Abstracts Archive - Page 2421 of 2607 - ACR Meeting Abstracts

Abstract Number: 89 • 2013 ACR/ARHP Annual Meeting
Meta-Analysis of Randomized Controlled Trials Assessing the Effects of Vitamin D Supplementation On Skeletal Muscle Strength
Charlotte Beaudart¹, Fanny Buckinx², Véronique Rabenda³, Sophie Gillain⁴, Etienne Cavalier⁵, Jean Petermans⁴, Jean-Yves Reginster⁶ and Olivier Bruyere¹, ¹Public Health/Epidemiology, University of Liege, Liege, Belgium, ²Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium, ³Public Health, Epidemiology and Health Economics, University of Liege, Liege, Belgium, ⁴Geriatric Department, CHU de Liege, Liege, Belgium, ⁵Department of Clinical Chemistry, CHU de Liege, Liege, Belgium, ⁶Department of Public Health, Epidemiology and Health Economics, University of Liege, Liege, Belgium
Background/Purpose: Currently, there is growing evidence that vitamin D plays a role on several tissues including skeletal muscle. Previous studies suggested that vitamin D deficiency is…
Abstract Number: 90 • 2013 ACR/ARHP Annual Meeting
Insufficient Evidence For An Increase In Prevalence and Incidence Of Gout: A Systematic Review and Meta-Regression Analysis
José M.A. Wijnands¹, Wolfgang Viechtbauer², Kristof Thevissen³, Ilja C.W. Arts⁴, Pieter C. Dagnelie⁴, Coen D.A. Stehouwer⁵, Sjef van der Linden³ and Annelies Boonen³, ¹Department of Internal Medicine, Division of Rheumatology, Maastricht University, Maastricht, Netherlands, ²Department of Psychiatry and Psychology, Maastricht University, Maastricht, Netherlands, ³Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ⁴Department of Epidemiology, Maastricht University, Maastricht, Netherlands, ⁵Department of Internal Medicine, Maastricht University Medical Center, Maastricht, Netherlands
Background/Purpose: Estimates on the prevalence and incidence of gout in the general population vary widely and an increase is commonly reported. However, studies on the…
Abstract Number: 91 • 2013 ACR/ARHP Annual Meeting
Risk Factors For Incident Hyperuricemia During Mid-Adulthood In African American and White Men and Women Enrolled In The Atherosclerosis Risk In Communities Study
Mara McAdams DeMarco¹, Andrew Law², Janet W. Maynard³, Josef Coresh¹ and Alan N. Baer⁴, ¹Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, ²Epidemiology, Johns Hopkins, Baltimore, MD, ³Rheum/Mason F Lord Bldg/CtrTow, Johns Hopkins University School of Medicine, Division of Rheumatology, Baltimore, MD, ⁴Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose : Increased serum urate levels are associated with poor outcomes including but not limited to gout. Better understanding of which patients are at risk…
Abstract Number: 92 • 2013 ACR/ARHP Annual Meeting
Kidney Function and Alcohol Intake and The Risk Of Incident Gout In a Population-Based Cohort Of Adults: Atherosclerosis Risk In Communities Study
Mara McAdams DeMarco¹, Anna Kottgen², Andrew Law³, Janet W. Maynard⁴, Morgan Grams⁵, Josef Coresh¹ and Alan N. Baer⁶, ¹Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, ²Renal Division, University Hospital Freiburg, Freiburg, Germany, ³Epidemiology, Johns Hopkins, Baltimore, MD, ⁴Rheum/Mason F Lord Bldg/CtrTow, Johns Hopkins University School of Medicine, Division of Rheumatology, Baltimore, MD, ⁵Nephrology, Johns Hopkins, Baltimore, MD, ⁶Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose: Reduced kidney function is associated with higher urate levels as well as an increased risk of gout. Additionally, alcohol intake is known to increase…
Abstract Number: 93 • 2013 ACR/ARHP Annual Meeting
Higher Consumption Of Sugar-Sweetened Soft Drinks Increases The Risk Of Hyperuricemia In Korean Population: The Korean Multi-Rural Communities Cohort Study
Seong-Kyu Kim¹, Jisuk Bae², Jung-Yoon Choe¹, Byung-Yeol Chun³, Pil Sook Park⁴ and Dong Hoon Shin⁵, ¹Catholic University of Daegu School of Medicine, Daegu, South Korea, ²Department of Preventive Medicine, Catholic University of Daegu School of Medicine, Daegu, South Korea, ³Kyungpook National University School of Medicine, Daegu, South Korea, ⁴Kyungpook National University, Daegu, South Korea, ⁵School of Medicine Keimyung University, Daegu, South Korea
Background/Purpose: The aim of this study is to clarify the association between sugar-sweetened soft drinks and fruit drinks made from oranges and apples and the…
Abstract Number: 95 • 2013 ACR/ARHP Annual Meeting
Hip Osteoarthritis and Risk Of All Cause and Disease-Specific Mortality Among Older Women: A Population-Based Cohort Study
Kamil E. Barbour¹, Li-Yung Lui², Charles G. Helmick³, Kristina A. Theis⁴, Michael C. Nevitt⁵, Nancy E. Lane⁶, Louise Murphy¹, Jennifer M. Hootman⁷, Marc C. Hochberg⁸ and Jane A. Cauley⁹, ¹Centers for Disease Control and Prevention, Atlanta, GA, ²California Pacific Medical Center, San Francisco, CA, San Francisco, CA, ³National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, ⁴Athritis Program, Centers for Disease Control and Prevention, Atlanta, GA, ⁵Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, ⁶Internal Medicine, Center for Musculoskeletal Health, UC Davis School of Medicine, Sacramento, CA, ⁷Division of Population Health, Centers for Disease Control and Prevention, Kennesaw, GA, ⁸Medicine, University of Maryland School of Medicine, Baltimore, MD, ⁹Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: The morbidity of osteoarthritis (OA) is well documented; however few comprehensive studies have examined the effect of OA on mortality. Methods: We used data…
Abstract Number: 96 • 2013 ACR/ARHP Annual Meeting
Epidemiology and Health Services Use For Osteoarthritis By First Nations People In Alberta, Canada
Cheryl Barnabe¹, Allyson Jones², Ed Enns³, Don Voaklander⁴, Christine Peschken⁵, Joanne Homik⁴, John Esdaile⁶, Sasha Bernatsky⁷, Brenda Hemmelgarn⁸ and Deborah Marshall⁹, ¹Medicine, Community Health Sciences, University of Calgary, Calgary, AB, Canada, ²Department of Physical Therapy, University of Alberta, Edmonton, AB, Canada, ³Alberta Bone and Joint Health Institute, Calgary, AB, Canada, ⁴University of Alberta, Edmonton, AB, Canada, ⁵Medicine & Community Health Sciences, University of Manitoba, Winnipeg, MB, Canada, ⁶Medicine, University of British Columbia, Vancouver, BC, Canada, ⁷Clinical Epidemiology, Research Institute of the McGill University Health Ctre, Montreal, QC, Canada, ⁸Division of Nephrology, University of Calgary, Calgary, AB, Canada, ⁹University of Calgary, Calgary, AB, Canada
Background/Purpose: Self-reported survey data and a single provincial administrative data source have previously indicated that the First Nations (FN) population in Canada has a 1.5…
Abstract Number: 97 • 2013 ACR/ARHP Annual Meeting
Incidence and Trend Of Osteoarthritis In An Administrative Database From British Columbia, Canada
M Mushfiqur Rahman^1,2, Jolanda Cibere^3,4, Charles H Goldsmith^2,5, Aslam H. Anis^6,7 and Jacek A. Kopec^1,8, ¹School of Population and Public Health, University of British Columbia, VANCOUVER, BC, Canada, ²Biostatistics, Arthritis Research Centre of Canada, Richmond, BC, Canada, ³Department of Medicine, University of British Columbia, VANCOUVER, BC, Canada, ⁴Division of Rheumatology, Arthritis Research Centre of Canada, Richmond, BC, Canada, ⁵Health Sciences, Simon Fraser University, Burnaby, BC, Canada, ⁶St. Paul's Hospital, Centre for Health Evaluation and Outcome Sciences, Vancouver, BC, Canada, ⁷School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada, ⁸Arthritis Research Centre of Canada, Richmond, BC, Canada
Background/Purpose: Data on the incidence of osteoarthritis (OA) are limited and there is little information on the trend in incidence of OA over time. The…
Abstract Number: 98 • 2013 ACR/ARHP Annual Meeting
Prevalence Of Femoroacetabular Impingement Among Chinese Living In Vancouver, Canada: A Population-Based Study
Linda C. Li¹, Jacek A. Kopec², Hubert Wong³, Jolanda Cibere⁴, Charlie Zhang⁵, Eric C. Sayre², Joanna Ye², Morgan Barber², Helen Prlic⁶ and John Esdaile⁷, ¹Physical Therapy, Arthritis Centre of Canada, Richmond, BC, Canada, ²Arthritis Research Centre of Canada, Richmond, BC, Canada, ³School of Population and Public Health, University of British Columbia, St Paul's Hospital, University of British Columbia, Vancouver, V6Z 1Y6, Canada, Vancouver, BC, Canada, ⁴Division of Rheumatology, Arthritis Research Centre of Canada, Richmond, BC, Canada, ⁵Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada, ⁶Arthritis Research Centre of Canada, Vancouver, BC, Canada, ⁷Rheumatology, Arthritis Research Centre of Canada, University of British Columbia, Richmond, BC, Canada
Background/Purpose: Femoroacetabular Impingement (FAI) is one source of hip pain in young adults and has been suggested as a major cause of hip osteoarthritis (OA).…
Abstract Number: 99 • 2013 ACR/ARHP Annual Meeting
Twenty-First Century Prevalence Of Frequent Knee Pain, Radiographic, Symptomatic and Clinical Knee Osteoarthritis According to American College Of Rheumatology Criteria In Southern Sweden
Aleksandra Turkiewicz¹, Maria Gerhardsson de Verdier², Gunnar Engström³, Stefan Lohmander¹ and Martin Englund¹, ¹Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden, ²Astra Zeneca R&D Molndal, Molndal, Sweden, Molndal, Sweden, ³Dept of Cardiovascular epidemiology, Clinical Sciences, Lund University, Lund, Sweden
Background/Purpose: To provide current estimates of the prevalence of knee pain, radiographic, symptomatic, and clinical knee osteoarthritis (OA) in middle-aged and elderly in Sweden. Methods:…
Abstract Number: 67 • 2013 ACR/ARHP Annual Meeting
Heparin-Binding Epidermal Growth Factor-Like Growth Factor (HB-EGF) As a Potential Mediator In Osteoarthritis
Richard F. Loeser¹ and David A. Long², ¹Section Of Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, ²Section Of Molecular Medicine, Wake Forest University, Winston-Salem, NC
Background/Purpose: We recently reported changes in gene expression in knee joint tissue from 12 week-old and 12 month-old mice after OA was induced by surgical…
Abstract Number: 60 • 2013 ACR/ARHP Annual Meeting
O-Linked N-Acetylglucosamine Modified Proteome Of Human Osteoarthritic Cartilage: Biological Significance
Jessica Andrés-Bergós^1,2, María Luisa Hernáez³, Miguel Otero², Ane Larranaga-Vera¹, Sandra Pérez-Baos¹, Mary B. Goldring², Gabriel Herrero-Beaumont¹ and Raquel Largo⁴, ¹Joint and Bone Research Unit. IIS-Fundación Jiménez Díaz. UAM, Madrid, Spain, ²Tissue Engineering Repair and Regeneration Program, Hospital for Special Surgery and Weill Cornell Medical College, New York, NY, ³Proteomics Unit, Universidad Complutense de Madrid-Parque Científico de Madrid, ProteoRed ISCIII, Madrid, Spain, ⁴Bone and Joint Research Unit, IIS-Fundación Jiménez Díaz, Madrid, Spain
Background/Purpose: O-linked N-acetylglucosamine (O-GlcNAc) post-translational modifications have been implicated in the control of different signaling cascades and in the development and progression of degenerative and…
Abstract Number: 61 • 2013 ACR/ARHP Annual Meeting
Epigenome-Wide DNA Methylation Study Reveals Hypermethylated Collagen Genes and Suggests a Role for TGFβ in Osteoarthritis
Matlock A. Jeffries^1,2, Amr H. Sawalha³ and Judith A. James⁴, ¹Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ²Arthritis & Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ³Division of Rheumatology, University of Michigan, Ann Arbor, MI, ⁴Oklahoma Medical Research Foundation, Oklahoma City, OK
Background/Purpose: Osteoarthritis (OA) is the leading cause of chronic disability in the U.S., affecting 40% of individuals over the age of 70 and costing $128…
Abstract Number: 62 • 2013 ACR/ARHP Annual Meeting
Tenogenic Effect Of Homeobox Mohawk gene for Bone Marrow Mesenchymal Stem Cells
Koji Otabe¹, Hiroyuki Nakahara¹, Akihiko Hasegawa¹, Martin K. Lotz¹ and Hiroshi Asahara², ¹Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, ²Molecular & Experimental Med, The Scripps Research Institute, La Jolla, CA
Background/Purpose: Mohawk homeobox (MKX) has been demonstrated as a tendon and ligament specific transcriptional factor. MKX knock-out mice showed hypoplastic tendons throughout the body, due…
Abstract Number: 63 • 2013 ACR/ARHP Annual Meeting
Investigations On The Role Of Delta/Notch Like EGF-Related Receptor In The Pathogenesis Of Osteoarthritis
Lucija Berninger¹, Anna Balkenhol¹, Clemens Baier², Stefan Rehart³, Markus Rickert⁴, Ulf Müller-Ladner¹, Elena Neumann⁵ and Matthias Geyer¹, ¹Internal Medicine and Rheumatology, Justus-Liebig-University of Gießen, Kerckhoff-Klinik, Bad Nauheim, Germany, ²Orthopaedic surgery, University of Regensburg, Bad Abbach, Germany, ³Orthopedics and Trauma Surgery, Markus-Hospital, Frankfurt, Germany, ⁴Dept of Orthopedics and Orthopedic Surgery, University Hospital Giessen and Marburg, Giessen, Germany, ⁵Department of Internal Medicine and Rheumatology, Justus-Liebig-University of Gießen, Kerckhoff-Klinik, Bad Nauheim, Germany
Background/Purpose: Delta/Notch like EGF-related receptor (DNER) is a single-pass transmembrane protein with characteristic EGF-like repeats in the extracellular domain, similar to those of the Notch…

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