Abstracts Archive - Page 2530 of 2607 - ACR Meeting Abstracts

Abstract Number: 1104 • 2012 ACR/ARHP Annual Meeting
The Association of Demographic, Modifiable, Structural and Biomechanical Risk Factors with Medial and Lateral Patellofemoral Joint Structural Damage On MRI: The Multicenter Osteoarthritis Study
Joshua J. Stefanik¹, Ke Wang², K. Douglas Gross³, Frank Roemer⁴, John A. Lynch⁵, Neil Segal⁶, Cora E. Lewis⁷, Michael C. Nevitt⁸, Ali Guermazi⁹ and David T. Felson¹⁰, ¹Clinical Epidemiology, Boston University, Boston, MA, ²Biostatistics, Boston University, Boston, MA, ³Physical Therapy, MGH Institute of Health Professions, Boston, MA, ⁴Klinikum Augsburg, Augsburg, Germany, ⁵Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA, ⁶Orthopaedics and Rehabilitation, University of Iowa, Iowa City, IA, ⁷Preventive Medicine, University of Alabama, Birmingham City, Birmingham, AL, ⁸Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, ⁹Radiology, Boston University, Boston, MA, ¹⁰Boston University, Boston, MA
Background/Purpose: Past investigations into risk factors for patellofemoral joint (PFJ) osteoarthritis (OA) have been limited by the use of radiography, which is insensitive to identify…
Abstract Number: 1105 • 2012 ACR/ARHP Annual Meeting
Lateral Tibio-Femoral Shift Related to Medial Knee Osteoarthritis
Roy H. Lidtke¹, Berna Goker², Abdurrahman Tufan³, Laura E. Thorp⁴ and Joel A. Block¹, ¹Section of Rheumatology, Rush University Medical Center, Chicago, IL, ²Internal Medicine-Rheumatology, Gazi University Medical School, Ankara, Turkey, ³Internal Medicine-Rheumatology, Gazi University School of Medicine, Ankara, Turkey, ⁴Anatomy and Cell Biology, Rush University Medical Center, Chicago, IL
Background/Purpose: Medial knee osteoarthritis (MKOA) has been shown to be related to malalignment of the knee joint with several radiographs used to quantify the abnormality.…
Abstract Number: 1106 • 2012 ACR/ARHP Annual Meeting
Evaluation of Foot Posture and Plantar Pressure Changes in Knee Osteoarthritis: Preliminary Report
Necati Balci and Lale Cerrahoglu, PMR Department, Celal Bayar University Medical School, Manisa, Turkey
Background/Purpose: Disturbances of weight bearing and walking pattern occur in patients with knee osteoarthritis (OA) due to impairments in knee joint. These impairments may lead…
Abstract Number: 1107 • 2012 ACR/ARHP Annual Meeting
Baseline Knee Flexion Pain, Age and Joint Line Tenderness Predict the Progression of Asymptomatic, Radiographic Knee Osteoarthritis to Symptomatic Knee Osteoarthritis Over 5 Years
Abhiram Gande¹ and James J. Irrgang², ¹Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, ²Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Knee Osteoarthritis (OA) is the most prevalent form of OA. Historically, not all people who have tell-tale signs of radiographic knee osteoarthritis progress to…
Abstract Number: 1108 • 2012 ACR/ARHP Annual Meeting
A Randomized Controlled Trial of Hylan G-F 20 for the Treatment of Carpometacarpal Osteoarthritis
Lisa A. Mandl¹, Scott Wolfe², Aaron Daluiski², Robert N. Hotchkiss³, Stephen L. Lyman⁴ and Jeffrey N. Katz⁵, ¹Rheumatology, Hospital for Special Surgery, New York, NY, ²Department of Orthopedics, Hospital For Special Surgery, New York, NY, ³Department of Orthopedics, Hospital for Special Surgery, New York, NY, ⁴Research, Hospital Special Surgery, New York, NY, ⁵Rheumatology and Orthopedics, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Painful carpometacarpal osteoarthritis (CMC OA) is associated with substantial impairment, and is often unresponsive to medical treatment. Hylan G-F 20 has been shown…
Abstract Number: 1109 • 2012 ACR/ARHP Annual Meeting
Effects of Strontium Ranelate On Hand Osteoarthritis – Analysis of Data From the Sekoia Trial
E. Maheu¹, C. Cadet² and F. Berenbaum³, ¹AP-HP, Saint-Antoine Hospital, Rheumatology Department and DHU i2B, Paris, France, ²Rheumatology, Paris, France, ³Rheumatology, AP-HP St Antoine Hospital, Paris, France
Background/Purpose: Strontium ranelate (SrRan) has shown the ability to reduce radiological progression of knee osteoarthritis (OA) over 3 years. Patients with knee OA are also…
Abstract Number: 1110 • 2012 ACR/ARHP Annual Meeting
Radiologic Progression in Hand Osteoarthritis (OA) Over 2.6 Years – Data From the Sekoia Trial
Emmanuel Maheu¹, Christian Cadet² and Francis Berenbaum¹, ¹Rheumatology, AP-HP, St Antoine Hospital, Paris, France, ²Rheumatology, Paris, France
Background/Purpose: Hand OA is a frequent polyarticular disease. Few is known with respect to its radiological progression over time, which in addition is difficult to…
Abstract Number: 1111 • 2012 ACR/ARHP Annual Meeting
Erosive Evolution in Hand Osteoarthritis Is Associated with Incident Joint Tenderness Independent of MRI-Defined Bone Marrow Lesions and Synovitis
Ida K. Haugen¹, Barbara Slatkowsky-Christensen¹, Pernille Boyesen¹, Sølve Sesseng², Désirée van der Heijde³ and Tore K. Kvien⁴, ¹Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Radiology, Diakonhjemmet Hospital, Oslo, Norway, ³Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose: Previous studies have shown no association between increased amount of radiographic hand osteoarthritis (OA) resulting in more hand pain/disabilities. In this longitudinal study, our…
Abstract Number: 1112 • 2012 ACR/ARHP Annual Meeting
Patients with Erosive Osteoarthritis Have Less Extensive Synovitis Than Patients with Rheumatoid Arthritis On Histopathology
Allen P. Anandarajah¹, Stephen Kates², Kate Burns³ and Ellen Giampoli⁴, ¹Dept of Rheumatology, Univ of Rochester Medical Ctr, Rochester, NY, ²Orthopedic Surgery, University of Rochester Medical Center, Rochester, NY, ³Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, ⁴Pathology, University of Rochester Medical Ctr, Rochester, NY
Background/Purpose: Patients with erosive osteoarthritis (EOA) often develop disfiguring deformities and associated decline in hand function. We have previously demonstrated that synovitis was a common…
Abstract Number: 1113 • 2012 ACR/ARHP Annual Meeting
Characterization of Lumbar Spine Individual Radiographic Features in African American and White Women and Men: The Johnston County Osteoarthritis Project
Adam P. Goode¹, Amanda E. Nelson², Kelli D. Allen³, Jordan Renner⁴, Timothy S. Carey⁵ and Joanne M. Jordan⁶, ¹Community and Family Medicine, Duke University, Durham, NC, ²University of North Carolina Thurston Arthritis Research Center, Chapel Hill, NC, ³Health Services Research, Duke and Durham VA Medical Center, Durham, NC, ⁴UNC School of Medicine, University of North Carolina, Chapel Hill, NC, ⁵UNC School of Medicine, Cecil G. Sheps Center for Health Services Research University of North Carolina, Chapel Hill, NC, ⁶Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC
Background/Purpose: Race and gender differences have been found to exist in hip and knee osteoarthritis (OA). Whether such differences occur with lumbar spine individual radiographic…
Abstract Number: 1114 • 2012 ACR/ARHP Annual Meeting
Prevalence of Radiographic and Symptomatic Hip Osteoarthritis in an Urban US Population: The Framingham Osteoarthritis Study
Katherine D. Linsenmeyer¹, Ali Guermazi², Kyu-Chan Kim¹, David T. Felson³, Mary M. Clancy⁴ and Steven C. Vlad⁵, ¹Internal Medicine, Boston Medical Center, Boston, MA, ²Radiology, Boston University, Boston, MA, ³Boston University, Boston, MA, ⁴School of Medicine, Boston University, Boston, MA, ⁵Clinical Epidemiology, Boston University, Boston, MA
Background/Purpose: There are few studies of hip osteoarthritis (OA) in the United States and none in the last 35 years that have addressed the prevalence…
Abstract Number: 1115 • 2012 ACR/ARHP Annual Meeting
Relation Between Hip Dysplasia, Pain, and Osteoarthritis in a Cohort of Patients with Hip Symptoms
Johanne Morvan¹, Ronan Bouttier², Bernard Mazieres³, Evelyne Verrouil³, Jacques Pouchot⁴, Anne-Christine Rat⁵, Joel Coste⁶ and Alain Saraux⁷, ¹Rheumatology, CH Quimper, Quimper, France, ²Radiology, CHU Brest, Brest, ³Rhumatologie, Hopital de Rangueil, Toulouse, FRANCE, France, ⁴Medecine Interne, Hopital Louis Mourier, Colombes, FRANCE, France, ⁵Rheumatology, Nancy Teaching Hospital, Nancy, France, ⁶Université de Lorraine, Paris Descartes University, APEMAC, EA 4360, F- 54 000, France, Nancy, France, ⁷Department of rheumatology and unit of immunology (EA 2216), Université Brest Occidentale, Brest, France
Background/Purpose: The relationship between acetabular dysplasia (HD) and hip osteoarthritis remains unclear, especially for mild forms of dysplasia. Our objectives were to estimate the prevalence…
Abstract Number: 1076 • 2012 ACR/ARHP Annual Meeting
FLIP in Dendritic Cells May Regulate Hematopoietic Homeostasis and Modulating Inflammation and Immunity
Qi Quan Huang¹, Robert Birkett², Harris R. Perlman³ and Richard M. Pope⁴, ¹Medicine/Rheumatology, Northwestern University, Chicago, IL, ²Division of Rheumatology, Department od Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Feinberg School of Medicine, Northwestern University, Chicago, IL, ⁴Rheumatology, Northwestern University Feinberg school of Medicine, Chicago, IL
Background/Purpose: We previously demonstrated that FLIP in myeloid linage cells is necessary for neutrophil homeostasis and macrophage differentiation. Therefore studies were performed to determine the…
Abstract Number: 1077 • 2012 ACR/ARHP Annual Meeting
p21 Promotes Inflammatory Arthritis Resolution by Facilitating Alternative Activation of Macrophages
Angelica K. Gierut¹, Carla M. Cuda², Alexander V. Misharin³, Rana Saber³ and Harris R. Perlman⁴, ¹Rheumatology, Northwestern Med Faculty Found, Chicago, IL, ²Medicine / Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Medicine/Rheumatology, Northwestern University, Chicago, IL, ⁴Feinberg School of Medicine, Northwestern University, Chicago, IL
Background/Purpose: Current understanding of pathogenesis suggests that RA is mainly a Th1 mediated process that promotes robust inflammatory cytokine production by “classically” activated macrophages. …
Abstract Number: 1078 • 2012 ACR/ARHP Annual Meeting
Prolactin Is Increased in Responders to Anti-TNFá Treatment and the Role of the Prolactin Receptor in Rheumatoid Arthritis
Man Wai Tang¹, Danielle Marie Gerlag², Veronica Codullo³, Elsa Vieira-Sousa⁴, Anne Q. Reuwer⁵, Marcel T. Twickler⁵, Robert B. M. Landewé⁶ and Paul Peter Tak⁷, ¹Division of Clinical Immunology and Rheumatology & Department of Experimental Immunology, Academic Medical Center / University of Amsterdam, Amsterdam, Netherlands, ²Clinical Immunology and Rheumatology, Academic Medical Center, Amsterdam, Netherlands, ³Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy, ⁴Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal, ⁵Vascular Medicine, Academic Medical Center/University of Amsterdam, Amsterddam, Netherlands, ⁶Academic Medical Center/University of Amsterdam & Atrium Medical Center, Amsterdam, Netherlands, ⁷Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands
Background/Purpose: Rheumatoid arthritis (RA) is the most common rheumatic disease which mainly affects women. In the last decade, it is known that prolactin (PRL) is…

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