Abstracts Archive - Page 2412 of 2607 - ACR Meeting Abstracts

Abstract Number: 294 • 2013 ACR/ARHP Annual Meeting
Physical Activity In Children With Juvenile Idiopathic Arthritis (JIA): The LEAP (Linking Exercise, Activity and Pathophysiology in Childhood Arthritis) Study
Lori B. Tucker¹, Heather A. McKay², Leanne M. Ward³, Jaime Guzman¹, Adam Baxter-Jones⁴, Kiem Oen⁵, Alan M. Rosenberg⁶, Johannes Roth³, Elizabeth Stringer⁷, Rae SM Yeung⁸, Kristin M. Houghton⁹, Heather Macdonald¹⁰, Debbie Ehrmann Feldman¹¹, Ciaran M. Duffy¹² and LEAP Study Investigators¹³, ¹Rheumatology, BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada, ²Family Practice and Orthoepedics, University of British Columbia, Vancouver, BC, Canada, ³University of Ottawa, Ottawa, ON, Canada, ⁴College of Kinesiology, University of Saskatchewan, Saskatoon, SK, Canada, ⁵University of Manitoba, Winnipeg, MB, Canada, ⁶Department of Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada, ⁷Department of Rheumatology, IWK Health Centre, Halifax, NS, Canada, ⁸Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, ⁹University of British Columbia, Vancouver, BC, Canada, ¹⁰The University of British Columbia, Vancouver, BC, Canada, ¹¹Rehabilitation, Université de Montréal, Montreal, QC, Canada, ¹²Rheumatology, Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, ¹³BC Children's Hospital, Vancouver, BC, Canada
Background/Purpose: Although children with JIA have lower fitness levels than healthy peers, little is known about their level of habitual physical activity. The LEAP…
Abstract Number: 295 • 2013 ACR/ARHP Annual Meeting
Uveitis In The Nordic Juvenile Idiopathic Arthritis Cohort; High Incidence, Frequent Complications, and Gender Associated Risk Factors
Ellen Nordal^1,2, Lillemor Berntson³, Kristiina Aalto⁴, Suvi Peltoniemi⁵, Susan Nielsen⁶, Troels Herlin⁷, Anders Fasth⁸ and Marite Rygg^9,10, ¹Department of Pediatrics, University Hospital of North Norway, Tromsø, Norway, ²Department of Clinical Medicine, University of Tromsø, Tromsø, Norway, ³Department of Pediatrics, Uppsala University Hospital, Uppsala, Sweden, ⁴Department of Pediatrics,, Helsinki University Children's Hospital, Helsinki, Finland, ⁵Department of Pediatrics, Helsinki University Children's Hospital, Helsinki, Finland, ⁶Pediatric Rheumatology Unit, Juliane Marie Centret, Rigshospitalet, Copenhagen, Denmark, ⁷Pediatric Rheumatology Clinic, Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark, ⁸Department of Pediatrics, University of Gothenburg, Gothenburg, Sweden, ⁹Department of Laboratory Medicine, Children's and Women's health, Norwegian University of Science and Technology, Trondheim, Norway, ¹⁰Department of Pediatrics, St Olav University Hospital, Trondheim, Norway
Background/Purpose: Uveitis is the most common extra-articular manifestation of juvenile idiopathic arthritis (JIA). Both incidence and reported outcome varies, and population-based data are scarce. Early…
Abstract Number: 296 • 2013 ACR/ARHP Annual Meeting
Declines In Levels Of Disease Activity and Physical Disability In Children With Juvenile Idiopathic Arthritis Seen In Standard Clinical Care Over The Last 25 Years
Alessandro Consolaro¹, Stefano Lanni¹, Francesca Minoia¹, Sergio Davì¹, Sara Dalprà¹, Benedetta Schiappapietra¹, Rossana Pignataro¹, Cristina Ferrari¹, Alberto Martini^1,2 and Angelo Ravelli^3,4, ¹Pediatria II, Istituto Giannina Gaslini, Genova, Italy, ²Department of Pediatrics, University of Genova, Genova, Italy, ³PRINTO, Genoa, Italy, ⁴University of Genova, Genova, Italy
Background/Purpose: Over the last 3 decades there have been important advances in the management of juvenile idiopathic arthritis (JIA), which include the introduction of methotrexate…
Abstract Number: 297 • 2013 ACR/ARHP Annual Meeting
Plasma Nicotinamide Phosphoribosyltransferase Correlates With Markers Of Inflammation and May Predict Early Therapeutic Response To Low-Dose Methotrexate In Juvenile Idiopathic Arthritis
Ryan S. Funk¹, Leon van Haandel¹, Marcia Chan², Lanny J. Rosenwasser², Andrew Lasky³, Maria F. Ibarra⁴, Mark F. Hoeltzel⁵, S.Q. Ye⁶, J.S. Leeder¹ and Mara L Becker⁷, ¹Clinical Pharmacology and Medical Toxicology, Children's Mercy Hospital, Kansas City, MO, ²Pediatric Immunology Research, Children's Mercy Hospital, Kansas City, MO, ³Pediatrics Rheumatology, Children's Mercy Hospital, Kansas City, MO, ⁴Pediatric Rheumatolgy, Children's Mercy Hospital, Kansas City, MO, ⁵Rheumatology Section, Children's Mercy Hospital, Kansas City, MO, ⁶Medical Genetic Research, Children's Mercy Hospital, Kansas City, MO, ⁷Clinical Pharmacology and Rheumatology, Children's Mercy Hospital, Kansas City, MO
Background/Purpose: Despite a poor understanding of its biochemical role in the inflammatory process, nicotinamide phosphoribosyltransferase (NAMPT) has been implicated in a number of autoimmune…
Abstract Number: 298 • 2013 ACR/ARHP Annual Meeting
Preliminary Prospective Study Of Ultrasonography In Patients With Juvenile Idiopathic Arthritis In Clinical Remission: Subclinical Synovitis May Predict Flare?
Vanessa B Miotto e Silva¹, Sônia A.V. Mitraud², Rita NV Furtado³, Jamil Natour³ and Maria Teresa Terreri¹, ¹Pediatrics, Escola Paulista de Medicina/ Universidade Federal de São Paulo, São Paulo, Brazil, ²Radiology and Diagnostic Imaging, Escola Paulista de Medicina/ Universidade Federal de São Paulo (EPM/UNIFESP), São Paulo, Brazil, ³Internal Medicine, Escola Paulista de Medicina/ Universidade Federal de São Paulo, São Paulo, Brazil
Background/Purpose: Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in childhood and has variable prognosis, characterized by periods of activity and remission.…
Abstract Number: 299 • 2013 ACR/ARHP Annual Meeting
Phenotypic Cluster Analysis Of Juvenile Idiopathic Arthritis: Relationship To International Leagues Of Associations For Rheumatology Classification Criteria
Jay Mehta¹, Juan Lin², Norman T. Ilowite^3,4 and for The CARRA Registry Investigators⁵, ¹Pediatrics, Children's Hospital at Montefiore/Albert Einstein College of Medicine, Bronx, NY, ²Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY, ³Pediatrics, Albert Einstein College of Medicine, Bronx, NY, ⁴Pediatrics, The Children's Hospital at Montefiore, Bronx, NY, ⁵Multiple Affiliations, Palo Alto, CA
Phenotypic cluster analysis of Juvenile Idiopathic Arthritis: relationship to ILAR classification criteriaBackground/Purpose: The ILAR classification of Juvenile Idiopathic Arthritis (JIA) delineated categories of childhood chronic…
Abstract Number: 268 • 2013 ACR/ARHP Annual Meeting
Inflammatory Bowel Disease In Juvenile Idiopathic Arthritis Patients Upon Biologics
Deborah Barthel¹ and Gerd Horneff², ¹Paediatrics, Asklepios Clinic Sankt Augustin, Sankt Augustin, Germany, ²Department of Pediatrics, Centre of Pediatric Rheumatology, Sankt Augustin, Germany
Background/Purpose: Inflammatory bowel disease (IBD) is a matter of interest in patients with juvenile idiopathic arthritis (JIA) treated with biologics. Methods: Baseline demografics, clinical characteristics…
Abstract Number: 260 • 2013 ACR/ARHP Annual Meeting
Pain, Functional Impairment and Ultrasound Detected Changes In Patients With Erosive and Non-Erosive Hand Osteoarthritis
Olga Sleglova¹, Olga Ruzickova², Karel Pavelka³ and Ladislav Senolt⁴, ¹Institute of Rheumatology, Prague, Prague, Czech Republic, ²Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Prague, Czech Republic, ³Institute of Rheumatology and Department of Rheumatology, 1st Medical Faculty, Charles University Prague, Prague, Czech Republic, ⁴Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic
Background/Purpose: Hand osteoarthritis (HOA) is a common and frequent cause of pain. HOA is a heterogeneous group of disorders with two main subsets including non-erosive…
Abstract Number: 261 • 2013 ACR/ARHP Annual Meeting
Concordance Of Hip Pain With Radiographic Hip Osteoarthritis In An Urban US Community: The Framingham Osteoarthritis Study
Kyu Chan Kim¹, David T. Felson², Katherine D. Linsenmeyer³, Ali Guermazi⁴, Steven C. Vlad⁵, Mary M. Clancy⁶ and Jingbo Niu⁷, ¹Internal Medicine and Rheumatology, Boston Medical Center, Boston, MA, ²Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ³Internal Medicine, Boston Medical Center, Boston, MA, ⁴Boston University, Boston, MA, ⁵Clinical Epidemiology, Boston University, Boston, MA, ⁶School of Medicine, Boston University, Boston, MA, ⁷Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA
Background/Purpose: While it is well known that knee pain and radiographic knee osteoarthritis (OA) are often discordant, little is known of the concordance of hip…
Abstract Number: 262 • 2013 ACR/ARHP Annual Meeting
Is There a Role For Non-Mendelian Inheritance In Severe Osteoarthritis Of The Knee
Allen D. Sawitzke¹, Richard Pimentel², Jathine Wong², Helena Martinez³, Marta Herrero³, Josep Verges⁴ and Daniel O. Clegg⁵, ¹Rheumatology, University of Utah, Salt Lake City, UT, ²University of Utah, Salt Lake, UT, ³Pharmascience Division, Bioiberica S.A., Barcelona, Spain, ⁴Pharmacological Research Unit, Scientific Medical Department, Bioibérica, S.A., Barcelona, Spain, ⁵Rheumatology, George Wahlen VA Medical Center/University of Utah, Salt Lake City, UT
Background/Purpose: Although the etiopathogenesis of osteoarthritis of the knee remains largely unknown, it is clear that genetic risks are contributory. Traditional family, twin, case control…
Abstract Number: 263 • 2013 ACR/ARHP Annual Meeting
“Generalized Osteoarthritis”: A Systematic Review
Amanda E. Nelson¹, Michael W. Smith² and Yvonne M. Golightly³, ¹University of North Carolina Thurston Arthritis Research Center, Chapel Hill, NC, ²Rheumatology, Saint Luke's Hospitals, Kansas City, MO, ³Gillings School of Global Public Health, Dept of Epidemiology, Thurston Arthritis Research Center, Injury Prevention Research Center, University of North Carolina Dept of Epidemiology, Chapel Hill, NC
Background/Purpose: To perform a systematic review of definitions, risk factors, and outcomes in "generalized osteoarthritis" (GOA). Methods: We performed a systematic review of Medline literature…
Abstract Number: 264 • 2013 ACR/ARHP Annual Meeting
The Proportion Of Knee Osteoarthritis Patients In Southern Sweden That Seek Medical Car
Aleksandra Turkiewicz¹, Maria Gerhardsson de Verdier², Gunnar Engström³, Stefan Lohmander¹ and Martin Englund¹, ¹Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden, ²Astra Zeneca R&D Molndal, Molndal, Sweden, Molndal, Sweden, ³Dept of Cardiovascular epidemiology, Clinical Sciences, Lund University, Lund, Sweden
Background/Purpose: To provide estimates of the proportion of subjects with knee osteoarthritis (OA) that seek healthcare for knee OA or joint pain within an 8-year…
Abstract Number: 265 • 2013 ACR/ARHP Annual Meeting
All-Cause Mortality and Incident Cardiovascular Disease In Knee Osteoarthritis: The Framingham Study
Devyani Misra¹, David T. Felson², Ida K. Haugen³, Martin Englund⁴ and Tuhina Neogi¹, ¹Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ²Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ³Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁴Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden
Background/Purpose: Studies examining the relation of osteoarthritis (OA) to mortality or cardiovascular disease (CVD) have reported conflicting results, raising the question of whether OA itself…
Abstract Number: 266 • 2013 ACR/ARHP Annual Meeting
Cardiovascular Disease In Osteoarthritis: Hip Versus Knee and The Influence Of Multiple Symptomatic Joint Involvement
Anthony V. Perruccio¹, Rita A. Kandel² and Aileen M. Davis³, ¹Toronto Western Hospital, Toronto Western Research Institute, and University of Toronto, Toronto, ON, Canada, ²Mount Sinai Hospital and University of Toronto, Toronto, ON, Canada, ³Health Care and Outcomes Research, Toronto Western Research Institute; Departments of Rehabilitation Science and Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada
Background/Purpose: The strength of association between obesity and osteoarthritis (OA) is reported to vary by joint (e.g. stronger association with knee than hip). As well,…
Abstract Number: 267 • 2013 ACR/ARHP Annual Meeting
Risk Of Falls Increases With Additional Symptomatic Osteoarthritic Joints: The Johnston County Osteoarthritis Project
Adam Dore¹, Yvonne M. Golightly², Vicki Mercer³, Jordan B. Renner⁴, Xiaoyan A. Shi⁵, Joanne M. Jordan⁶ and Amanda E. Nelson⁷, ¹Rheumatology, Allergy and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, ²Gillings School of Global Public Health, Dept of Epidemiology, Thurston Arthritis Research Center, Injury Prevention Research Center, University of North Carolina Dept of Epidemiology, Chapel Hill, NC, ³Division of Physical Therapy, Dept of Allied Health Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁴University of North Carolina Department of Radiology, Chapel Hill, NC, ⁵SAS Institute, Inc, Cary, NC, ⁶Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC, ⁷University of North Carolina Thurston Arthritis Research Center, Chapel Hill, NC
Background/Purpose: Falls, a growing problem among older adults, often lead to hospitalizations, surgeries, and death. Knee and hip osteoarthritis (OA) are known risk factors for…

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