Abstracts Archive - Page 2594 of 2607 - ACR Meeting Abstracts

Abstract Number: 135 • 2012 ACR/ARHP Annual Meeting
A Pilot Study of the Efficacy of IL1 Blockade by Anakinra in Acute Calcific Periarthritis of the Rotator Cuff
Pascal Zufferey¹, Melanie Faucherre², Pierre A. Varisco¹, Berengere Aubry Sr.¹, Isabelle Fabreguet³ and Alexander K. So Sr.¹, ¹Dal/Rhu, CHUV, Lausanne, Switzerland, ²Dal /Rhu, CHUV, Lausanne, Switzerland, ³CHUV, Lausanne, Switzerland
Background/Purpose: Calcific periarthritis of rotator cuff can induce acute and severe shoulder pain and is accompnied by signs of acute inflammation. The calcific deposits are…
Abstract Number: 136 • 2012 ACR/ARHP Annual Meeting
A Delphi Exercise to Identify Characteristic Features of Gout – A Study of Opinions From Patients and Physicians to Inform New Classification Criteria
Rebecca Prowse¹, Nicola Dalbeth², H. R. Schumacher³, Tuhina Neogi⁴, Tim L. Jansen⁵, Jaap Fransen⁶ and William Taylor¹, ¹University of Otago, Wellington, New Zealand, ²Medicine, University of Auckland, Auckland, New Zealand, ³Rheumatology, University of Pennsylvania and VA Medical Center, Philadelphia, PA, ⁴Boston University School of Medicine, Boston, MA, ⁵Rheumatology, St Radboud University Nijmegen Medical Centre, Netherlands, ⁶Rheumatic Diseases, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
A Delphi Exercise to Identify Characteristic Features of Gout - a Study of Opinions from Patients and Physicians to Inform New Classification CriteriaBackground/Purpose: Updated classification…
Abstract Number: 137 • 2012 ACR/ARHP Annual Meeting
Monosodium Urate Crystals Inhibit Tenocyte Viability and Function: Implications for Periarticular Involvement in Chronic Gout
Ashika Chhana¹, Karen E. Callon¹, Bregina Pool¹, Dorit Naot¹, Gregory Gamble², Brendan Coleman³, Fiona M. McQueen⁴, Jillian Cornish¹ and Nicola Dalbeth¹, ¹Medicine, University of Auckland, Auckland, New Zealand, ²Department of Medicine, University of Auckland, Auckland, New Zealand, ³Orthopedic Surgery, Middlemore Hospital, Auckland, New Zealand, ⁴Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand
Background/Purpose: Recent advanced imaging studies have demonstrated that urate deposition in periarticular structures is common in gout. Urate deposition has been observed both adjacent to…
Abstract Number: 138 • 2012 ACR/ARHP Annual Meeting
Evaluating Appropriate Use of Prophylactic Colchicine and Urate Lowering Therapy in Gout
Michael George¹, Sally W. Pullman-Mooar² and H. Ralph Schumacher³, ¹Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, ²Rheumatology, University of Pennsylvania and Philadelphia Veterans Hospital, Philadelphia, PA, ³Department of Medicine, University of Pennsylvania and VA Medical Center, Philadelphia, PA
Background/Purpose: Colchicine is recommended to prevent gout flares in patients initiating and increasing uric acid lowering therapy until serum uric acid is ≤ 6 mg/dL.…
Abstract Number: 139 • 2012 ACR/ARHP Annual Meeting
Lack of Effect of Supplemental Vitamin C On Serum Urate in Patients with Gout
Lisa K. Stamp¹, Christopher Frampton¹, John L. O'Donnell², Jill Drake³ and Peter T. Chapman⁴, ¹Department of Medicine, University of Otago, Christchurch, Christchurch, New Zealand, ²Rheumatology Immunology & Allergy, Canterbury Health Laboratories, Christchurch, New Zealand, ³Rheumatology, Immunology and Allergy, Christchurch Hospital, Christchurch, New Zealand, ⁴Rheumatology, Immunology & Allergy, Christchurch Hospital, Christchurch, New Zealand
Background/Purpose: The key to effective long-term management of gout is sustained reduction of serum urate (SU) Methods: Patients with gout and a SU >0.36mmol/L…
Abstract Number: 140 • 2012 ACR/ARHP Annual Meeting
Patients That Continue to Flare Despite Apparent Optimal Urate Lowering Therapy
Dinesh Khanna¹, Puja Khanna², David Hagerty³, Chris Storgard⁴, Robert Mischler⁵ and Robert Morlock⁵, ¹Division of Rheumatology, University of Michigan Medical Center, Ann Arbor, MI, ²Division of Rheumatology/Dept. of Internal Medicine, University of Michigan Medical Center, Ann Arbor, MI, ³Medical, Ardea Bioscience, San Diego, CA, ⁴4939 Directors Place, Ardea Bioscience, San Diego, CA, ⁵Ardea Bioscience, San Diego, CA
Background/Purpose: Gout is a common inflammatory arthritis and its worldwide prevalence is increasing. The purpose of this study is to describe physician, patient and treatment…
Abstract Number: 141 • 2012 ACR/ARHP Annual Meeting
Effectiveness of Prophylaxis with Anti-Gout Medications On Risk of Gout Attacks
Tuhina Neogi¹, Clara Chen², Jingbo Niu³, Christine E. Chaisson⁴, David J. Hunter⁵, Hyon Choi⁶ and Yuqing Zhang⁷, ¹Clinical Epidemiology, Boston University School of Medicine, Boston, MA, ²Boston University School of Public Health, Boston, MA, ³Boston University School of Medicine, Boston, MA, ⁴Arthritis Center, Boston University School of Public Health, Boston, MA, ⁵Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, ⁶Section of Rheumatology and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ⁷Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA
Background/Purpose: While a few studies have examined colchicine's ability to prevent gout attacks, NSAIDs have not been formally studied in this regard, despite use of…
Abstract Number: 142 • 2012 ACR/ARHP Annual Meeting
Efficacy of Canakinumab Versus Triamcinolone Acetonide According to Multiple Gouty Arthritis-Related Health Outcomes Measures
Ari Gnanasakthy¹, Andrew Sarkin², Rachel Lale², Kyle Choi² and Jan D. Hirsch³, ¹Novartis Pharmaceuticals Corporation, East Hanover, NJ, ²Health Services Research Center, University of California, San Diego, CA, ³Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California, San Diego, CA
Background/Purpose: Canakinumab (CAN), a selective, fully human, anti-IL-1β monoclonal antibody, may be a potential therapeutic option for treating acute gout attacks and delaying new attacks…
Abstract Number: 143 • 2012 ACR/ARHP Annual Meeting
Proposed Gout Treatment Guidelines and Meeting Serum Urate and Flare Goals
Jasvinder A. Singh¹, David Hagerty², Chris Storgard³, Robert Mischler⁴ and Robert Morlock⁴, ¹Department of Medicine, University of Alabama, Tuscaloosa, AL, ²Medical, Ardea Bioscience, San Diego, CA, ³4939 Directors Place, Ardea Bioscience, San Diego, CA, ⁴Ardea Bioscience, San Diego, CA
Background/Purpose: Although gout is a relatively common condition, treatment is often not ideal with many patients continuing to experience multiple flares and some developing complications…
Abstract Number: 144 • 2012 ACR/ARHP Annual Meeting
Long-Term Safety of Canakinumab in Patients with Gouty Arthritis
Alexander So¹, Reike Alten², H. Ralph Schumacher³, Mark Bloch⁴, Thomas Bardin⁵, Markus R. John⁶, Gerhard Krammer⁶, Jan Michael Nebesky⁶, Aiyang Tao⁷ and Naomi Schlesinger⁸, ¹Rheumatology, CHUV, Univ of Lausanne, Lausanne, Switzerland, ²Charité Univ Medicine, Berlin, Germany, ³Department of Medicine, University of Pennsylvania and VA Medical Center, Philadelphia, PA, ⁴Holdsworth House Medical Practice, Sydney, Australia, ⁵Rheumatology, Hôpital Lariboisière, Paris, France, ⁶Novartis Pharma AG, Basel, Switzerland, ⁷Novartis Pharmaceuticals Corporation, East Hanover, NJ, ⁸UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ
Background/Purpose: Gouty arthritis (GA) is a chronic inflammatory disease. Targeting the inflammatory pathway through IL-1β inhibition with canakinumab (CAN) may provide significant long-term benefits. CAN…
Abstract Number: 145 • 2012 ACR/ARHP Annual Meeting
Prevalence of Non-Gout Arthritis in Patients with Gout: Not As Sparing As Previously Thought
Fernando Perez-Ruiz¹ and Ana M. Herrero-Beites², ¹Servicio de Reumatologia, Hospital Universitario Cruces, Baracaldo, Spain, ²Physical Medicine Division, Hospital de Gorliz, Gorliz, Spain
Background/Purpose: the presence of other chronic inflammatory disease has been historically and academically thought to be “protective” conditions for the development of gout. Objective: to…
Abstract Number: 146 • 2012 ACR/ARHP Annual Meeting
The Treatment of Acute Gouty Arthritis in Complex Hospitalized Patients with Anakinra
Mary Bach¹, Jane Park¹, Pradipta Ghosh¹, Peter A. Simkin² and Gregory C. Gardner³, ¹Rheumatology, University of Washington, Seattle, WA, ²Div of Rheumatology, University of Washington, Seattle, WA, ³Medicine/Rheumatology, University of Washington, Seattle, WA
Background/Purpose: The management of acute crystal-induced arthritis in the hospital setting may be a difficult clinical problem due to co-morbidities that limit the use of…
Abstract Number: 107 • 2012 ACR/ARHP Annual Meeting
Sensitivity to Change of the Ultrasound synovitis SONAR Score in RA Patients : Results of the Scqm Cohort
Pascal Zufferey¹, Almut Scherer², Hans Rudolf Ziswiler³, Giorgio Tamborrini⁴, Laure Brulhart⁵ and Burkhard Moeller⁶, ¹Service of Rheumatology, Department of Musculoskeletal Medicine, Lausanne University Hospital, Lausanne, Switzerland, ²SCQM Foundation, Zurich, Switzerland, ³Rheumatology, Clinical Immunology and Allergology, Inselspital, University of Bern, Bern, Switzerland, ⁴Department of Rheumatology, University Hospital, Zurich, Switzerland, ⁵service de Rhumatologie, Geneva, Switzerland, ⁶Rheumatology & Clin Immunology, Inselspital Bern, Bern, Switzerland
Background/Purpose: Since the end of 2009, an ultrasound scoring call SONAR has been implemented for RA patients as a routine tool in the SCQM registry…
Abstract Number: 108 • 2012 ACR/ARHP Annual Meeting
Disparity Between Sonographic and Clinical Criteria of Remission in Psoriasis Arthritis
Christian Dejaco¹, Rusmir Husic², Judith Gretler³, Winfried B. Graninger⁴ and Josef Hermann², ¹Rheumatology, Southend University Hospital, Westcliff-on-Sea, United Kingdom, ²Rheumatology, Medical University Graz, Graz, Austria, ³Med Univ Klinik Graz, Auenbruggerplatz 15, Graz, Austria, ⁴Internal medicine/Rheumatology and Immunology, Medical University Graz, Graz, Austria
Background/Purpose: To compare ultrasound and clinical definitions of remission in psoriasis arthritis (PsA). Methods: Prospective study of 70 consecutive PsA patients [mean age 51.1 (±SD…
Abstract Number: 109 • 2012 ACR/ARHP Annual Meeting
Does Joint Sonography Really Add Clinically Important Information Beyond Clinical Joint Examination?
Miriam Gärtner¹, Helga Radner², Gabriela Supp², Peter Mandl³, Daniel Aletaha¹, Klaus P. Machold⁴ and Josef S. Smolen⁵, ¹Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ²Department of Internal Medicine III; Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ³Rheumatology, Medical University of Vienna, Vienna, Austria, ⁴Internal Medicine III, Medical University of Vienna, Vienna, Austria, ⁵Division of Rheumatology, Department of Internal Medicine III,, Medical University of Vienna and Hietzing Hospital, Vienna, Austria
Background/Purpose: Sonographic assessment of joint activity in patients with rheumatoid arthritis (RA) is considered to be more sensitive than the respective clinical assessment. However, this…

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