Abstracts Archive - Page 249 of 2425 - ACR Meeting Abstracts

Abstract Number: 1081 • ACR Convergence 2023
Clinical Consequences of Infliximab Immunogenicity and the Impact of Proactive Therapeutic Drug Monitoring: Secondary Analyses of a Randomised Clinical Trial
Marthe Brun¹, Kristin Hammersbøen Bjørlykke², Johanna E. Gehin³, David John Warren³, Rolf A. Klaasen³, Joseph Sexton¹, Øystein Sandanger⁴, Tore Kvien¹, Cato Mørk⁵, Jørgen Jahnsen², Nils Bolstad³, Kristin Kaasen Jørgensen², Espen Haavardsholm¹, Guro Goll¹ and Silje Watterdal Syversen¹, ¹Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway, ²Department of Gastroenterology, Akershus University Hospital, Oslo, Norway, ³Dept. of Medical Biochemistry, Oslo University Hospital, Oslo, Norway, ⁴Section of Dermatology, Oslo University Hospital, Oslo, Norway, ⁵Akershus Dermatology Center, Lørenskog, Norway
Background/Purpose: Formation of anti-drug antibodies (ADAb) to biological drugs is a clinical problem. Proactive therapeutic drug monitoring (TDM) allows for timely detection of ADAb and…
Abstract Number: 1257 • ACR Convergence 2023
The Psychological Experience of Work for People with Inflammatory Arthritis (IA)
Joan Westreich¹, Adena Batterman¹, Anna Balakrishnan¹, Roberta Horton¹, Minerva Nong¹, Vivian Bykerk² and Theodore Fields¹, ¹Hospital for Special Surgery, New York, NY, ²Department of Rheumatology, Hospital for Special Surgery, New York, NY
Background/Purpose: A large body of research reports that people with inflammatory arthritis (IA) are at increased risk for work disability, which profoundly affects all aspects…
Abstract Number: 1253 • ACR Convergence 2023
The Novel Florida Scoring System: A Machine Learning-Based Stratification of Clinical and Laboratory Features in Children with Suspected Sjögren’s Disease
Akaluck Thatayatikom¹, Wenjie Zeng², Tyler Lovelace³, Nicole Winn⁴, Ankit Shah⁵, Thomas Schrepfer⁶, Indraneel Bhattacharyya⁷, Renato Gonik⁸, Panayiotis Benos² and Seunghee Cha⁹, ¹AdventHealth for Children, Orlando, FL, Orlando, FL, ²University of Florida College of Public Health and Health Professions and College of Medicine, Gainesville, FL, ³Department of Computational & Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, ⁴Division of Oral Medicine, Department of Oral and Maxillofacial Diagnostic Sciences, University of Florida College of Dentistry, Gainesville, FL, ⁵Department of Ophthalmology, University of Florida College of Medicine, Gainesville, FL, ⁶Division of Pediatric Otolaryngology, University of Florida College of Medicine, Gainesville, FL, ⁷Department of Oral & Maxillofacial Diagnostic Sciences, University of Florida College of Dentistry, Gainesville, FL, ⁸Division of Pediatric Neurology, University of Florida College of Medicine, Gainesville, FL, ⁹Department of Oral & Maxillofacial Diagnostic Sciences, University of Florida College of Dentistry and Center for Orphaned Autoimmune Disorders (COAD), Gainesville, FL
Background/Purpose: Childhood Sjögren 's disease (cSjD) is a poorly defined systemic autoimmune disorder. Due to the absence of diagnostic criteria, heterogeneous presentations, and the dissimilarity…
Abstract Number: 0365 • ACR Convergence 2023
Establishing a Multidisciplinary Registry for Temporomandibular Joint Arthritis in Juvenile Idiopathic Arthritis: Insights into Patient Outcomes and Management Challenges
Stacey Tarvin¹, Amy Rakestraw², Jessica Lee², N. Shaun Matthews³, Susan H. Ballinger² and Christina M. Sparks², ¹Riley Hospital for Children at Indiana University Health, Indianapolis, IN, ²Indiana University School of Medicine, Indianapolis, IN, ³Indiana University School of Dentistry, Indianapolis, IN
Background/Purpose: Temporomandibular joint (TMJ) arthritis, a condition frequently overlooked in patients with JIA, can result in joint damage if not promptly treated. Such damage presents…
Abstract Number: 1263 • ACR Convergence 2023
Depression and Anxiety Risk Assessment in Patients with Rheumatic Diseases
Luis Vega Sevilla¹, Miguel Villarreal-Alarcon², Diana Paola Flores-Gutierrez³, Maria Corral-Trujillo⁴, Ricardo Juarez⁴, Ivan Hernandez Galarza⁵, Jesus Alberto Cardenas-De la Garza⁶ and Dionicio A. Galarza-Delgado², ¹Hospital Universitario UANL, Garcia, Mexico, ²Hospital Universitario UANL, Monterrey, Mexico, ³Hospital Universitario "Dr. José Eleuterio González", Monterrey, Mexico, ⁴Universidad Autónoma de Nuevo León, Monterrey, Mexico, ⁵University Hospital, UANL, San Pedro Garza Garcia, Mexico, ⁶Hospital Universitario "Dr. José Eleuterio González", San Nicolas, Mexico
Background/Purpose: Depression is one of the most common psychiatric comorbidities in patients with rheumatic diseases. A study has shown that almost a third of patients…
Abstract Number: 1097 • ACR Convergence 2023
Improving Vaccine Uptake of the Pneumococcal 20-valent Conjugate Vaccine (PCV20) in Young Rheumatic Disease Patients Using a Brief Intense Partnership Program
Kelsey Pasch¹, Stephen Lindsey² and Takeda Ferguson³, ¹Louisiana State University -- New Orleans, Baton Rouge, LA, ²LSU Health Science Center, New Orleans, LA, ³LSU Health Science Center School of Public Health, New Orleans, LA
Background/Purpose: Patients with inflammatory rheumatic diseases (IRDs) are at increased risk of infection. The Centers for Disease Control and Prevention (CDC) and the ACR strongly…
Abstract Number: 1130 • ACR Convergence 2023
Interobserver Reliability and Sensitivity to Change of a Composite Ocular Inflammatory Activity Index: UVEDAI
Esperanza Pato¹, Lara Borrego-Sanz², Marta Domínguez³, Fernando Alonso⁴, Fayna Rodríguez-Gonazález⁵, Marta Tejera-Santana⁵, María del Mar Esteban-Ortega⁶, Isabel García-Lozano⁷, Lucia Martinez-Costa⁸, Samuel Gonzalez-Ocampo⁸, Maite Sainz de la Maza⁹, Aina Moll-Udina⁹, Zulema Plaza¹⁰, Alejandro Fonollosa-Calduch¹¹, Joseba Artaraz¹¹, Teresa Díaz-Valle¹², María Gurrea-Almela¹², David Diaz-Valle¹³ and Rosalía Méndez-Fernández¹³, ¹Hospital Clínico San Carlos, Rheumatology, Madrid, Spain, ²Hospital Clinico San Carlos, Ophthalmology, Madrid, Spain, ³Sociedad Española de Reumatología, Madrid, Spain, ⁴Spanish Society of Rheumatology, Madrid, Spain, ⁵Hospital Doctor Negrín, Ophthalmology, Gran Canaria, Spain, ⁶Hospital Infanta Sofia, Madrid, Spain, ⁷Hospital Infanta Sofia, Ophthalmology, Madrid, Spain, ⁸Hospital Doctor Peset, Ophthalmology, Valencia, Spain, ⁹Hospital Clinic of Barcelona, Ophthalmology, Barcelona, Spain, ¹⁰Universidad Autónoma de Madrid, Madrid, Spain, ¹¹Hospital de Cruces, Ophthalmology, Bilbao, Spain, ¹²Hospital De Móstoles, Ophthalmology, Madrid, Spain, ¹³Hospital Clinico San Carlos, Madrid, Spain
Background/Purpose: Standardized and validated outcome measures of disease activity are lacking in the treatment and assessment of uveitis, making it difficult to compare efficacy and…
Abstract Number: 1146 • ACR Convergence 2023
Gene X Environment Paradigm: Exemplified by Selected Cases of Autoinflammatory Diseases
Qingping Yao and Peter Gorevic, Stony Brook University, Stony Brook, NY
Background/Purpose: The current scientific opinion holds that gene and environment (G X E) interactions contribute to certain human diseases. Systemic autoinflammatory diseases (SAIDs) are usually…
Abstract Number: 1265 • ACR Convergence 2023
Changes in the Endocannabinoid Tone in Rheumatoid Arthritis and Osteoarthritis – Discovery of a Novel Target for the Treatment of Pain and Inflammation?
Jost Klawitter¹, Andrew Clauw¹, Jennifer Seifert¹, Jelena Klawitter¹, Bridget Tompson¹, Cristina Sempio¹, Uwe Christians¹ and Larry Moreland², ¹University of Colorado Anschutz Medical Campus, Aurora, CO, ²University of Colorado, Denver, CO

Background/Purpose: Inflammation is a complicated physiological process that results in a variety of disorders. Several inflammatory mediators are produced during this process, which is responsible…
Abstract Number: 1161 • ACR Convergence 2023
Proteasome Inhibitor Repurposed for Dermatomyositis: Results of a Drug Repurposing Analysis Based on the Transcriptomic Signature of Patients’ Perifascicular Fibers Validated in Pre-clinical Models
Léa Debrut¹, Margherita Giannini², Céline Keime¹, Daniela Rovito¹, Béatrice Lannes³, Anne-Laure Charles⁴, Daniel Metzger¹, Bernard Geny⁵, Gilles Laverny¹ and Alain Meyer⁶, ¹Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France, ²Nouvel Hopital Civil, Strasbourg, Strasbourg, France, ³Hôpital de Hautepierre - Hôpitaux Universitaires de Strasbourg, Strasbourg, France, ⁴UR3072, Centre de Recherche en Biomédecine de Strasbourg (CRBS), Strasbourg, France, ⁵Nouvel Hôpital Civil, Strasbourg, France, ⁶Hôpitaux Universitaires de Strasbourg, Strasbourg, France
Background/Purpose: Dermatomyositis (DM) is an autoimmune myopathy responsible for muscle weakness associated with decreased quality of life and increased mortality. DM muscular histology is characterized…
Abstract Number: 0787 • ACR Convergence 2023
Understanding Distinct Resident and Migratory Fibroblast Populations in Systemic Sclerosis Skin Through Single-cell RNAseq and Immunohistochemistry
Kristina Clark¹, Shiwen Xu², Voon Ong³, Christopher Buckley⁴ and Christopher Denton², ¹Barts Health NHS Trust, London, United Kingdom, ²University College London, London, United Kingdom, ³UCL Medical School Royal Free Campus, London, United Kingdom, ⁴University of Oxford, Oxford, United Kingdom
Background/Purpose: We previously described distinct migratory and resident fibroblast populations from lesional skin biopsies in SSc patients. Both populations are profibrotic compared with those from…
Abstract Number: 1249 • ACR Convergence 2023
Cross-Sectional Associations of Emotional Distress and Cardiovascular Health in Juvenile Lupus and Dermatomyositis
Kaveh Ardalan¹, Angel Davalos¹, Hwanhee Hong¹, Bryce Reeve¹, Christoph Hornik¹, M. Anthony Moody¹, Donald Lloyd-Jones², Eveline Wu³, Audrey Ward¹, Rebecca Sadun⁴, Jeffrey Dvergsten⁵, Ann Reed⁶, Mark Connelly⁷ and Laura Schanberg¹, ¹Duke University School of Medicine, Durham, NC, ²Northwestern University Feinberg School of Medicine, Chicago, IL, ³University of North Carolina School of Medicine, Chapel Hill, NC, ⁴Duke University, Durham, NC, ⁵Duke University School of Medicine, Hillsborough, NC, ⁶Duke University School of Medicine, Chapel HIll, NC, ⁷Children's Mercy Kansas City / University of Missouri-Kansas City School of Medicine, Kansas City, MO
Background/Purpose: Juvenile lupus (JSLE) and dermatomyositis (JDM) patients are at high risk for cardiovascular disease (CVD). The American Heart Association cardiovascular health (CVH) construct is…
Abstract Number: 0364 • ACR Convergence 2023
Sex Differences in Clinical and Imaging Characteristics of Axial Juvenile Spondyloarthritis
Adam Mayer¹, Timothy G. Brandon², Pamela F. Weiss³ and on behalf of the JAXSPERT members², ¹University of Pennsylvania/Children's Hospital of Philadelphia, Philadelphia, PA, ²Children's Hospital of Philadelphia, Philadelphia, PA, ³Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: The extent to which heterogeneity exists in youth with axial disease and juvenile spondyloarthritis (JSpA) is unclear. In a cross-sectional sample of patients classified…
Abstract Number: 1245 • ACR Convergence 2023
Evaluating a Diagnostic Algorithm for Childhood Sjögren’s Disease
Sara Stern¹, Matthew Basiaga², Linda Amoafo¹, Seunghee Cha³, Akaluck Thatayatikom⁴, Erin Treemarcki¹, Rachel Randell⁵, Brian Dizon⁶, Jamie Diianni⁷, Sharon Tiger⁸, Janet Orrock⁹, Simone Appenzeller¹⁰, Cuoghi Edens¹¹ and Scott Lieberman¹², ¹University of Utah School of Medicine, Salt Lake City, UT, ²Mayo Clinic, Rochester, MN, ³Department of Oral & Maxillofacial Diagnostic Sciences, University of Florida College of Dentistry and Center for Orphaned Autoimmune Disorders (COAD), Gainesville, FL, ⁴AdventHealth for Children, Orlando, FL, Orlando, FL, ⁵Duke University School of Medicine, Durham, NC, ⁶National Institute of Arthritis and Musculoskelatal and Skin Diseases, Bethesda, MD, ⁷Childhood Arthritis and Rheumatology Research Alliance (CARRA), Washington, DC, ⁸Childhood Arthritis and Rheumatology Research Alliance (CARRA), Beltsville, MD, ⁹The University of Texas at Austin Dell Medical School, Austin, TX, ¹⁰UNICAMP, Campinas, Brazil, ¹¹University of Chicago, Chicago, IL, ¹²University of Iowa Carver College of Medicine, Iowa City, IA
Background/Purpose: There are no widely accepted diagnostic or classification criteria for childhood Sjögren's disease (cSjD). To address the urgent need for consensus, the Childhood Arthritis…
Abstract Number: 1105 • ACR Convergence 2023
Effects of Uric Acid Lowering Treatment on Vascular Stiffness in Gout Patients
Jinseok kim, Division of Rheumatology, Department of Internal Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, South Korea
Background/Purpose: Many studies have reported that gout and hyperuricemia are associated with an increase in all-cause mortality and cardiovascular mortality.Increased vascular stiffness is closely related…

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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