ACR Meeting Abstracts

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  • Abstract Number: 278 • 2012 ACR/ARHP Annual Meeting

    Evaluating Cardiovascular Risk Factors of Impaired Glucose Tolerance, Diabetes Mellitus, and Metabolic Syndrome in a Primarily Latino Population with Pediatric Rheumatic Diseases Associated with Vasculitis

    Sara M. Stern1, Jamie Wood2, Katherine AB Marzan1, Andreas Reiff1, Bracha Shaham1 and Diane Brown1, 1Division of Rheumatology, Children's Hospital Los Angeles, Los Angeles, CA, 2Division of Endocrinology, Children's Hospital Los Angeles, Los Angeles, CA

    Background/Purpose: Pediatric (PED) systemic rheumatic diseases associated with vasculitis (DAV) such as Systemic Lupus Erythematosus (SLE), Mixed Connective Tissue Disease (MCTD) and the various systemic…
  • Abstract Number: 279 • 2012 ACR/ARHP Annual Meeting

    Distribution of Vasculitides in Childhood Arthritis and Rheumatology Research Alliance-Affiliated Pediatric Rheumatology Centers in the United States

    Melissa A. Lerman1, Peter A. Merkel2 and for the CARRA Registry Investigators3, 1Division of Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA, 3Stanford, CA

    Background/Purpose: The epidemiology of pediatric vasculitis is poorly described.  Two studies in the 1990s described the frequency in pediatric rheumatology centers in the United States…
  • Abstract Number: 280 • 2012 ACR/ARHP Annual Meeting

    Pediatric Automated Neuropsychological Assessment Metrics As a Screening Tool for Neuropsychiatric Childhood-Onset Systemic Lupus Erythematosus

    Patricia Vega-Fernandez1, Eyal Muscal2, Natasha M. Ruth3, Frank Zelko4, Andrea Vincent5, Erin C. Thomas6, Marisa S. Klein-Gitelman7, Debra Canter8, Alison Tian9, Lisa Ravindra10, HaiMei Liu11, Jessica Hummel12, Deborah M. Levy13, Hermine Brunner14 and Tresa Roebuck-Spencer5, 1Pediatric Rheumatology, Cincinanti Children's Hospital Medical Center, Cincinnati, OH, 2TCH Pediatric Rheum Center, Baylor College of Medicine, Houston, TX, 3Pediatric Rheumatology, Medical University of South Carolina, Charleston, SC, 4Pediatric Neuropsychology Service, Children's Memorial Hospital, Chicago, IL, 5Cognitive Science Research Center, University of Oklahoma, Norman, OK, 6Division of Rheumatology, Anne & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, 7Division of Rheumatology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, 8Pediatric Rheumatology, Texas Children's Hospital, Houston, TX, 9Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 10University Hospital, Cincinnati, Cincinnati, OH, 11Children's Hospital of Fundan University, Shanghai, China, 12Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 13Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, 14Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Background/Purpose: Neuropsychiatric involvement appears to be common in childhood-onset systemic lupus erythematosus (cSLE), with neurocognitive dysfunction (NCD) identified in as many as 59%. NCD is…
  • Abstract Number: 281 • 2012 ACR/ARHP Annual Meeting

    The Pediatric Automated Neuropsychological Assessment Metrics – Reproducibility and Responsive to Change in Cognition in Childhood-Onset Lupus

    Patricia Vega-Fernandez1, Marisa S. Klein-Gitelman2, Jessica Hummel3, Erin C. Thomas4, Jennifer L. Huggins5, Frank Zelko6, Tresa Roebuck-Spencer7, Jun Ying8 and Hermine Brunner5, 1Division of Rheumatology, Cincinanti Children's Hospital Medical Center, Cincinnati, OH, 2Division of Rheumatology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, 3Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4Division of Rheumatology, Anne & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, 5Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 6Pediatric Neuropsychology Service, Children's Memorial Hospital, Chicago, IL, 7Center for the Study of Human Operator Performance, University of Oklahoma, Norman, OK, 8Medicine-Internal Medicine-General Medicine, University of Cincinnati, Cincinnati, OH

    Background/Purpose: The Childhood-onset Systemic Lupus Erythematosus (cSLE) Neuropsychological Battery (AC&R 2010; 62: 1029-33) was introduced to standardize neuropsychological testing (NPT), specifically probing the domains Attention,…
  • Abstract Number: 282 • 2012 ACR/ARHP Annual Meeting

    Clinical and Laboratory Features Distinguishing Juvenile Polymyositis and Muscular Dystrophy in Children

    Gulnara Mamyrova1, James D. Katz1, Robert V. Jones2, Peter A. Lachenbruch3, Mona Shah3, Olcay Y. Jones1, Anupam Chahal1, Seema Agrawal1, Frederick W. Miller3, Lisa G. Rider3 and the Childhood Myositis Heterogeneity Group4, 1Rheumatology, George Washington University, Washington, DC, 2Pathology, George Washington University, Washington, DC, 3Environmental Autoimmunity Group, NIEHS, NIH, Bethesda, MD, 4Niehs, NIH, Bethesda, MD

    Background/Purpose: We examined demographic, clinical and laboratory features of juvenile polymyositis (JPM) and muscular dystrophy in children to improve classification of these two conditions. Methods:…
  • Abstract Number: 283 • 2012 ACR/ARHP Annual Meeting

    Hospitalizations for Patients with Chilhood-Onset Systemic Lupus Erythematosus in the Pediatric Health Information System Databse

    Aimee O. Hersh1, Charlie Casper1, Tellen D. Bennett1, Susan L. Bratton1, John F. Bohnsack2 and Rajendu Srivastava1, 1Pediatrics, University of Utah, Salt Lake City, UT, 2Dept of Pediatriacs, University of Utah, Salt Lake City, UT

    Background/Purpose: To describe patient demographics, admission characteristics and clinical care for hospitalized patients with childhood-onset systemic lupus erythematous (SLE). Methods: Retrospective cohort study of the…
  • Abstract Number: 284 • 2012 ACR/ARHP Annual Meeting

    Treatment and Outcome of ANCA-Associated Vasculitis in Children: A Pilot Study

    Marinka Twilt1, Audrey Bell-Peter1, Ronald Laxer2, Christian Pagnoux3, Diane Hebert4, Elizabeth Harvey4, Shehla Sheikh2 and Susanne M. Benseler2, 1Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 2Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 3Rheumatology, Mount Sinai Hospital, Toronto, Canada, Toronto, ON, Canada, 4Nephrology, The Hospital for Sick Children, Toronto, ON, Canada

    Background/Purpose: Childhood ANCA vasculitides are rare, yet organ- or even life-threatening systemic vasculitides. Children most frequently present with rapidly evolving, severe disease such as pulmonary-renal…
  • Abstract Number: 285 • 2012 ACR/ARHP Annual Meeting

    Rituximab for Severe Disease Flares in Childhood ANCA Vasculitides

    Marinka Twilt1, Rayfel Schneider2, Audrey Bell-Peter1, Sharon Dell3 and Susanne M. Benseler4, 1Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 2Pediatric Rheumatology Collaborative Study Group (PRCSG), Cincinnati, OH, Canada, 3Respiratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada, 4Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada

    Background/Purpose: Children with ANCA vasculitides frequently present with life-threatening organ manifestations including alveolar hemorrhage, critical subglottic stenosis and renal failure due to rapidly progressive glomerulonephritis…
  • Abstract Number: 286 • 2012 ACR/ARHP Annual Meeting

    The Association of N-Methyl-D-Aspartate Receptor Antibodies and Neurocognitive Dysfunction in Pediatric Lupus Patients and in the Offspring of Adult Patients with Lupus

    Natasha M. Ruth1, Mary C. Kral2, Stephanie Slan3, Tamara K. Nowling4, Murray H. Passo1 and Gary S. Gilkeson3, 1Pediatric Rheumatology, Medical University of South Carolina, Charleston, SC, 2Genetics and Developmental Pediatrics, MUSC, Charleston, SC, 3Department of Medicine, Division of Rheumatology, Medical University of South Carolina, Charleston, SC, 4Medical University of South Carolina, Charleston, SC

    Background/Purpose: Approximately 1/5 of all systemic lupus erythematosus (SLE) starts in childhood and central nervous system (CNS) dysfunction is more common in childhood-onset SLE.  CNS…
  • Abstract Number: 287 • 2012 ACR/ARHP Annual Meeting

    Variation in Healthcare Utilization by Region and Number of Rheumatologists Per State Among Pediatric Medicaid Patients with Lupus Nephritis Prior to End-Stage Renal Disease in the United States, 2000-2004

    Linda T. Hiraki1, Candace H. Feldman2, Graciela S. Alarcon3, Jun Liu4, Michael A. Fischer5, Wolfgang C. Winkelmayer6 and Karen H. Costenbader7, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard School of Public Health, Boston, MA, 2Rheumatology, Brigham and Women's Hospital, Boston, MA, 3Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, 4Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Harvard Medical School, Boston, Boston, MA, 5Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Boston, MA, 6Division of Nephrology, Stanford University School of Medicine, Stanford, CA, 7Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Unequal healthcare access and utilization may contribute to the striking sociodemographic disparities seen in outcomes for children with lupus nephritis. Medicaid is the U.S.…
  • Abstract Number: 288 • 2012 ACR/ARHP Annual Meeting

    Validation of Promis Modules for Use in Childhood-Onset Lupus

    Alexandria J. Greenler1, Laura E. Schanberg2, Michael P. Flannery1, Shannen Nelson3, Janet Wootton4, Esi M. Morgan DeWitt3 and Hermine Brunner5, 1Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Pediatrics, Duke University Medical Center, Durham, NC, 3Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4Pediatric Rheumatology, Duke University Medical Center, Durham, NC, 5Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Background/Purpose:  The impact of childhood-onset lupus (cSLE) and its treatment on quality of life (QoL) has not been systematically established. The Patient Reported Outcomes Measurement…
  • Abstract Number: 247 • 2012 ACR/ARHP Annual Meeting

    Meager Depression Screening and Mental Health Referral Rates for Patients with Arthritis in a National Sample

    Mary Margaretten1, Patricia P. Katz2, Laura Trupin2, Gabriela Schmajuk3, Jennifer Barton4, Jinoos Yazdany5 and Edward H. Yelin6, 1Rheumatology, University of California, San Francisco, San Francisco, CA, 2Medicine, UCSF, San Francisco, CA, 3Rheumatology, UCSF / San Francisco VA Medical Center, San Francisco, CA, 4Medicine, University of California, San Francisco, San Francisco, CA, 5Rheumatology, UCSF, San Francisco, CA, 6Arthritis Research Group, UCSF, San Francisco, CA

    Background/Purpose: Depression in patients with arthritis is common and leads to poor health outcomes. While it has been shown that rheumatologists rarely communicate about depression…
  • Abstract Number: 248 • 2012 ACR/ARHP Annual Meeting

    Synovial Fluid Leptin Level Is Associated with Residual Pain and Functional Disability One Year After Total Joint Arthroplasty

    Anne Lübbeke1, Gabor J. Puskas1, Axel Finckh2, Domizio Suva1, Sylvette Bas3, Cem Gabay3, Daniel Fritschy1 and Pierre Hoffmeyer1, 1Orthopaedic Surgery, Geneva University Hospitals, Geneva, Switzerland, 2Rheumatology, Geneva University Hospitals, Geneva 14, Switzerland, 3Rheumatology, Geneva University Hospitals, Geneva, Switzerland

    Background/Purpose:  A sizeable number of patients continue to suffer from pain, functional disability and reduced quality of life after total joint arthroplasty (TJA). The etiology…
  • Abstract Number: 249 • 2012 ACR/ARHP Annual Meeting

    Medial Subchondral Bone Marrow Lesions Increase the Odds of Knee Joint Replacement – Data From the Osteoarthritis Initative

    Frank Roemer1, C. Kent Kwoh2, David Hunter3, Michael J. Hannon4, Robert M. Boudreau5, Felix Eckstein6, Zhijie Wang4, Markus R. John7 and Ali Guermazi8, 1Klinikum Augsburg, Augsburg, Germany, 2School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 3Royal North Shore Hospital, St. Leonards, Australia, 4Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, 5Epidemiology, University of Pittsburgh, Pittsburgh, PA, 6Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, 7Novartis Pharma AG, Basel, Switzerland, 8Boston University, Boston, MA

    Background/Purpose: Knee joint replacement (KR) is a cost-effective procedure with good long-term outcomes. However, there is no clear consensus on indications for KR. Subchondral bone…
  • Abstract Number: 250 • 2012 ACR/ARHP Annual Meeting

    Incident and Worsening Cartilage Damage in the Lateral Compartment and Multiple Subregions Worsening in the Medial Compartment Increase the Risk for Knee Replacement – Data From the Osteoarthritis Initiative

    Frank Roemer1, C. Kent Kwoh2, Michael J. Hannon3, Robert M. Boudreau4, Felix Eckstein5, David J. Hunter6, Zhijie Wang3, Markus R. John7 and Ali Guermazi8, 1Klinikum Augsburg, Augsburg, Germany, 2School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 3Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, 4Epidemiology, University of Pittsburgh, Pittsburgh, PA, 5Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, 6Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, 7Novartis Pharma AG, Basel, Switzerland, 8Boston University, Boston, MA

    Background/Purpose: Knee joint replacement (KR) is a cost-effective procedure with good long-term outcomes. However, at present there is no clear consensus on indications for KR.…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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