Abstract Number: 221 • 2012 ACR/ARHP Annual Meeting
Expanding the Clinical and Serological Spectrum of MDA5-Associated Dermatomyositis
Background/Purpose: Dermatomyositis (DM) is a heterogeneous systemic disease with specific autoantibodies (Abs) which correlate with unique clinical phenotypes. Melanoma differentiation-associated gene 5 (MDA5) Abs have…Abstract Number: 222 • 2012 ACR/ARHP Annual Meeting
Lung Nodules in Patients with Idiopathic Inflammatory Myopathies
Background/Purpose: The idiopathic inflammatory myopathies are associated with an increased incidence of malignancy, and interstitial lung disease (ILD) has been reported in as many as…Abstract Number: 223 • 2012 ACR/ARHP Annual Meeting
High Prevalence and Clustering Over Time of Anti-PL-7 Autoantibody-Positive Idiopathic Inflammatory Myopathies
Background/Purpose: Unusually high prevalence of autoantibodies to threonyl tRNA (PL-7) [17% in polymyositis/dermatomyositis (PM/DM) associated with lower levels of serum creatine kinase (CK) and milder…Abstract Number: 224 • 2012 ACR/ARHP Annual Meeting
Standardized Incidence Ratios and Predictors of Malignancies in 215 Southern Chinese Patients with Inflammatory Myopathies
Background/Purpose: To examine the standardized incidence ratios (SIRs) and predictive factors for malignancy in a cohort of southern Chinese patients with inflammatory myopathies (IM). Methods:…Abstract Number: 225 • 2012 ACR/ARHP Annual Meeting
Polymyositis in HIV+ Patients Is Associated to Uncontrolled Viral Load
Background/Purpose: Different myopathies can be observed in HIV-infected patients, such as idiopathic inflammatory myopathies (inclusion-body myositis or polymyositis) or toxic mitochondrial myopathies secondary to antiretroviral…Abstract Number: 226 • 2012 ACR/ARHP Annual Meeting
Autoantibodies to Small Ubiquitin-Like Modifier Activating Enzymes in Japanese Patients with Dermatomyositis
Background/Purpose: Myositis-specific autoantibodies (MSAs) are closely associated with distinct clinical subsets within idiopathic inflammatory myopaties, and thus serve as useful diagnostic tools. Recently, anti-small ubiquitin-like modifier…Abstract Number: 187 • 2012 ACR/ARHP Annual Meeting
Effect of Colchicine On Cholesterol Levels in Patients with Familial Mediterranean Fever and Behçet’s Syndrome
Background/Purpose: We and others have previously shown that patients with Familial Mediterranean Fever (FMF) had low cholesterol levels when compared to healthy controls (1-2). The…Abstract Number: 188 • 2012 ACR/ARHP Annual Meeting
Etiology of Uveitis: A Hospital-Based Study in a Referral Centre
Background/Purpose: Defined as an intraocular inflammation, uveitis may be associated to a systemic disease or represent an isolated entity. It affects people from all parts…Abstract Number: 189 • 2012 ACR/ARHP Annual Meeting
Pedal Swelling As a Characteristic Phenotype of the New Category of Autoinflammatory Disease Associated with NOD2 Gene Mutations
Background/Purpose: Autoinflammatory diseases are characterized by seemingly unprovoked episodes of inflammation, without high titer autoantibodies or antigen specific T cells, and derive from genetic variants…Abstract Number: 190 • 2012 ACR/ARHP Annual Meeting
NLRP3 Gene Analysis for Patients with Schnitzler’s Syndrome
Background/Purpose: Schnitzler's syndrome is characterized by chronic urticaria, intermittent fever, arthralgia, bone pain, gammopathy and marked systemic inflammation. The striking response to IL-1 blockade suggests…Abstract Number: 191 • 2012 ACR/ARHP Annual Meeting
Analysis of Genes Involved in Autoinflammatory Diseases in Adult Onset Still’s Disease
Background/Purpose: Adult Onset Still’s Disease (AOSD) is a systemic inflammatory disease characterized by fever, skin rash, articular involvement, lymphadenopathy, hepatosplenomegaly and serositis. Due to the…Abstract Number: 192 • 2012 ACR/ARHP Annual Meeting
Clinical and Laboratory Findings in A Cohort of Italian Patients with Adult Onset Still’S Disease: The Role of IL-18 As A Disease Biomarker
Background/Purpose: Adult Onset Still's Disease (AOSD) is a systemic inflammatory syndrome driven by interleukin (IL)-18. Since differential diagnosis between AOSD, sepsis and other inflammatory conditions…Abstract Number: 193 • 2012 ACR/ARHP Annual Meeting
Tocilizumab in Adult Still’s Disease : The Israeli Experience
Background/Purpose: The objective of this study was to review the clinical and laboratory characteristics of patients with adult's Still disease treated with tocilizumab (TCZ) in…Abstract Number: 194 • 2012 ACR/ARHP Annual Meeting
LONG-TERM Efficacy of Tocilizumab in A Patient with Amyloidosis and Interstitial Pneumonia Secondary to Multicentric Castleman’s Disease (MCD)
Background/Purpose: Castleman’s disease is a benign lymphoproliferative disorder characterized histologically by follicular hyperplasia and capillary proliferation with endothelial hyperplasia. In addition, overproduction of Interleukin-6 (IL-6)…Abstract Number: 195 • 2012 ACR/ARHP Annual Meeting
Inflammatory Arthritis in Patients with Myelodysplastic Syndrome: French Multicenter Retrospective Study
Inflammatory arthritis in patients with myelodysplastic syndrome: French multicenter retrospective study.For the Société Nationale Française de Médecine Interne (SNFMI), the CRI (Club Rhumatismes Inflammation) and…