Abstracts Archive - Page 2542 of 2607 - ACR Meeting Abstracts

Abstract Number: 922 • 2012 ACR/ARHP Annual Meeting
Risk of Fracture Among Treated and Untreated Men with Osteoporosis
Karen Tomic¹, Joanne Lafleur², Liisa Palmer¹, David M. Smith¹, Carly J. Paoli³, Irene Agodoa³ and Nicole Yurgin³, ¹Truven Health Analytics, Washington, DC, ²University of Utah College of Pharmacy, Salt Lake City, UT, ³Amgen Inc, Thousand Oaks, CA
Background/Purpose: Osteoporosis (OP) affects an estimated 2 million men in the United States. The relationship between treatment and fracture outcomes has been reported from clinical…
Abstract Number: 923 • 2012 ACR/ARHP Annual Meeting
Low Bone Mineral Density and Higher Parathyroid Hormone Levels As Independent Factors to All-Cause Mortality in Community-Dwelling Older Adults: the São Paulo Ageing & Health Study (SPAH)
Diogo S. Domiciano¹, Luana G. Machado², Jaqueline B. Lopes², Camille P. Figueiredo², Valéria Caparbo³, Liliam Takayama², Eloisa Bonfa⁴ and Rosa M.R. Pereira³, ¹Rheumatology, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil, ²Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ³Rheumatology, University of São Paulo, São Paulo, Brazil, ⁴Rheumatology Division, University of São Paulo, Sao Paulo, Brazil
Background/Purpose: Previous studies have shown a relationship between osteoporosis and increased risk of death. Moreover, secondary hyperparathyroidism has been linked to mortality amongst frail older…
Abstract Number: 924 • 2012 ACR/ARHP Annual Meeting
Methods to Link a U.S. Arthritis Cohort with Medicare Administrative Claims Data
Jeffrey R. Curtis¹, Lang Chen², Timothy Beukelman³, Aseem Bharat⁴, Fenglong Xie⁵, Kenneth G. Saag⁶ and Elizabeth S. Delzell⁷, ¹Rheumatology & Immunology, Univ of Alabama-Birmingham, Birmingham, AL, ²Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ³Pediatric Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁴Medicine/Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁵Rheumatology & Immunology, University of Alabama at Birmingham, Birmingham, AL, ⁶Div Clinical Immun & Rheum, Univ of Alabama-Birmingham, Birmingham, AL, ⁷Epidemiology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Linkages between clinical and administrative data may provide a valuable resource for pharmacoepidemiologic and health services research. Objective To describe methods and validity of…
Abstract Number: 925 • 2012 ACR/ARHP Annual Meeting
Use of Rheumatology Services for Arthritis: The Role of SES and Geographic Availability of Rheumatologists and Primary Care Physicians
E. M. Badley¹, Mayilee Canizares² and Aileen M. Davis³, ¹Division of Health Care and Outcomes Research,Toronto Western Research Institute; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada, ²Division of Health Care and Outcomes Research,Toronto Western Research Institute, Toronto, ON, Toronto, ON, Canada, ³Division of Health Care and Outcomes Research, Toronto Western Research Institute, Departments of Rehabilitation Science and Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada
Background/Purpose: Access to rheumatology is critical for timely treatment of new onset inflammatory arthritis (IA). Barriers to timely care include patient characteristics, the need for…
Abstract Number: 926 • 2012 ACR/ARHP Annual Meeting
Accuracy of Canadian Health Administrative Databases in Identifying Patients with Rheumatoid Arthritis Using a Random Sample of 7500 Patients Seen in Primary Care
Jessica Widdifield¹, Claire Bombardier², Sasha Bernatsky³, J. Michael Paterson⁴, Jacqueline Young⁴, Diane Green⁴, J. Carter Thorne⁵, Noah Ivers¹, Debra Butt⁴, R. Liisa Jaakkimainen⁶, Myra Wang⁴, Vandana Ahluwalia⁷, George A. Tomlinson⁸ and Karen Tu⁴, ¹University of Toronto, Toronto, ON, Canada, ²Rheumatology, University of Toronto, Toronto, ON, Canada, ³Clinical Epidemiology, Research Institute of the McGill University Health Ctre, Montreal, QC, Canada, ⁴Institute for Clinical Evaluative Sciences, Toronto, ON, Canada, ⁵Southlake Regional Health Centre, Newmarket, ON, Canada, ⁶Preventive Med and Biostatisti, University of Toronto, Toronto, ON, Canada, ⁷William Osler Health Center, Brampton, ON, Canada, ⁸Dept of Medicine/Rheumatology, Toronto General Hospital, Toronto, ON, Canada
Background/Purpose: The use of population-based health administrative databases in rheumatology research is well established, but there are ongoing concerns about validity. To date, previous validation…
Abstract Number: 927 • 2012 ACR/ARHP Annual Meeting
Shared Decision Making in Secondary Care: Rheumatologic Patient’s Perspective
Raphael Battisti¹, Thiago D. Baumgratz², Mirella Cuziol³, Ana Carolina Reiff Janini³, Roger A. Levy⁴ and Mirhelen M. Abreu⁵, ¹Universidade Federal de São Carlos, Medical Student, São Carlos, Brazil, ²Medicine, Medical Student, São Carlos, Brazil, ³Medicine, Medical Student at Universidade Federal de São Carlos, São Carlos, Brazil, ⁴Medicine, Hospital Universitário Pedro Ernesto, Rio de Janeiro, Brazil, ⁵Universidade Federal de São Carlos, São Carlos SP, Brazil
Background/Purpose: This cross-sectional study aimed to analyze the willingness for shared decision making (SDM) of rheumatologic patients. Methods: All rheumatic disease patients assisted at a…
Abstract Number: 928 • 2012 ACR/ARHP Annual Meeting
Is There an Optimal Treatment Strategy for Disease-Modifying-Antirheumatic-Drug Naïve Patients with Rheumatoid Arthritis?
Roopa Akkineni¹ and Daniel A. Albert², ¹Rheumatology, Dartmouth Hitchcock Medical Center, Lebanon, NH, ²Medicine/Rheumatology, Dartmouth-Hitchcock Medical Center, Lebanon, NH
Background/Purpose: There is a lack of head-to-head clinical trial data to determine the most effective treatment for rheumatoid arthritis (RA). However, these trials have had…
Abstract Number: 929 • 2012 ACR/ARHP Annual Meeting
Epidemiology of the US National Burden of Pediatric Lupus Hospitalization From 2000-2009
Andrea Knight¹, Pamela Weiss², Knashawn Morales³ and Ron Keren⁴, ¹Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, ²Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA, ³University of Pennsylvania, Philadelphia, PA, ⁴Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: Studies indicate that of 11% of adult hospitalizations are related to systemic lupus erythematosus (SLE), with an average charge of $10,000 US per hospitalization…
Abstract Number: 930 • 2012 ACR/ARHP Annual Meeting
Disease Burden and Cost of Illness in SLE During 8 Years Follow up
Andreas Jönsen¹, Anders A. Bengtsson², Frida Hjalte³, Minna Willim⁴, Ragnar Ingvarsson¹, Ulf Persson⁵, Ingemar F. Petersson⁶ and Ola Nived⁷, ¹Department of Clinical Sciences Lund, Section of Rheumatology, Lund, Sweden, ²Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund, Sweden, ³The Swedish Institute for Health Economics,, Health Economy, Lund, Sweden, ⁴Department of Clinical Sciences Malmö, Section of Rheumatology, Lund University, Malmö, Sweden, ⁵The Swedish Institute for Health Economics,, Lund, Sweden, ⁶Musculoskeletal Scienes, Department of Orthopedics, Clinical Sciences, Lund, Sweden, ⁷Department of Clinical Science, Lund University, Rheumatology, Lund, Sweden
Background/Purpose: To study the annual direct and indirect costs in SLE in a cohort, from a defined area in southern Sweden, and to find potential…
Abstract Number: 931 • 2012 ACR/ARHP Annual Meeting
Health Care Utilization Among Medicaid Enrollees with Systemic Lupus Erythematosus Preceding the Development of End-Stage Renal Disease: Sociodemographic Variation
Candace H. Feldman¹, Linda T. Hiraki², Graciela S. Alarcon³, Jinoos Yazdany⁴, Jun Liu⁵, Michael A. Fischer⁶, Wolfgang C. Winkelmayer⁷ and Karen H. Costenbader⁸, ¹Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ²Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital/ Harvard School of Public Health, Boston, MA, ³Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, ⁴Medicine, University of California, San Francisco, San Francisco, CA, ⁵Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Harvard Medical School, Boston, Boston, MA, ⁶Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Boston, MA, ⁷Division of Nephrology, Stanford University School of Medicine, Stanford, CA, ⁸Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Extreme sociodemographic disparities exist among systemic lupus erythematosus (SLE) patients in the development of end-stage renal disease (ESRD) from lupus nephritis. Better resource allocation…
Abstract Number: 932 • 2012 ACR/ARHP Annual Meeting
Medical Costs and Health Care Resource Use in Patients with Systemic Lupus Erythematosus in an Insured Population
Daniel Furst¹, Ann E. Clarke², Ancilla W. Fernandes³, Tim Bancroft⁴, Kavita Gajria³, Warren Greth⁵ and Serban R. Iorga⁴, ¹Div of Rheumatology, UCLA Medical School, Los Angeles, CA, ²McGill University, Montreal, QC, Canada, ³MedImmune LLC, Gaithersburg, MD, ⁴OptumInsight, Eden Prairie, MN, ⁵Clinical Development, MedImmune, LLC, Gaithersburg, MD
Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that may affect multiple organ systems. The clinical manifestations of SLE are heterogeneous, and subjects…
Abstract Number: 933 • 2012 ACR/ARHP Annual Meeting
Economic Burden of Systemic Lupus Erythematosus by Flare Severity in a Commercially Insured Population in the United States
Siva Narayanan¹, Emily Durden², Alan Oglesby³, Paul Juneau⁴ and Kathleen L. Wilson⁵, ¹Global Health Economics and Outcomes Research and Epidemiology, Human Genome Sciences, Inc., Rockville, MD, ²Thomson Reuters, Austin, TX, ³GlaxoSmithKline, Research Triangle Park, NC, ⁴Truven Health Analytics, Washington, DC, ⁵Thomson Reuters Healthcare, Cambridge, MA
Background/Purpose: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease with an unpredictable disease course with sporadic periods of illness (flares). Little is known about…
Abstract Number: 894 • 2012 ACR/ARHP Annual Meeting
Genetic Variants in the IL-4 and IL-4 Receptor Genes in Association with the Severity of Joint Damage in Rheumatoid Arthritis: A Study in Seven Cohorts
A. Krabben¹, A. G. Wilson², R. Knevel¹, A. Zhernakova³, E. Brouwer³, E. Lindqvist⁴, T. Saxne⁴, G. Stoeken-Rijsbergen¹, J. A. B. van Nies¹, D. P. C. de Rooy¹, T.W.J. Huizinga¹, B. P. C. Koeleman⁵, R. E. M. Toes¹, P. K. Gregersen⁶ and A. H. M. van der Helm-van Mil¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Infection & Immunity, University of Sheffield, Sheffield, United Kingdom, ³Rheumatology and Clinical Immunology, University of Groningen, University Medical Center, Groningen, Netherlands, ⁴Rheumatology, Lund University, Lund, Sweden, ⁵Medical Genetics, University Medical Center Utrecht, Utrecht, Netherlands, ⁶Genomics and Human Genetics, Feinstein Institute Medical Research and North Shore-Long Island Jewish Health System, Manhasset, NY
Background/Purpose: The severity of RA is reflected by the severity of radiological joint destruction. It is highly variable between patients and up to 58% of…
Abstract Number: 895 • 2012 ACR/ARHP Annual Meeting
Transcriptomics of Synovial Tissue of Early Human (CHECK) and Experimental OA Identify Pathways Associated with Cartilage Damage
Arjen B. Blom¹, Peter L.E.M. van Lent², Martijn H. van den Bosch¹, Hans Cats³, Peter M. van der Kraan¹ and Wim B. van den Berg⁴, ¹Rheumatology Research & Advanced Therapeutics, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ²Rheumatology Research & Advanced Therpeutics, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ³Rheumatology, Rheumatology Centre Sint Maartenskliniek, Nijmegen, Netherlands, ⁴Rheumatology Research and Advanced Therapeutics, Department of Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
Background/Purpose: Many osteoarthritis (OA) patients show synovial inflammation, even relatively early during the disease. Mechanisms through which synovial activation contributes to the joint pathology that…
Abstract Number: 896 • 2012 ACR/ARHP Annual Meeting
Tyro3, Axl, MerTK-Receptor Activation by Gas6 or Pros1 Gene Delivery, ameliorates Collagen-induced arthritis
Fons A.J. van de Loo¹, Ben T. van Den Brand², Shahla Abdollahi-Roodsaz³, Eline A. Vermeij⁴, Miranda B. Bennink⁴, Onno J. Arntz⁵ and Wim B. van den Berg⁶, ¹Rheumatology Research & Advanced Therapeutics, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ²Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ³Rheumatology Research and Advanced Therapeutics, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ⁴Rheumatology Research and Advanced Therapeutics, Department of Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ⁵Rheumatology Research and Advanced Therapeutics, Department of Rheumatology, Nijmegen, Netherlands, ⁶Experimental Rheumatology (272), Radboud university medical center, Nijmegen, Netherlands
Background/Purpose: Insufficient controlled activation of innate immunity by cytokines and pattern recognition receptors could develop into auto-immune diseases. Stimulation of dendritic cells via the Axl receptor…

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