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  • Abstract Number: 350 • 2013 ACR/ARHP Annual Meeting

    Cortical Bone Density As Measured By Digital X-Ray Radiogrammetry Correlates with Radiographic Joint Damage In The Hands Within 1 Year In Psoriatic Arthritis

    Agnes Szentpetery1, Muhammad Haroon2, Phil Gallagher3, Eric J. Heffernan4 and Oliver FitzGerald2, 1Rheumatology, Dublin Academic Medical Centre, St. Vincent's University Hospital, Dublin, Ireland, 2Department of Rheumatology, Dublin Academic Medical Centre, St. Vincent's University Hospital, Dublin, Ireland, 3Rheumatology, St. Vincent's University Hospital, Dublin, Ireland, 4Radiology, St. Vincent's University Hospital, Dublin, Ireland

    Background/Purpose: Structural destruction in peripheral joints may occur over time in both PsA and RA. We previously reported that 47% of early PsA patients treated…
  • Abstract Number: 351 • 2013 ACR/ARHP Annual Meeting

    Psoriatic Arthritis Mutilans: Clinical and Radiographic Definitions. A Systematic Review

    Amir Haddad1, Mansour Somaily2, Sindhu R. Johnson3, Rouhi Fazelzad4, Amie T. Kron5, Cathy Chau6 and Vinod Chandran7, 1Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Medicine, Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3Medicine, Toronto Scleroderma Program, Toronto Western Hospital, Toronto General Hospital, Mount Sinai Hospital, and University of Toronto, Toronto, ON, Canada, 4Health Sciences Libraries - Toronto General Hospital, University Health Network, Toronto, ON, Canada, 5Medicine, Toronto Scleroderma Program, Toronto Western Hospital, Mount Sinai Hospital, and University of Toronto, Toronto, ON, Canada, 6Medicine, Toronto Scleroderma Program, Toronto Western Hospital, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, 7Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose: Psoriatic Arthritis Mutilans (PAM) is the most severe form of psoriatic arthritis. Research on PAM has been impeded by the lack of an accepted…
  • Abstract Number: 352 • 2013 ACR/ARHP Annual Meeting

    Efficacy and Safety Of Vaccination Against seasonal 2012 Influenza Virus Among Patients With Psoriatic Arthritis and Psoriasis

    Arik Polackek1, Yuri Korobko1, Noa Madar-Balakirski1, Uri Arad2, David Levartovsky3, Ilana Kaufman4, Marina Anouk5, Irena Litinsky6, Ella Mendelson7, Daphna Paran8, Hagit Matz9, Dan Caspi10, Michal Mandelbaum11 and Ori Elkayam12, 1Rheumatology, Tel Aviv Medical Center, Tel Aviv, Israel, 2Department of Rheumatology, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, 3Rheumatology, Tel Aviv Medical Ctr, Tel Aviv, Israel, 4Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel-aviv, Israel, 5Rheumatology, Tel Aviv Sourasky Medical Ctr, Tel-Aviv University, Tel Aviv, Israel, 6Department of Rheumatology, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine Tel Aviv University, Tel Aviv, Israel, 7Central Virology Laboratory, Sheba Medical Center, Ramat Gan, Israel, 8Rheumatology, Tel Aviv Sourasky Medical Ctr, Tel-Aviv university, Tel Aviv, Israel, 9Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 10Rheumatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 11Central Virology Department, Sheba Medical Center, Tel Aviv, Israel, 12Rheumatology, Tel-Aviv Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel- Aviv, Israel

    Background/Purpose: Patients with psoriatic arthritis (PsA) and psoriasis (Pso) are considered to be immunosuppressed and are therefore recommended to receive vaccination against seasonal influenza. However,…
  • Abstract Number: 353 • 2013 ACR/ARHP Annual Meeting

    Time Interval Between The Onset Of Psoriasis and The Onset Of Psoriatic Arthritis May Define Disease Subsets

    Arane Thavaneswaran1, Vinod Chandran2 and Dafna D. Gladman2, 1Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 2Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose: Psoriatic Arthritis (PsA) is a heterogeneous disease with widely varying clinical features and outcomes. Phenotypic heterogeneity may reflect genetic heterogeneity. We aimed to investigate…
  • Abstract Number: 354 • 2013 ACR/ARHP Annual Meeting

    Disease Burden Among Patients With Psoriatic Arthritis Who Have Experienced First Line Tumor Necrosis Factor Inhibitor Regimen Failure In The European Union

    Siva Narayanan1, Yao Lu2, Richard Hutchings2 and Amanda Baskett2, 1Evidence Generation, Value and Access Center, Ipsos Healthcare, Columbia, MD, 2Ipsos Healthcare, London, United Kingdom

    Background/Purpose: Data on second line biologic patients who have experienced 1st line tumor necrosis factor inhibitor (TNF) failure and associated disease burden among patients (pts)…
  • Abstract Number: 355 • 2013 ACR/ARHP Annual Meeting

    Response To Etanercept With Or Without Methotrexate Combination Therapy In Patients With Psoriatic Arthritis

    Bernard Combe1, Urs Kerkmann2, Fiona Brock3 and Gaia Gallo2, 1Hôpital Lapeyronie-Service d'Immuno-rhumatologie, Montpellier, France, 2Pfizer Europe, Rome, Italy, 3Quanticate, Hitchin, Hertfordshire, United Kingdom

    Background/Purpose:  Randomized controlled trials in psoriatic arthrtitis (PsA) have allowed treatment with TNF inhibitors (TNFi) as monotherapy as well as co-medication with methotrexate (MTX), but…
  • Abstract Number: 356 • 2013 ACR/ARHP Annual Meeting

    Outcomes Of Patients With Rheumatoid Arthritis and Comorbid Hyperlipidemia

    L Rosenblatt1, JR Curtis2, G Yang1 and T Hebden3, 1Bristol-Myers Squibb, Plainsboro, NJ, 2University of Alabama at Birmingham, Birmingham, AL, 3Formerly of Bristol-Myers Squibb, Plainsboro, NJ

    Background/Purpose: Patients (pts) with RA have an increased prevalence of cardiovascular disease (CVD). Whether due to comorbidity or related to RA medications, many pts with…
  • Abstract Number: 358 • 2013 ACR/ARHP Annual Meeting

    Inflammatory Burden Predicts Carotid Plaque Progression and Subsequent Cardiovascular Events In Rheumatoid Arthritis: The 2-Year Prospective Cohort Study

    Churl Hyun Im1, Sang Hoon Kwon2, Jeong Soo Eun1, Na Ri Kim1, Eon Jeong Nam1 and Young Mo Kang3, 1Internal Medicine (Rheumatology), Kyungpook National University School of Medicine, Daegu, South Korea, 2Internal medicine (Rheumatology), Kyungpook National University School of Medicine, Daegu, South Korea, 3Department of Internal Medicine (Rheumatology), Kyungpook National University School of Medicine, Daegu, South Korea

    Background/Purpose: Rheumatoid arthritis (RA) patients have increased prevalence of carotid atherosclerosis, especially plaque formation, which has been associated with inflammatory burden in a previous study.…
  • Abstract Number: 359 • 2013 ACR/ARHP Annual Meeting

    Tocilizumab Treatment Increases Left Ventricular Ejection Fraction and Decreases Left Ventricular Mass Index In Rheumatoid Arthritis Patients Without Cardiac Symptoms : Assessment By Cardiac Magnetic Resonance Imaging At 3.0 Tesla

    Hitomi Kobayashi1,2, Isamu Yokoe3, Hiroshi Sato2, Yasuyuki Kobayashi4, Kihei Yoneyama5, Masaharu Hirano6 and Masami Takei7, 1Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 2Rheumatology, Itabashi Chuo Medical Center, Tokyo, Japan, 3Nihon University School of Medicine, Tokyo, Japan, 4Radiology, St.Marianna University School of Medicine, Kawasaki, Japan, 5Cardiology, St.Marianna University School of Medicine, Kawasaki, Japan, 6Cardiology, Tokyo Medical Colleage, Tokyo, Japan, 7Division of Hematology and Rheumatology, NIhon University School of Medicine, Tokyo, Japan

    Background/Purpose: Left ventricular (LV) dysfunction in rheumatoid arthritis (RA) may result, at least in part, from inflammation that may be regional and global. Therefore, therapies…
  • Abstract Number: 320 • 2013 ACR/ARHP Annual Meeting

    Sustained Improvement In Health-Related Quality Of Life, Work Productivity, Employability, and Reduced Healthcare Resource Utilization Of Patients With Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis Treated With Golimumab: 5-Year Results From 3 Phase III Studies

    Chenglong Han1, Arthur Kavanaugh2, Mark C. Genovese3, Benjamin Hsu4, Atul A. Deodhar5 and Elizabeth C. Hsia4, 1Janssen Global Services, LLC., Malvern, PA, 2University of California, San Diego, La Jolla, CA, 3Division of Rheumatology, Stanford University, Palo Alto, CA, 4Janssen Research & Development, LLC., Spring House, PA, 5Div of Arthritis & Rheum OP-09, Oregon Health & Science University, Portland, OR

    Background/Purpose: To summarize changes from baseline in health-related quality of life (HRQOL), impact of disease on work productivity, employability, and healthcare resource utilization among patients…
  • Abstract Number: 321 • 2013 ACR/ARHP Annual Meeting

    Evaluation and Comparison Of Performance Of Different Classification Criteria For Reactive Arthritis

    Mariana Benegas1, Rafael Chaparro1, Oscar L. Rillo2, Luciana Casalla1, Emilce Schneeberger3, Federico Ceccatto4, Sergio Paira5, Federico Zazzetti6, Juan C. Barreira7 and Emilio Busquiazzo8, 1Rheumatology, Hospital Gral. de Agudos Dr. E. Tornú, Buenos Aires, Argentina, 2Rheumatology Unit, Hospital General de Agudos Dr. E. Tornú, Buenos Aires, Argentina, 3Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 4Rheumatology, Hospital Jose María Cullen, Santa Fé, Argentina, 5Hospital Jose María Cullen, Santa Fé, Argentina, 6Rheumatology, Hospital Británico, Buenos Aires, Argentina, 7Rheumatology, British Hospital, Buenos Aires, Argentina, 8Rheumatology, Hospital del Milagro, Salta, Argentina

    Background/Purpose: Reactive Arthritis (Re.A) is an inflammatory joint disease that according to different records represents from 6% to 47% of the seronegative spondyloarthropathies (SS). These…
  • Abstract Number: 322 • 2013 ACR/ARHP Annual Meeting

    Ustekinumab Improves Physical Function, Quality Of Life, and Work Productivity Of Patients With Active Psoriatic Arthritis Who Were Methotrexate-naïve Or Previously Treated With Methotrexate Or Anti-Tumor Necrosis Factor Agent:Data From 2 Phase 3, Randomized, Placebo-Controlled Trials

    Proton Rahman1, Lluis Puig2, Alice B. Gottlieb3, Arthur Kavanaugh4, Iain B. McInnes5, Christopher T. Ritchlin6, Shu Li7, Yuhua Wang7, Ning Zhao8, Rita Ganguly8, Michael Song7, Alan M. Mendelsohn9 and Chenglong Han8, 1Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, 2Universitat Autònoma de Barcelona, Barcelona, Spain, 3Tufts Medical Center, Boston, MA, 4University of California, San Diego, La Jolla, CA, 5Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom, 6Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, 7Janssen Research & Development, LLC., Spring House, PA, 8Janssen Global Services, LLC., Malvern, PA, 9Immunology, Janssen Research & Development, LLC., Spring House, PA

    Background/Purpose: To examine the impact of ustekinumab (UST) treatment on patient reported outcomes in patients with active psoriatic arthritis (PsA) using week 24 data from…
  • Abstract Number: 323 • 2013 ACR/ARHP Annual Meeting

    Safety Of Ustekinumab From The Placebo-Controlled Periods Of Psoriatic Arthritis and Psoriasis Clinical Developmental Programs

    Iain B. McInnes1, Kim Papp2, Lluis Puig3, Kristian Reich4, Christopher T. Ritchlin5, Bruce Strober6, Proton Rahman7, Arthur Kavanaugh8, Alan M. Mendelsohn9, Michael Song10, Daphne Chan10, Yaung-Kaung Shen10, Shu Li10 and Alice B. Gottlieb11, 1Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom, 2Probity Research, Waterloo, ON, Canada, 3Universitat Autònoma de Barcelona, Barcelona, Spain, 4SCIderm Research Institute and Dermatologikum Hamburg, Hamburg, Germany, 5Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, 6University of Connecticut, Farmington, CT, 7Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, 8University of California, San Diego, La Jolla, CA, 9Immunology, Janssen Research & Development, LLC., Spring House, PA, 10Janssen Research & Development, LLC., Spring House, PA, 11Tufts Medical Center, Boston, MA

    Background/Purpose:   To describe the short-term safety experience of UST during the double-blind, PBO-controlled portion of the PsA & PsO clinical developmental programs. Methods: Safety…
  • Abstract Number: 324 • 2013 ACR/ARHP Annual Meeting

    Long-Term Safety Of Ustekinumab: 5 Years Of Follow-Up From The Psoriasis Clinical Development Program Including Patients With Psoriatic Arthritis

    Kim Papp1, Christopher E.M Griffiths2, Kenneth B. Gordon3, Mark Lebwohl4, Philippe O. Szapary5, Yasmine Wasfi5, Daphne Chan5, Yaung-Kaung Shen5, Vincent Ho6, Pierre-Dominique Ghislain7, Bruce Strober8 and Kristian Reich9, 1Probity Research, Waterloo, ON, Canada, 2Dermatology Centre, University of Manchester, Manchester, United Kingdom, 3Feinberg School of Medicine, Northwestern University, Chicago, IL, 4Mount Sinai Medical Center, New York, NY, 5Janssen Research & Development, LLC., Spring House, PA, 6University of British Columbia, Vancouver, BC, Canada, 77. Cliniques Universitaires Saint-Luc, Université Catholique de Louvain,, Brussels, Belgium, 8University of Connecticut, Farmington, CT, 9SCIderm Research Institute and Dermatologikum Hamburg, Hamburg, Germany

    Background/Purpose: Ustekinumab(UST) is approved for moderate-to-severe psoriasis (PsO), and is currently in Phase 3 development for psoriatic arthritis (PsA). We report the long-term safety experience…
  • Abstract Number: 326 • 2013 ACR/ARHP Annual Meeting

    Reduction Of Disease Burden On Workplace and Household Productivity In Psoriatic Arthritis Over 48 Weeks Of Treatment With Certolizumab Pegol

    Arthur Kavanaugh1, Dafna D. Gladman2, Désirée M. van der Heijde3, Oana Purcaru4 and Philip J. Mease5, 1Division of Rheumatology Allergy and Immunology, University of California San Diego, San Diego, CA, 2Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 4UCB Pharma, Brussels, Belgium, 5Division of Rheumatology Research, Swedish Medical Center and University of Washington, Seattle, WA

    Background/Purpose: Compared to the general population, patients (pts) with psoriatic arthritis (PsA) suffer greater amounts of disability and substantially lower employment rates.1 To date there…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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