ACR Meeting Abstracts

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  • Abstract Number: 2059 • 2012 ACR/ARHP Annual Meeting

    The Efficacy of Clinical Guidelines in Promoting Co-Prescription of Bone Protection with Glucocorticoids Among Hospital Doctors Treating Inpatients

    Leonard C. Harty1, James Clare2, Dylan Finnerty2, Susan Van Der Kamp2, Fionnuala Kennedy3, Malachi McKenna4 and Oliver M. FitzGerald1, 1Rheumatology, Dublin Academic Medical Centre, St. Vincent's University Hospital, Dublin, Ireland, 2Department of Rheumatology, St. Vincent's University Hospital, Dublin, Ireland, 3Pharmacy Department, St. Vincent's University Hospital, Dublin, Ireland, 4Department of Endocrinology & Metabolic Bone Disease, St. Vincent's University Hospital, Dublin, Ireland

    Background/Purpose:  Therapeutic glucocorticoids (GC) rapidly decrease bone mineral density, inducing a remodelling imbalance by promoting osteoclast differentiation and activation and by inhibiting oscteocytes. Current guidelines…
  • Abstract Number: 2060 • 2012 ACR/ARHP Annual Meeting

    Using the Electronic Medical Record to Increase Rates of Physician Assessment of Lipids in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis: A Quality Improvement Initiative

    Astrud Lorraine Leyva1, Laura L. Tarter1, Elizabeth Blair Solow2 and David R. Karp3, 1Division of Rheumatic Diseases, UT Southwestern Medical Center, Dallas, TX, 2Rheumatology, UT Southwestern Medical Center, Dallas, TX, 3Rheumatic Diseases Division, UT Southwestern Medical Center, Dallas, TX

    Background/Purpose: Cardiovascular disease (CVD) is a major cause of morbidity and mortality in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Guidelines for the management…
  • Abstract Number: 2020 • 2012 ACR/ARHP Annual Meeting

    Assessment of Procedure Safety and Cannula Position in Temporomandibular Joint Puncture Evaluated by Cone Beam Computerized Tomography

    Thomas K. Pedersen1, Kasper D. Kristensen1, Per Alstergren2, Peter Stoustrup3, Annelise Küseler1 and Troels Herlin4, 1Department of Orthodontics, University of Aarhus, Aarhus C, Denmark, 2Department of Orofacial Pain and Jaw Function Faculty of Odontology, Malmö University, Malmö, Sweden, 3Section of Orthodontics, University of Aarhus, Aarhus C, Denmark, 4Pediatric Rheumatology Clinic, Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark

    Background/Purpose: Temporomandibular joint (TMJ) arthritis frequently occurs in juvenile idiopathic arthritis (JIA). Only sparse information is available concerning the inflammatory activity and the underlying biology…
  • Abstract Number: 2021 • 2012 ACR/ARHP Annual Meeting

    The Schedule of Administration of Canakinumab in Cryopyrin Associated Periodic Syndrome Is Driven by the Phenotype Severity Rather Than the Age

    Roberta Caorsi1, Loredana Lepore2, Francesco Zulian3, Maria Alessio4, Achille Stabile5, Antonella Insalaco6, Martina Finetti1, Antonella Battagliese4, Giorgia Martini7, Chiara Bibalo8, Alberto Martini9 and Marco Gattorno1, 1Second Division of Paediatrics, G. Gaslini Institute, Genova, Italy, 2Istituto Burlo Garofolo, Trieste, Italy, 3Department of Pediatrics, University of Padua, Padova, Italy, 4Department of Pediatrics,, Federico II Hospital, Napoli, Italy, 5DipartimentoPediatria, Policlinico Gemelli, Roma, Italy, 6Department of Pediatric Rheumatology, Ospedale Pediatrico Bambino Gesù, Roma, Italy, 7Department of Pediatrics,, University of Padua, Padua, Italy, 8Pediatrics-Univ of Trieste, Ospedale-Infantile Trieste, Trieste, Italy, 9Pediatric Rheumatology Collaborative Study Group [PRSCG], Cincinnati, OH

    Background/Purpose: to identify the optimal regimen for the treatment with Canakinumab in CAPS patients and, in patients receiving both Anakinra and Canakinumab during their disease…
  • Abstract Number: 2022 • 2012 ACR/ARHP Annual Meeting

    Individual Disease Burden in Children and Adolescents with Chronic Musculoskeletal Pain – Multilevel-Analysis of a Nationwide Prospective Longitudinal Observation Study

    Kerstin Gerhold1, Rebecca Muckelbauer2, Jacqueline Müller-Nordhorn2, Angelika Thon3, Thomas Müller4, Gerd Ganser5, Martina Niewerth6 and Kirsten Minden7, 1Programme Area Epidemiology, German Rheumatism Research Center, a Leipniz Institute, Berlin, Germany, 2Berlin School of Public Health, Charité - Universitätsmedizin Berlin, Berlin, Germany, 3Kinderklinik der Medizinischen Hochschule Hannover, Hannover, Germany, 4Universitätsklinikum Halle (Saale), Halle (Saale), Germany, 5Pediatric Rheumatology, Sankt Josef Stift, Sendenhorst, Germany, 6Epidemiology unit, German Rheumatism Research Center, Berlin, Germany, 7Programme Area Epidemiology, German Rheumatism Research Center, a Leibniz Institute, Berlin, Germany

    Background/Purpose: Chronic musculoskeletal pain was described to be a frequent complaint in children and adolescents with assumed relevant impairment of health-related quality of life (HRQoL)…
  • Abstract Number: 2023 • 2012 ACR/ARHP Annual Meeting

    Should Joint Ultrasound Contribute to Therapeutic Decisions in Juvenile Idiopathic Arthritis?

    Marie Halbwachs1, Geraldine Durand2, Caroline Robin1, Catherine Gambert Abdel Rahman1, Pierre Ingrand3 and Elisabeth Solau-Gervais2, 1Paediatric, University Hospital, Poitiers, France, 2Rheumatology, University Hospital, Poitiers, France, 3Inserm, CIC-P 802, University Hospital, Poitiers, France

    Background/Purpose: Over several years, numerous studies have been published on the interest of joint ultrasound in juvenile idiopathic arthritis. Several authors have demonstrated that ultrasonography…
  • Abstract Number: 2024 • 2012 ACR/ARHP Annual Meeting

    Articular Symptoms in Cryopyrin-Associated Periodic Syndrome: Retrospective French Study

    Laetitia Houx1, Pierre Quartier2, Isabelle Kone-Paut3, Xavier Guennoc4, Pascal Pillet5, Thierry Lequerre6, Irene Lemelle7, Mohamed Hamidou8, Gilles Grateau9, Eric Hachulla10, Jean-Marie Berthelot11, Benedicte Neven12, Christophe Richez13, Anne Pagnier14, Veronique Hentgen15 and Valerie Devauchelle-Pensec16, 1Physical Medical Rehabilitation, Brest, France, 2Necker-Enfants Malades Hospital,, Paris, France, 3Pediatrics, Hospital Kremlin Bicêre, Kremlin-Bicêtre, France, 4Rheumatology, Hopital de Saint Brieuc, France, 5Paediatry, CHU, Bordeaux, France, 6Rheumatology, Rouen, France, 7Paediatry, CHU, Nancy, France, 8Internal Medicine Department, Nantes University Hospital, Nantes, France, 9Service De Médecine Interne, Hopital Tenon, Paris, France, 10Department of Internal Medicine, Claude Huriez University Hospital, Lille, France, 11Rheumatology Unit, Nantes University Hospital, Nantes, France, 12Inserm U768, Paris, France, 13Rheumatology, Hôpital Pellegrin and Université Victor Segalen Bordeaux, Bordeaux, France, 14Service de pediatrie, Grenoble, France, 15Versailles Hospital, Le Chesnay Cedex, France, 16Department of rheumatology and unit of immunology (EA2216), Brest Occidentale university, Brest, France

    Background/Purpose: The cryopyrin-associated periodic syndrome (CAPS) is a rare inherited inflammatory disease associated with a mutation in the NLRP3 gene. Articular symptoms are often described…
  • Abstract Number: 2025 • 2012 ACR/ARHP Annual Meeting

    Clinical Characteristics and Therapy Response in a Large Single-Centre Cohort of Patients with Periodic Fever with Aphtous Stomatitis, Pharyngitis and Cervical Adenitis Syndrome

    Francesca Ricci1, Antonella Meini1, Lucio Verdoni2, Laura Dotta1, Marta Bolis2, Marco Berlucchi3, Gianfranco Savoldi4 and Marco Cattalini2, 1Pediatric Clinic, University of Brescia and Spedali Civili di Brescia, Pediatric Immunology and Rheumatology Unit, Brescia, Italy, 2Pediatric Clinic, Spedali Civili di Brescia and University of Brescia, Pediatric Immunology and Rheumatology Unit, Brescia, Italy, 3Spedali Civili di Brescia, Department of Pediatric Otorhinolaryngology, Brescia, Italy, 4Spedali Civili di Brescia, Angelo Nocivelli Institute of Molecular Medicine, Brescia, Italy

    Background/Purpose: PFAPA (Period Fever with Aphtous stomatitis, Pharyngitis and cervical Adenitis), is a periodic syndrome described for the first time in 1987 by Marshall et…
  • Abstract Number: 2026 • 2012 ACR/ARHP Annual Meeting

    High Prevalence of Cervical Spine and Temporomandibular Joint Involvement in Patients with Juvenile Idiopathic Arthritis

    Nikolay Tzaribachev1, Catrin Tzaribachev1 and Bernd Koos2, 1Pediatric Rheumatology, Center for Rheumatic Diseases, Bad Bramstedt, Germany, 2Clinic of Orthodontics, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany

    Background/Purpose:   Detection of involvement of temporomandibular joints (TMJ), which are frequently affected by juvenile idiopathic arthritis (JIA), is only possible on Gadolinium enhanced MRI…
  • Abstract Number: 2027 • 2012 ACR/ARHP Annual Meeting

    Chronic Nonbacterial Osteomyelitis of the Mandible in Children: a Tertiary Center Experience

    Daniela S. Ardelean1 and Ronald Laxer2, 1Pediatric Rheumatology, Hospital for Sick Children, Toronto, ON, Canada, 2Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada

    Background/Purpose:  Chronic nonbacterial osteomyelitis (CNO) of the mandible is a rare osseous autoinflammatory disease. Diagnosis is based on characteristic clinical, laboratory and imaging features. Our…
  • Abstract Number: 2028 • 2012 ACR/ARHP Annual Meeting

    Medication Adherence and Quality of Life in Children with Rheumatic Disease

    Stacey E. Tarvin1, Lisa M. Macharoni2, Christine M. Raches3 and Nicole M. Taylor2, 1Pediatric Rheumatology, Riley Hospital for Children, Indianapolis, IN, 2School of Psychological Sciences, University of Indianapolis, Indianapolis, IN, 3Riley Child Development Center, Riley Hospital for Children, Indianapolis, IN

    Background/Purpose: Children with rheumatic diseases are often prescribed complex medication regimens.  Medication side-effects may have a negative impact on physical appearance and subsequently impact adherence. …
  • Abstract Number: 2029 • 2012 ACR/ARHP Annual Meeting

    Reliability of Scoring a Disease Damage Measure for Juvenile Localized Scleroderma

    Kathryn S. Torok1, Suzanne C. Li2, Christina Kelsey3, Mara L Becker4, Fatma Dedeoglu5, Robert C. Fuhlbrigge6, Gloria Higgins7, Sandy D. Hong8, Maria F. Ibarra9, Ronald Laxer10, Thomas G. Mason II11, Marilynn G. Punaro12, Elena Pope13, C. Egla Rabinovich14 and Katie G. Stewart12, 1Pediatric Rheumatology, Scleroderma Center of Pittsburgh, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, 2Pediatrics, Joseph M Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack, NJ, 3Pediatric Rheumatology, Univ of Pittsburgh Med Ctr, Pittsburgh, PA, 4Clinical Pharmacology and Rheumatology, Children's Mercy Hospital, Kansas City, MO, 5Division of Immunology, Boston Children's Hospital, Boston, MA, 6Pediatric Rheumatology, Childrens Hospital, Boston, MA, 7Pediatric Rheumatology NATIONWIDE CHILDRENS HOSPITAL, PRCSG-Cincinnati Children's Hospital Medical Center, Columbus, OH, 8Pediatrics-Rheumatology, U of Iowa Children's Hosp, Iowa City, IA, 9Pediatric Rheumatolgy, Children's Mercy Hospital, Kansas City, MO, 10Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 11Rheumatology, Mayo Clinic Rochester, Rochester, MN, 12Pediatric Rheumatology, Texas Scottish Rite Hospital, Dallas, TX, 13Dermatology, The Hospital for Sick Children, Toronto, ON, Canada, 14Pediatric Rheumatology, Duke University Medical Center, Durham, NC

    Background/Purpose: .    In order to more accurately capture disease activity and damage in juvenile Localized Scleroderma (jLS) and to develop an accepted outcome measure for…
  • Abstract Number: 2030 • 2012 ACR/ARHP Annual Meeting

    A Multi-Modal Amplified Musculoskeletal Pain Treatment Program: Associations of Previous Pharmacotherapy with Subsequent Outcomes

    Cara M. Hoffart1, Pamela Weiss2, David D. Sherry3, Chris Feudtner4 and Margaret Stineman5, 1The Children's Hospital of Philadelphia, Philadelphia, PA, 2Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA, 3Pediatric Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, 4Division of General Pediatrics, Children's Hospital of Philadelphia; University of Pennsylvania Center for Clinical Epidemiology and Biostatistics, Philadelphia, PA, 5The University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Management of Amplified Musculoskeletal Pain (AMP) in children (i.e. juvenile primary fibromyalgia, complex regional pain syndrome, neuropathic pain, central sensitization) remains controversial. Common practice…
  • Abstract Number: 2031 • 2012 ACR/ARHP Annual Meeting

    Safety and Efficacy of Anakinra in Patients with Deficiency of Interleukin-1 Receptor Antagonist

    Gina A. Montealegre1, Adriana Almeida de Jesus2, Dawn C. Chapelle3, Paul Dancey4, Joost Frenkel5, Annet van Royen-Kerkhoff6, Ronit Herzog7, Giovanna Ciocca8, Rafael F. Rivas-Chacon8, Ann M. Reed9, Nicole Plass3, Ivona Aksentijevich10, Polly J. Ferguson11, Suvimol C. Hill12, Edward Cowen13 and Raphaela T. Goldbach-Mansky3, 1NIAMS, Bethesda, MD, 2Translational Autoinflammatory Disease Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD, 3Translational Autoinflammatory Diseases Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD, 4Health Science Centre, Memorial University of Newfoundland, St Johns, Canada, 5Wilhelmina Childrens Hospital, University of Utrecht, Utrecht, Netherlands, 6University of Utrecht, Utrecht, Netherlands, 7Cornell University, New York, NY, 8Miami Children's Hospital, Miami, FL, 9Rheumatology, Mayo Clinic, Rochester, MN, 10Inflammatory Disease Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 11Dept of Pediatrics--Rheum, University of Iowa Carver College of Medicine, Iowa City, IA, 12Radiology and Imaging Sciences, NIH Clinical Center, Bethesda, MD, 13Dermatology Consultation Servce, National Cancer Institute, National Institutes of Health, Bethesda, MD

    Background/Purpose: Deficiency of interleukin-1 receptor antagonist (DIRA) is a neonatal-onset autoinflammatory syndrome caused by mutations in IL1RN gene and clinically characterized by a perinatal onset…
  • Abstract Number: 2032 • 2012 ACR/ARHP Annual Meeting

    Results From a Multicentre International Registry of Familial Mediterranean Fever: Impact of Genetic and Environment Factors On the Expression of a Monogenic Disease in Children

    Seza Ozen1, Erkan Demirkaya2, Gayane Amaryan3, Isabelle Koné-Paut3, Adem Polat3, Turker Turker3, Patricia Woo4, Yosef Uziel5, Consuelo Modesto3, Martina Finetti3, Pierre Quartier6, Efimia Papadopoulou-Alataki3, Sulaiman Al-Mayouf3, Giovanna Fabio3, Romina Gallizzi7, Luca Cantarini8, Joost Frenkel9, Susan Nielsen10, Michael Hofer3, Antonella Insalaco3, Huri Ozdogan3, Nicolino Ruperto3 and Marco Gattorno3, 1Hacettepe University, Ankara, Turkey, 2Gulhane Military Medical Faculty, Ankara, Turkey, 3Paediatric Rheumatology International Trials Organization (PRINTO), Istituto Giannina Gaslini, Genova, Italy, 4University College London, London, United Kingdom, 5Pediatric Rheumatology, Meir medical center, Kfar Saba, Israel, 6Pediatric Rheumatology, IMAGINE Institute, Hôpital Necker-Enfants Malades, Assistance Publique Hôpitaux de Paris, Université Paris-Descartes, Paris, France, 7University of Messina, Messina, Italy, 8University of Siena, Siena, Italy, 9University Medical Center Utrecht, Utrecht, Netherlands, 10Istituto Giannina Gaslini, Genoa, Italy

    Background/Purpose: Familial Mediterranean Fever (FMF) is an autoinflammatory disease caused by mutations in a single gene, the MEFV gene. The disease is very frequent among…
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