Abstracts Archive - Page 2566 of 2607 - ACR Meeting Abstracts

Abstract Number: 559 • 2012 ACR/ARHP Annual Meeting
Utility of Dual-Energy X-Ray absorptiometry Scanning and Risk of Osteoporosis in Ankylosing Spondylitis; A Prospective Study
Marina N. Magrey¹ and Muhammad Asim Khan², ¹Case Western Reserve University School of Medicine at MetroHealth Medical Center, Cleveland, OH, ²Medicine/ Rheumatology, CASE at MetroHealth Med Center, Cleveland, OH
Background/Purpose: Conventional DXA imaging of spine and hip to measure bone mineral density (BMD) has limitations in patients with ankylosying spondylitis (AS) as their spinal…
Abstract Number: 560 • 2012 ACR/ARHP Annual Meeting
Proteomic Profiling of Synovial Fluid Reveals Candidate Psoriatic Arthritis Biomarkers
Daniela Cretu¹, Ihor Batruch², Punit Saraon³, Dafna D. Gladman⁴, Fawnda Pellett⁵, Eleftherios Diamandis⁶ and Vinod Chandran⁷, ¹Department of Laboratory Medicine and Pathobiology, University of Toronto, Department of Laboratory Medicine and Pathobiology, Toronto, ON, Canada, ²Department of Pathology and Lab Medicine,, Mount Sinai Hospital, Toronto, ON, Canada, ³Department of Pathology and Lab Medicine, Mount Sinai Hospital, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada, ⁴Division of Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ⁵Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁶Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada, ⁷Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada
Background/Purpose: Psoriatic arthritis (PsA) is a unique form of arthritis occurring in 30% of psoriasis patients. There is a high prevalence of undiagnosed PsA in…
Abstract Number: 561 • 2012 ACR/ARHP Annual Meeting
Performance of Magnetic Resonance Imaging in Detection of Chronic Structural Changes in Sacroiliac Joints As Compared to Conventional X-Rays in Axial Spondyloarthritis
Denis Poddubnyy¹, Inna Gaydukova², Hildrun Haibel¹, In-Ho Song¹ and Joachim Sieper¹, ¹Medical Department I, Rheumatology, Charité Medical University, Campus Benjamin Franklin, Berlin, Germany, ²Hospital Therapy, Saratov State Medical University, Saratov, Russia
Background/Purpose: Conventional x-rays of the sacroiliac joints (SIJ) remains the first imaging method in case of suspicion of axial spondyloarthritis (SpA). Moreover, a diagnosis of…
Abstract Number: 562 • 2012 ACR/ARHP Annual Meeting
Prevalence and Predictors of Significant Liver Fibrosis in Methotrexate Treated Rheumatoid and Psoriatic Arthritis Patients Using Transient Elastography (fibroscan)
WC Chan¹, ML Yip² and CK Loo¹, ¹Division of Gastroenterology and Hepatology, Department of Medicine, Kwong Wah Hospital, Kowloon, Hong Kong, ²Division of Rheumatology, Department of Medicine, Kwong Wah Hospital, Kowloon, Hong Kong
Background/Purpose: Methotrexate ( MTX ) is an anchor drug in the treatment of Rheumatoid ( RA ) and Psoriatic arthritis ( PSA )and is the…
Abstract Number: 563 • 2012 ACR/ARHP Annual Meeting
In Ankylosing Spondylitis, a Decrease in MRI Spinal Inflammation Predicts Improvement in Spinal Mobility Independently of Patient Reported Symptomatic Improvement
Pedro Machado¹, Robert Landewé², Jürgen Braun³, Xenofon Baraliakos⁴, Kay-Geert A. Hermann⁵, Benjamin Hsu⁶, Daniel Baker⁷ and Désirée van der Heijde¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam and Atrium Medical Center, Heerlen, Netherlands, ³PsAID taskforce, EULAR, Zurich, Switzerland, ⁴Rheumatology, Rheumazentrum Ruhrgebiet, Herne, Germany, ⁵Radiology, Charité Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany, ⁶Janssen Research & Development, LLC., Spring House, PA, ⁷Research and Development, Centocor Inc., Malvern/Philadelphia, PA
Background/Purpose: It has been previously shown that spinal mobility in ankylosing spondylitis (AS) is associated with the level of inflammation of the spine. However an…
Abstract Number: 564 • 2012 ACR/ARHP Annual Meeting
Almost 40% of Patients with Chronic Back Pain Starting Before the Age of 45 Fulfill the ASAS Axial Spondyloarthritis Criteria
Manouk de Hooge¹, Rosaline van den Berg¹, Floris van Gaalen¹, Monique Reijnierse², Tom Huizinga¹ and Désirée van der Heijde¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Radiology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Chronic back pain is a very prevalent complaint in the general population but only a small proportion of these patients suffer from spondyloarthritis (SpA).…
Abstract Number: 565 • 2012 ACR/ARHP Annual Meeting
Fetuin A: A New Biomarker Related with Syndesmophytes in Patients with Ankylosing Spondylitis
Tugba Tuylu¹, Dilek Solmaz², Ismail Sari², Didem L. Kozaci³, Servet Akar⁴, Necati Gunay³ and Nurullah Akkoc⁵, ¹Internal Medicine, Dokuz Eylul University School of Medicine, Izmir, Turkey, ²Rheumatology, Dokuz Eylul University School of Medicine, Izmir, Turkey, ³Biochemistry, Adnan Menderes University School of Medicine, Aydin, Turkey, ⁴Rheumatology, Dokuz Eylul University School of Medicine Department of Internal Medicine Division of Rheumatology, Izmir, Turkey, ⁵Rheumatology, Dokuz Eylul University School Of Medicine, Department Of Internal Medicine, Division Of Rheumatology, Izmir, Turkey
Background/Purpose: In recent years, there is considerable interest regarding prediction and pathogenesis of syndesmophyte formation. Thus, several studies were conducted in order to identify the…
Abstract Number: 566 • 2012 ACR/ARHP Annual Meeting
Effect of TNF Antagonists On Radiographic Progression in Psoriatic Arthritis: Systematic Review and Meta-Analysis of Randomized Controlled Trials
Radjiv Goulabchand¹, Gael Mouterde¹, Cédric Lukas², Thomas Barnetche³, Jacques Morel¹ and Bernard Combe¹, ¹Rheumatology, Montpellier 1 University, Lapeyronie Hospital, Montpellier, France, ²Immuno-Rhumatologie, Hopital Lapeyronie, Montpellier, France, ³Rheumatology, CHU Bordeaux Pellegrin, Bordeaux, France
Background/Purpose: Psoriatic arthritis (PsA) can cause important structural damages which can lead to disability. TNF antagonists have shown their clinical efficacy in PsA, but only…
Abstract Number: 567 • 2012 ACR/ARHP Annual Meeting
Prevalence of Psoriasis and Psoriatic Arthritis in a Northern Population of Spain
Jose Luis Fernandez-Sueiro¹, JA Pinto¹, S. Pertega-Diaz², Manuel Acasuso³ and Ignacio Herrero de Padura⁴, ¹Rheumatology Division, Complejo Hospitalario Universitario La Coruña, La Coruña, Spain, ²Epidemiology and Statistics, Complejo Hospitalario Universitario La Coruña, La Coruña, Spain, ³Centro de Salud San José, Centro de Salud, San José, La Coruña, Spain, ⁴Centro de Salud San Jose, Centro de Salud, San José, La Coruña, Spain
Background/Purpose: There are few data in Spain evaluating the prevalence of psoriasis in the general population, accordingly there are not data evaluating the prevalence of…
Abstract Number: 568 • 2012 ACR/ARHP Annual Meeting
14-3-3 Eta Is a Modifiable Serum Biomarker That Marks Adalimumab Response in Psoriatic Arthritis
Anthony Marotta¹, A. W van Kuijk², Walter P. Maksymowych³ and Paul Peter Tak⁴, ¹Augurex Life Sciences Corp, North Vancouver, BC, Canada, ²Clinical Immunology / Rheumatology, Academic Medical Centre/University of Amsterdam, Amsterdam, Netherlands, ³Department of Medicine, University of Alberta, Edmonton, AB, Canada, ⁴Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands
Background/Purpose: 14-3-3 eta is a synovial-derived biomarker whose serum expression is independently associated with joint damage in RA and PsA. We previously reported that 14-3-3…
Abstract Number: 569 • 2012 ACR/ARHP Annual Meeting
Ustekinumab Improves Arthritis-Related and Skin-Related Quality of Life in Patients with Active Psoriatic Arthritis: Patient Reported Outcomes From Randomized and Double Blinded Phase III Psummit I Trial
Arthur Kavanaugh¹, Iain B. McInnes², Alice B. Gottlieb³, Lluis Puig⁴, Proton Rahman⁵, Christopher T. Ritchlin⁶, Shu Li⁷, Yuhua Wang⁷, Chenglong Han⁸, Alan Mendelsohn⁹ and Mittie K. Doyle⁷, ¹UCSD School of Medicine, La Jolla, CA, ²Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom, ³Tufts Medical Center, Boston, MA, ⁴Universitat Autònoma de Barcelona, ⁵Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, ⁶Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, ⁷Janssen Research & Development, LLC, Spring House, PA, ⁸Johnson & Johnson Pharmaceutical Services, LLC., Malvern, PA, ⁹Immunology, Janssen Research & Development, LLC, Spring House, PA
Ustekinumab Improves Arthritis-related and Skin-related Quality of Life in Patients with Active Psoriatic Arthritis: Patient Reported Outcomes from Randomized and Double Blinded Phase III PSUMMIT…
Abstract Number: 570 • 2012 ACR/ARHP Annual Meeting
Randomized Controlled Trial of Adalimumab in Patients with Peripheral Spondyloarthritis
Philip J. Mease¹, Joachim Sieper², Filip Van den Bosch³, Proton Rahman⁴, Katie Obermeyer⁵ and Aileen L. Pangan⁵, ¹Rheumatology Research, Swedish Medical Center, Seattle, WA, ²Medical Department I, Rheumatology, Charité Universitätesmedizin Berlin, Berlin, Germany, ³Rheumatology, Ghent University Hospital, Ghent, Belgium, ⁴Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, ⁵Abbott Laboratories, Abbott Park, IL
Background/Purpose: Adalimumab (ADA) is indicated for the treatment of psoriatic arthritis (PsA) and ankylosing spondylitis (AS). Patients (pts) with peripheral spondyloarthritis (SpA) not previously diagnosed…
Abstract Number: 530 • 2012 ACR/ARHP Annual Meeting
S100A8/A9 Is Upregulated and Triggers the Secretion of Pro-Inflammatory Cytokines in Primary Sjögren’s Syndrome
Laura Weichselbaum¹ and Muhammad S. Soyfoo², ¹Rheumatology, Department of rheumatology ,Hôpital Erasme, Brussels, Belgium, ²Rheumatology, Hôpital Erasme,Université Libre de Bruxelles, Brussels, Belgium
Background/Purpose: To determine the involvement of S100A8/A9 in the pathogenesis of primary Sjögren’s syndrome (pSS) Methods: The serum levels of S100A8/A9, IL-17A and IL-17C were…
Abstract Number: 531 • 2012 ACR/ARHP Annual Meeting
Developmen and Validation of a New Instrument to Asess Health Related Quality of Life in Psoriasis Arthritis: The Vitacora Questionnaire
Juan Carlos Torre-Alonso¹, J. Santos-Rey², JM Ruiz-Martin³, P. Valdazo-De Diego⁴, Mireia Moreno⁵ and Juan-Antonio Fernández⁶, ¹Unit Rheumatology, Hospital Monte Naranco, Oviedo, Spain, ²Rheumatology, Toledo, Spain, ³Rheumatology, Viladecans, Spain, ⁴Rheumatology, Zamora, Spain, ⁵Rheumatology, Corporació Sanitària Parc Taulí, Sabadell, Spain, ⁶MP, Oviedo, Spain
Background/Purpose: To develop and validate a specific questionnaire to measure health-related quality of life (HRQoL) in adults with psoriasis arthritis (PA) for use in clinical…
Abstract Number: 532 • 2012 ACR/ARHP Annual Meeting
The Prevalance of Autoimmune Thyroid Disfunction in Ankylosing Spondylitis
Hakan Emmungil¹, Mehmet Erdogan², Melike Kalfa¹, Gonca Karabulut¹, Hayriye Kocanaogullari¹, Vedat Inal¹, Yasemin Kabasakal³, Fahrettin Oksel⁴, Kenan Aksu⁵ and Gokhan Keser⁶, ¹Dept. of Internal Medicine, Division of Rheumatology, Ege University, Dept. of Internal Medicine, Division of Rheumatology, Ege University, Izmir, Turkey, ²Dept. of Internal Medicine, Division of Endocrinolgy, Ege University, Dept. of Internal Medicine, Division of Endocrinolgy, Ege University, Izmir, Turkey, ³Dept. of Internal Medicine, Division of Rheumatology, Ege University, Izmir, Turkey, ⁴Division of Rheumatology, Ege University, Izmir, Turkey, ⁵Dept. Of Internal Medicine, Division of Rheumatology, Ege University, Dept. Of Internal Medicine, Division of Rheumatology, Ege University, Izmir, Turkey, ⁶Dept. of Internal Medicine, Division of Rheumatology, Dept. of Internal Medicine, Division of Rheumatology, Ege University, Izmir, Turkey
Background/Purpose: Although the association of autoimmune thyroid dysfunction and primary Sjögren's syndrome (SjS) is well known, it is less clear whether a similar relationship also…

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