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  • Abstract Number: 1394 • 2012 ACR/ARHP Annual Meeting

    Health Status Burden and Impact of Fatigue On Patient Functioning in SLE Patients From a Phase 1b Study

    Michelle Petri1, Ariane K. Kawata2, Ancilla W. Fernandes3, Kavita Gajria4, Warren Greth5 and Asha Hareendran6, 1Johns Hopkins University School of Medicine, Baltimore, MD, 2United Biosource Corporation, Bethesda, MD, 3MedImmune, LLC, Gaithersburg, MD, 4MedImmune LLC, Gaithersburg, MD, 5Clinical Development, MedImmune, LLC, Gaithersburg, MD, 6United Biosource Corporation, London, MD, United Kingdom

     Background/Purpose: Systemic Lupus Erythematosus (SLE) has a significant impact on patient's quality of life. Fatigue is the most common symptom of SLE and affects between…
  • Abstract Number: 1395 • 2012 ACR/ARHP Annual Meeting

    The Validation of a New Simple Disease Activity Tool in Systemic Lupus Erythematosus (SLE): The Lupus Activity Scoring Tool (LAST) As Compared to the Sledai Selena Modification

    Majed M. Khraishi1, Rana Aslanov2 and Krista Fudge3, 1Nexus Clinical Research, Memorial University of Newfoundland, St Johns, NF, Canada, 2Clinical Epidemiology Department, Faculty of Medicine, Memorial University of Newfoundland, St.John's, NF, Canada, 3Medical Consultants of West Newfoundland, Western Memorial Hospital, Corner Brook, NF, Canada

    Background/Purpose: SLE is a chronic autoimmune disease with variable manifestations. New developments in the understanding and treatment of SLE mandated closer monitoring of the disease…
  • Abstract Number: 1356 • 2012 ACR/ARHP Annual Meeting

    Gender Differences Among Spondylitis Associated with Psoriasis, Inflammatory Bowel Disease and Primary Ankylosing Spondylitis

    Margarita Landi1, Hernan Maldonado-Ficco2, Jose A. Maldonado-Cocco2, Gustavo Citera3, Pablo Arturi2, Percival Sampaio-Barros4, Diana Flores5, Ruben Burgos-Vargas6, Helena Santos7, Jose Chavez-Corrales8, Daniel Palleiro9, Miguel A. Gutierrez10, Elsa Vieira-Sousa11, Fernando Pimentel-Santos12, Sergio O. Paira13, Alberto Berman Sr.14, Janitzia Vazquez-Mellado15, Eduardo Collantes-Estevez16 and On behalf of RESPONDIA Group17, 1Instituto de Rehabilitacion Psicofisica, Buenos Aires, Argentina, 2Rheumatology, Instituto de Rehabilitacion Psicofisica and Fundacion Reumatologica Argentina, Buenos Aires, Argentina, 3Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 4Rheumatology, University of Sao Paulo School of Medicine, Sao Paulo, Brazil, 5Rheumatology, Hospital Universitario, Monterrey, Mexico, 6Rheumatology, Hospital General de Mexico, Mexico DF, Mexico, 7Rheumatology, Instituto Português de Reumatologia, Lisboa, Portugal, 8Rheumatology, Hospital Nacional E. Rebagliti-ESSALUD, Lima, Peru, 9Rheumatology, Instituto Nacional de Reumatologia, Montevideo, Uruguay, 10Rheumatology and Inmunology, Pontificia Universidad Catolica de Chile, Santiago, Chile, 11Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal, 12Rheumatology, Centro Hospitalar de Lisboa Ocidental, Hospital Egas Moniz, Lisboa, Portugal, 13Hospital Jose María Cullen, Santa Fe SFE S3000BFP, Argentina, 14Internal Medicine, Hospital Padilla, Tucuman, Argentina, 15Rheumatology, Hospital General de Mexico, Mexico city, Mexico, 16Depatamento de Medicina, IMIBIC-Reina Sofia Hospital, Cordoba 14012, Spain, 17Buenos Aires

    Background/Purpose: Differences regarding gender in primary Ankylosing Spondylitis are well known. However, there is less evidence regarding Spondylitis Associated with Psoriasis and that associated with…
  • Abstract Number: 1357 • 2012 ACR/ARHP Annual Meeting

    Psoriatic Arthritis and Biologic Therapy: Treatment Response, Drug Survival and Outcome After Switching

    Dinny Wallis1, Deepak Jadon2, William Tillett2, Nicola Waldron2, Charlotte Cavill3, Neil McHugh4 and Eleanor Korendowych2, 1Rheumatology, Royal National Hospital for Rheumatic Diseases NHS Foundation Trust, Bath, United Kingdom, 2Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 3Rheumatology, Bath Institute for Rheumatic Disease, Bath, United Kingdom, 4Department of Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom

    Background/Purpose: Data on longer term efficacy and tolerance of biologic therapies in psoriatic arthritis (PsA) are emerging.  Persistence with the first TNF inhibitor (TNFi) at…
  • Abstract Number: 1358 • 2012 ACR/ARHP Annual Meeting

    Performance of Remission Criteria and Activity Indices in Psoriatic Arthritis

    Maria L. Acosta Felquer1, Leandro Ferreyra Garrott2, Erika Catay3, Josefina Marin4, Marina Scolnik5, Maria Victoria Garcia5, Santiago Ruta2, Mirtha Sabelli6, Zaida Bedran6, Javier Rosa3, Luis J. Catoggio7 and Enrique R. Soriano7, 1Internal Medicine, Rheumatology Section, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 2Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 3Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 4Internal Medicine, Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 5Internal Services, Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 6Rheumatology Section, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 7Internal Medicine, Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM. Catoggio, Buenos Aires, Argentina

    Background/Purpose: Remission criteria and activity indices used in rheumatoid arthritis (RA) are often applied in psoriatic arthritis (PsA). Although indices have been specifically developed for…
  • Abstract Number: 1359 • 2012 ACR/ARHP Annual Meeting

    Comparison of Sacroiliac MRI Evaluation Versus Sacroiliac x-Rays in Peripheral Psoriatic Arthritis: Evidence of Silent Disease and Lack of Association to HLA-B27

    Jose Luis Fernandez-Sueiro1, JA Pinto1, S. Pertega-Diaz2, E. Gonzalez3 and Francisco J. Blanco V4, 1Rheumatology Division, Complejo Hospitalario Universitario La Coruña, La Coruña, Spain, 2Epidemiology and Statistics, Complejo Hospitalario Universitario La Coruña, La Coruña, Spain, 3Rheumatology, Complejo Hospitalario Universitario La Coruña, La Coruña, Spain, 4Rheumatology Service, INIBIC-Hospital Universitario A Coruña, A Coruña, Spain

    Background/Purpose: Although there are no consensus on how to define spinal involvement in axial psoriatic artritis (axPsA), our data suggest that the presence of spinal…
  • Abstract Number: 1360 • 2012 ACR/ARHP Annual Meeting

    Spinal Involvement in Axial Psoriatic Artritis Is Not Determined by the Presence of HLA-B27. Is the HLA-B27 Arm of the Axial Spa Criteria Reliable for Classifying Axial Psoriatic Arthritis?

    Jose Luis Fernandez-Sueiro1, JA Pinto1, S. Pertega-Diaz2, E. Gonzalez3, Ignacio Rego-Perez4, Francisco J. de Toro-Santos5 and Francisco J. Blanco V6, 1Rheumatology Division, Complejo Hospitalario Universitario La Coruña, La Coruña, Spain, 2Epidemiology and Statistics, Complejo Hospitalario Universitario La Coruña, La Coruña, Spain, 3Rheumatology, Complejo Hospitalario Universitario La Coruña, La Coruña, Spain, 4INIBIC-Hospital Universitario A Coruña. Genomic Group. Rheumatology Division., A Coruña, Spain, 5Reumatology, Complejo Hospitalario Universitario Juan Canalejo, Universidad de la Coruña, La Coruña, Spain, 6Rheumatology Service, INIBIC-Hospital Universitario A Coruña, A Coruña, Spain

    Background/Purpose: There is a debate whether axial psoriatic arthritis (axPsA) is an ankylosing spondylitis with psoriasis, however due to the fact that PsA has characteristic…
  • Abstract Number: 1361 • 2012 ACR/ARHP Annual Meeting

    Disease Burden Is Comparable in Patients with Non-Radiographic Axial Spondyloarthritis and Ankylosing Spondylitis

    Joachim Sieper1, Désirée van der Heijde2, Dirk Elewaut3, Aileen L. Pangan4 and Jaclyn K. Anderson4, 1Rheumatology, Charité Universitätesmedizin Berlin, Berlin, Germany, 2Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Rheumatology, Department of Rheumatology Ghent University Hospital, Ghent, Belgium, 4Abbott Laboratories, Abbott Park, IL

    Background/Purpose: Chronic back pain and functional impairment are disease characteristics common to all patients (pts) with axial spondyloarthritis (SpA), regardless of the presence of radiographic…
  • Abstract Number: 1362 • 2012 ACR/ARHP Annual Meeting

    Evaluation of Spondyloarthritis activity  by the Patients and the Physicians: ASDAS, Basdai, PASS and Flare

    Marie Godfrin-Valnet1, Clément Prati2, Marc Puyraveau3, Eric Toussirot4, Helene Letho-Gyselinck5 and Daniel Wendling5, 1Rheumatology, CHU, Besançon, France, 2Service de Rhumatologie, CHU J Minjoz, Besancon, France, 3Clinical Methodology Center, CHU, Besançon, France, 4Université de Franche Comté , CHRU, CIC Biotherapy 506 and Rheumatology and EA 4266 Pathogens and Inflammation, Besançon, France, 5Service de Rhumatologie, Minjoz University Hospital, Besancon, France

    Background/Purpose: Objectives: to define thresholds of the ASDAS corresponding to the PASS (Pateint Acceptable Symptomatic State) and to the thresholds of activity of the disease…
  • Abstract Number: 1363 • 2012 ACR/ARHP Annual Meeting

    Validation of the Self-Administered Comorbidity Questionnaire in Patients with Ankylosing Spondylitis

    Carmen Stolwijk1, A.M. Van Tubergen2, Sofia Ramiro3, Ivette Essers1, Marc Blaauw1, Désirée van der Heijde4, Robert B. M. Landewé5, Filip Van den Bosch6, Maxime Dougados7 and Annelies Boonen8, 1Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, 2Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands, 3Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam, The Netherlands and Hospital Garcia de Orta, Almada, Portugal, 4Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 5Academic Medical Center/University of Amsterdam & Atrium Medical Center, Amsterdam, Netherlands, 6Rheumatology, Ghent University Hospital, Ghent, Belgium, 7Rheumatology B Department, Paris-Descartes University, APHP, Cochin Hospital, Paris, France, 8Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands

    Background/Purpose: Comorbidities can importantly influence the results of clinical studies on functional outcomes as they may act as confounders or effect modifiers. The generic self-administered…
  • Abstract Number: 1364 • 2012 ACR/ARHP Annual Meeting

    Development, Sensibility and Reliability of a New Case-Finding Questionnaire, the Toronto Axial Spondyloarthritis Questionnaire in Inflammatory Bowel Disease

    Khalid A. Alnaqbi1, Zahi Touma1, Laura A. Passalent2, Sindhu R. Johnson1, George A. Tomlinson3, Adele Carty1 and Robert D. Inman1, 1Rheumatology, Toronto Western Hospital, Toronto, ON, Canada, 2Allied Health, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, 3Dept of Medicine/Rheumatology, Toronto General Hospital, Toronto, ON, Canada

    Background/Purpose: Inflammatory bowel disease (IBD) encompasses Crohn's disease, ulcerative colitis, and indeterminate colitis. Articular involvement [(peripheral arthritis and axial spondyloarthritis (axSpA)] is the most common…
  • Abstract Number: 1365 • 2012 ACR/ARHP Annual Meeting

    Double-Blind, Placebo-Controlled, 28-Week Trial of Efficacy and Safety of Infliximab Plus Naproxen Vs Naproxen Alone: Results From the Infliximab As First Line Therapy in Patients with Early, Active Axial Spondyloarthritis Trial, Part I

    Joachim Sieper1, Jan Lenaerts2, Jürgen Wollenhaupt3, Vadim Mazurov4, L. Myasoutova5, Sung-Hwan Park6, Yeong W. Song7, Ruji Yao8, Denesh Chitkara8 and Nathan Vastesaeger9, 1Charité, University Medicine Berlin, Berlin, Germany, 2Reuma-instituut, Hasselt, Belgium, 3Schön-Klinik, Hamburg, Germany, 4St. Petersburg Medical Academy, St. Petersburg, Russia, 5Kazan State Medical University, Kazan, Russia, 6Catholic University of Korea, Seoul, South Korea, 7Seoul National University, Seoul, South Korea, 8Merck Sharp and Dohme, Kenilworth, NJ, 9Merck Sharp & Dohme, Brussels, Belgium

    Background/Purpose: Efficacy of anti–tumor necrosis factor (TNF) therapy in patients with axial spondyloarthritis (SpA) has been tested only in patients who are refractory to NSAIDs.…
  • Abstract Number: 1366 • 2012 ACR/ARHP Annual Meeting

    Golimumab Administered Subcutaneously Every 4 Weeks in Chinese Patients with Active Ankylosing Spondylitis: Week 24 Safety and Efficacy Results From a Randomized, Placebo – Controlled Study

    Chunde Bao1, Feng Huang2, Muhammad Asim Khan3, Kaiyin Fei4, Zhong Wu4 and Elizabeth C. Hsia4, 1Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China, 2Dept of Rheumatology, Chinese PLA General Hospital, Beijing, China, 3Medicine/ Rheumatology, Case Western Reserve University Hospital, Cleveland, OH, 4Janssen Research & Development, LLC., Spring House, PA

    Golimumab Administered Subcutaneously Every 4 Weeks in Chinese Patients with Active Ankylosing Spondylitis: Week 24 Safety and Efficacy Results From a Randomized, Placebo-Controlled StudyBackground/Purpose: This…
  • Abstract Number: 1367 • 2012 ACR/ARHP Annual Meeting

    Clinical Features and Treatment Results of Japanese Patients with SAPHO (Synovitis-Acne-Pustulosis-Hyperostosis-Osteitis) Syndrome

    Hiroki Yabe1, Takashi Kuroiwa1, Aya Nonaka1, Tomomi Tsutsumi1, Tadashi Sakurai1, Masato Moriguchi1, Hisaji Oshima2, Kensuke Ochi3 and Chihiro Terai1, 1Division of Rheumatology, Jichi Medical University Saitama Medeical Center, Saitama City, Japan, 2Connective Tissue Diseases, Tokyo Medical Ctr, Tokyo, Japan, 3Department of Orthopaedic Surgery, Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan

    Background/Purpose: SAPHO syndrome is a disorder characterized by pustular skin lesions and osteoarticular lesions, which was proposed by Chamot et al. in 1987. Clinical studies…
  • Abstract Number: 1368 • 2012 ACR/ARHP Annual Meeting

    Psoriatic Arthritis in South Asians- Comparison with Caucasians of European Descent

    Vinod Chandran1, Arane Thavaneswaran2 and Dafna D. Gladman3, 1Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, 3Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose: The prevalence of psoriatic arthritis (PsA) varies substantially world-wideand is highest among Caucasians of European descent. Studies from India suggest that patients with PsA…
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