Abstracts Archive - Page 2406 of 2607 - ACR Meeting Abstracts

Abstract Number: 361 • 2013 ACR/ARHP Annual Meeting
Risk Of Venous Thromboembolism and Use Of Disease-Modifying Antirheumatic Drugs For Rheumatoid Arthritis
Seoyoung C. Kim¹, Daniel H. Solomon^2,3, Jun Liu⁴, Jessica M. Franklin⁵, Robert J. Glynn⁶ and Sebastian Schneeweiss⁷, ¹Div. of Pharmacoepidemiology and Pharmacoeconomics, Div. of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ²Division of Pharmacoepidemiology, Harvard Medical School, Brigham and Women's Hospital, Division of Rheumatology, Division of Pharmacoepidemiology, Boston, MA, ³Division of Rheumatology, Brigham and Women's Hospital, Boston, MA, ⁴Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Harvard Medical School, Boston, Boston, MA, ⁵Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Boston, MA, ⁶Brigham and Women's Hospital, Boston, MA, ⁷Division of Pharmacoepidemiology, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Recent research suggests that rheumatoid arthritis (RA), an autoimmune systemic inflammatory disease, increases the risk of venous thromboembolism (VTE) including pulmonary embolism and deep…
Abstract Number: 362 • 2013 ACR/ARHP Annual Meeting
Management Of Hyperlipidemia In Patients With RA: Results From The Corrona Certain Study
Dimitrios A. Pappas¹, Ani John², Joel M. Kremer³, George W. Reed⁴, Tanya Sommers⁴, Jeffrey D. Greenberg⁵, Ashwini Shewade² and Jeffrey R. Curtis⁶, ¹Columbia University, New York, NY, ²Genentech Inc., South San Francisco, CA, ³Albany Medical College and The Center for Rheumatology, Albany, NY, ⁴CORRONA, Inc., Southborough, MA, ⁵NYU Hospital for Joint Diseases, New York, NY, ⁶7University of Alabama at Birmingham Division of Clinical Immunology and Rheumatology, Birmingham, AL
Background/Purpose: RA is associated with an increased risk for cardiovascular disease (CVD).1 Patients (pts) with RA share similar risk for CVD with non-RA pts who are 10 years older…
Abstract Number: 363 • 2013 ACR/ARHP Annual Meeting
Comparing Myocardial Infarction Risks Associated With Biologics Of Varying Mechanisms Of Action Among Older RA Patients
Jeffrey R. Curtis¹, Huifeng Yun², Jie Zhang³, Fenglong Xie⁴, Lang Chen⁵, Emily Levitan², James Lewis⁶, Timothy Beukelman⁷, Kenneth G. Saag⁸ and Iris Navarro-Millan⁵, ¹University of Alabama at Birmingham, Division of Clinical Immunology and Rheumatology, Birmingham, AL, ²Epidemiology, University of Alabama at Birmingham, Birmingham, AL, ³Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁴Rheumatology & Immunology, University of Alabama at Birmingham, Birmingham, AL, ⁵Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁶Medicine, University of Pennsylvania, Philadelphia, PA, ⁷Pediatric Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁸Immunology & Rheumatology, The University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Anti-TNF biologics have been associated with a reduced risk for acute myocardial infarction (AMI) in some rheumatoid arthritis (RA) populations. The comparative risks for…
Abstract Number: 364 • 2013 ACR/ARHP Annual Meeting
Hyperuricemia As a Risk Factor for Cardiovascular Disease in Patients With Rheumatoid Arthritis
Daniel Kuo¹, Cynthia S. Crowson², Sherine E. Gabriel³ and Eric L. Matteson⁴, ¹Mayo Medical School, Mayo Clinic, Rochester, MN, ²Department of Health Sciences Research, Mayo Clinic, Rochester, MN, ³Health Sciences Research & Div of Rheumatology, Mayo Clinic, Rochester, MN, ⁴Rheumatology, Mayo Clinic, Rochester, MN
Background/Purpose: Patients with rheumatoid arthritis (RA) are at increased risk of developing cardiovascular disease (CVD). There is growing evidence that serum uric acid plays an important…
Abstract Number: 365 • 2013 ACR/ARHP Annual Meeting
Oral Calcium Supplementation Is Associated With Subclinical Atherosclerosis In Rheumatoid Arthritis
Shanthi Dhaduvai¹, Laura Geraldino-Pardilla², Jon T. Giles³ and Joan M. Bathon⁴, ¹Division of Rheumatology, Columbia University Medical Center, New York, NY, ²Division of Rheumatology, Columbia University, College of Physicians and Surgeons, New York, NY, ³Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, ⁴Columbia University, New York, NY
Background/Purpose: Recent studies in the general population highlight possible adverse cardiovascular effects with calcium supplementation; however, the association between calcium intake and subclinical markers of…
Abstract Number: 366 • 2013 ACR/ARHP Annual Meeting
Traditional Cardiac Risk Factors Predict Significant Coronary Plaque Burden In Asymptomatic Patients With Rheumatoid Arthritis
George A. Karpouzas¹, Jennifer Malpeso², Tae-Young Choi², Youngju Pak³ and Matthew Budoff², ¹Rheumatology, Harbor-UCLA Medical Center, Torrance, CA, ²Cardiology, Harbor-UCLA Medical Center, Torrance, CA, ³Biostatistics, Harbor-UCLA Medical Center, Torrance, CA
Background/Purpose: Computed tomography angiography (CTA) provides prognostic information in patients with suspected but unknown coronary artery disease (CAD); subjects without plaque had no incident major…
Abstract Number: 367 • 2013 ACR/ARHP Annual Meeting
Cytomegalovirus-Related Immunity Correlates With Myocardial Disease In Rheumatoid Arthritis
John M. Davis III¹, Cynthia S. Crowson², Michael A. Strausbauch³, Terry M. Therneau², Eric L. Matteson¹, Keith L. Knutson³ and Sherine E. Gabriel⁴, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Department of Health Sciences Research, Mayo Clinic, Rochester, MN, ³Immunology, Mayo Clinic, Rochester, MN, ⁴Health Sciences Research & Div of Rheumatology, Mayo Clinic, Rochester, MN
Background/Purpose: We recently discovered correlations between a profile of cytokines produced in response to human cytomegalovirus (CMV), poor treatment outcome, and erosive joint damage. The…
Abstract Number: 368 • 2013 ACR/ARHP Annual Meeting
Detrimental Impact Of Long-Term Cumulative Burden Of Rheumatoid Arthritis (RA) Disease Severity On Cardiovascular Outcomes In RA
Elena Myasoedova¹, Birkan Ilhan², Helen Khun³, Eric L. Matteson⁴ and Cynthia S. Crowson³, ¹Internal Medicine and Rheumatology, Mayo Clinic, Rochester, MN, ²Internal Medicine, Marmara University, School of Medicine, Istanbul, Turkey, ³Department of Health Sciences Research, Mayo Clinic, Rochester, MN, ⁴Rheumatology, Mayo Clinic, Rochester, MN
Background/Purpose: Several studies have shown the associations of various measures of rheumatoid arthritis (RA) disease severity with unfavorable cardiovascular (CV) outcomes in RA. The association…
Abstract Number: 369 • 2013 ACR/ARHP Annual Meeting
Prolongation Of QT Interval In Patients With Rheumatoid Arthritis and Its Impact On Mortality: Results From a Population-Based Study
Krati Chauhan¹, Michael Ackerman², Cynthia S. Crowson³, Eric L. Matteson¹ and Sherine E. Gabriel⁴, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Division of Cardiology, Mayo Clinic, Rochester Minnesota, Rochester, MN, ³Department of Health Sciences Research, Mayo Clinic, Rochester, MN, ⁴Health Sciences Research & Div of Rheumatology, Mayo Clinic, Rochester, MN
Background/Purpose: Patients with rheumatoid arthritis (RA) are at increased risk of cardiovascular morbidity and mortality. This risk persists even when RA disease characteristics are taken…
Abstract Number: 370 • 2013 ACR/ARHP Annual Meeting
Shift In Cardiovascular Risk and Lipid Levels In Rheumatoid Arthritis Patients Using ATP-3 Guidelines: Corrona Certain Study
Dimitrios A. Pappas¹, Ani John², Jeffrey R. Curtis^3,4, George W. Reed⁵, Tanya Sommers⁵, Jeffrey D. Greenberg⁶, Ashwini Shewade² and Joel M. Kremer⁷, ¹Columbia University, New York, NY, ²Genentech Inc., South San Francisco, CA, ³Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁴University of Alabama at Birmingham, Division of Clinical Immunology and Rheumatology, Birmingham, AL, ⁵CORRONA, Inc., Southborough, MA, ⁶Departments of Medicine (Rheum Div) and Hospital for Joint Diseases, New York Hospital for Joint Diseases, New York, NY, ⁷Albany Medical College and The Center for Rheumatology, Albany, NY
Background/Purpose: RA is associated with an increased risk for cardiovascular (CV) disease. Hyperlipidemia is a recognized risk factor for CVD. This study followed the changes…
Abstract Number: 371 • 2013 ACR/ARHP Annual Meeting
Inflammatory Cell Infiltrates In The Heart Of Patients With Coronary Artery Disease With and Without Inflammatory Rheumatic Disease: A Biopsy Study
Jacqueline Kirsti Andersen¹, Ingvild Oma², Ingjerd Lien Kveldstad², Knut Mikkelsen³, Terje Veel⁴, Sven M. Almdahl⁵, Matthew H. Liang⁶, Øystein T. Førre⁷, Morten Fagerland⁸ and Ivana Hollan⁹, ¹Gjøvik University College, Gjøvik, Norway, ²Innlandet Hospital Trust, Lillehammer, Norway, ³Lillehammer Hospital for Rheumatic Diseases, Lillehammer, Norway, ⁴Feiringklinikken, Feiring, Norway, ⁵Cardiothoracic surgery, University Hospital of North Norway, Tromsø, Norway, ⁶Harvard Medical School, Boston, MA, ⁷Oslo University Hospital, Oslo, Norway, ⁸Department of Biostatistics, Oslo University Hospital, Oslo, Norway, ⁹Rheumatology, Lillehammer Hospital for Rheumatic Diseases, Lillehammer, Norway
Background/Purpose: Systemic rheumatic diseases (SRDs) are associated with increased cardiovascular (CV) morbidity due to accelerated atherosclerosis. However, SRDs are associated also with cardiac vasculitis that…
Abstract Number: 372 • 2013 ACR/ARHP Annual Meeting
Cardiovascular Risk In Intensively Treated Rheumatoid Arthritis: Comparison To An Osteoarthritis Population. First Prospective Analysis Of The ACT-CVD Cohort
Inger L. Meek¹, Harald E. Vonkeman² and Mart A.F.J. van de Laar³, ¹Rheumatology & Clinical Immunology, Rheumatology Center Twente, Medisch Spectrum Twente & Twente University, Enschede, Netherlands, ²Medisch Spectrum Twente & University of Twente, Enschede, Netherlands, ³Rheumatology, Medisch Spectrum Twente & University of Twente, Enschede, Netherlands
Background/Purpose: Rheumatoid arthritis (RA) is associated with increased cardiovascular (CV) morbidity and mortality. This association is thought to be due to the chronic inflammatory disease…
Abstract Number: 373 • 2013 ACR/ARHP Annual Meeting
Menopause Occurs Earlier and Is An Independent Risk Factor For Osteoporosis In Women With Rheumatoid Arthritis
Michael Cocker¹, Alexander Oldroyd² and Marwan Bukhari³, ¹Rheumatology, Royal Lancaster Infirmary, Lancaster, United Kingdom, ²Lancaster Medical School, Lancaster University, Lancaster, United Kingdom, ³Department of Rheumatology, Royal Lancaster Infirmary, Lancaster, United Kingdom
Background/Purpose: Rheumatoid arthritis (RA) and early menopause (
Abstract Number: 374 • 2013 ACR/ARHP Annual Meeting
Effect Of Age At Menopause In Women With Early Rheumatoid Arthritis
Lauren Wong¹, Wei-Ti Huang², Juan Xiong³, Gilles Boire⁴, Boulos Haraoui⁵, Janet E. Pope⁶, J. Carter Thorne⁷, Carol A. Hitchon⁸, Diane Tin⁹, Edward Keystone¹⁰ and Vivian P. Bykerk¹¹, ¹Rheumatology, Hospital for Special Surgery, New York, NY, ²Biostatistics, Hospital for Special Surgery, New York, NY, ³Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ⁴Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁵Rheumatology, Institut de Rhumatologie de Montréal, Montreal, QC, Canada, ⁶Medicine/Rheumatology, St. Joseph's Health Care, University of Western Ontario, London, ON, Canada, ⁷Southlake Regional Health Centre, Newmarket, ON, Canada, ⁸University of Manitoba, Winnipeg, MB, Canada, ⁹The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, ¹⁰Mount Sinai Hospital, Toronto, ON, Canada, ¹¹Divison of Rheumatology, Hospital for Special Surgery, New York, NY
Background/Purpose: Rheumatoid arthritis (RA) preferentially affects women and studies suggest that various hormonal and reproductive factors may affect disease onset and severity. This study assessed…
Abstract Number: 375 • 2013 ACR/ARHP Annual Meeting
Systemic Inflammation Contributes To Depression In Patients With Rheumatoid Arthritis
Mary Margaretten¹, Laura Trupin², Patricia P. Katz², Gabriela Schmajuk², Jinoos Yazdany², Chris Tonner², Jennifer Barton² and Edward H. Yelin³, ¹Rheumatology, University of California, San Francisco, San Francisco, CA, ²Medicine, University of California, San Francisco, San Francisco, CA, ³Arthritis Research Group, University of California, San Francisco, San Francisco, CA
Background/Purpose: Prior research suggests that systemic inflammation contributes to the pathogenesis of depression, but longitudinal studies in patients with rheumatoid arthritis (RA) are lacking. Comorbid…

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