Abstracts Archive - Page 2385 of 2425 - ACR Meeting Abstracts

Abstract Number: 570 • 2012 ACR/ARHP Annual Meeting
Randomized Controlled Trial of Adalimumab in Patients with Peripheral Spondyloarthritis
Philip J. Mease¹, Joachim Sieper², Filip Van den Bosch³, Proton Rahman⁴, Katie Obermeyer⁵ and Aileen L. Pangan⁵, ¹Rheumatology Research, Swedish Medical Center, Seattle, WA, ²Medical Department I, Rheumatology, Charité Universitätesmedizin Berlin, Berlin, Germany, ³Rheumatology, Ghent University Hospital, Ghent, Belgium, ⁴Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, ⁵Abbott Laboratories, Abbott Park, IL
Background/Purpose: Adalimumab (ADA) is indicated for the treatment of psoriatic arthritis (PsA) and ankylosing spondylitis (AS). Patients (pts) with peripheral spondyloarthritis (SpA) not previously diagnosed…
Abstract Number: 530 • 2012 ACR/ARHP Annual Meeting
S100A8/A9 Is Upregulated and Triggers the Secretion of Pro-Inflammatory Cytokines in Primary Sjögren’s Syndrome
Laura Weichselbaum¹ and Muhammad S. Soyfoo², ¹Rheumatology, Department of rheumatology ,Hôpital Erasme, Brussels, Belgium, ²Rheumatology, Hôpital Erasme,Université Libre de Bruxelles, Brussels, Belgium
Background/Purpose: To determine the involvement of S100A8/A9 in the pathogenesis of primary Sjögren’s syndrome (pSS) Methods: The serum levels of S100A8/A9, IL-17A and IL-17C were…
Abstract Number: 531 • 2012 ACR/ARHP Annual Meeting
Developmen and Validation of a New Instrument to Asess Health Related Quality of Life in Psoriasis Arthritis: The Vitacora Questionnaire
Juan Carlos Torre-Alonso¹, J. Santos-Rey², JM Ruiz-Martin³, P. Valdazo-De Diego⁴, Mireia Moreno⁵ and Juan-Antonio Fernández⁶, ¹Unit Rheumatology, Hospital Monte Naranco, Oviedo, Spain, ²Rheumatology, Toledo, Spain, ³Rheumatology, Viladecans, Spain, ⁴Rheumatology, Zamora, Spain, ⁵Rheumatology, Corporació Sanitària Parc Taulí, Sabadell, Spain, ⁶MP, Oviedo, Spain
Background/Purpose: To develop and validate a specific questionnaire to measure health-related quality of life (HRQoL) in adults with psoriasis arthritis (PA) for use in clinical…
Abstract Number: 532 • 2012 ACR/ARHP Annual Meeting
The Prevalance of Autoimmune Thyroid Disfunction in Ankylosing Spondylitis
Hakan Emmungil¹, Mehmet Erdogan², Melike Kalfa¹, Gonca Karabulut¹, Hayriye Kocanaogullari¹, Vedat Inal¹, Yasemin Kabasakal³, Fahrettin Oksel⁴, Kenan Aksu⁵ and Gokhan Keser⁶, ¹Dept. of Internal Medicine, Division of Rheumatology, Ege University, Dept. of Internal Medicine, Division of Rheumatology, Ege University, Izmir, Turkey, ²Dept. of Internal Medicine, Division of Endocrinolgy, Ege University, Dept. of Internal Medicine, Division of Endocrinolgy, Ege University, Izmir, Turkey, ³Dept. of Internal Medicine, Division of Rheumatology, Ege University, Izmir, Turkey, ⁴Division of Rheumatology, Ege University, Izmir, Turkey, ⁵Dept. Of Internal Medicine, Division of Rheumatology, Ege University, Dept. Of Internal Medicine, Division of Rheumatology, Ege University, Izmir, Turkey, ⁶Dept. of Internal Medicine, Division of Rheumatology, Dept. of Internal Medicine, Division of Rheumatology, Ege University, Izmir, Turkey
Background/Purpose: Although the association of autoimmune thyroid dysfunction and primary Sjögren's syndrome (SjS) is well known, it is less clear whether a similar relationship also…
Abstract Number: 533 • 2012 ACR/ARHP Annual Meeting
NT-Probnp and Inflammation in Active Ankylosing Spondylitis Receiving TNF Blockers: Is There a Link?
Julio C. B. Moraes¹, Ana C. M. Ribeiro², Carla G.S. Saad³, Alessandro C. Lianza⁴, Nadia E. Aikawa⁵, Clovis Artur Silva⁶ and Eloisa Bonfa⁷, ¹Reumatologia, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ²Rheumatology, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, ³Rheumatology Division, University of Sao Paulo, Sao Paulo, Brazil, ⁴Radiology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁵Rheumatology, University of São Paulo, Sao Paulo, Brazil, ⁶Paediatric Rheumatology International Trials Organization (PRINTO), Istituto Giannina Gaslini, Genova, Italy, ⁷Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: Cardiovascular disease plays a central role in morbidity and mortality in rheumatic patients. N-terminal pro-brain natriuretic peptide (NT-proBNP) is a strong marker of cardiovascular…
Abstract Number: 535 • 2012 ACR/ARHP Annual Meeting
Reduced Joint Counts Misclassify Psoriatic Arthritis Patients with Oligoarthritis and Miss Significant Active Disease
Laura C. Coates¹, Oliver FitzGerald², Dafna D. Gladman³, Neil J. McHugh⁴, Philip J. Mease⁵, Vibeke Strand⁶, Philip S. Helliwell⁷ and GRAPPA Composite Exercise (GRACE) collaboration⁸, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ²Dept of Rheumatology, St. Vincent's Univ Hospital, Dublin, Ireland, ³Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁴Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, ⁵Rheumatology Research, Swedish Medical Center, Seattle, WA, ⁶Adjunct, Division of Immunology / Rheumatology, Stanford University, Portola Valley, CA, ⁷PsAID taskforce, EULAR, Zurich, Switzerland, ⁸Leeds
Background/Purpose: Despite recommendations to use full joint counts to assess patients with PsA, reduced joint counts designed for RA are often used for reporting outcomes…
Abstract Number: 536 • 2012 ACR/ARHP Annual Meeting
Psoriasis and Psoriatic Arthritis in a Diverse Ethnic Cohort
Gail S. Kerr¹, Seema Qaiyumi², John S. Richards², Chesahna Kindred³, Sean A. Whelton⁴ and Florina M. Constantinescu⁵, ¹Rheumatology, Washington DC VAMC, Georgetown and Howard University, Washington, DC, ²Rheumatology Section, Washington DC VA and Georgetown University, Washington, DC, ³Division of Dermatology, Howard University Hospital, Washington, DC, ⁴Division of Rheumatology, Georgetown University, Washington, DC, ⁵Rheumatology, Washington Hospital Center, Washington, DC
Background/Purpose: Few clinical studies describe psoriasis (PSO) and psoriatic arthritis (PsA) in ethnic minority groups. Previous patient-reported data show PSO/PsA to be less frequent in…
Abstract Number: 537 • 2012 ACR/ARHP Annual Meeting
The Association of alpha7 Nicotinic Acetylcholine Receptor Polymorphisms with Psoriatic Arthritis and Its Interaction with Smoking
Lihi Eder¹, Vinod Chandran², Fawnda Pellett³, Remy Pollock⁴, Fatima Abji⁵, Adele Carty⁶, Sutharshini Shanmugarajah⁵, Cheryl Rosen⁷ and D. D. Gladman⁸, ¹Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ³Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁴Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ⁵Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ⁶Rheumatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, ⁷Division of Dermatology, University of Toronto, Toronto western Hospital, Toronto, ON, Canada, ⁸Division of Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada
Background/Purpose: Alpha7 nicotinic acetylcholine receptor (CHRNA7) is an ion channel that is gated by the binding of nicotinic ligands. Nicotine interacts with CHRNA7 leading to…
Abstract Number: 538 • 2012 ACR/ARHP Annual Meeting
Association Between Biomarkers (Metalloproteinase-3, Dikkopf-1 and Sclerostin) with Disease Activity and Prediction of Anti-TNFá Therapy Response in Patients with Ankylosing Spondylitis
Victoria Navarro-Compán¹, Rafael Ariza², Rufino Mondéjar-García³, Virginia Moreira-Navarrete⁴, Enrique Melguizo-Madrid³, Blanca Hernández-Cruz⁴, Concepción González-Rodríguez³ and Federico Navarro-Sarabia⁵, ¹Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, University Hospital Virgen Macarena.Sevilla, Sevilla, Spain, ³Biochemistry, University Hospital Virgen Macarena, Sevilla, Spain, ⁴Rheumatology, University Hospital Virgen Macarena, Sevilla, Spain, ⁵Rheumatology, Hospital Virgen Macarena, Serv. de Reumatología, Sevilla, Spain
Background/Purpose: Better objectives measures for evaluating disease activity and anti-TNFα response in patients with ankylosing spondylitis (AS) are needed. MMP-3 seems to be the most…
Abstract Number: 539 • 2012 ACR/ARHP Annual Meeting
Efficacy and Safety of Adalimumab for the Treatment of Peripheral Arthritis in Spondyloarthritis Patients without Ankylosing Spondylitis or Psoriatic Arthritis
Jacqueline E. Paramarta¹, Leen De Rycke², Tanja F. Heijda², Carmen A. Ambarus³, Koen Vos², Huib J. Dinant², Paul P. Tak² and Dominique L. Baeten², ¹Department of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, ²Division of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, ³Department Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands
Background/Purpose: The treatment of spondyloarthritis (SpA) has improved dramatically since the introduction of TNF-blockade. However, this therapy is only approved and reimbursed for the treatment…
Abstract Number: 540 • 2012 ACR/ARHP Annual Meeting
The Predictors of Reduced Work Productivity in Patients with Psoriatic Arthritis
Anjali Papneja¹, Matthew Kennedy², Arane Thavaneswaran³, Daniel Pereira⁴, Vinod Chandran⁵ and Dafna D. Gladman⁶, ¹Rheumatology, University of Toronto, Toronto, ON, Canada, ²Medicine, University of Toronto, TOronto, ON, Canada, ³Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁴Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ⁵University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁶Toronto Western Hospital and University of Toronto, Toronto, ON, Canada
Background/Purpose: Psoriatic arthritis (PsA) is a unique inflammatory musculoskeletal disorder associated with psoriasis. Related to its detrimental impact on health and quality of life, PsA…
Abstract Number: 541 • 2012 ACR/ARHP Annual Meeting
Prevalence of Sacroiliitis in the General Population: Comparative Analysis with Cutaneous Psoriasis and Psoriatic Arthritis
Jose Luis Fernandez-Sueiro¹, Carlos Fernandez-Lopez², S. Pertega-Diaz³, JA Pinto¹, E. Gonzalez², Francisco J. de Toro-Santos⁴ and Francisco J. Blanco V⁵, ¹Rheumatology Division, Complejo Hospitalario Universitario La Coruña, La Coruña, Spain, ²Rheumatology, Complejo Hospitalario Universitario La Coruña, La Coruña, Spain, ³Epidemiology and Statistics, Complejo Hospitalario Universitario La Coruña, La Coruña, Spain, ⁴Reumatology Division, Complejo Hospitalario Universitario La Coruña, La Coruña, Spain, ⁵Rheumatology Service, INIBIC-Hospital Universitario A Coruña, A Coruña, Spain
Background/Purpose: At least grade 2 unilateral sacroiliitis in the presence of spinal symptoms (defined as a combination of inflammatory back pain plus back stiffness) in…
Abstract Number: 542 • 2012 ACR/ARHP Annual Meeting
Validation of a Reference Imaging Module for Calibration of Readers Scoring with the Modified Stoke Ankylosing Spondylitis Spine Score
Walter P. Maksymowych¹, Thomas J. Learch², Robert GW Lambert³, Michael M. Ward⁴, Nigil Haroon⁵, David Salonen⁶, Robert D. Inman⁷ and Michael H. Weisman⁸, ¹Department of Medicine, University of Alberta, Edmonton, AB, Canada, ²Cedars-Sinai, Los Angeles, CA, ³Radiology, University of Alberta, Edmonton, AB, Canada, ⁴Bldg 10 CRC Rm 4-1339, NIAMS/NIH, Bethesda, MD, ⁵Medicine/Rheumatology, University Health Network, Toronto Western Research Institute, University of Toronto, Toronto, ON, Canada, ⁶Department of Medical Imaging, University Health Network, Toronto, ON, Canada, ⁷Dept of Medicine/Rheumatology, Toronto Western Research Institute, University Health Network and University of Toronto, Toronto, ON, Canada, ⁸Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA
Background/Purpose: The modified Stoke Ankylosing Spondylitis Spine Score (mSASSS) is used to assess progression in AS based on the lateral spinal radiograph but the methodology…
Abstract Number: 543 • 2012 ACR/ARHP Annual Meeting
Wnt Pathway Inhibitors in Patients with Psoriatic and Rheumatoid Arthritis Treated with Anti-TNF Therapy
Agnes Szentpetery¹, Harjit P. Bhattoa², Peter Antal-Szalmas², Zoltan Szekanecz³ and Oliver M. FitzGerald⁴, ¹Rheumatology, Department of Rheumatology, St. Vincent's University Hospital, Dublin, Ireland, ²Laboratory Medicine, Department of Laboratory Medicine, University of Debrecen, Medical and Health Science Center, Debrecen, Hungary, ³Rheumatology, Department of Rheumatology, University of Debrecen Medical and Health Sciences Center, Debrecen, Hungary, ⁴Rheumatology, Dublin Academic Medical Centre, St. Vincent's University Hospital, Dublin, Ireland
Background/Purpose: Both rheumatoid arthritis (RA) and psoriatic arthritis (PsA) are characterised by bone erosion but aberrant bone formation is also a feature in PsA. Wnt…
Abstract Number: 544 • 2012 ACR/ARHP Annual Meeting
Anterior Chest Wall Pain in Recent Inflammatory Back Pain. Data From the DESIR Cohort
Daniel Wendling¹, Clément Prati², Christophe Demattei³, Damien Loeuille⁴, P. Richette⁵ and Maxime Dougados⁶, ¹Service de Rhumatologie, Minjoz University Hospital, Besancon, France, ²Service de Rhumatologie, CHU J Minjoz, Besancon, France, ³Service BESPIM, CHU, Nimes, France, ⁴Rheumatology, CHU Brabois, Vandoeuvre les Nancy, France, ⁵Centre Viggo Petersen / Service de Rhumatologie, Hôpital Lariboisière, Paris, France, ⁶Rheumatology B Department, Paris-Descartes University, APHP, Cochin Hospital, Paris, France
Background/Purpose: Anterior chest wall pain (ACW) may be suggestive of spondyloarthritis (SpA), but little is known about this clinical feature in recent inflammatory back pain…

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