Abstracts Archive - Page 2408 of 2425 - ACR Meeting Abstracts

Abstract Number: 191 • 2012 ACR/ARHP Annual Meeting
Analysis of Genes Involved in Autoinflammatory Diseases in Adult Onset Still’s Disease
Emma Garcia-Melchor¹, Dolors Grados², Eva Gonzalez-Roca¹, Elena Riera³, Manel Juan¹, Jordi Yagüe¹, Juan Ignacio Aróstegui¹, Javier Narváez⁴ and Alejandro Olivé⁵, ¹Immunology Department, Hospital Clinic Barcelona, Barcelona, Spain, ²Rheumatology Department, Hospital Universitario Germans Trias i Pujol, Badalona, Spain, ³Rheumatology Department, Hospital Mutua de Terrassa, Terrassa, Spain, ⁴Rheumatology Department, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Spain, ⁵Rheumatology, Hospital Universitario Germans Trias i Pujol, Badalona, Spain
Background/Purpose: Adult Onset Still’s Disease (AOSD) is a systemic inflammatory disease characterized by fever, skin rash, articular involvement, lymphadenopathy, hepatosplenomegaly and serositis. Due to the…
Abstract Number: 192 • 2012 ACR/ARHP Annual Meeting
Clinical and Laboratory Findings in A Cohort of Italian Patients with Adult Onset Still’S Disease: The Role of IL-18 As A Disease Biomarker
Roberta Priori¹, Serena Colafrancesco², Carlo Perricone², Antonina Minniti², Cristiano Alessandri², Giancarlo Iaiani³ and Guido Valesini², ¹Department of Internal Medicine and Medical Specialties, Sapienza University, Rome, Italy, ²Rheumatology Unit, Sapienza University of Rome, Rome, Italy, ³Department of Infectious Diseases and Tropical Medicine, Sapienza University of Rome, Rome, Italy
Background/Purpose: Adult Onset Still's Disease (AOSD) is a systemic inflammatory syndrome driven by interleukin (IL)-18. Since differential diagnosis between AOSD, sepsis and other inflammatory conditions…
Abstract Number: 193 • 2012 ACR/ARHP Annual Meeting
Tocilizumab in Adult Still’s Disease : The Israeli Experience
Ori Elkayam¹, Nizar Jiries², Zvi Dranitzki³, Shaye Kivity⁴, Merav Lidar⁵, Ofer Levy⁶, Mahmoud Abu-Shakra⁷, Hagit Sarvagil-Maman⁸, Hagit Padova⁸, Dan Caspi⁹ and Itzhak Rosner¹⁰, ¹Rheumatology, Tel-Aviv Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel- Aviv, Israel, ²Rheumatology, Bnai Zion Medical Center, Israel, ³Medicine, Hadassah hebrew university, Jerusalem, Israel, ⁴Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, affliated to Sackler Faculty of Medicine, Tel-Aviv University Israel, Tel-Aviv, Israel, ⁵Medicine F, Sheba Medical Center, Ramat Gan, Israel, ⁶Rheumatology, Asaf Harofe Medical Center, ⁷Medicine and Rheumatology, Soroka Medical Centre and Ben Gurion University, Beer-Sheva, Israel, ⁸Rheumatology, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, ⁹Rheumatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ¹⁰Rheumatology, Bnai Zion Medical Center / Technion Faculty of Medicine, Haifa, Israel
Background/Purpose: The objective of this study was to review the clinical and laboratory characteristics of patients with adult's Still disease treated with tocilizumab (TCZ) in…
Abstract Number: 194 • 2012 ACR/ARHP Annual Meeting
LONG-TERM Efficacy of Tocilizumab in A Patient with Amyloidosis and Interstitial Pneumonia Secondary to Multicentric Castleman’s Disease (MCD)
Michihito Katayama¹, Soichiro Tsuji¹, Satoshi Teshigawara¹, Eriko Kudo-Tanaka¹, Maiko Yoshimura¹, Akane Watanabe¹, Akiko Yura², Yoshinori Harada³, Yoshinori Katada³, Jun Hashimoto¹, Masato Matsushita⁴, Yukihiko Saeki⁵ and Shiro Ohshima⁵, ¹Dept of Rheumatology, Osaka-Minami Medical Center, Kawachinagano City, Japan, ²Dept of Allergology, Allergology,Osaka-Minami Medical Center, Kawachinagano City, Japan, ³Dept of Allergology, Kawachinagano City, Japan, ⁴Rheumatology, Osaka Minami Medical Center, Osaka, Japan, ⁵Dept of Clinical Research, Osaka-Minami Medical Center, Kawachinagano City, Japan
Background/Purpose: Castleman’s disease is a benign lymphoproliferative disorder characterized histologically by follicular hyperplasia and capillary proliferation with endothelial hyperplasia. In addition, overproduction of Interleukin-6 (IL-6)…
Abstract Number: 195 • 2012 ACR/ARHP Annual Meeting
Inflammatory Arthritis in Patients with Myelodysplastic Syndrome: French Multicenter Retrospective Study
Arsene Mekinian¹, Olivier Decaux², Geraldine Falgarone³, Thorsten Braun Sr.⁴, Eric Toussirot⁵, Loic Raffray⁶, Bruno Gombert⁷, Bruno de Wazieres⁸, Anne Laure Buchdaul⁹, Jean-Marc Ziza¹⁰, David Launay¹¹, Guillaume Denis¹², Serge Madaule¹³, Pierre Fenaux¹⁴ and Olivier Fain¹⁵, ¹Internal Medicine, Jean Verdier Hospital, Bondy, FL, France, ²Department of Internal Medicine, Rennes University Hospital, Rennes, France, ³Rheumatology, Hopital avicenne, Paris, France, ⁴Hematology, Avicenne hospital, Bobigny, France, ⁵Université de Franche Comté , CHRU, CIC Biotherapy 506 and Rheumatology and EA 4266 Pathogens and Inflammation, Besançon, France, ⁶Internal Medicine, CHU de Bordeaux, Bordeaux, France, ⁷Internal Medicine, La Rochelle hospital, La Rochelle, France, ⁸Internal Medecine, CHU de Nimes, Nimes, France, ⁹Internal Medicine, Douai hospital, Douai, France, ¹⁰Rheumatology, Croix Saint Simon Hospital, Paris, France, ¹¹Internal Medicine, Claude Huriez University Hospital, Lille, France, ¹²Internal Medicine, Rochefoucault hospital, Rochefoucault, France, ¹³Rheuamtology, Albi hospital, Albi, France, ¹⁴Hematology, Avicenne Hospital, France, ¹⁵Internal Medicine, Jean Verdier Hospital, Bondy, France
Inflammatory arthritis in patients with myelodysplastic syndrome: French multicenter retrospective study.For the Société Nationale Française de Médecine Interne (SNFMI), the CRI (Club Rhumatismes Inflammation) and…
Abstract Number: 196 • 2012 ACR/ARHP Annual Meeting
Sarcoidosis in Northern New England. Clinical Characteristics and Predictive Factors for More Aggressive Therapy
Alireza Meysami¹, Kevin F. Spratt² and Christopher M. Burns³, ¹Rheumatology, Dartmouth Hitchcock Medical Center, Lebanon, NH, ²Department of Orthopaedic Surgery, Geisel School of Medicine at Dartmouth, Lebanon, NH, ³Dartmouth Medical School, Lebanon, NH
· Background/Purpose: Sarcoidosis is characterized by a variable clinical presentation. DMARDs and biologics have been used for resistant and/or organ-threatening disease. We analyzed the cases…
Abstract Number: 197 • 2012 ACR/ARHP Annual Meeting
Collapsing Glomerulopathy in Collagen Vascular-Like Disease
Rawad Nasr¹, Christine Johns² and Elie Gertner³, ¹Rheumatology - Internal Medicine, University of Minnesota, Minneapolis, MN, ²Section of Nephrology, Regions Hospital, St Paul, MN, ³Section of Rheumatology, Regions Hospital and University of Minnesota Medical School, St. Paul, MN
Background/Purpose: Background: Collapsing Glomerulopathy (CG) is an uncommon podocytopathy with distinct clinical and pathological characteristics. It is usually associated with HIV disease or parvovirus B19…
Abstract Number: 198 • 2012 ACR/ARHP Annual Meeting
Diagnostic Predictors and Clinical Outcomes in Patients Presenting Solely with Lymphadenopathy
Huifang Lu, Xerxes Pundole and Khanh Vu, General Internal Medicine, UT MD Anderson Cancer Center, Houston, TX
Background/Purpose: Patients presenting solely with radiologic evidence of lymphadenopathy (LAD) to tertiary cancer centers are often diagnosed with malignancy or autoimmune diseases such as sarcoidosis.…
Abstract Number: 199 • 2012 ACR/ARHP Annual Meeting
Joint, Hand and Feet Swelling As a Presenting Symptom of Hereditary Angioedema
Maria J. Gutierrez¹ and Timothy J. Craig², ¹Department of Pediatrics, Division of Pediatric Rheumatology. Department of Medicine, Section of Allergy and Immunology, Penn State College of Medicine Milton S. Hershey Medical Center, Hershey, PA, ²Department of Medicine. Division of Pulmonary, Allergy and Critical Care Medicine, Penn State College of Medicine Milton S. Hershey Medical Cente, Hershey, PA
Background/Purpose: Hereditary Angioedema (HAE) is a rare disorder caused by deficiency or impaired function of C1 esterase inhibitor. Early and accurate diagnosis of HAE is…
Abstract Number: 200 • 2012 ACR/ARHP Annual Meeting
Rheumatic Manifestations and Connective Tissue Diseases in Autoimmune Hepatitis of the Child and the Adult
Federico Zazzetti¹, Nora C. Fernandez², Javier Benavidez², Luis A. Colombato³, Graciela R. Rodriguez⁴, Graciela Nardi⁵, Carolina Bru Morón⁶, Oscar L. Rillo⁷, Nelo A. Quadrini⁸, Stella M. Garay⁹, Mariana Fabi⁹, Teresita Gonzalez¹⁰ and Juan C. Barreira¹¹, ¹Rheumatology, Buenos Aires Hospital Britanico, Buenos Aires, Argentina, ²Hepatology, Buenos Aires British Hospital, Buenos Aires, Argentina, ³Gastroenterology, Buenos Aires British Hospital, Buenos Aires, Argentina, ⁴Rheumatology, Hospital Dr. Ignacio Pirovano, Buenos Aires, Argentina, ⁵Gastroenterology, Hospital Dr. Ignacio Pirovano, Buenos Aires, Argentina, ⁶Rheumatology, Hospital Dr. Enrique Tornú, Buenos Aires, Argentina, ⁷Rheumatology, Hospital General de Agudos "Dr. E. Tornú", Buenos Aires, Argentina, ⁸Gastroenterology, Hospital Dr. Enrique Tornú, Buenos Aires, Argentina, ⁹Rheumatology, Hospital IAEP Sor María Ludovica, La Plata, Argentina, ¹⁰Hepatology, Hospital IAEP Sor María Ludovica, La Plata, Argentina, ¹¹Rheumatology, Buenos Aires British Hospital, Buenos Aires, Argentina
Background/Purpose: Autoimmune hepatitis (AIH) is a progressive fibrosing inflammatory disease of the liver of unknown etiology, leading to cirrhosis. Its course is usually fluctuating and…
Abstract Number: 201 • 2012 ACR/ARHP Annual Meeting
High Rate of Autoimmune Manifestations During Idiopathic CD4 Lymphocytopenia
Alexis Régent¹, Brigitte Autran², Guislaine Carcelain², Benjamin Terrier³, Alain Krivitzky⁴, Eric Oksenhendler⁵, Nathalie Costedoat-Chalumeau⁶, Pascale Hubert², Olivier Lortholary⁷, Nicolas Dupin⁸, Patrice Debré², Loic Guillevin⁹ and Luc Mouthon¹, ¹Internal Medicine, Hopital Cochin, Paris, France, ²INSERM, UMR945, AP-HP, Hôpital Pitié-Salpêtrière, Laboratoire d'Immunologie Cellulaire Et Tissulaire, Paris, France, ³National Referral Center for Rare Systemic Autoimmune Diseases, Cochin Hospital, Paris, France, ⁴Département de médecine interne, Hôpital Avicenne, AP-HP, Bobigny, France, ⁵Département d'Immunologie Clinique, Hôpital Saint-Louis, AP-HP, Paris, France, ⁶Internal Medicine, Assistance Publique-Hôpitaux de Paris, Hopital Pitié-Salpétrière, Paris, France, ⁷Service de maladies infectieuses, Hôpital Necker-Enfants malades, AP-HP, Paris, France, ⁸Service de Dermatologie, Hôpital Cochin, AP-HP, Paris, France, ⁹Department of Internal Medicine, Referral Center for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, Paris, France
Background/Purpose: When first described by the Center for Disease Control, idiopathic CD4 lymphocytopenia (ICL) was characterized by opportunistic infections in patients with a CD4 count≤300/mm3…
Abstract Number: 202 • 2012 ACR/ARHP Annual Meeting
Diseases Associated with Markedly Elevated Ferritin Levels
Reshma Marri¹, Payal J. Patel², Amita Thakkar³, Rochella A. Ostrowski⁴, Eric McBride¹ and Rodney Tehrani⁵, ¹Rheumatology, Loyola Univ Medical Ctr, Maywood, IL, ²Internal Medicine, Loyola Univ Medical Ctr, Maywood, IL, ³Loyola Univ Medical Ctr, Maywood, IL, ⁴Rheumatology, Loyola University Medical Center, Maywood, IL, ⁵Allergy, Immunology, and Rheumatology, Loyola University Medical Center, Maywood, IL
Background/Purpose: Adult onset Still’s disease (AOSD) is a rare form of inflammatory arthritis with inflammatory systemic disease of unknown etiology. It is a diagnosis of…
Abstract Number: 203 • 2012 ACR/ARHP Annual Meeting
Clinical Course Factors Associated with Outcome of Monoarthritis : A Retrospective Study of 173 Cases
Hyemin Jeong¹, Eun-Jung Park¹, Jiwon Hwang¹, Ji Young Chai², Joong Kyong Ahn³, Eun-Mi Koh⁴ and Hoon-Suk Cha¹, ¹Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, ²Division of Rheumatology, Jesang Hospital, Seongnam-si Gyeonggi-do, South Korea, ³Department of Medicine, Kangbuk Samsung hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea, ⁴Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Seoul, South Korea
Background/Purpose: To evaluate the clinical features and outcomes in patients with monoarthritis and to investigate predictive factors associated with the clinical course in terms of…
Abstract Number: 204 • 2012 ACR/ARHP Annual Meeting
Characterization of Joint Disease in Mucopolysaccharidosis Type I Mice and the Effects of Enzyme Replacement Therapy
Patricia Oliveira¹, Guilherme Baldo², Fabiana Mayer², Barbara Martinelli², Luise Meurer³, Roberto Giugliani², Ursula Matte² and Ricardo M. Xavier⁴, ¹Rheumatology, Hospital de Clinicas de Porto Alegre, Porto Alegre, Brazil, ²Genetics, Hospital de Clinicas de Porto Alegre, ³Pathology, Hospital de Clinicas de Porto Alegre, ⁴Rheumatology Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil
Background/Purpose: Mucopolysaccharidosis type I (MPS I) is a lysosomal disorder caused by deficiency of alpha-L-iduronidase, which leads to storage of glycosaminoglycans. Patients with MPS I…
Abstract Number: 205 • 2012 ACR/ARHP Annual Meeting
Idiopathic Inflammatory Myositis Is Associated with an Increased Incidence of Systemic Sclerosis
Shreyas H. Chaudhary¹, Susanna Proudman² and Vidya S. Limaye³, ¹Medical Student University of Adelaide, Adelaide, Australia, ²Rheumatology Unit, Royal Adelaide Hospital, Adelaide, Australia, ³Royal Adelaide Hospital, Adelaide, Australia
Background/Purpose: Systemic sclerosis (SSc) and idiopathic inflammatory myositis (IIM) are two systemic autoimmune connective tissue diseases with predominant effects on skin and muscle respectively .…

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