ACR Meeting Abstracts

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  • Abstract Number: 0289 • ACR Convergence 2025

    Standardized Interoperable Data Collection for Myositis Research: Developing Common Data Elements for Myositis Disease Activity Core Set Measures

    Didem Saygin1, Matthew Diller2, Varsha Surampudi3, Mark Bodkin3, Payam Farhadi4, Adam Schiffenbauer5, Audrey Kessel3, Chris Mecoli6, Rohit Aggarwal7, Helene Alexanderson8, Michelle Best9, Olivier Benveniste10, Hector Chinoy11, Brian Feldman12, Linda Kobert13, Manuel Lubinus14, Liza McCann15, Chester V. Oddis16, Nicolino Ruperto17, Jens Schmidt18, Victoria Werth19, Christie Bartels20, Hanna Kim21, Andrew Mammen22, Julie Paik23, Ellen M. Werner13, Ingrid de Groot24, Pedro Machado25, Susan Kim26, Tahseen Mozaffar27, Adam M Huber28, Angelo Ravelli29, Richard Scheuermann2 and Lisa Rider30, 1Rush University Medical Center, Chicago, IL, 2National Library of Medicine, National institutes of Health, Bethesda, MD, 3Social Scientific System Inc, a DLH holding company, Baltimore, MD, 4National Institutes of Health/National Institute of Environmental Health Sciences, Bethesda, MD, 5National Institute of Health/National Institute of Dental and Craniofacial Research, Bethesda, MD, 6Johns Hopkins University School of Medicine, Baltimore, MD, 7University of Pittsburgh, Rheumatology and Clinical Immunology, Pittsburgh, United States of America, Pittsburgh, PA, 8Karolinska University Hospital, Stockholm, Sweden, 9Cure JM Foundation, Lessburg, VA, 10Sorbonne Uniersite, Hopital de la Pitie-Salpetriere, Paris, France, 11The University of Manchester, Manchester, United Kingdom, 12The Hospital for Sick Children, Toronto, ON, Canada, 13The Myositis Association, Columbia, MD, 14Myositis Support and Understanding, Lincoln, DE, 15Alder Hey Children's NHS Foundation Trust, Liverpool, United Kingdom, 16University of Pittsburgh, Pittsburgh, PA, 17Université Milano Bicocca and Fondazione IRCSS S. Gerardo dei Tintori, Monza, Monza and Brianza, Italy, 18Immanuel University Hospital Ruedersdorf, Brandenburg Medical School, Rudersdorf, Germany, 19University of Pennsylvania, Philadelphia, PA, 20University of Wisconsin School of Medicine and Public Health, Madison, WI, 21NIAMS, NIH, Bethesda, MD, 22NIH, Bethesda, MD, 23Johns Hopkins Rheumatology, Baltimore, MD, 24The Myositis Association, Rotterdam, Netherlands, 25University College London, London, United Kingdom, 26UCSF Benioff Children's Hospital, San Francisco, CA, 27University of California, Irvine, Orange, CA, 28IWK Grace Health Centre, Halifax, NS, Canada, 29IRCCS Istituto Giannina Gaslini, Genoa, Italy, Genoa, Genoa, Italy, 30National Institute of Environmental Health Sciences/National Institutes of Health, Environmental Autoimmunity Group, Bethesda, MD

    Background/Purpose: Recent progress has been made in developing myositis outcome assessments, response and classification criteria, and consensus in the design and conduct of clinical trials…
  • Abstract Number: 0280 • ACR Convergence 2025

    Sera from dermatomyositis patients induce muscle weakness via activation of type I interferon (IFN) receptors.

    Suchada Kaewin1, Cecilia Leijding2, Kristofer Andreasson2, Helene Alexanderson3, Stefano Gastaldello1, Ingrid Lundberg2 and Daniel C. Andersson2, 1Karolinska Institutet, inst fysiologi och farmakologi, Stockholm, Sweden, 2Karolinska Institutet, Stockholm, Sweden, 3Karolinska University Hospital, Stockholm, Sweden

    Background/Purpose: Dermatomyositis (DM) is a major subtype of idiopathic inflammatory myopathies (IIMs) and characterized by muscle weakness, systemic inflammation and cutaneous lesions. Expression of type…
  • Abstract Number: 0290 • ACR Convergence 2025

    Comparison of Organ Damage and Survival in Anti-synthetase Syndrome and Other Idiopathic Inflammatory Myopathies: An Analysis of Patients from Turkey

    Ezgi Sahin1, Omer Uludag2, yasemin yalcinkaya3, Bahar Artim Esen4, Ahmet Gul3 and Murat Inanc3, 1Istanbul University Istanbul Faculty of Medicine, Istanbul, Turkey, 2Istanbul University, Istanbul Faculty of Medicine, Division of Rheumatology, Istanbul, Turkey, 3Istanbul University, Istanbul Faculty of Medicine, Division of Rheumatology, Istanbul, Istanbul, Turkey, 4Istanbul University, Istanbul, Istanbul, Turkey

    Background/Purpose: Idiopathic inflammatory myopathies (IIMs) are rare autoimmune diseases characterized by muscle weakness, often involving other organs such as the skin, lungs, and heart. Defined…
  • Abstract Number: 0258 • ACR Convergence 2025

    Performance characteristics of anti-Collagen II antibodies for diagnosing inflammatory and non-inflammatory diseases: a systematic review and meta-analysis

    Karyssa Stonick1, Marcela ferrada2, Alice Fike3, Kaitlin Quinn3, Benjamin Turturice3, Casey Stein4 and Peter Grayson5, 1National Insitute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, 2University of Maryland, Bethesda, MD, 3National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, 4NIAMS, NIH, Chevy Chase, MD, 5National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Chevy Chase, MD

    Background/Purpose: Anti-collagen II (Col2) antibodies have been clinically and experimentally associated with relapsing polychondritis (RP), rheumatoid arthritis (RA), and other diseases. Whether anti-Col2 antibodies are…
  • Abstract Number: 0194 • ACR Convergence 2025

    Evaluation of a Home-based Therapeutics Service: Feasibility, Patient and Caregiver Experience, and Cost

    Xiaohui Xin, Andrea Low, Sow Ling Yee, Miao Miao Liu, Christina Tan, Daphne Ng and Siaw Ing Yeo, Singapore General Hospital, Singapore, Singapore

    Background/Purpose: The home-based therapeutics service (HTS) by a community nurse is part of an ongoing larger initiative—Community Therapeutics Programme (CTP)—spearheaded by the Rheumatology and Immunology…
  • Abstract Number: 0242 • ACR Convergence 2025

    Contemporary Recurrent Pericarditis Management – Real-world Evidence of Limited Cardiac Magnetic Resonance Imaging Prior to Initiating Rilonacept

    Brittany Weber1, Paul Cremer2, Michael Garshick3, Sushil Allen Luis4, Ajit Raisinghani5, Vidhya Parameswaran6, Allison Curtis6, Allan Klein7 and John Paolini6, 1Brigham and Women's Hospital, DEDHAM, MA, 2Cleveland Clinic, Shaker Heights, OH, 3NYU Langone Health, Tenafly, NJ, 4Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, 5Division of Cardiology, Department of Medicine, Sulpizio Cardiovascular Center, University of California San Diego, San Diego, CA, 6Kiniksa Pharmaceuticals, LEXINGTON, MA, 7Cleveland Clinic, Cleveland, OH

    Background/Purpose: Recurrent pericarditis (RP) is a chronic autoinflammatory disease (mediated by IL-1) that requires long-term treatment, and selection of therapy is guided by multiple factors.…
  • Abstract Number: 0235 • ACR Convergence 2025

    Mortality Trends due to Hypertension Related Deaths in Elderly Patients with Inflammatory Polyarthropathy: A CDC WONDER Analysis of 21 Years

    ZAUHA FAWAD MEMON1, Sibgha Fawad Memon2, Matia Fawad Memon2, REHAN ISHAQUE3, AHMAD SANAN4 and MUHAMMAD MUGHEES5, 1Peoples University of Medical and Health Sciences for Women, Tando Allahyar, Sindh, Pakistan, 2Peoples University of Medical and Health Sciences for Women, Tando Allahyar, Pakistan, 3LIAQUAT UNIVERSITY OF MEDICAL AND HEALTH SCIENCES, Jam Shoro, Sindh, Pakistan, 4KHYBER MEDICAL COLLEGE, Peshawer, Pakistan, 5Bahria University health Sciences, KARACHI, Pakistan

    Background/Purpose: Inflammatory polyarthropathy (IPA) is a group of chronic autoimmune disorders, common among older adults and contribute significantly to systemic inflammation and cardiovascular risk .…
  • Abstract Number: 0161 • ACR Convergence 2025

    Risk Factors and Clinical Predictors of Lung Cancer in Systemic Sclerosis: A Matched Case-Control Study from a Michigan Cohort

    Madiha Naqsh Siddiqui1, Yen Chen1, Rosemary Gedert2, Suiyuan Huang2, Dinesh Khanna2 and John Varga2, 1University of Michigan, Ann Arbor, 2University of Michigan, Ann Arbor, MI

    Background/Purpose: Malignancies are one of the leading causes of non-systemic sclerosis-related mortality in patients with systemic sclerosis (SSc)1, with lung cancer being the most common…
  • Abstract Number: 0234 • ACR Convergence 2025

    Use of Corneal Confocal Microscopy to Assess Small Fiber Neuropathy in Patients with Sarcoidosis

    Philip Bucur1, Kelly Gwathmey2, Huzaefah Syed2, Aamer Syed2, Thomas Iden3, Neha Gupta2, Jessica McLaughlin2, Jordana Kron2, Ryan Canissario2, Shanshan Chen1, Hoda Gad4, Rayaz Malik4, Sai Patel2 and Vaishali Patel2, 1VCU Health, Richmond, VA, 2Virginia Commonwealth University Medical Center, Richmond, VA, 3Virginia Commonwealth University Medical Center, Richmond, 4Weill Cornell Medicine-Qatar, Doha, Qatar

    Background/Purpose: Small fiber neuropathy (SFN) is a common complication of sarcoidosis, affecting about one third of patients. The current gold standard for diagnosis combines patient…
  • Abstract Number: 0216 • ACR Convergence 2025

    Evaluation of oral treatment adherence in Systemic Lupus Erythematosus patients: indentification of risks profiles

    Carmen Lasa Teja1, Carolina Aguirre-Portilla2, Virginia Portilla González3, Carmen Bejerano-Herreria2, Alfonso Corrales-Martínez4 and Ricardo Blanco5, 1Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain., Riotuerto, Cantabria, Spain, 2Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander , Spain, Santander, Spain, 3Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander , Spain, Santander, 4Department of Rheumatology, Hospital Universitario Marqués de Valdecilla, Santander, Spain, Santander, Spain, 5Rheumatology Division, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain, Santander, Cantabria, Spain

    Background/Purpose: Systemic Lupus Erythematosus (SLE) is a chronic and complex autoimmune disease that requires adequate treatment adherence to control disease activity and prevent complications. However,…
  • Abstract Number: 0127 • ACR Convergence 2025

    Single-cell Profiling of Dermal Endothelial Cells Reveals Potential Cell-Cell Interactions in Patients with APS and a History of Cardiac Valve Disease

    Wenying Liang1, Qinmengge Li2, Jacqueline Madison1, Ran Jing1, Emily Chong1, Yiran Shen1, Rachael Bogle3, Srilakshmi Yalavarthi1, Cyrus Sarosh4, Ajay Tambralli1, Yu (Ray) Zuo1, Johann Gudjonsson1, Hui Shi5, Pei-Suen Tsou1, Alex Tsoi3 and Jason S. Knight1, 1University of Michigan, Ann Arbor, MI, 2University of Michigan, Ypsilanti, MI, 3University of Michigan, Holland, OH, 4University of Michigan, Temperance, MI, 5Shanghai Jiaotong University Affiliated Ruijin Hospital, Shanghai, China (People's Republic)

    Background/Purpose: Some of the rarer manifestations of antiphospholipid syndrome (APS), such as cardiac valve disease, remain poorly understood at the molecular level. A previous study…
  • Abstract Number: 0217 • ACR Convergence 2025

    Development of the American College of Rheumatology Implementation Guide for Integrating Patient Reported Systemic Lupus Erythematosus Quality Measures

    Catherine Nasrallah1, Christine Hariz2, Shanthini Kasturi3, Wambui Machua4, Jinoos Yazdany5, Christie Bartels6, Kate Chiseri7, Starla Blanks7, Patti Katz8, Cherish Wilson9, April Jorge10, Beth Radtke11, Tom Tack7 and Shivani Garg12, 1University of California San Francisco (UCSF), San Francisco, CA, 2University of California San Francisco (UCSF, San Francisco, CA, 3Tufts Medical Center, Boston, MA, 4Piedmont Healthcare, Atlanta, GA, 5UCSF, San Francisco, CA, 6University of Wisconsin School of Medicine and Public Health, Madison, WI, 7American College of Rheumatology, Atlanta, GA, 8UCSF, San Rafael, CA, 9UCSF / SFVA, San Francisco, CA, 10Massachusetts General Hospital, Boston, MA, 11ACR, Atlanta, GA, 12University of Madison, School of Medicine and Public Health, Madison, WI

    Background/Purpose: Systemic lupus erythematosus (SLE) is a complex disease that presents unique care challenges. To improve high-quality patient-centered care, the American College of Rheumatology (ACR),…
  • Abstract Number: 0238 • ACR Convergence 2025

    Real-World Effectiveness of Mepolizumab on Gastrointestinal Involvement in Eosinophilic Granulomatosis with Polyangiitis and Hypereosinophilic Syndrome: A Multicenter Retrospective Study

    Alessia Gatti1, Francesca Regola1, Giulia Fontana2, Jacopo Mora2, Mario Andrea Piga3, Gianluca Moroncini3, Rossella Acquaviva4, Palma Carlucci4, Silvia Noviello4, Angelo Vacca4, Paolo Delvino5, Enrico Heffler6, Emanuele Nappi6, Jakub Moll7, Jan Schroeder7, Laura Losappio7, Federica Davanzo8, Roberto Padoan9, Paolo Cameli10, Edoardo Conticini11, Greta Pacini12, Alvise Berti12, Lorenzo Vrola13, Paola Tomietto13, Benedetta Fazzi14, elena treppo15, Luca Quartuccio14, Jan Willem Cohen Tervaert16, Sabrina Arnold17, Prof. Dr. med. Peter Lamprecht18, Florence Roufosse19, Ilaria Cavazzana1, Franco Franceschini20, Giacomo Emmi21 and Paola Toniati22, 1Rheumatology and Clinical Immunology Unit – ERN ReCONNET, ASST Spedali Civili of Brescia and University of Brescia, Brescia, Italy, 2Rheumatology and Clinical Immunology Unit – ERN ReCONNET, ASST Spedali Civili and University of Brescia, Brescia, Lombardia, Italy, 3Università Politecnica delle Marche and Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy, 4Section of Internal Medicine 'Guido Baccelli', Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari 'Aldo Moro', Bari, Italy, 5Rheumatology Unit, IRCCS San Gerardo dei Tintori, Monza, Italy, 6Department of Biomedical Sciences, Humanitas University, Pieve Emanuele (MI) and Personalized Medicine, Asthma and Allergy, IRCCS Humanitas Research Hospital, Milano, Italy, 7Division of Allergy and Clinical Immunology, ASST GOM Niguarda, Milano, Italy, 8Rheumatology Unit, Department of Medicine DIMED, University of Padua, Padova, Italy, 9Rheumatology Unit, Department of Medicine DIMED, University of Padua, Padua, Italy, 10University of Siena, Siena, Italy, 11Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Italy, Siena, Italy, 12Santa Chiara Hospital and University of Trento, Unit of Rheumatology, Trento, Italy, 13UCO Medicina Clinica, ASUGI, Cattinara Teaching Hospital, Trieste, Italy, 14Division of Rheumatology, Department of Medicine (DMED), University of Udine, Udine, Italy, 15Division of Rheumatology, Department of Medicine, University of Udine, Udine, Italy, 16University of Alberta, Edmonton, AB, Canada, 17Department of Rheumatology and Clinical Immunology, University of Lübeck, Lubeck, Germany, 18University of Lübeck, Lübeck, Germany, 19Department of Internal Medicine, Hôpital Universitaire de Bruxelles - Erasme, Université Libre de Bruxelles, Bruxelles, Belgium, 20University of Brescia, Brescia, Brescia, Italy, 21Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy, 22Rheumatology and Clinical Immunology Unit – ERN ReCONNET, ASST Spedali Civili of Brescia, Brescia, Lombardia, Italy

    Background/Purpose: Eosinophilic gastrointestinal disorders (EGIDs) are a group of disorders characterized by marked eosinophilic infiltration of the gastrointestinal (GI) tract resulting in organ dysfunction and…
  • Abstract Number: 0209 • ACR Convergence 2025

    A Retrospective Safety Analysis based on Platelets in Arthrocentesis and Joint injections in Cancer Patients

    Yuanteng Li1, Cheuk Leung2, Heather Lin2, Angeles Lopez-Olivio3 and Jean Tayar3, 1MD Anderson Cancer Center, Houston, TX, 2MD Anderson Cancer Center, Houston, 3The University of Texas, MD Anderson Cancer Center, Houston, TX

    Background/Purpose: Arthrocentesis and joint injections are commonly performed to diagnose and to treat rheumatic conditions such as crystal-induced arthritis, septic arthritis, and inflammatory arthritis. While…
  • Abstract Number: 0349 • ACR Convergence 2025

    Underrecognized Glucocorticoid-Induced Osteoporosis in a Polymyalgia Rheumatica Patient Cohort

    katherine Loomba1, Emily Campbell1, Nisha Khubchandani1, chih Fang1, William Rigby2 and Vivekanand Tiwari1, 1Dartmouth Hitchcock Medical Center, Lebanon, NH, 2Dartmouth-Hitchcock, Norwich, VT

    Background/Purpose: Polymyalgia Rheumatica (PMR) and Giant Cell Arteritis (GCA) are systemic inflammatory disorders treated with prolonged corticosteroid therapy. Prolonged use of corticosteroids is a significant…
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