Abstract Number: 1515 • 2012 ACR/ARHP Annual Meeting
Pharmacological Blockade of Adenosine A2A Receptors (A2AR) Prevents Radiation-Induced Dermal Injury
Background/Purpose: Ionizing radiation is a commonly used therapeutic modality and following irradiation dermal changes, including fibrosis and atrophy, may lead to such problems as contractures.…Abstract Number: 1516 • 2012 ACR/ARHP Annual Meeting
TSLP Upregulation in Human SSc Skin and Induction of Overlapping Profibrotic Genes and Intracellular Signaling with IL-13 and TGFb
Background/Purpose: to investigate the expression of Thymic Stromal Lymphopoietin (TSLP) in diffuse cutaneous systemic sclerosis (dcSSc) patients and explore its effects in vivo and in vitro…Abstract Number: 1477 • 2012 ACR/ARHP Annual Meeting
Skin Autofluorescence As a Measure of Oxidative Stress in Systemic Sclerosis Is Not Affected by Skin Thickness, Erythema or Melanin
Background/Purpose: Skin autofluorescence (AF) has been suggested as a non-invasive measure of oxidative stress in patients with diabetes and other diseases. We have previously shown…Abstract Number: 1478 • 2012 ACR/ARHP Annual Meeting
Gender-Associated Differences in Disease Characteristics and Outcome in Systemic Sclerosis
Background/Purpose: Although significant female gender predominance is seen in majority of large systemic sclerosis (SSc) cohorts, multiple studies have suggested that male gender generally associates…Abstract Number: 1479 • 2012 ACR/ARHP Annual Meeting
Early Versus Late Onset Systemic Sclerosis: Analysis of 1037 Patients From Rescle Registry
Background/Purpose: Systemic sclerosis (SSc) is characterized by extensive fibrosis, vascular dysfunction and the presence of several auto-antibodies. As in other autoimmune diseases, age at disease…Abstract Number: 1480 • 2012 ACR/ARHP Annual Meeting
The 15% Rule in Scleroderma: A Systematic Review of the Frequency of Organ Complications in Systemic Sclerosis
Background/Purpose : The prevalence of each organ complication in scleroderma (SSc) varies by definition used. However, it is important to be aware of several complications…Abstract Number: 1481 • 2012 ACR/ARHP Annual Meeting
A Double-Blind Placebo-Controlled Crossover Trial of the Alpha-2C Adrenoceptor Antagonist Orm-12741 for Prevention of Cold-Induced Vasospasm in Patients with Systemic Sclerosis
Background/Purpose: The alpha-2C adrenoceptor is thought to play a key role in mediating cold-induced vasospasm in the digits. A previous study suggested that in patients…Abstract Number: 1482 • 2012 ACR/ARHP Annual Meeting
Laser Speckle Contrast Imaging May Help in the Differential Diagnosis of Raynaud’s Phenomenon
Background/Purpose: to investigate blood flow and microvascular reactivity by laser speckle perfusion imager (Perimed, Jarfalla) in consecutive patients affected by Raynaud’s phenomenon at baseline and…Abstract Number: 1483 • 2012 ACR/ARHP Annual Meeting
Predictors of Digital Ulcers in Systemic Sclerosis: Correlation Between Clinical and Hemodynamic Features, Capillaroscopy, Endothelium Dysfunction and Angiogenesis Biomarkers
Background/Purpose: Digital Ulcers (DU) are a major disabling complication of Systemic Sclerosis (SSc) interfering with personal and professional life of our patients. The aim of…Abstract Number: 1484 • 2012 ACR/ARHP Annual Meeting
Investigating Determinants of Subjective and Objective Assessments of Peripheral Vascular Function in Primary Raynaud’s Phenomenon and Systemic Sclerosis
Background/Purpose: The Raynaud’s condition score (RCS) diary is recommended for use in clinical trials of Raynaud’s phenomenon (RP) and systemic sclerosis (SSc). We report the…Abstract Number: 1485 • 2012 ACR/ARHP Annual Meeting
Patients with Very Early Diagnosis of Systemic Sclerosis (VEDOSS) Present Esophageal and Anorectal Involvement: Data From a Single Centre
Background/Purpose: Systemic Sclerosis (SSc) affects gastrointestinal tract in more than 80% of patients. Esophageal involvement is the most common manifestation with a prevalence ranging between…Abstract Number: 1486 • 2012 ACR/ARHP Annual Meeting
Poor Outcome in Patients with Systemic Sclerosis and Myocardial Involvement: A Combined Approach Based On Clinical and Laboratory Findings, EKG-Holter and Cardiac Magnetic Resonance
Background/Purpose: Cardiac involvement is a relevant prognostic determinant in Systemic Sclerosis (SSc), but the diagnosis is often delayed due to the lack of a specific…Abstract Number: 1487 • 2012 ACR/ARHP Annual Meeting
Incidence of Fibromyalgia Syndrome in Systemic Sclerosis and Rheumatoid Arthritis. Comparative Results According to Clinical Diagnosis, Screening Test with Fibromyalgia Rapid Screening Tool, Diagnosis with ACR1990 and ACR 2010 Criteria
Background/Purpose: Fibromyalgia (FMS) is a chronic widespread pain condition that may be associated with inflammatory chronic disorders like rheumatoid arthritis (RA) and systemic sclerosis (SSc).…Abstract Number: 1488 • 2012 ACR/ARHP Annual Meeting
Prevalence and Risk Factors of Low Bone Mineral Density in Chinese Patients with Systemic Sclerosis: A Case-Control Study
Background/Purpose: To study the prevalence and risk factors of low bone mineral density (BMD) in patients with systemic sclerosis (SSc). Methods: Consecutive patients who fulfilled…Abstract Number: 1489 • 2012 ACR/ARHP Annual Meeting
Peripheral Neuropathy: A Complication of Systemic Sclerosis
Background/Purpose: We performed bedside testing for peripheral neuropathy in our Systemic Sclerosis (SSc) population to determine whether foot care guidelines should be developed for SSc. …
ACR Meeting Abstracts