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  • Abstract Number: 2662 • 2012 ACR/ARHP Annual Meeting

    Tightening up: Musculoskeletal Ultrasound Could Further Individualise Treatment Decisions in Early Rheumatoid Arthritis Patients Treated by a Step-up DMARD Escalation Regimen

    James Dale1, David Purves2, Alex McConnachie2, Duncan Porter3 and Iain B. McInnes4, 1Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom, 2Robertson Centre for Biostatistics, University of Glasgow, Glasgow, United Kingdom, 3Rheumatology, Gartnavel General Hospital, Glasgow, United Kingdom, 4Glasgow Biomedical Research Centre, University of Glasgow, Glasgow, United Kingdom

    Background/Purpose: Treat-to-target (T2T) strategies have significantly improved outcomes in early rheumatoid arthritis (RA). Treatment escalation is usually guided by a disease activity score; however, modern…
  • Abstract Number: 2663 • 2012 ACR/ARHP Annual Meeting

    A Variant in the Osteoprotegerin Gene Is Associated with Coronary Atherosclerosis in Patients with Rheumatoid Arthritis: Results From a Candidate Gene Study

    Cecilia P. Chung1, Joseph F. Solus2, Annette M. Oeser3, Chun Li4, Paolo Raggi5, Jeffrey R. Smith3 and C. Michael Stein3, 1Medicine, Vanderbilt University, Nashville, TN, 2Medicine, Vanderbilt Medical Center, Nashville, TN, 3Vanderbilt University, Nashville, TN, 4Biostatistics, Vanderbilt University, Nashville, TN, 5Emory University, Atlanta, GA

    Background/Purpose: Patients with rheumatoid arthritis (RA) have accelerated atherosclerosis. However, this association is not fully explained by traditional cardiovascular risk factors or markers of inflammation. Little is…
  • Abstract Number: 2664 • 2012 ACR/ARHP Annual Meeting

    A Multi-Biomarker Disease Activity (VECTRA™ DA Algorithm) Score Reflects Clinical Disease Activity and Tracks Responses in Patients with Rheumatoid Arthritis Treated with Either Adalimumab, Etanercept, and Infliximab

    Shintaro Hirata1, Douglas J. Haney2, Guy Cavet2, Rebecca Bolce2, Wanying Li2, Nadine Defranoux2, David Chernoff2, Kunihiro Yamaoka1, Kazuyoshi Saito1 and Yoshiya Tanaka1, 1The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan, 2Crescendo Bioscience Inc., South San Francisco, CA

    Background/Purpose : Anti-TNF therapy has become a standard therapeutic strategy for treatment of patients with rheumatoid arthritis (RA).  A validated multi-biomarker disease activity algorithm (MBDA) blood…
  • Abstract Number: 2665 • 2012 ACR/ARHP Annual Meeting

    Metabolic Reprogramming of Autoimmune T Cells in Rheumatoid Arthritis

    Zhen Yang1, Hiroshi Fujii2, Shalini Mohan1, Jorg J. Goronzy1 and Cornelia M. Weyand3, 1Medicine: Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, 2Department of Hematology and Rheumatology, Tohoku University, Sendai, Japan, 3Medicine, Stanford University School of Medicine, Stanford, CA

    Background/Purpose: In RA, autoimmunity precedes clinical symptoms by a decade and persists unabated even when downstream inflammation is well controlled; exposing lymphocytes to chronic stimulation…
  • Abstract Number: 2626 • 2012 ACR/ARHP Annual Meeting

    The Utility of the Patient Health Questionnaire-9 to Assess Suicide Risk in Patients with Systemic Sclerosis

    Ilya Razykov1, Marie Hudson2, Murray Baron3 and Brett D. Thombs1, 1Psychiatry, McGill University, Montreal, QC, Canada, 2Jewish General Hospital, McGill University, Montreal, QC, Canada, 3Pavillion A, Rm 216, Lady David Institute for Medical Research and Jewish General Hospital, Montreal, QC, Canada

    Background/Purpose: Depression is common in rheumatic diseases, including systemic sclerosis (SSc). In the general population, depression is associated with suicidal ideation, attempts and completion. The…
  • Abstract Number: 2627 • 2012 ACR/ARHP Annual Meeting

    Gender Differences of Concepts Important to People Living with Crohn’s Disease and Their Coverage by Commonly Used Patient-Reported Outcome Instruments: Patient’s Perspective Elevated by a Qualitative Study

    Mona Dür1, Michaela Coenen2, Josef S. Smolen3, Clemens Dejaco4 and Tanja A. Stamm5, 1Internal Medicine III Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 2Department of Medical lnformatics, Biometry and Epidemiology, Research Unit for Biopsychosocial Health, Ludwig-Maximilians-University, Munich, Germany, 3Division of Rheumatology, Department of Internal Medicine III,, Medical University of Vienna and Hietzing Hospital, Vienna, Austria, 4Internal Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria, 5Rheumatology, Medical University of Vienna, Vienna, Austria

    Background/Purpose: Crohn's disease (CD) has a major impact on functioning, health and well-being and patient-reported outcome (PRO) instruments have not been analysed from the perspective…
  • Abstract Number: 2628 • 2012 ACR/ARHP Annual Meeting

    The Lumbo-Pelvic Muscles and Axial Spondyloarthritis: A Pilot Observational Study

    Janet Millner1, Julie A. Hides2, Patricia Lewis3 and Jane Zochling3, 1Physiotherapy, Royal Hobart Hospital, Hobart, Australia, 2School of Physiotherapy, Australian Catholic University, Brisbane, Australia, 3Menzies Research Institute Tasmania, Hobart, Australia

    Background/Purpose: The importance of a physical approach in the management of axial spondyloarthritis (SpA) has been recognised for many years. It is supported by level…
  • Abstract Number: 2629 • 2012 ACR/ARHP Annual Meeting

    Associations of Current and Early-Life Socioeconomic Positions with Risk of Self-Reported Doctor-Diagnosed Arthritis in a Family-Medicine Cohort of North-Carolinians

    Antoine A. Baldassari1, Rebecca J. Cleveland1 and Leigh F. Callahan2, 1Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2Thurston Arthritis Res Ctr, University of North Carolina, Chapel Hill, NC

    Background/Purpose: Socioeconomic position (SEP) across the lifecourse has been convincingly identified as a determinant of health. In particular, mounting evidence suggests that low current and…
  • Abstract Number: 2630 • 2012 ACR/ARHP Annual Meeting

    Rheumatoid Arthritis and Osteoarthritis in the Population: How Different Is the Impact?

    Christina H. Chan1, Mayilee Canizares2 and E.M. Badley3, 1Division of Healthcare Outcomes and Research, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada, 2Division of Healthcare Outcomes and Research, Toronto Western Research Institute, Toronto, ON, Canada, 3Division of Health Care and Outcomes Research, Toronto Western Research Institute; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada

    Background/Purpose: It is a common perception that rheumatoid arthritis (RA) is a more severe and debilitating disease than osteoarthritis (OA); however, there have been many…
  • Abstract Number: 2631 • 2012 ACR/ARHP Annual Meeting

    Radiographic Osteoarthritis Severity Is Associated with an Increased Risk of Developing Knee Pain: Findings From the Osteoarthritis Initiative

    Jingbo Niu1, David T. Felson2, Tuhina Neogi3 and Yuqing Zhang4, 1Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 2Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, 3Clinical Epidemiology, Boston Univ School of Medicine, Boston, MA, 4School of Medicine, Boston Univ School of Medicine, Boston, MA

    Background/Purpose : While knee pain is a major complaint from subjects with knee osteoarthritis (OA), most epidemiologic studies have found only weak to moderate associations…
  • Abstract Number: 2632 • 2012 ACR/ARHP Annual Meeting

    Doing Is Believing: Health Beliefs Before and After an Exercised-Based Rehabilitation Programme for Chronic Knee Pain

    Mike Hurley1 and Dr Nicola E. Walsh2, 1School of Rehabilitation Sciences, St George's University of London, London, United Kingdom, 2Allied Health Professions, University of the West of England Bristol, Bristol, United Kingdom

    Background/Purpose: An integrated exercise-based rehabilitation programme, Enabling Self-management and Coping with Arthritis knee Pain through Exercise (ESCAPE-knee pain), improves pain and physical disability of people…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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