Abstracts Archive - Page 2397 of 2607 - ACR Meeting Abstracts

Abstract Number: 507 • 2013 ACR/ARHP Annual Meeting
Level Of Agreement Of The AECG 2002 and ACR 2012 Classification Criteria For Sjögren’s Syndrome In The Brittany Cohort: Clues To Understand Discrepancies
Divi Cornec¹, Alain Saraux², Jacques-Olivier Pers³, Sandrine Jousse-Joulin⁴, Yves Renaudineau³, Beatrice Cochener⁵, Thierry Marhadour⁶ and Valerie Devauchelle-Pensec⁷, ¹Department of rheumatology, Brest Occidentale University, Brest, France, ²Department of rheumatology and unit of immunology (EA 2216), CHU Brest et Université Bretagne Occidentale, Brest, France, ³Unit of immunology, EA 2216, Brest Occidentale University, Brest, France, ⁴Rheumatology, Brest university medical school, EA 2216, UBO and CHU de la Cavale Blanche,, Brest, France, ⁵Department of ophtalmology, Brest Occidentale University, Brest, France, ⁶Rheumatology, CHU de la Cavale Blanche, Brest, France, ⁷Department of rheumatology and unit of immunology (EA2216), Brest Occidentale university, Brest, France
Background/Purpose: New classification criteria for primary Sjögren’s syndrome (pSS) have been proposed in 2012 and approved by the ACR. They differ substantially from the currently…
Abstract Number: 508 • 2013 ACR/ARHP Annual Meeting
Is Ultrasonography Of Salivary Gland a Validate Tool In Sjögren Syndrome? Study 1: Interobserver Reliability Between International Group Of Experts
Sandrine Jousse-Joulin¹, Vera Milic², Elke Theander³, Malin V. Jonsson⁴, Wan-Fai Ng⁵, Chiara Baldini⁶, Marina Carotti⁷, Alan N. Baer⁸, Joel Fradin⁹, Pascale Rachele¹⁰, Hendrika Bootsma¹¹, Jacqueline Brown¹², Nicoletta Luciano⁶, S Bombardieri¹³, Roland Jonsson¹⁴, Salvatore De Vita¹⁵, Alojzija Hocevar¹⁶, Matija Tomsic^17,18, Alain Saraux¹⁹, Emmanuel Nowak²⁰, Alessandro Ciapetti Sr.²¹, Arjan Vissink²², John Rout²³, Thomas Mandl²⁴, Simon J. Bowman²⁵ and Valerie Devauchelle-Pensec²⁶, ¹Rheumatology, Brest university medical school, EA 2216, UBO and CHU de la Cavale Blanche,, Brest, France, ²rheumatology, belgrade university, belgrade, Serbia, ³Section of Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden, ⁴Department of Clinical Dentistry - Section for Oral and Maxillofacial Radiology, University of Bergen, Bergen, Norway, ⁵Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom, ⁶University of Pisa, Rheumatology Unit, Pisa, Italy, ⁷Rheumatology and radiology, Ospedali Riuniti, Ancona, Italy, ⁸Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ⁹Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, ¹⁰radiology, university of Pisa, Pisa, Italy, ¹¹Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, Groningen, Netherlands, ¹²dental division, Tower Wing Guy's hospital, london, United Kingdom, ¹³Department of Clinical and Experimental Medicine, Department of Rheumatology, University of Pisa, Pisa, Pisa, Italy, ¹⁴Broegelmann Research Laboratory, Department of Clinical Science, University of Bergen, Bergen, Norway, ¹⁵Rheumatology, DSMB, University Hospital Santa Maria della Misericordia, Udine, Italy, ¹⁶Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia, ¹⁷Department of Rheumatology, BioRx.si, University Medical Centre Ljubjana, Ljubljana, Slovenia, ¹⁸Faculty of Medicine, Unversity Ljubljana, Ljubljana, Slovenia, ¹⁹Department of rheumatology and unit of immunology (EA 2216), CHU Brest et Université Bretagne Occidentale, Brest, France, ²⁰CIC, CHU Brest, Brest, France, ²¹Department of Rheumatology, Politechnic University of the Marche, Ancona, Ancona, Italy, ²²Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Groningen, Netherlands, ²³Birmingham Dental Hospital, Birmingham, United Kingdom, ²⁴Dept of Rheumatology, Skåne University Hospital Malmo, Lund University, Sweden, Malmö, Sweden, ²⁵Department of Rheumatology, Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom, ²⁶Department of rheumatology and unit of immunology (EA2216), Brest Occidentale university, Brest, France
Background/Purpose: Ultrasonography (US) of salivary glands is a relatively new test to diagnose primary Sjögren syndrome (pSS)1-6. In 2012, an international group of interest was…
Abstract Number: 509 • 2013 ACR/ARHP Annual Meeting
A Novel Screening Tool Indicative Of Primary Sjogren’s Syndrome Versus Sicca Symptoms
Gerard Dumancas¹, Michael Brown², Indra Adrianto¹, Christopher J. Lessard¹, Jennifer A. Kelly¹, Kiely Grundahl³, Astrid Rasmussen¹, R. Hal Scofield⁴, Courtney Montgomery⁵ and Kathy L. Sivils^1,6, ¹Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ³Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, oklahoma CIty, OK, ⁴US Department of Veterans Affairs Medical Center, Oklahoma City, OK, ⁵Arthritis & Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁶Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK
Background/Purpose: Sjogren's syndrome (SS) is a chronic, progressive disease characterized by dry eyes and dry mouth resulting from lymphocytic infiltration of the lacrimal and salivary…
Abstract Number: 510 • 2013 ACR/ARHP Annual Meeting
Multicentric Analysis Of Inter and Intra Observer Reliabilities For Histopathological Abnormalities In Salivary Gland Biopsy In Primary Sjögren Syndrome
Sebastian Costa¹, Isabelle Quintin Roue², Agnes Lesourd², Sandrine Jousse-Joulin³, Pascale Marcorelles⁴, Eric Hachulla⁵, Vincent Goeb⁶, Marie-Christine Copin⁷, Jean-Marie Berthelot⁸, Jacques-Olivier Pers⁹, Olivier Vittecoq¹⁰, Emmanuel Nowak¹¹, Alain Saraux¹² and Valerie Devauchelle-Pensec¹³, ¹anatomopathological department, Brest university hospital, Brest, France, ²anatomopathological department, Morvan hospital, Brest, France, ³Rheumatology, Brest university medical school, EA 2216, UBO and CHU de la Cavale Blanche,, Brest, France, ⁴anatomopathological department, Brest university hospital, CHU Morvan, Brest, France, ⁵Internal Medicine, Lille CEDEX, France, ⁶Rheumatology, Amiens University Hospital, Amiens, France, ⁷anatomopathological department, Lille university, Lille, France, ⁸Rheumatology Unit, Nantes University Hospital, Nantes, France, ⁹Unit of immunology, EA 2216, Brest Occidentale University, Brest, France, ¹⁰Rheumatology, Rouen University Hospital & Inserm905, University of Rouen, Rouen Cedex, France, ¹¹CIC, CHU Brest, Brest, France, ¹²Department of rheumatology and unit of immunology (EA 2216), Université Brest Occidentale, Brest, France, ¹³Department of rheumatology and unit of immunology (EA2216), Brest Occidentale university, Brest, France
Background/Purpose: : Histopathologic evaluation of minor labial salivary gland (MLSG) is a major goal for the classification of patients with a primary Sjögren syndrome (pSS)…
Abstract Number: 511 • 2013 ACR/ARHP Annual Meeting
Salivary Gland Lymphocyte Pattern Associated With Response To Belimumab In Primary sjogren’ssyndrome: Results Of The Beliss Study
Raphaèle Seror¹, Thierry Lazure², Frederic Desmoulins³, Stephan Pavy⁴, Corinne Miceli-Richard⁵, Gabriel Baron⁶, Philippe Ravaud⁷ and Xavier Mariette⁸, ¹Rheumatology, Université Paris Sud, Le Kremlin Bicêtre, France, ²Pathology, INSERM U1012 - Université Paris XI, Le Kremlin Bicêtre, France, ³Rheumatology, Université Paris-Sud, Le Kremlin Bicêtre, Le Kremlin Bicetre, France, ⁴Rheumatology, Hopital Bicetre, Paris, France, ⁵Rheumatology Department, Université Paris-Sud 11, Bicêtre Hospital,, Kremlin Bicêtre, France, ⁶Hotel Dieu University Hospital Paris, Epidemiology, Paris, France, ⁷Epidemiology, Hopital Hotel Dieu, Paris Descartes University, Paris, France, ⁸Rheumatology Service, Bicêtre University Hospital, Le Kremlin Bicetre, France
Background/Purpose: To address the change in labial salivary gland (LSG) inflammation after Belimumab (biological treatment inhibiting soluble BAFF/BLyS) therapy in pSS patients and identify predictor…
Abstract Number: 512 • 2013 ACR/ARHP Annual Meeting
The Significance Of Ectopic Germinal Center In Minor Salivary Gland Of Patients With Sjögren’s Syndrome
Kyung-Eun Lee¹, Dong-Jin Park¹, Jeong-Won Lee², Ji-Hyoun Kang², Lihui Wen¹, Tae-Jong Kim³, Yong-Wook Park¹ and Shin-Seok Lee⁴, ¹Rheumatology, Chonnam National University Medical School, Gwangju, South Korea, ²Chonnam National University Medical School, Gwangju, South Korea, ³Rheumatology, Chonnam National University Medical School and Hospital, Gwangju, South Korea, ⁴Dept of Int Med/Rheumatology, Chonnam National University Medical School, Gwangju, South Korea
Background/Purpose: To investigate whether the presence of germinal center (GC) in minor salivary glands of patients with Sjögren’s syndrome (SS) is associated with different clinical…
Abstract Number: 513 • 2013 ACR/ARHP Annual Meeting
Diagnostic Value Of Labial Minor Salivary Gland Biopsy For Primary Sjögren’s Syndrome
Raquel Altoe¹, Valeria Valim², Maria Carmem S. Santos³, Erica V. Serrano¹ and Samira T. Miyamoto⁴, ¹Reumatologia, Universidade Federal do Espírito Santo, Vitória, Brazil, ²Clínica Médica - Reumatologia, Universidade Federal do Espírito Santo, Vitória, Brazil, ³Farmacologia, Universidade de Vila Velha, Vitória, Brazil, ⁴Educação Integrada em Saúde - Reumatologia, Universidade Federal do Espírito Santo, Vitoria, Brazil
Background/Purpose: The presence of lymphocytic infiltrate with ≥ 1 focus score/4mm2 in minor salivary gland is a useful tool for the diagnosis of Sjögren's syndrome…
Abstract Number: 514 • 2013 ACR/ARHP Annual Meeting
EULAR Sjögren’s Syndrome Patient Reported Index (ESSPRI) Is Increased In Sjögren’s Syndrome Patient With Fibromyalgia
Valeria Valim¹, Samira T. Miyamoto², Mauricio Paganotti³, Erica V. Serrano⁴ and Raquel Altoe⁴, ¹Clínica Médica - Reumatologia, Universidade Federal do Espírito Santo, Vitória, Brazil, ²Educação Integrada em Saúde - Reumatologia, Universidade Federal do Espírito Santo, Vitoria, Brazil, ³Farmacologia, Universidade de Vila Velha, Vitória, Brazil, ⁴Reumatologia, Universidade Federal do Espírito Santo, Vitória, Brazil
Background/Purpose: The EULAR Sjögren’s Syndrome Patient Reported Index(ESSPRI) is a patient-reported index designed to assess the severity of patients’ symptoms such as dryness, pain and…
Abstract Number: 515 • 2013 ACR/ARHP Annual Meeting
Does Multiplex Flow Immunoassay Underdetect SSA and SSB Antibodies? An Evaluation Of The Sjogren’s International Collaborative Clinical Alliance (SICCA) Cohort
Alan N. Baer¹, Laura Gutierrez², Mara McAdams DeMarco³, Mi Y. Lam⁴, Livia Casciola-Rosen⁵, Stephen Shiboski⁶, Caroline Shiboski⁴ and Lindsey A. Criswell⁷, ¹Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ²Center Tower Ste 5300, Johns Hopkins University, Baltimore, MD, ³Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, ⁴Orofacial Sciences, University of California San Francisco, San Francisco, CA, ⁵Division of Rheumatology, Johns Hopkins University, Baltimore, MD, ⁶University of California, San Francisco, San Francisco, CA, ⁷Department of Medicine, University of California, San Francisco, Rosalind Russell Medical Research Center for Arthritis, San Francisco, CA
Background/Purpose: Multiplex flow immunoassays (MFIA) are used by clinical laboratories to test for antibodies to extractable nuclear antigens. The use of blended Ro52 and…
Abstract Number: 516 • 2013 ACR/ARHP Annual Meeting
Prevalence Of Seronegative Sjogren’s Syndrome: A Comparative Study From The Sjogren’s International Collaborative Clinical Alliance (SICCA) Cohort
Alan N. Baer¹, Laura Gutierrez², Mara McAdams DeMarco³, Mi Y. Lam⁴, Livia Casciola-Rosen⁵, Stephen Shiboski⁶, Caroline Shiboski⁴ and Lindsey A. Criswell⁷, ¹Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ²Center Tower Ste 5300, Johns Hopkins University, Baltimore, MD, ³Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, ⁴Orofacial Sciences, University of California San Francisco, San Francisco, CA, ⁵Division of Rheumatology, Johns Hopkins University, Baltimore, MD, ⁶University of California, San Francisco, San Francisco, CA, ⁷Department of Medicine, University of California, San Francisco, Rosalind Russell Medical Research Center for Arthritis, San Francisco, CA
Background/Purpose: Individuals with primary Sjogren’s syndrome (SS) may lack systemic autoantibodies. When defined by the absence of anti-SSA and –SSB antibodies, the reported range…
Abstract Number: 517 • 2013 ACR/ARHP Annual Meeting
Antibody Responses To Oral Bacteria In Patients With Primary Sjögren’s Syndrome and Comparison With Rheumatoid Arthritis and Periodontitis
Bozo Lugonja¹, Michael Milward², Diana Pearson³, Thomas Dietrich⁴, Iain Chapple⁵, John Hamburger⁶, Francesca Barone¹, Saaeha Rauz⁷, Lorraine Yeo⁸, Ana Povedo-Gallego⁹, Geraint Williams⁷, Paola de Pablo¹, Andrea Richards⁹, Christopher D. Buckley¹, Dagmar Scheel-Toellner⁸ and Simon J. Bowman¹⁰, ¹Rheumatology Research Group, University of Birmingham Research Laboratories, University of Birmingham, Birmingham, United Kingdom, ²Dept of Periodontology, University of Birmingham, Birmingham, United Kingdom, ³Dept of Periodontology, Birmingham Dental Hospital, Birmingham, United Kingdom, ⁴School of Dentistry, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom, ⁵Periodontology Dept, School of Dentistry, University of Birmingham, Birmingham, United Kingdom, ⁶Dept of Oral Medicine, School of Dentistry, University of Birmingham, Birmingham, United Kingdom, ⁷Academic Unit of Ophthalmology, University of Birmingham, Birmingham, United Kingdom, ⁸Rheumatology Research Group, Centre for Translational Inflammation Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK, Birmingham, United Kingdom, ⁹Dept of Oral Medicine, Birmingham Dental Hospital, Birmingham, United Kingdom, ¹⁰Department of Rheumatology, Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom
Background/Purpose: We set out to examine peripheral blood antibody ELISA responses to common oral bacteria in primary Sjögren’s syndrome (pSS) to identify potential bacterial triggers…
Abstract Number: 518 • 2013 ACR/ARHP Annual Meeting
Vitamin D In Sjogren’s Syndrome
Suneet Grewal¹, Judith A. James², R. Hal Scofield³, Kathy L. Sivils⁴, Michael H. Weisman⁵ and Swamy Venuturupalli⁶, ¹Division of Rheumatology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, ²Oklahoma Medical Research Foundation, Oklahoma City, OK, ³Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁴Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ⁵Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁶Cedars-Sinai Medical Center, West Hollywood, CA
Background/Purpose: Unlike other autoimmune diseases in which an association with vitamin D deficiency has been established, the role of vitamin D in Sjogren’s syndrome has…
Abstract Number: 519 • 2013 ACR/ARHP Annual Meeting
Identification Of IgG4-Related Disease and Analysis Of IgG4 Serum Levels In Different Subgroups Of Patients With Sjögren’s Syndrome
Antónia Szántó¹, Gábor Nagy², Csaba Molnár³ and Margit Zeher¹, ¹Clinical Immunology, University of Debrecen, Medical and Health Science Center, Institute for Medicine, Debrecen, Hungary, ²Regional Immunological Laboratory, University of Debrecen, Medical and Health Science Center, Institute for Medicine, Debrecen, Hungary, ³University of Debrecen, Medical and Health Science Center, Institute for Pathology, Debrecen, Hungary
Background/Purpose: In the clinical diagnostic criteria of IgG4-related disease (IgG4-RD), Sjögren’s syndrome (SS) appears as one of the exclusion criteria. However, in Europe, where Mikulicz’s…
Abstract Number: 520 • 2013 ACR/ARHP Annual Meeting
Chronic Obstructive Pulmonary Disease Is Very Common in Primary Sjögren’s Syndrome
Anna M. Nilsson¹, Elke Theander², Roger Hesselstrand³, Eeva Piitulainen⁴, Sandra Diaz⁵, Olle Ekberg⁵, Per Wollmer⁶ and Thomas Mandl⁷, ¹Dept of Rheumatology, Skane University Hospital Malmo, Lund University, Malmo, Sweden, ²Section of Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden, ³Rheumatology, Lund University, Lund, Sweden, ⁴Dept of Lung medicine, Lund University & Skåne University Hospital, Malmö, Sweden, ⁵Dept of Radiology, Skåne University Hospital Malmo, Lund University, Malmö, Sweden, ⁶Dept of Clinical Physiology, Skane University Hospital Malmo, Lund University, Malmö, Sweden, ⁷Dept of Rheumatology, Skåne University Hospital Malmo, Lund University, Sweden, Malmö, Sweden
Background/Purpose: To study the prevalence of chronic obstructive pulmonary disease (COPD) in patients with primary Sjögren's syndrome (pSS) and its association with respiratory symptoms, pulmonary…
Abstract Number: 498 • 2013 ACR/ARHP Annual Meeting
A Systematic Review and Meta-Analysis Comparing Low- Versus High-Dose Rituximab For Rheumatoid Arthritis
Markus Bredemeier, Fernando K. de Oliveira and Claúdia M. Rocha, Rheumatology, Hospital Nossa Senhora da Conceição - Grupo Hospitalar Conceição, Porto Alegre, Brazil
Background/Purpose: The approved dose of rituximab (RTX) for rheumatoid arthritis (RA) is 2x1000 mg infusions given 2 weeks apart. There is contradictory evidence regarding the…

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