Nancy Maltez¹, ¹The Ottawa Hospital, Ottawa, ON, Canada, ²Ottawa Hospital Research Institute, Ottawa, ON, Canada
Background/Purpose: Rapidly progressive diffuse systemic sclerosis (SSc) is a devastating autoimmune disease with high morbidity and mortality. Autologous hematopoietic stem cell transplantation (AHSCT) is recognized…
Abstract Number: 1521 • ACR Convergence 2023
Microvascular Remodeling After Autologous Stem Cell Transplant for Systemic Sclerosis
Lisa Balistreri¹, Megan Sullivan¹, Florentina Berianu¹, Ernesto Ayala² and Andy Abril², ¹Mayo Clinic Florida, Jacksonville, FL, ²Mayo Clinic, Jacksonville, FL
Background/Purpose: Autologous hematopoietic stem cell therapy (HSCT) is an effective therapy for patients with rapidly progressive systemic sclerosis (SSc) refractory to standard therapies. The disease…
Abstract Number: 1396 • ACR Convergence 2023
Comprehensive Evaluation of the Digital Annular Pulleys: From Ultrasonographical to Anatomical and Histological Evaluation with Special Focus on the Entheses
Luis Coronel¹, Peter Mandl², María Isabel Miguel³, Joan Blasi⁴, Maria Lopez-Lasanta¹, Sara Marsal¹, Maria-Antonietta D'Agostino⁵ and Ingrid Moller⁶, ¹Hospital Universitari Vall d'Hebron, Rheumatology, Barcelona, Spain, ²Department of Rheumatology, Medical University of Vienna, Vienna, Austria, ³Universitat de Barcelona - Campus Bellvitge, Unitat d’anatomía i embriología humana, L'Hospitalet de Llobregat, Barcelona, Spain, ⁴Universitat de Barcelona - Campus Bellvitge, Histologia, L'Hospitalet de Llobregat, Barcelona, Spain, ⁵Universita Cattolica del Sacro Cuore Rome, Courbevoie, France, ⁶Instituto Poal de Reumatología, Barcelona, Spain
Background/Purpose: The digital annular pulleys (DAP) are anatomical structures of soft connective tissue organized as transverse fibers of variable width, thickness, and configuration that overlay…
Abstract Number: 0973 • ACR Convergence 2023
Real-World Comparative Effectiveness Study of Janus Kinase Inhibitors Compared to Biologic Disease Modifying Antirheumatic Drugs in Korean Patients with Rheumatoid Arthritis
Soo-Kyung Cho¹, Yeo-Jin Song¹, Jungyong Han², Hye Won Kim³, Eunwoo Nam³, Sang Won Lee⁴, Shin-Seok Lee⁵, Hye-Soon Lee⁶, Sung-Hoon Park⁷, Yeon-Ah Lee⁸, Sung Hae Chang⁹, Min-Chan Park¹⁰, Hyoun-Ah Kim¹¹, Hyun-Sook Kim¹², Bo Young Yoon¹³, Yong-Gil Kim¹⁴, Hae-Rim Kim¹⁵, Jae Hoon Kim¹⁶, Jisoo Lee¹⁷, Jeongim Choi¹⁸, Wan-Sik Uhm¹⁹ and Yoon-Kyoung Sung¹, ¹Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ²Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ³Hanyang University Institute for Rheumatology Research, Seoul, South Korea, ⁴Hanyang University, Seoul, South Korea, ⁵Chonnam National University Medical School & Hospital, Gwangju, South Korea, ⁶Hanyang University, Guri, South Korea, ⁷Daegu Catholic University School of Medicine, Daegu, South Korea, ⁸Kyung Hee University Hospital, Seoul, South Korea, ⁹Soonchunhyang University College of Medicine, Bongmyeong-dong, Dongnam-gu, Cheonan-si, South Korea, ¹⁰Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea, ¹¹Ajou University School of Medicine, Suwon, South Korea, ¹²Soonchunhyang University Seoul Hospital, Seoul, South Korea, ¹³Inje University Ilsan Paik Hospital, Goyang, South Korea, ¹⁴Department of Rheumatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea, ¹⁵Rheumatology, Konkuk University Medical Center, Seoul, South Korea, ¹⁶Korea University Medical Center, Seoul, South Korea, ¹⁷Ewha Womans Univ College of Medicine, Seoul, South Korea, ¹⁸Busan Saint Mary's Hospital, Busan, South Korea, ¹⁹Uhm's Rheumatism Clinic, Seoul, South Korea
Background/Purpose: Although clinical trials have shown similar effectiveness between Janus kinase inhibitors (JAKi) and biologic disease-modifying anti-rheumatic drugs (bDMARDs), the choice between these two options…
Abstract Number: 0916 • ACR Convergence 2023
Upregulation of the M-CSF Receptor on Non-Classical Monocytes from SLE Patients as an Indicator for Premature Monocyte Aging
Markus Zeisbrich¹, Stephanie Finzel², Nils Venhoff¹ and Reinhard Voll¹, ¹University Medical Center Freiburg, Freiburg, Germany, ²Department of Rheumatology and Clinical Immunology, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany
Background/Purpose: Circulating monocytes are divided into three subsets: classical, intermediate, and non-classical monocytes. Monocytes egress from the bone marrow as classical monocytes and develop into…
Abstract Number: 1137 • ACR Convergence 2023
Association Between Nailfold Videocapillaroscopy Findings and sKL-6 Levels in Patients with Idiopathic Inflammatory Myopathies–Related Interstitial Lung Disease
Cristiana Sieiro Santos¹, Jose Luis Tandaipan², Diego Castillo², Laura Martínez Martínez², Helena Codes², Luis Sainz-Comas², Berta Paula Magallares-Lopez³, Patricia Moya², Anais Mariscal², Hye Sang Park², Ana Milena Millán Arciniegas², César Díaz-Torné², Ana Laíz Alonso², Sandra Ros², Susana Fernández², Hector Corominas⁴, Elvira Díez Álvarez⁵ and Iván Castellvi², ¹Complejo Asistencial Universitario de León, León, Spain, ²Hospital de Santa Creu i Sant Pau, Barcelona, Spain, ³Department of Rheumatology, Hospital de la Santa Creu I Sant Pau, Barcelona, Spain, ⁴Hospital Universitario Sant Pau, Rheumatology, Barcelona, Spain, ⁵CAULE, León, Spain
Background/Purpose: Interstitial lung disease (ILD) is a frequent pulmonary manifestation in idiopathic inflammatory myopathies (IIM) (IIM-ILD) and considerably influences morbidity and mortality. Krebs von den…
Abstract Number: 1517 • ACR Convergence 2023
Comparing Deep Neural Network to Modified Rodnan Skin Score in a Trial for Belumosudil in Systemic Sclerosis Patients
Baran Gunes¹, Lucy Duran Camacho¹, Shawn Cowper², Gauri Panse², Elizabeth Bundschuh³, Alyssa Williams⁴, Nicolas Page⁵, Mary Karns⁶, Kathleen Aren⁶, Niki Pradhan⁷, Elana Bernstein⁸, Sarah Fantus⁹, Elizabeth Volkmann¹⁰, Heather Bukiri¹⁰, Chase Correia¹¹, Francis Wilson¹, Seamus Mawe¹², J. Matthew Mahoney¹³, Monique Hinchcliff¹⁴ and Rui Wang¹⁵, ¹Yale University School of Medicine, New Haven, CT, ²Yale School of Medicine - Dermatopathology, New Haven, CT, ³Yale University School of Medicine, New York, NY, ⁴Yale University School of Medicine, Winchester, MA, ⁵Yale University School of Medicine, Salem, CT, ⁶Northwestern University Division of Rheumatology, Chicago, IL, ⁷Columbia University Irving Medical Center, New York, NY, ⁸Division of Rheumatology, Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, ⁹Kansas City Physician Partners- Center for Rheumatic Disease, Kansas City, MO, ¹⁰University of California Los Angeles, Los Angeles, CA, ¹¹Riverside Medical Group, Hampton, VA, ¹²The Jackson Laboratory, Bar Harbor, ME, ¹³Jackson Laboratory, Bar Harbor, ME, ¹⁴Yale School of Medicine, Westport, CT, ¹⁵Sanofi, Cambridge, MA
Background/Purpose: We previously published a proof-of-principle study demonstrating the potential utility of computer vision (Deep Neural Network/DNN) methods applied to stained skin biopsy sections from…
Abstract Number: 1376 • ACR Convergence 2023
SJOGRENSER Registry: Prospective Evaluation of a Cohort of Patients with Primary Sjögren’s Syndrome After 8 Years of Follow-up
Mónica Fernández-Castro¹, Zulema Plaza², Jose Rosas³, Victor Martinez-Taboada⁴, Alejandro Olivé⁵, Raúl Menor-Almagro⁶, SARA MANRIQUE⁷, Ruth López-González⁸, Celia Erausquin⁹, Antonio Naranjo⁹, Rocío Caño-Alameda¹⁰, Silvia Gómez-Sabater¹⁰, Jesús Alberto García Vadillo¹¹, Belen Serrano Benavente¹², Sheila Melchor¹³, Paula V. Estrada-Alarcón¹⁴, Angel Garcia-Aparicio¹⁵, Cristina Bohorquez¹⁶, Enrique Júdez¹⁷, Ximena Larco¹⁸, Javier Loricera¹⁹, Nerea Alcorta Lorenzo²⁰, Beatriz Paredes Romero²¹, Jorge González Martín²², María Ángeles Blázquez Cañamero²³, Consuelo Ramos-Giráldez²⁴, Fernando Alonso²⁵, Marta Domínguez²⁶ and Jose Luis Andreu-Sánchez²⁷, ¹Rheumatology Department Hospital Puerta de Hierro Majadahonda, Majadahonda, Spain, ²Universidad Autónoma de Madrid, Madrid, Spain, ³Hospital Marina Baixa, Alicante, Spain, ⁴Rheumatology, Hospital Marqués de Valdecilla, Santander, Spain, ⁵Rheumatology Department Hospital Germans Trias i Pujol, Badalona, Spain, ⁶Rheumatology, Hospital Jerez, Puerto De Santa María, Spain, ⁷Division of Rheumatology, Hospital Regional Universitario Carlos Haya, Malaga, Spain, ⁸Rheumatology Department Hospital Virgen de la Concha, Zamora, Spain, ⁹Rheumatology Department Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas de Gran Canaria, Spain, ¹⁰Rheumatology Department, Dr. Balmis University General Hospital, Alicante. Institute for Health and Biomedical Research (ISABIAL), Alicante, Spain, ¹¹Rheumatology Department Hospital de la Princesa, Madrid, Spain, ¹²Rheumatology Department Hospital Gregorio Marañón, Madrid, Spain, ¹³Rheumatology Department Hospital Doce de Octubre, Madrid, Spain, ¹⁴Hospital de San Juan Despí Moisès Broggi, Barcelona, Spain, ¹⁵Hospital Universitario de Toledo, Toledo, Spain, ¹⁶Rheumatology Unit, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Spain, ¹⁷Rheumatology Department Hospital de Albacete, Albacete, Spain, ¹⁸Rheumatology Department Hospital de León, León, Spain, ¹⁹Hospital Universitario Marqués de Valdecilla, Santander, Spain, ²⁰University Hospital Donostia, San Sebastian, Spain, ²¹Rheumatology Department Hospital Infanta Sofía, San Sebastian de los Reyes, Spain, ²²Rheumatology Department Hospital Madrid Norte Sanchinarro, Madrid, Spain, ²³Rheumatology Department Hospital Ramon y Cajal, Madrid, Spain, ²⁴Rheumatology Department Hospital Universitario Virgen de Valme, Sevilla, Spain, ²⁵Spanish Society of Rheumatology, Madrid, Spain, ²⁶Sociedad Española de Reumatología, Madrid, Spain, ²⁷Rheumatology, Hospital Universitario Puerta de Hierro, Majadahonda, Spain
Background/Purpose: Describe the evolution of patients with Sjögren's syndrome (SS) in relation to the appearance of new systemic manifestations and disease activity, as well as…
Abstract Number: 0365 • ACR Convergence 2023
Establishing a Multidisciplinary Registry for Temporomandibular Joint Arthritis in Juvenile Idiopathic Arthritis: Insights into Patient Outcomes and Management Challenges
Stacey Tarvin¹, Amy Rakestraw², Jessica Lee², N. Shaun Matthews³, Susan H. Ballinger² and Christina M. Sparks², ¹Riley Hospital for Children at Indiana University Health, Indianapolis, IN, ²Indiana University School of Medicine, Indianapolis, IN, ³Indiana University School of Dentistry, Indianapolis, IN
Background/Purpose: Temporomandibular joint (TMJ) arthritis, a condition frequently overlooked in patients with JIA, can result in joint damage if not promptly treated. Such damage presents…
Abstract Number: 1504 • ACR Convergence 2023
Characteristics and Prior Treatment Journey of Systemic Lupus Erythematosus (SLE) Patients Who Were Prescribed Anifrolumab — Observations from the American Rheumatology Network (ARN) in the U.S
Vasileios Kyttaris¹, Gelareh Atefi², Daniel Persons³, Christopher S. Ambrose⁴, Scott Milligan⁵ and Sandra Wu⁶, ¹BIDMC, Boston, MA, ²BioPharmaceuticals Medical, AstraZeneca, Wilmington, DE, ³Trio Health, Denver, CO, ⁴AstraZeneca, Wilmington, DE, ⁵Trio Health, Analytics, Louisville, CO, ⁶AstraZeneca, Hockessin, DE
Background/Purpose: FDA-approved for moderate-severe SLE in August 2021, anifrolumab is a type I interferon (IFN) receptor antagonist that has been shown to decrease lupus flares…
Abstract Number: 1398 • ACR Convergence 2023
A Deep Learning Algorithm for MRI Spinal Inflammation in Axial Spondyloarthritis
Shirley Chiu Wai Chan¹, Ying Ying Lin², Ho Yin Chung¹, Kam Ho Lee³ and Peng Cao², ¹Divison of Rheumatology and Clinical Immunology, Department of Medicine, Queen Mary Hospital, the University of Hong Kong, Hong Kong, Hong Kong, ²Department of Diagnostic Radiology, the University of Hong Kong, Hong Kong, Hong Kong, ³Department of Radiology, Queen Mary Hospital, Hong Kong, Hong Kong, Hong Kong
Background/Purpose: Deep learning has achieved wide applications in different areas of medical imaging analysis. Limited studies have explored the use of deep learning for imaging…
Abstract Number: 1148 • ACR Convergence 2023
A Comparative Study of Clinical Phenotype in Relation to NOD2 Sub-genotypes in Yao Syndrome
Ashmia Saif¹, Hafsa Nomani², Frank Hwang², Jie Yang² and Qingping Yao², ¹Stony Brook University Hospital, Syosset, NY, ²Stony Brook University, Stony Brook, NY
Background/Purpose: Yao syndrome (YAOS, OMIM 617321) is formerly designated NOD2-associated autoinflammatory disease. A spectrum of NOD2 mutations have been associated with this disease. Most patients…

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