Abstracts Archive - Page 2598 of 2607 - ACR Meeting Abstracts

Abstract Number: 74 • 2012 ACR/ARHP Annual Meeting
Length of Stay for Rheumatoid Arthritis Related Orthopedic Surgery Has Improved Over the Past 3 Decades and Is Related to Disease Markers. Results From Two UK Multicentre Inception Cohorts (1986-2011) Compared with National Data
Elena Nikiphorou¹, Stephen Morris², David James³, Patrick D. Kiely⁴, David Walsh⁵ and Adam Young⁶, ¹Research Department of Epidemiology & Public Health, UCL and Rheumatology, St Albans City Hospital, ERAS, St Albans City Hospital and University College London (UCL), St Albans, United Kingdom, ²Epidemiology and Public Health, Research Department of Epidemiology and Public Health, 1-19 Torrington Place, United Kingdom, ³Rheumatology, Diana Princess of Wales Hospital, Grimsby, United Kingdom, ⁴Rheumatology Dept, St. Georges Hospital, London, United Kingdom, ⁵Academic Rheum/Clin Sci Bldg, City Hospital, Nottingham, United Kingdom, ⁶Rheumatology, ERAS, St Albans City Hospital, St Albans, United Kingdom
Background/Purpose: Length of Stay (LoS) is one of the main drivers of costs for orthopedic surgery in RA. Better medical and surgical treatments in recent…
Abstract Number: 75 • 2012 ACR/ARHP Annual Meeting
Patient-Reported Outcomes Associated with Achieving and Maintaining Low Disease Activity in Rheumatoid Arthritis
Martin J. Bergman¹, James W. Shaw², Mary Cifaldi³, Gourab De⁴, Tony He⁵, Rajeev Ayyagari⁵ and James Signorovitch⁵, ¹Taylor Hospital, Ridley Park, PA, ²Global Health Economics and Outcomes Research, Abbott Laboratories, Abbott Park, IL, ³Abbott Laboratories, Abbott Park, IL, ⁴Analysis Group, Inc., New York, NY, ⁵Analysis Group, Inc., Boston, MA
Background/Purpose: Treat-to-target (T2T) guidelines for rheumatoid arthritis (RA) recognize low disease activity (LDA) as an acceptable therapeutic goal, particularly in patients with longstanding disease. The…
Abstract Number: 76 • 2012 ACR/ARHP Annual Meeting
The Difference in Performance of DAS28 and RADAI During Pregnancy Might Explain Discrepancies Between Older and More Recent Studies On the Impact of Pregnancy On Rheumatoid Arthritis
Jan Naterop¹, Johanna M.W. Hazes² and Radboud J.E.M. Dolhain³, ¹Rheumatology, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands, Rotterdam, Netherlands, ²Rheumatology, Erasmus University Medical Center, Rotterdam, Netherlands, ³Rheumatology, Erasmus Medical Center, Rotterdam, Netherlands
Background/Purpose: Pregnancy is the only condition in which Rheumatoid Arthritis (RA) shows spontaneous remission. Both older and more recent studies showed improvement of disease activity,…
Abstract Number: 77 • 2012 ACR/ARHP Annual Meeting
Comorbid Conditions Do Not Explain Divergent Patient Assessments of Disease Activity and Global Health in Patients with Rheumatoid Arthritis
Dörte Huscher¹, Katja Thiele², Sascha Bischoff², Ulrich von Hinüber³, Guido Hoese⁴, Kirsten Karberg⁵, Wolfgang Ochs⁶ and Angela Zink⁷, ¹German Rheumatism Research Centre and Charité University Medicine, Berlin, Germany, ²German Rheumatism Research Centre, Berlin, Germany, ³Rheumatologist in Private Practice, Hildesheim, Germany, ⁴Rheumatologist in Private Practice, Stadthagen, Germany, ⁵Rheumatologist in Private Practice, Berlin, Germany, ⁶Rheumatologist in Private Practice, Bayreuth, Germany, ⁷Epidemiology Unit, German Rheumatism Research Centre and Charité University Medicine, Berlin, Germany
Background/Purpose: In the discussion of the 2010 ACR/EULAR remission criteria the issue has been raised to what extent patients are able to distinguish rheumatoid arthritis…
Abstract Number: 78 • 2012 ACR/ARHP Annual Meeting
Factors Influencing On the Discordance Between 2011 ACR/EULAR Criteria and Physician’s Clinical Judgment for Remission in Rheumatoid Arthritis Patients
Yoon-Kyoung Sung¹, Bo Young Yoon², Soo-Kyung Cho¹, Chan-Bum Choi¹, Dae-Hyun Yoo³, Jae-Bum Jun³, Tae-Hwan Kim³, Shin-Seok Lee⁴, Tae-Jong Kim⁵, Jisoo Lee⁶, Jung-Yoon Choe⁷, Sung-Hoon Park⁸, Seung-Jae Hong⁹, Yeon-Ah Lee⁹, Jinseok Kim¹⁰, Eun-Mi Koh¹¹, Hoon-Suk Cha¹¹, Jaejoon Lee¹¹, Won-Tae Chung¹², Sung Won Lee¹², Choong-Ki Lee¹³, Hye-Soon Lee¹⁴, Wan-Hee Yoo¹⁵, Young Mo Kang¹⁶ and Sang-Cheol Bae³, ¹Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ²Inje University Ilsan Paik Hospital, Goyang, South Korea, ³Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, ⁴Dept of Int Med/Rheumatology, Chonnam National University Medical School, Gwangju, South Korea, ⁵Rheumatology, Chonnam National University Medical School, Gwangju, South Korea, ⁶Internal Medicine, Ewha Womans University Mokdong Hospital, Seoul, South Korea, ⁷Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, South Korea, ⁸Catholic University of Daegu School of Medicine, Daegu, South Korea, ⁹Division of Rheumatology, Department of Internal Medicine, Kyung Hee University, Seoul, South Korea, ¹⁰Division of Rheumatology, Internal Medicine, Jeju National University Hospital, Jeju, Korea, South Korea, ¹¹Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, ¹²Rheumatology, Dong-A University Hospital, Busan, South Korea, ¹³Yeungnam University Hospital, Daegu, South Korea, ¹⁴Department of Rheumatology, Hanyang University Guri Hospital, Guri, South Korea, ¹⁵Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine, Jeonju, South Korea, ¹⁶Department of Internal Medicine (Rheumatology), Kyungpook National University School of Medicine, Daegu, South Korea
Background/Purpose: Remission is a primary end point in the treatment of rheumatoid arthritis (RA). To ensure more uniform reporting of outcome measures, American College of…
Abstract Number: 79 • 2012 ACR/ARHP Annual Meeting
Physician’s Global Assessment Is Affected by Physician’s Age and Gender, but Not by Patient Age and Gender in Rheumatoid Arthritis Patients Treated in Routine Care. Data From the Danish Nationwide Danbio Registry
Cecilie Lindstrom Egholm¹, Theodore Pincus², Lene Dreyer³, Torkell Ellingsen⁴, Bente Glintborg³, Marcin Kowalski⁵, Tove Lorenzen⁴, Ole Rintek Madsen⁶, Henrik Nordin⁷, Claus Rasmussen⁸ and Merete L. Hetland⁹, ¹Copenhagen University Hospital / DANBIO at Glostrup, Copenhagen, Denmark, ²Rheumatology, Rush University Medical Center, Chicago, IL, ³Copenhagen University Hospital at Gentofte, Gentofte, Denmark, ⁴Diagnostic Centre, Region Hospital Silkeborg, Silkeborg, Denmark, ⁵Aalborg University Hospital, Aalborg, Denmark, ⁶Dept. of Rheumatoglogy/C, Copenhagen University Hospital Gentofte, Hellerup, Denmark, ⁷Rigshospitalet, Copenhagen, Denmark, ⁸Vendsyssel Teaching Hospital/Aalborg University, Hjoerring, Denmark, ⁹Copenhagen University Hospital Glostrup, Copenhagen, Denmark
Background/Purpose: Several studies have shown that significant discordance exists between patient (PATGL) and physician (DOCGL) global measures of rheumatoid arthritis (RA) disease activity. These studies…
Abstract Number: 80 • 2012 ACR/ARHP Annual Meeting
Validation of Remission of Rheumatoid Arthritis by Traditional Disease Activity Score and Provisional Criteria by American College of Rheumatology and European League Against Rheumatism: Patient Reported Outcomes Analyzed From 3 Phase III Golimumab Trials
Chenglong Han¹, Edward Keystone², Roy Fleischmann³, Josef S. Smolen⁴, Paul Emery⁵, Mark C. Genovese⁶, Mittie K. Doyle⁷ and Elizabeth C. Hsia⁷, ¹Outcomes Research, Johnson & Johnson Pharmaceutical Services, LLC, Malvern, PA, ²Rebecca MacDonald Centre for Arthritis and Autoimmune Disease, University of Toronto, Toronto, ON, Canada, ³Southwestern Medical Center at Dallas, University of Texas, Dallas, TX, ⁴Division of Rheumatology, Department of Internal Medicine III,, Medical University of Vienna and Hietzing Hospital, Vienna, Austria, ⁵Medicine, Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, ⁶Division of Rheumatology, Stanford University, Palo Alto, CA, ⁷Janssen Research and Development, LLC, Spring House, PA
Background/Purpose: Remission by Boolean-based definition (all scores on the tender joint and swollen joint count, CRP (mg/dL), and patient global assessment ≤1) and by Simplified…
Abstract Number: 81 • 2012 ACR/ARHP Annual Meeting
Transitions Among Disease Activity States: Estimates and Models of Covariate Associations
George W. Reed¹, David H. Collier², Andrew S. Koenig³, Katherine C. Saunders⁴, Joel M. Kremer⁵ and Sameer Kotak⁶, ¹University of Massachusetts Medical School, Worcester, MA, ²Amgen Inc., Thousand Oaks, CA, ³Specialty Care, Pfizer Inc, Collegeville, PA, ⁴Corrona, LLC., Southborough, MA, ⁵Albany Medical College and The Center for Rheumatology, Albany, NY, ⁶Specialty Care, Pfizer Inc., New York, NY
Background/Purpose: Many RA patients have variable disease activity over time due to disease variability, reduction in efficacy of current medications, environmental factors and other…
Abstract Number: 82 • 2012 ACR/ARHP Annual Meeting
Variability of the SF-6D Determinants Over Time in Early Arthritis:Results From the Espoir Cohort
Cécile Gaujoux-Viala¹, Bruno Fautrel², Kossar Hosseini³, Francis Guillemin³, René-Marc Flipo⁴ and Anne-Christine Rat⁵, ¹Lorraine University, Paris Descartes University, APEMAC, EA 4360, F- 54 000, Nancy; Paris 6 – Pierre et Marie Curie University; Rheumatology, Pitié-Salpêtrière Hospital, Paris, France, ²APHP, Pitié-Salpêtrière University Hospital, Paris, France, ³Lorraine University, Paris Descartes University, APEMAC, EA 4360, F- 54 000, Nancy, France, ⁴Rheumatology Department, Lille University Hospital, Lille, France, ⁵CHU Nancy, Clinical Epidemiology and Evaluation, Université de Lorraine, Paris Descartes University, APEMAC, EA 4360, Nancy, France
Background/Purpose: There is growing emphasis on the cost-effectiveness of treating rheumatoid arthritis. The SF-6D, derived from the SF36, is an indirect utility measure widely used…
Abstract Number: 83 • 2012 ACR/ARHP Annual Meeting
Substantial Functional Disability Is the Key Determinant of Discrepancies Between EQ-5D and SF-6D Utility Measures in Early Arthritis: Results From the Espoir Cohort
Cécile Gaujoux-Viala¹, Bruno Fautrel², Kossar Hosseini³, Francis Guillemin⁴, René-Marc Flipo⁵ and Anne-Christine Rat³, ¹Rheumatology, Montpellier I University, Nîmes University Hospital, Nîmes, France, ²Rheumatology, UPMC - Paris 6 University, Paris, France, ³CHU Nancy, Clinical Epidemiology and Evaluation, Université de Lorraine, Paris Descartes University, APEMAC, EA 4360, Nancy, France, ⁴Université de Lorraine, Paris Descartes University, APEMAC, EA 4360, F- 54 000, Nancy, France, ⁵Rheumatology Department, Lille University Hospital, Lille, France
Background/Purpose: The EQ-5D, a 5-dimensional multi-attribute questionnaire, and the SF-6D, derived from the SF36, are 2 indirect utility measures widely used to calculate quality-adjusted life-years…
Abstract Number: 84 • 2012 ACR/ARHP Annual Meeting
Benefits of Treat-to-Target Guideline Compliance in Patients with Rheumatoid Arthritis: A Retrospective Claims Analysis
Martin J. Bergman¹, James W. Shaw², Mary A. Cifaldi³, Annie Guerin⁴, Pooja Chopra⁵ and James Signorovitch⁵, ¹Taylor Hospital, Ridley Park, PA, ²Global Health Economics and Outcomes Research, Abbott Laboratories, Abbott Park, IL, ³Abbott Laboratories, Abbott Park, IL, ⁴Analysis Group, Inc., Montreal, QC, Canada, ⁵Analysis Group, Inc., Boston, MA
Background/Purpose: To achieve clinical remission/low disease activity in patients with rheumatoid arthritis (RA), the treat-to-target (T2T) guidelines recommend frequent disease monitoring through patient-rheumatologist interactions. The…
Abstract Number: 86 • 2012 ACR/ARHP Annual Meeting
Longitudinal Hypertension Diagnosis and Control Among a Primary Care Medically Homed Population with Rheumatoid Arthritis
Katya Voelker¹ and Christie M. Bartels², ¹Univ of Wisconsin School of Medicine and Public Health, Madison, AA, ²Rheumatology/Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI
Longitudinal Hypertension Diagnosis and Control among a Primary Care Medically Homed Population with Rheumatoid ArthritisBackground/Purpose: Hypertension is a key risk factor for cardiovascular disease (CVD)…
Abstract Number: 46 • 2012 ACR/ARHP Annual Meeting
Synovitis in Secondary Osteoarthritis Due to Rheumatoid Arthritis: A Proof-of-Concept Study
Stefan Vordenbäumen¹, Tim Lögters², Philipp Sewerin¹, Thomas Pauly³, Ellen Bleck⁴, Paulina Philippski¹, Matthias Schneider¹, Michael Schädel-Höpfner² and Benedikt Ostendorf¹, ¹Endocrinology, Diabetology and Rheumatology, Heinrich-Heine-University, Düsseldorf, Germany, ²Trauma and Hand Surgery, Heinrich-Heine-University, Düsseldorf, Germany, ³Orthopaedics, Rheinisches Rheumazentrum St. Elisabeth-Hospital, Meerbusch, Germany, ⁴Rheumatology, Heinrich-Heine-University, Düsseldorf, Germany
Background/Purpose: Rheumatoid arthritis (RA) is characterized by considerable synovial inflammation which may result in secondary osteoarthritis (sOA). Primary OA (pOA) occurs in patients without predisposing…
Abstract Number: 47 • 2012 ACR/ARHP Annual Meeting
Accumulation of CD34+ Hematopoietic Stem Cells in the Initial Inflammatory Human Fracture Hematoma Is Mediated Via Chemokine Receptor Type 3 Ligands
Paula Hoff¹, Timo Gaber¹, Martin Hahne¹, Cindy Strehl¹, Katharina Schmidt-Bleek², Gerd Burmester³, Gerhard Schmidmaier⁴, Georg Duda⁵, Carsten Perka⁶ and Frank Buttgereit⁷, ¹Department of Rheumatology and Clinical Immunology, Charité University Medicine, Berlin, Germany, ²Julius Wolff Institut, Charité University Medicine, Berlin, Germany, ³Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany, ⁴Department of Traumatology, Heidelberg University Hospital, Heidelberg, Germany, ⁵Julius Wolff Institute, Charité – Universitätsmedizin Berlin, Berlin, Germany, ⁶Center of Muscoloskeletal Surgery, Charité University Medicine, Berlin, Germany, ⁷Charité - Universitätsmedizin Berlin, Berlin, Germany
Background/Purpose: We have previously shown the early phase of human fracture healing to be characterized by hypoxia which promotes inflammation and chemoattraction. Hypoxia is also…
Abstract Number: 48 • 2012 ACR/ARHP Annual Meeting
Tissue Engineering for Articular Cartilage Repair, Culturing Bone Marrow Mesenchymal Stem Cells On Collagen and Heparan Sulphate Scaffolds
Adela Helvia Martinez-Sanchez¹, Clara Sanjurjo-Rodriguez¹, Silvia Diaz-Prado², Emma Muiños¹, Isaac M. Fuentes², Francisco J. De Toro², Julia Bujan³ and Francisco J. Blanco¹, ¹Osteoarticular and Aging Res. Lab. CIBER-BBN. Rheumatology Div. INIBIC-Complejo Hosp. Univ. A Coruña, A Coruña, Spain, ²Osteoarticular and Aging Res. Lab. CIBER-BBN. INIBIC-University of A Coruña, A Coruña, Spain, ³Department of Medical Specialties. University of Alcala de Henares, Madrid, Spain
Background/Purpose: The aim of this study was to evaluate the chondrogenic potential of bone marrow mesenchymal stem cells (BM-MSCs) grown on type I collagen and…

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