Abstracts Archive - Page 2391 of 2607 - ACR Meeting Abstracts

Abstract Number: 618 • 2013 ACR/ARHP Annual Meeting
Active Renal Disease Is Associated With The Presence Of The Metabolic Syndrome (MetS) In Peruvian Patients With Systemic Lupus Erythematosus (SLE)
Manuel F. Ugarte-Gil^1,2, Rocio V. Gamboa-Cardenas³, Mariela Medina-Chinchon¹, Francisco Zevallos-Miranda¹, Karim E. Diaz-Deza³, J. Mariano Cucho-Venegas¹, Zoila Rodriguez-Bellido^1,4, Jose L. Alfaro-Lozano¹, Risto A. Perich-Campos^1,4, Erika Noriega³, Hugo Torrealva¹ and Cesar A. Pastor-Asurza^1,4, ¹Rheumatology, Hospital Guillermo Almenara, EsSalud, Lima, Peru, ²Universidad Cientifica del Sur, Lima, Peru, ³Rheumatology, Hospital Almenara, Lima, Peru, ⁴Universidad Nacional Mayor de San Marcos, Lima, Peru
Background/Purpose: The MetS prevalence is increased in SLE patients, in particular in those of Hispanic origin and it is associated with a higher risk for…
Abstract Number: 619 • 2013 ACR/ARHP Annual Meeting
Survival and Prognostic Factors In Patients With Connective Tissue Disease Associated Pulmonary Arterial Hypertension: Results From Korean Nationwide Registry
Kwi Young Kang¹, Chan Hong Jeon², Sung Jae Choi³, Seung-Ki Kwok⁴, Seong-Kyu Kim⁵, Hyoun-Ah Kim⁶, Eon Jeong Nam⁷, Yong-Beom Park⁸, Kichul Shin⁹, Jaejoon Lee¹⁰, Chang-Hoon Lee¹¹, Chan-Bum Choi¹², Shin-Seok Lee¹³ and Dae-Hyun Yoo¹⁴, ¹Rheumatology, Internal Medicine, Catholic University of Korea, Incheon St. Mary's Hospital, Seoul, South Korea, ²Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, South Korea, ³Rheumatology, Korea University Medical Center, Seoul, South Korea, ⁴Division of Rheumatology, Department of Internal Medicine, School of Medicine, The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, South Korea, ⁵Catholic University of Daegu School of Medicine, Daegu, South Korea, ⁶Department of Rheumatology, Ajou University School of Medicine, Suwon, South Korea, ⁷Internal Medicine (Rheumatology), Kyungpook National University School of Medicine, Daegu, South Korea, ⁸Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea, ⁹Rheumatology, College of Medicine, Seoul National University, Seoul, South Korea, ¹⁰Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, ¹¹Department of Internal Medicine, School of Medicine, Wonkwang University, Iksan, Chonbuk, South Korea, ¹²Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Clinical Research Center for Rheumatoid Arthritis (CRCRA), Seoul, South Korea, ¹³Dept of Int Med/Rheumatology, Chonnam National University Medical School, Gwangju, South Korea, ¹⁴Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea
Background/Purpose: Pulmonary arterial hypertension (PAH) is a major cause of mortality in connective tissue disease (CTD). We sought to quantify survival and determine factors predictive…
Abstract Number: 620 • 2013 ACR/ARHP Annual Meeting
Human Papillomavirus and Precancerous Lesions In Patients With Systemic Lupus Erythematosus
Eleonora Lucero¹, Laura Juarez¹, Veronica Bellomio¹, Francisco Colombres², Maximiliano Machado Escobar¹, Raúl Nicolás Martínez¹, Teresita Alvarellos³, Agustina Lacaze³, Ariel Sanchez⁴, Pablo Agustín Apas Perez de Nucci⁵, Guillermo Cohen Imach⁵, Sonia Marcela Ortiz Mayor⁶, Iris Aybar Odstrcil⁶, Ana Cerón⁶, Ricardo V. Juárez⁷, Mirta Santana⁸ and Alberto Berman¹, ¹Rheumatology Unit, Padilla Hospital, Tucumán, Argentina, ²Centro Medico Privado de Reumatologia, Tucumán, Argentina, ³Biological Molecular Laboratory, Córdoba Private Hospital, Córdoba, Argentina, ⁴Biological Molecular Unit, Córdoba Private Hospital, Córdoba, Argentina, ⁵Ginecology Unit, Padilla Hospital, Tucumán, Argentina, ⁶Pathology Unit, Padilla Hospital, Tucumán, Argentina, ⁷Rheumatology Section, Hospital Señor del Milagro, Salta, Argentina, ⁸Padilla Hospital, Tucumán, Argentina
Background/Purpose: To evaluate the presence of Precancerous Lesions (PL) in uterine cervix in patients with Systemic Lupus Erythematosus (SLE) and its relationship with Human Papillomavirus…
Abstract Number: 621 • 2013 ACR/ARHP Annual Meeting
Baseline Characteristics That Predict a Short-Term Response To Immunosuppressive Treatment In Patients With Pulmonary Arterial Hypertension Associated With Connective Tissue Disease
Hidekata Yasuoka¹, Yuichiro Shirai¹, Yuichi Tamura², Toru Satoh³, Tsutomu Takeuchi¹ and Masataka Kuwana¹, ¹Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, ²Department of Cardiology, Keio University School of Medicine, Tokyo, Japan, ³Department of Cardiology, Kyorin University School of Medicine, Tokyo, Japan
Background/Purpose: Pulmonary arterial hypertension (PAH) is one of devastating organ involvements in patients with connective tissue diseases (CTDs). Recent introduction of molecular-targeting PAH drugs, such…
Abstract Number: 591 • 2013 ACR/ARHP Annual Meeting
Elevated Level Of cfDNA Mainly Derive From Netosis Of Common Neutrophils As Well As Low-Density Granulocytes In Systemic Lupus Erythematosus and Is Associated With Lupus Nephritis Severity
Sigong Zhang¹, Guochun Wang² and Xin Lu², ¹Department of Rheumatology,, China-Japan Friendship Hospital, Beijing, China, Beijing, China, ²Department of Rheumatology, China-Japan Friendship Hospital, Beijing, China, Beijing, China
Background/Purpose: Insufficient clearance of neutrophil extracellular traps (NETs) has been involved in lupus nephritis and can cause the increase of residual NETs in vivo, which…
Abstract Number: 598 • 2013 ACR/ARHP Annual Meeting
Gender Influence On Lupus Nephritis Outcomes In An Urban, Multiethnic Population
Cindy Johnston, Catarina Vila-Inda and Irene Blanco, Rheumatology, Albert Einstein College of Medicine, Bronx, NY
Background/Purpose: Systemic lupus erythematosus (SLE) is a disease predominately of young women that disproportionately affects minorities. Lupus Nephritis (LN) causes major morbidity and mortality in…
Abstract Number: 582 • 2013 ACR/ARHP Annual Meeting
A Real-World Survey Of Clinical Practice Among Rheumatologists and Nephrologists In The United States Reveals Differences In Care Of Non-Nephritis Systemic Lupus Erythematosus and Lupus Nephritis As Compared With American College Of Rheumatology Treatment Guidelines
Neelufar Mozaffarian¹, Steve Lobosco² and Adam Roughley², ¹AbbVie, North Chicago, IL, ²Adelphi Real World Ltd., Macclesfield, United Kingdom
Background/Purpose: Current pharmacotherapy for systemic lupus erythematosus (SLE) and lupus nephritis (LN) includes combinations of nonsteroidal anti–inflammatory drugs (NSAIDs), antimalarials (AMs), glucocorticoids (GCs), and cytotoxic…
Abstract Number: 583 • 2013 ACR/ARHP Annual Meeting
Prognostic Significance Of Visit-To-Visit Variability, Maximum Systolic Blood Pressure, and Episodic Hypertension In Sytemic Lupus Erythematosus
George Stojan¹, Hong Fang², Laurence S. Magder³ and Michelle Petri², ¹Div of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ²Johns Hopkins University School of Medicine, Baltimore, MD, ³Department of Epidemiology and Public Health, University of Maryland, Baltimore, MD
Background/Purpose: SLE is considered a coronary heart disease equivalent and aggressive management of all traditional risk factors is recommended. Hypertension is a major problem in…
Abstract Number: 584 • 2013 ACR/ARHP Annual Meeting
The Effect Of Ramipril On Endothelial Function and Endothelial Progenitor Cells In Patients With Systemic Lupus Erythematosus
Emilia I. Sato¹, Luiz Samuel G. Machado² and Ana Cecilia Machado³, ¹Rheumatology Div/Dept of Med, Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil, ²Rheumatology, Universidade Federal de São Paulo, São Paulo, Brazil, ³Medicina, Universidade Federal de São Paulo, São Paulo, Brazil
Background/Purpose: Cardiovascular diseases (CVD) are one of major causes of morbidity and mortality in SLE patients. Traditional cardiovascular risk factors and disease intrinsic factors contribute…
Abstract Number: 585 • 2013 ACR/ARHP Annual Meeting
Breast Cancer In Systemic Lupus (SLE): Do Demographic and Clinical Factors, Including DNA serology, Influence Risk?
Sasha Bernatsky¹, Rosalind Ramsey-Goldman², Michelle Petri³, Murray B. Urowitz⁴, Dafna D. Gladman⁵, Christine Peschken⁶, William Foulkes¹, Yvan St. Pierre⁷, Patrice Chrétien Raymer⁷, Basile Tessier Cloutier⁸, Guillermo Ruiz-Irastorza⁹, Ann E. Clarke¹ and Systemic Lupus International Collaborating Clinics (SLICC)¹⁰, ¹McGill University, Montreal, QC, Canada, ²Medicine/Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Johns Hopkins University School of Medicine, Baltimore, MD, ⁴Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁵Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ⁶Medicine & Community Health Sciences, University of Manitoba, Winnipeg, MB, Canada, ⁷Clinical Epidemiology, McGill University Health Centre, Montreal, QC, Canada, ⁸Clinical Epidemiology, McGill University, Montreal, QC, Canada, ⁹Autoimmune Diseases Research Unit, Department of Internal Medicine, BioCruces Health Research Institute, Hospital Universitario Cruces, University of the Basque Country, Barakaldo, Spain, ¹⁰(coordinating centre), Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: There is an increase in cancer in SLE over-all, but decrease in other cancers, such as breast cancer. Of particular interest are autoantibodies targeting…
Abstract Number: 586 • 2013 ACR/ARHP Annual Meeting
Blood Pressure Variability and Age-Related Blood Pressure Patterns In Systemic Lupus Erythematosus
George Stojan¹, Laurence S. Magder² and Michelle Petri³, ¹Div of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ²Department of Epidemiology and Public Health, University of Maryland, Baltimore, MD, ³Johns Hopkins University School of Medicine, Baltimore, MD
Background/Purpose: Increased visit-to-visit blood pressure (BP) variability has been associated with an increased risk of all-cause mortality, stroke, left ventricular diastolic dysfunction, and cognitive impairment…
Abstract Number: 587 • 2013 ACR/ARHP Annual Meeting
Low-Dose Aspirin Has An Anti-Platelet Effect In Systemic Lupus Erythematosus
Michelle Petri¹, Laurence S. Magder² and Thomas Kickler¹, ¹Johns Hopkins University School of Medicine, Baltimore, MD, ²Department of Epidemiology and Public Health, University of Maryland, Baltimore, MD
Background/Purpose: Thrombosis is increased in SLE patients, with and without antiphospholipid antibodies. Aspirin and hydroxychloroquine are thought to have anti-platelet effects. We determined whether these…
Abstract Number: 588 • 2013 ACR/ARHP Annual Meeting
Efficacy Of Rituximab In Patients With Refractory Lupus Nephritis, a Post-Hoc Analysis From Phase II Trial In Japan
Yoshiya Tanaka¹, Kazuhiko Yamamoto², Tsutomu Takeuchi³, Nobuyuki Miyasaka⁴, Takayuki Sumida⁵, Tsuneyo Mimori⁶, Takao Koike⁷ and Kazuhiro Endo⁸, ¹The First Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan, ²Department of Allergy and Rhaumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, ³Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, ⁴Tokyo Medical and Dental University, Tokyo, Japan, ⁵Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan, ⁶Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, ⁷Rheumatology, NTT Sapporo Medical Center, Sapporo, Japan, ⁸Clinical Development, Zenyaku Kogyo Co., Ltd., Tokyo, Japan
Background/Purpose: B-cell depletion therapy by rituximab has been reported to be useful for treatment of lupus nephritis (LN) in many observational uncontrolled studies, however, placebo-controlled…
Abstract Number: 589 • 2013 ACR/ARHP Annual Meeting
A Survey Of Physician and Patient Satisfaction With Control Of Systemic Lupus Erythematosus and Lupus Nephritis
Neelufar Mozaffarian¹, Steve Lobosco² and Adam Roughley², ¹AbbVie, North Chicago, IL, ²Adelphi Real World Ltd., Macclesfield, United Kingdom
Background/Purpose: Patient satisfaction with disease control is an important component of overall health and well-being. Current treatment options for systemic lupus erythematosus (SLE) ±lupus nephritis…
Abstract Number: 590 • 2013 ACR/ARHP Annual Meeting
Candidate Urinary Biomarkers May Predict The Future Development Of Renal Functional Loss With Lupus Nephritis In Children and Adults
Khalid Abulaban¹, Brad H. Rovin², Shannen Nelson³, Huijuan Song⁴, Paul Kimmel⁵, John Kusek⁶, Harold Feldman⁷, Vasan Ramachandran⁸, Michael Bennett⁹, Jun Ying¹⁰ and Hermine Brunner¹¹, ¹Pediatric Rheumatology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, ²Division of Nephrology, Ohio State University Medical Center, Columbus, OH, ³Rheumatology, Cincinnati Children's Hospital, Cincinnati, OH, ⁴Ohio State University Medical Center, Columbus, OH, ⁵DIVISION OF KIDNEY, UROLOGIC, & HEMATOLOGIC DISEASES, NIDDK, National Institutes of Health, Bethesda, MD, ⁶NIDDK, National Institutes of Health, Bethesda, MD, ⁷The University of Pennsylvania, Philadelphia, PA, ⁸Section of Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, MA, ⁹Nephrology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, ¹⁰Medicine-Internal Medicine-General Medicine, University of Cincinnati, Cincinnati, OH, ¹¹Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose: Lupus nephritis(LN) is frequently associated with a poor long-term prognosis. Current non-invasive blood and urine tests do not reliably predict the course of LN.…

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