Abstracts Archive - Page 2500 of 2607 - ACR Meeting Abstracts

Abstract Number: 1575 • 2012 ACR/ARHP Annual Meeting
The Impact of Targeted Exercise Intervention On Health Outcomes in Rheumatoid Arthritis
Laura J. Durcan¹, Fiona Wilson², Finbar (Barry) D. O'Shea³ and Gaye Cunnane⁴, ¹Rheumatology, Mater Misercordiae University Hospital, Dublin 7, Ireland, ²Physiotherapy, Trinity College Dublin, Dublin, Ireland, ³Rheumatology Dept, St James's Hospital, Dublin, Ireland, ⁴Dept of Rheumatology, St James's Hospital, Dublin, Ireland
Background/Purpose: Increased morbidity and mortality are recognized consequences of rheumatoid arthritis (RA). In addition to chronic inflammation, reduced physical activity may contribute to adverse outcomes…
Abstract Number: 1576 • 2012 ACR/ARHP Annual Meeting
Identifying Subgroups of Rheumatoid Arthritis Patients Based On Levels of Pain, Disability, and Depression
Taylor Draper¹, Sarah R. Ormseth², M. Custodio³, Michael H. Weisman⁴, M.R. Irwin⁵ and Perry M. Nicassio⁵, ¹Psychology, Loma Linda University, Loma Linda, CA, ²Cousins Center for PNI, University of California, Los Angeles, Los Angeles, CA, ³UCLA, Los Angeles, CA, ⁴Cedars-Sinai Medical Center, Los Angeles, CA, ⁵Cousins Center for PNI, UCLA, Los Angeles, CA
Background/Purpose: Pain, disability, and depression are present in various degrees in patients with Rheumatoid Arthritis (RA). In spite of meeting the same diagnostic criteria, some…
Abstract Number: 1537 • 2012 ACR/ARHP Annual Meeting
Pathogenesis of Atherosclerosis in Granulomatosis Polyangiitis
Rula Hajj-Ali¹, Roy L. Silverstein², Gary S. Hoffman³ and Carol A. Langford⁴, ¹Cleveland Clinic Foundation, Cleveland, OH, ²Blood Research Institute, Medical College of Wisconsin, Milwaukee, WI, ³Rheumatic & Immunologic Dis, Cleveland Clinic Found A50, Cleveland, OH, ⁴Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, OH
Background/Purpose: Previous studies from our group suggested that the inflammatory events that occur during relapses in patients with Granulomatosis with Polyangiitis (GPA, Wegener’s) may have…
Abstract Number: 1538 • 2012 ACR/ARHP Annual Meeting
ANCA-Associated Vasculitis in Hispanic Americans: An Unrecognized Severity
Ranadeep Mandhadi¹, Fadi Aldaghlawi², Asad Khan², Vajiha Irshad³, Joel A. Block² and Antoine Sreih⁴, ¹Mount Sinai Hospital, Chicago, IL, ²Rush University Medical Center, Chicago, IL, ³Internal Medicine, Stroger Hospital of Cook County, Chicago, IL, ⁴Medicine/Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: ANCA-associated vasculitis, once a disease thought to predominate in Caucasians, is now increasingly recognized in diverse ethnic populations. However, there has been little systematic…
Abstract Number: 1539 • 2012 ACR/ARHP Annual Meeting
Microscopic Polyangiitis: A Large Single Center Series
Leslie D. Wilke¹, Guy P. Fiocco² and Marilyn Prince-Fiocco³, ¹Division of Pulmonary, Critical Care and Sleep Medicine, Scott & White Memorial Center, Temple, TX, ²Division of Rheumatology, Scott & White Clinic, Temple, TX, ³Temple, TX
Background/Purpose: Microscopic polyangiitis (MPA) is a rare systemic, ANCA (anti-neutrophil cytoplasmic antibody)-associated vasculitis of unclear etiology, characterized by necrotizing small vessel involvement with few or…
Abstract Number: 1540 • 2012 ACR/ARHP Annual Meeting
Practice Patterns in the Treatment of ANCA-Associated Vasculitis: Exploring Differences Among Subspecialties At a Single Academic Medical Center
Lindsy J. Forbess¹, Kenneth W. Griffin² and Robert F. Spiera³, ¹Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ²Public Health, Weill Cornell Medical College, New York, NY, ³Rheumatology, Hospital for Special Surgery, New York, NY
Background/Purpose: Randomized controlled trial evidence helps guide physician treatment choices for ANCA-Associated Vasculitis (AAV). Data for remission maintenance therapy following rituximab (RTX) in generalized disease,…
Abstract Number: 1541 • 2012 ACR/ARHP Annual Meeting
Does Leflunomide Have a Place As Remission Maintenance Therapy in ANCA-Associated Vasculitis? A Bayesian Network Meta-Analysis with Hypothesis Driven Sensitivity Analyses to Adjust for Potential Biases
Glen S. Hazlewood¹, Claudia Metzler², George A. Tomlinson³, Wolfgang L. Gross⁴, Brian M. Feldman⁵, Loic Guillevin⁶ and Christian Pagnoux⁷, ¹Medicine, University of Toronto, Toronto, ON, Canada, ²University of Lubeck, Bad Branstedy, Germany, ³University of Toronto, Toronto, ON, Canada, ⁴Dept of Clinical Rheumatology, Medical University at Lubeck, Lubeck, Germany, ⁵Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ⁶Internal Medicine, Cochin University Hospital, Paris, France, ⁷Rheumatology, Mount Sinai Hospital, Toronto, Canada, Toronto, ON, Canada
Background/Purpose: Primary: To determine the relative treatment effects of maintenance therapy in adult patients with ANCA-associated vasculitis who have achieved remission, using a Bayesian network…
Abstract Number: 1542 • 2012 ACR/ARHP Annual Meeting
The Efficacy of Rituximab Vs Cyclophosphamide for Treatment of Renal Disease in ANCA-Associated Vasculitis: The RAVE Trial Geetha D, Fervenza FC for the RAVE-Itn Research Group
Duvuru Geetha¹ and Fernando Fervenza², ¹Nephrology, Johns Hopkins University, Baltimore, MD, ²Mayo Clinic, Rochester, MN
Background/Purpose: Rituximab (RTX) is non-inferior to cyclophosphamide (CYC) followed by azathioprine (AZA) for remission-induction in severe ANCA associated vasculitis (AAV) but details of outcomes among…
Abstract Number: 1543 • 2012 ACR/ARHP Annual Meeting
Rituximab for ANCA-Associated Vasculitis: A Meta-Analysis of Randomized Trials
Carolina Mejia¹ and Carlos J. Lozada², ¹Internal Medicine, Mount Sinai Medical Center, Miami, FL, ²Dept of Medicine/Rheumatology, University of Miami Miller School of Medicine, Miami, FL
Background/Purpose: Over the past 40 years, cyclophosphamide/glucocorticoids combination therapy has been the standard regimen for remission induction in ANCA-associated vasculitis.. Although a major advance in…
Abstract Number: 1544 • 2012 ACR/ARHP Annual Meeting
Long-Term Outcome of Patients with Granulomatosis with Polyangiitis (Wegener’s) Treated with Rituximab
Lama Azar¹, Jason Springer², Meng Xu³, Tiffany M. Clark⁴, Carol A. Langford⁵ and Gary S. Hoffman⁴, ¹Rheumatic and Immunologic Diseases, Cleveland Clinic Foundation, Cleveland, OH, ²Dept of Rheumatology, Cleveland Clinic Foundation, Cleveland, OH, ³Section of biostatistics, Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH, ⁴Rheumatic & Immunologic Dis, Cleveland Clinic Foundation, Cleveland, OH, ⁵Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, OH
Background/Purpose: Rituximab (RTX) is an efficacious alternative to cyclophosphamide for treatment of granulomatosis with polyangiitis (GPA). However, relapses have been observed, long-term efficacy is not…
Abstract Number: 1545 • 2012 ACR/ARHP Annual Meeting
Long-Term Follow-up of 118 Polyarteritis Nodosa and Microscopic Polyangiitis without Poor-Prognosis Factors
Maxime Samson¹, Xavier Puechal², Hervé Devilliers³, Camillo Ribi⁴, Pascal Cohen⁵, Boris Bienvenu⁶, Christian Pagnoux⁷, Luc Mouthon⁸, Loic Guillevin⁹ and French Vasculitis Study Group FVSG¹⁰, ¹Department of Internal Medicine, Referral Center for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France; Internal Medicine and Clinical Immunology, Dijon University Hospital, Dijon, France, ²Internal Medicine, Hôpital Cochin, Paris, France, ³Internal medicine, Hôpital Général, Dijon, France, ⁴Internal Medicine, Hôpital Universitaire Cantonal de Genève, Geneve, Switzerland, ⁵National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, Paris, France, ⁶Division of Internal Medicine, Centre Hospitalier Régional Universitaire de Caen, Côte de Nacre, Caen, France, Caen, France, ⁷Rheumatology, Mount Sinai Hospital, Toronto, Canada, Toronto, ON, Canada, ⁸Internal Medicine, Hopital Cochim, Paris, France, ⁹Internal Medicine, Division of Internal Medicine, Hôpital Cochin, University Paris Descartes, Paris, France, ¹⁰Internal Medicine, Service de médecine interne, Centre de Références des Vascularites, Université Paris Descartes, APHP, Hôpital Cochin, 75005 Paris, France., Paris, France
Background/Purpose: Polyarteritis nodosa (PAN) and microscopic polyangiitis (MPA) are 2 vasculitides characterized by necrotizing inflammation of the vessel wall. They share several clinical features and…
Abstract Number: 1546 • 2012 ACR/ARHP Annual Meeting
Rhinosinusits and Nasal Polyps in the Diagnosis and Follow up of Patients with Eosinophilic Granulomatosis with Polyangitis (ex-Churg Strauss Syndrome)
Chiara Baldini¹, Veronica Seccia², Manuela Latorre³, Paolo Iannicelli², Daniela Martini¹, Francesco Ferro¹, Nicoletta Luciano¹, Antonio Tavoni⁴, Stefano Sellari Franceschini² and Stefano Bombardieri⁵, ¹University of Pisa, Rheumatology Unit, Pisa, Italy, ²Unit of Otorhinolaryngology, Department of Neuroscience, University of Pisa, Pisa, Italy, Pisa, Italy, ³University of Pisa, Pneumology Unit, Pisa, Italy, ⁴University of Pisa, Immunoallergology Unit, Pisa, Italy, ⁵Department of Clinical and Experimental Medicine, Rheumatology Unit, University of Pisa, Pisa, Italy
Background/Purpose: Chronic rhinosinusitis with nasal polyposis (CRSwP) is a common manifestation of granulomatosis with polyangitis (EGPA), and may represent an invalidating feature of the disease,…
Abstract Number: 1547 • 2012 ACR/ARHP Annual Meeting
A 4 Plus 2 Infusion Protocol of Rituximab Provides Long-Term Beneficial Effects in Patients with HCV-Associated Mixed Cryoglobulinemia with Membranoproliferative Nephritis and Severe Polyneuropathy
Dario Roccatello¹, Savino Sciascia², Simone Baldovino³ and Daniela Rossi¹, ¹Department of Rare, Immunologic, Hematologic and Immunohematologic Diseases, Centro di Immunopatologia e Documentazione su Malattie rare, Torino, Italy, ²Lupus Research Unit, The Rayne Institute, Kings College London School of Medicine, London, United Kingdom, ³Centro di Ricerche di Immunologia Clinica ed Immunopatologia e Documentazione su Malattie Rare (CMID), Università di Torino, Torino, Italy
Background/Purpose: Mixed cryoglobulinemia syndrome (MCs) is a systemic vasculitis characterized by multiple organ involvement due to the vascular deposition of immune-complexes, mainly the cryoglobulins. B…
Abstract Number: 1548 • 2012 ACR/ARHP Annual Meeting
Cutaneous Vasculitis as a Paraneoplastic Syndrome
Javier Loricera¹, Vanesa Calvo-Rio², Francisco Ortiz Sanjuan³, Marcos Antonio Gonzalez-Lopez⁴, Hector Fernandez-Llaca⁴, Javier Rueda-Gotor², Carmen Gonzalez-Vela⁵, Cristina Mata-Arnaiz³, Miguel A. Gonzalez-Gay² and Ricardo Blanco², ¹Rheumatology, Hospital Universitario Marqués de Valdecilla. IFIMAV. Santander. Spain, Santander, Spain, ²Rheumatology, Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, ³Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain, ⁴Dermatology, Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, ⁵Pathology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain
Background/Purpose: Cutaneous Leukocytoclastic Vasculitis (CLV) may be associated with malignancies, and sometimes it behaves as a paraneoplastic syndrome. This association has been reported in a…
Abstract Number: 1549 • 2012 ACR/ARHP Annual Meeting
Sibling Relative Risk and Heritability of Kawasaki Disease: A Nationwide Population Study in Taiwan
I-Jun Chou¹, Chang-Fu Kuo², Jing-Long Huang³, Chang-Teng Wu¹, Shao-Hsuan Hsia¹ and Hsiao-Chun Chang⁴, ¹Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ²Academic Rheumatology, School of Clinical Sciences, University of Nottingham, Nottingham, United Kingdom, ³Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ⁴Division of Rheumatology, Immunology and Allergy, Chang Gung Memorial Hospital, Taoyuan, Taiwan
Background/Purpose: Kawasaki disease (KD) is an autoimmune disease involving primarily medium-sized vessels and is the leading cause of acquired cardiac disease in children. The pathogenesis…

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