ACR Meeting Abstracts

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  • Abstract Number: 70 • 2012 ACR/ARHP Annual Meeting

    The Impact of Systemic Autoimmune Rheumatic Disease On One-Year Mortality in Congestive Heart Failure Patients: A Population-Level Analysis

    Stephanie O. Keeling1, Asvina Bissonauth1, Becky Leung2 and Padmaja Kaul2, 1Medicine, University of Alberta, Edmonton, AB, Canada, 2Cardiology, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: Little is known about the prevalence of systemic autoimmune rheumatic diseases (SARDs) in patients with congestive heart failure (CHF) and its contribution to long-term…
  • Abstract Number: 71 • 2012 ACR/ARHP Annual Meeting

    The Association Between Preclinical Markers for Cardiovascular Disease and Rheumatoid Arthritis-Related Autoantibodies in First-Degree Relatives without Rheumatoid Arthritis

    Ryan W. Gan1, Jan M. Hughes-Austin2, Kevin D. Deane3, Elaine M. Urbina4, Peter K. Gregersen5, Michael H. Weisman6, V. Michael Holers7 and Jill M. Norris1, 1Epidemiology, Colorado School of Public Health, Aurora, CO, 2Epidemiology, Colorado School of Public Health / University of Colorado Anschutz Medical Campus, Aurora, CO, 3Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, 4Preventive Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 5Genomics and Human Genetics, Feinstein Institute for Medical Research, Manhasset, NY, 6Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, 7Rheumatology Division, University of Colorado School of Medicine, Aurora, CO

    Background/Purpose:   Rheumatoid arthritis (RA) is characterized by systemic inflammation and immune dysregulation, including the presence of autoantibodies and elevated inflammatory markers in subjects with…
  • Abstract Number: 72 • 2012 ACR/ARHP Annual Meeting

    Relationships Between Air Pollution and Presence of Rheumatoid Arthritis-Related Autoantibodies in Individuals without Rheumatoid Arthritis:  Studies of the Etiology of Rheumatoid Arthritis

    Ryan W. Gan1, Kevin D. Deane2, Gary O. Zerbe3, Michael H. Weisman4, Jane H. Buckner5, P. K. Gregersen6, Ted R. Mikuls7, James R. O'Dell8, Richard M. Keating9, V. Michael Holers10 and Jill M. Norris1, 1Epidemiology, Colorado School of Public Health, Aurora, CO, 2Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, 3Biostatistics and Informatics, Colorado School of Public Health / University of Colorado Anschutz Medical Campus, Aurora, CO, 4Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, 5Benaroya Research Institute at Virginia Mason, Seattle, WA, 6Genomics and Human Genetics, Feinstein Institute Medical Research and North Shore-Long Island Jewish Health System, Manhasset, NY, 7Internal Medicine, Omaha VA and University of Nebraska Medical Center, Omaha, NE, 8Dept of Internal Medicine, Univ of Nebraska Med Ctr, Omaha, NE, 9Rheumatology Section, The University of Chicago, Chicago, IL, 10Rheumatology Division, University of Colorado School of Medicine, Aurora, CO

    Background/Purpose:   Rheumatoid arthritis (RA) is characterized by the presence of circulating autoantibodies, which can be predictive of future RA development in currently unaffected individuals. …
  • Abstract Number: 73 • 2012 ACR/ARHP Annual Meeting

    Trends in 21st century Health Care Utilization in a Rheumatoid Arthritis Cohort Compared to the General Population

    Sofia Hagel1, Ingemar F. Petersson2, Ann B. I. Bremander3, Elisabet Lindqvist4, Charlotte Bergknut5 and Martin Englund6, 1Department of Clinical Sciences Lund, Section for Rheumatology, Lund, Lund University and Skåne University Hospital, Lund, Sweden, 2Lund University, Lund, Sweden, 3Department of Exercise Physiology, Biomechanics and Health, Halmstad University School of Business and Engineering,, Halmstad, Sweden, 4Department of Clinical Sciences, Lund, Section for Rheumatology, Lund, Lund University and Skåne University Hospital, Lund, Sweden, 5Department of Orthopedics, Lund University, Lund, Sweden, 6Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden

    Background/Purpose: To study twenty-first century trends in health care utilization by rheumatoid arthritis (RA) patients compared to the general population. Methods: Observational cohort study; using Swedish…
  • Abstract Number: 74 • 2012 ACR/ARHP Annual Meeting

    Length of Stay for Rheumatoid Arthritis Related Orthopedic Surgery Has Improved Over the Past 3 Decades and Is Related to Disease Markers. Results From Two UK Multicentre Inception Cohorts (1986-2011) Compared with National Data

    Elena Nikiphorou1, Stephen Morris2, David James3, Patrick D. Kiely4, David Walsh5 and Adam Young6, 1Research Department of Epidemiology & Public Health, UCL and Rheumatology, St Albans City Hospital, ERAS, St Albans City Hospital and University College London (UCL), St Albans, United Kingdom, 2Epidemiology and Public Health, Research Department of Epidemiology and Public Health, 1-19 Torrington Place, United Kingdom, 3Rheumatology, Diana Princess of Wales Hospital, Grimsby, United Kingdom, 4Rheumatology Dept, St. Georges Hospital, London, United Kingdom, 5Academic Rheum/Clin Sci Bldg, City Hospital, Nottingham, United Kingdom, 6Rheumatology, ERAS, St Albans City Hospital, St Albans, United Kingdom

    Background/Purpose: Length of Stay (LoS) is one of the main drivers of costs for orthopedic surgery in RA.  Better medical and surgical treatments in recent…
  • Abstract Number: 75 • 2012 ACR/ARHP Annual Meeting

    Patient-Reported Outcomes Associated with Achieving and Maintaining Low Disease Activity in Rheumatoid Arthritis

    Martin J. Bergman1, James W. Shaw2, Mary Cifaldi3, Gourab De4, Tony He5, Rajeev Ayyagari5 and James Signorovitch5, 1Taylor Hospital, Ridley Park, PA, 2Global Health Economics and Outcomes Research, Abbott Laboratories, Abbott Park, IL, 3Abbott Laboratories, Abbott Park, IL, 4Analysis Group, Inc., New York, NY, 5Analysis Group, Inc., Boston, MA

    Background/Purpose: Treat-to-target (T2T) guidelines for rheumatoid arthritis (RA) recognize low disease activity (LDA) as an acceptable therapeutic goal, particularly in patients with longstanding disease. The…
  • Abstract Number: 76 • 2012 ACR/ARHP Annual Meeting

    The Difference in Performance of DAS28 and RADAI During Pregnancy Might Explain Discrepancies Between Older and More Recent Studies On the Impact of Pregnancy On Rheumatoid Arthritis

    Jan Naterop1, Johanna M.W. Hazes2 and Radboud J.E.M. Dolhain3, 1Rheumatology, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, The Netherlands, Rotterdam, Netherlands, 2Rheumatology, Erasmus University Medical Center, Rotterdam, Netherlands, 3Rheumatology, Erasmus Medical Center, Rotterdam, Netherlands

    Background/Purpose: Pregnancy is the only condition in which Rheumatoid Arthritis (RA) shows spontaneous remission. Both older and more recent studies showed improvement of disease activity,…
  • Abstract Number: 77 • 2012 ACR/ARHP Annual Meeting

    Comorbid Conditions Do Not Explain Divergent Patient Assessments of Disease Activity and Global Health in Patients with Rheumatoid Arthritis

    Dörte Huscher1, Katja Thiele2, Sascha Bischoff2, Ulrich von Hinüber3, Guido Hoese4, Kirsten Karberg5, Wolfgang Ochs6 and Angela Zink7, 1German Rheumatism Research Centre and Charité University Medicine, Berlin, Germany, 2German Rheumatism Research Centre, Berlin, Germany, 3Rheumatologist in Private Practice, Hildesheim, Germany, 4Rheumatologist in Private Practice, Stadthagen, Germany, 5Rheumatologist in Private Practice, Berlin, Germany, 6Rheumatologist in Private Practice, Bayreuth, Germany, 7Epidemiology Unit, German Rheumatism Research Centre and Charité University Medicine, Berlin, Germany

    Background/Purpose: In the discussion of the 2010 ACR/EULAR remission criteria  the issue has been raised to what extent patients are able to distinguish rheumatoid arthritis…
  • Abstract Number: 78 • 2012 ACR/ARHP Annual Meeting

    Factors Influencing On the Discordance Between 2011 ACR/EULAR Criteria and Physician’s Clinical Judgment for Remission in Rheumatoid Arthritis Patients

    Yoon-Kyoung Sung1, Bo Young Yoon2, Soo-Kyung Cho1, Chan-Bum Choi1, Dae-Hyun Yoo3, Jae-Bum Jun3, Tae-Hwan Kim3, Shin-Seok Lee4, Tae-Jong Kim5, Jisoo Lee6, Jung-Yoon Choe7, Sung-Hoon Park8, Seung-Jae Hong9, Yeon-Ah Lee9, Jinseok Kim10, Eun-Mi Koh11, Hoon-Suk Cha11, Jaejoon Lee11, Won-Tae Chung12, Sung Won Lee12, Choong-Ki Lee13, Hye-Soon Lee14, Wan-Hee Yoo15, Young Mo Kang16 and Sang-Cheol Bae3, 1Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 2Inje University Ilsan Paik Hospital, Goyang, South Korea, 3Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 4Dept of Int Med/Rheumatology, Chonnam National University Medical School, Gwangju, South Korea, 5Rheumatology, Chonnam National University Medical School, Gwangju, South Korea, 6Internal Medicine, Ewha Womans University Mokdong Hospital, Seoul, South Korea, 7Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, South Korea, 8Catholic University of Daegu School of Medicine, Daegu, South Korea, 9Division of Rheumatology, Department of Internal Medicine, Kyung Hee University, Seoul, South Korea, 10Division of Rheumatology, Internal Medicine, Jeju National University Hospital, Jeju, Korea, South Korea, 11Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 12Rheumatology, Dong-A University Hospital, Busan, South Korea, 13Yeungnam University Hospital, Daegu, South Korea, 14Department of Rheumatology, Hanyang University Guri Hospital, Guri, South Korea, 15Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine, Jeonju, South Korea, 16Department of Internal Medicine (Rheumatology), Kyungpook National University School of Medicine, Daegu, South Korea

    Background/Purpose: Remission is a primary end point in the treatment of rheumatoid arthritis (RA). To ensure more uniform reporting of outcome measures, American College of…
  • Abstract Number: 79 • 2012 ACR/ARHP Annual Meeting

    Physician’s Global Assessment Is Affected by Physician’s Age and Gender, but Not by Patient Age and Gender in Rheumatoid Arthritis Patients Treated in Routine Care. Data From the Danish Nationwide Danbio Registry

    Cecilie Lindstrom Egholm1, Theodore Pincus2, Lene Dreyer3, Torkell Ellingsen4, Bente Glintborg3, Marcin Kowalski5, Tove Lorenzen4, Ole Rintek Madsen6, Henrik Nordin7, Claus Rasmussen8 and Merete L. Hetland9, 1Copenhagen University Hospital / DANBIO at Glostrup, Copenhagen, Denmark, 2Rheumatology, Rush University Medical Center, Chicago, IL, 3Copenhagen University Hospital at Gentofte, Gentofte, Denmark, 4Diagnostic Centre, Region Hospital Silkeborg, Silkeborg, Denmark, 5Aalborg University Hospital, Aalborg, Denmark, 6Dept. of Rheumatoglogy/C, Copenhagen University Hospital Gentofte, Hellerup, Denmark, 7Rigshospitalet, Copenhagen, Denmark, 8Vendsyssel Teaching Hospital/Aalborg University, Hjoerring, Denmark, 9Copenhagen University Hospital Glostrup, Copenhagen, Denmark

    Background/Purpose: Several studies have shown that significant discordance exists between patient (PATGL) and physician (DOCGL) global measures of rheumatoid arthritis (RA) disease activity. These studies…
  • Abstract Number: 80 • 2012 ACR/ARHP Annual Meeting

    Validation of Remission of Rheumatoid Arthritis by Traditional Disease Activity Score and Provisional Criteria by American College of Rheumatology and European League Against Rheumatism: Patient Reported Outcomes Analyzed From 3 Phase III Golimumab Trials

    Chenglong Han1, Edward Keystone2, Roy Fleischmann3, Josef S. Smolen4, Paul Emery5, Mark C. Genovese6, Mittie K. Doyle7 and Elizabeth C. Hsia7, 1Outcomes Research, Johnson & Johnson Pharmaceutical Services, LLC, Malvern, PA, 2Rebecca MacDonald Centre for Arthritis and Autoimmune Disease, University of Toronto, Toronto, ON, Canada, 3Southwestern Medical Center at Dallas, University of Texas, Dallas, TX, 4Division of Rheumatology, Department of Internal Medicine III,, Medical University of Vienna and Hietzing Hospital, Vienna, Austria, 5Medicine, Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, 6Division of Rheumatology, Stanford University, Palo Alto, CA, 7Janssen Research and Development, LLC, Spring House, PA

    Background/Purpose: Remission by Boolean-based definition (all scores on the tender joint and swollen joint count, CRP (mg/dL), and patient global assessment ≤1) and by Simplified…
  • Abstract Number: 81 • 2012 ACR/ARHP Annual Meeting

    Transitions Among Disease Activity States: Estimates and Models of Covariate Associations

    George W. Reed1, David H. Collier2, Andrew S. Koenig3, Katherine C. Saunders4, Joel M. Kremer5 and Sameer Kotak6, 1University of Massachusetts Medical School, Worcester, MA, 2Amgen Inc., Thousand Oaks, CA, 3Specialty Care, Pfizer Inc, Collegeville, PA, 4Corrona, LLC., Southborough, MA, 5Albany Medical College and The Center for Rheumatology, Albany, NY, 6Specialty Care, Pfizer Inc., New York, NY

    Background/Purpose:   Many RA patients have variable disease activity over time due to disease variability, reduction in efficacy of current medications, environmental factors and other…
  • Abstract Number: 82 • 2012 ACR/ARHP Annual Meeting

    Variability of the SF-6D Determinants Over Time in Early Arthritis:Results From the Espoir Cohort

    Cécile Gaujoux-Viala1, Bruno Fautrel2, Kossar Hosseini3, Francis Guillemin3, René-Marc Flipo4 and Anne-Christine Rat5, 1Lorraine University, Paris Descartes University, APEMAC, EA 4360, F- 54 000, Nancy; Paris 6 – Pierre et Marie Curie University; Rheumatology, Pitié-Salpêtrière Hospital, Paris, France, 2APHP, Pitié-Salpêtrière University Hospital, Paris, France, 3Lorraine University, Paris Descartes University, APEMAC, EA 4360, F- 54 000, Nancy, France, 4Rheumatology Department, Lille University Hospital, Lille, France, 5CHU Nancy, Clinical Epidemiology and Evaluation, Université de Lorraine, Paris Descartes University, APEMAC, EA 4360, Nancy, France

     Background/Purpose: There is growing emphasis on the cost-effectiveness of treating rheumatoid arthritis. The SF-6D, derived from the SF36, is an indirect utility measure widely used…
  • Abstract Number: 83 • 2012 ACR/ARHP Annual Meeting

    Substantial Functional Disability Is the Key Determinant of Discrepancies Between EQ-5D and SF-6D Utility Measures in Early Arthritis: Results From the Espoir Cohort

    Cécile Gaujoux-Viala1, Bruno Fautrel2, Kossar Hosseini3, Francis Guillemin4, René-Marc Flipo5 and Anne-Christine Rat3, 1Rheumatology, Montpellier I University, Nîmes University Hospital, Nîmes, France, 2Rheumatology, UPMC - Paris 6 University, Paris, France, 3CHU Nancy, Clinical Epidemiology and Evaluation, Université de Lorraine, Paris Descartes University, APEMAC, EA 4360, Nancy, France, 4Université de Lorraine, Paris Descartes University, APEMAC, EA 4360, F- 54 000, Nancy, France, 5Rheumatology Department, Lille University Hospital, Lille, France

    Background/Purpose: The EQ-5D, a 5-dimensional multi-attribute questionnaire, and the SF-6D, derived from the SF36, are 2 indirect utility measures widely used to calculate quality-adjusted life-years…
  • Abstract Number: 84 • 2012 ACR/ARHP Annual Meeting

    Benefits of Treat-to-Target Guideline Compliance in Patients with Rheumatoid Arthritis: A Retrospective Claims Analysis

    Martin J. Bergman1, James W. Shaw2, Mary A. Cifaldi3, Annie Guerin4, Pooja Chopra5 and James Signorovitch5, 1Taylor Hospital, Ridley Park, PA, 2Global Health Economics and Outcomes Research, Abbott Laboratories, Abbott Park, IL, 3Abbott Laboratories, Abbott Park, IL, 4Analysis Group, Inc., Montreal, QC, Canada, 5Analysis Group, Inc., Boston, MA

    Background/Purpose: To achieve clinical remission/low disease activity in patients with rheumatoid arthritis (RA), the treat-to-target (T2T) guidelines recommend frequent disease monitoring through patient-rheumatologist interactions. The…
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