Abstracts Archive - Page 2384 of 2425 - ACR Meeting Abstracts

Abstract Number: 555 • 2012 ACR/ARHP Annual Meeting
Performances of the ASAS Axial Spondyloarthritis Criteria for Diagnosis and Classification Purposes in Patients Visiting a Rheumatologist Because of Chronic Back Pain: The Declic Study
Anna Moltó¹, Simon Paternotte², Denis Comet³, Cécile Hacquard-Bouder⁴, Martin Rudwaleit⁵, Pascal Claudepierre⁶, Désirée van der Heijde⁷ and Maxime Dougados¹, ¹Rheumatology B Department, Paris-Descartes University, APHP, Cochin Hospital, Paris, France, ²Rheumatology Department, Paris- Descartes University, Cochin hospital, Paris, France, ³Axonal, Nanterre, France, ⁴Abbott France, Rungis, France, ⁵Endokrinologikum Berlin, Berlin, Germany, ⁶Rheumatology, Henri Mondor Teaching Hospital, AP-HP, Créteil, France, ⁷Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: To evaluate the performances at diagnosis (sensitivity [Se], specificity [Spe], positive and negative predictive values) and study visit (classification purpose) of the ASAS criteria…
Abstract Number: 556 • 2012 ACR/ARHP Annual Meeting
Eos Imaging Could Replace Conventional Computed Radiography for Ankylosis Assessment in Axial Spondyloarthritis
Anna Moltó¹, Veronique Freire², Antoine Feydy³, Simon Paternotte¹, Walter P. Maksymowych⁴, Mathilde Benhamou⁵, François Rannou⁵, Maxime Dougados¹ and Laure Gossec¹, ¹Rheumatology B Department, Paris-Descartes University, Cochin Hospital, Paris, France, ²Radiology B Department, Paris Descartes University, Cochin Hospital, APHP, Paris, France, Paris, France, ³Radiology B, Paris Descartes University, Côchin Hospital, APHP, Paris, France, ⁴Department of Medicine, University of Alberta, Edmonton, AB, Canada, ⁵Physical Medicine and Rehabilitation Service, Paris-Descartes University, Cochin Hospital, Paris, France
Background/Purpose: EOS® is a new osteoarticular imaging modality with significantly lower radiation than conventional computed radiography (CR). However, the diagnostic performance of this 2D biplanar…
Abstract Number: 557 • 2012 ACR/ARHP Annual Meeting
Effect of Certolizumab Pegol On the Multiple Facets of Psoriatic Arthritis As Reported by Patients: 24 Week Patient Reported Outcome Results of a Phase 3 Double Blind Randomized Placebo-Controlled Study
Dafna D. Gladman¹, Roy Fleischmann², Geoffroy Coteur³, Franz Woltering⁴ and Philip J. Mease⁵, ¹Centre for Prognosis Studies in The Rheumatic Diseases, Toronto Western Research Institute, University of Toronto, University Health Network, Toronto, ON, Canada, ²University of Texas Southwestern Medical Center at Dallas, Dallas, TX, ³UCB Pharma, Brussels, Belgium, ⁴UCB Pharma, Monheim, Germany, ⁵Seattle Rheumatology Associates, Seattle, WA
Background/Purpose: RAPID-PsA (NCT01087788) reports efficacy and safety of certolizumab pegol (CZP), a PEGylated Fc-free anti-TNF, in psoriatic arthritis (PsA).1 The effect of different imputation methodologies…
Abstract Number: 558 • 2012 ACR/ARHP Annual Meeting
Rapid Improvements in Patient Reported Outcomes with Certolizumab Pegol in Patients with Axial Spondyloarthritis, Including Ankylosing Spondylitis and Non-Radiographic Axial Spondyloarthritis: 24 Week Results of a Phase 3 Double Blind Randomized Placebo-Controlled Study
Joachim Sieper¹, Alan J. Kivitz², A.M. Van Tubergen³, Atul A. Deodhar⁴, Geoffroy Coteur⁵, Franz Woltering⁶ and Robert B. M. Landewé⁷, ¹Medical Department I, Rheumatology, Charité University Medicine, Berlin, Germany, ²Altoona Center for Clinical Research, Duncansville, PA, ³Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands, ⁴Oregon Health & Science University, Portland, OR, ⁵UCB Pharma, Brussels, Belgium, ⁶UCB Pharma, Monheim, Germany, ⁷Department of Rheumatology, Amsterdam Rheumatology Center, Amsterdam, Netherlands
Background/Purpose: Axial spondyloarthritis (axSpA) is a form of spondyloarthritis (SpA) that includes both ankylosing spondylitis (AS) and non-radiographic axial SpA (nr-axSpA), as defined by the…
Abstract Number: 559 • 2012 ACR/ARHP Annual Meeting
Utility of Dual-Energy X-Ray absorptiometry Scanning and Risk of Osteoporosis in Ankylosing Spondylitis; A Prospective Study
Marina N. Magrey¹ and Muhammad Asim Khan², ¹Case Western Reserve University School of Medicine at MetroHealth Medical Center, Cleveland, OH, ²Medicine/ Rheumatology, CASE at MetroHealth Med Center, Cleveland, OH
Background/Purpose: Conventional DXA imaging of spine and hip to measure bone mineral density (BMD) has limitations in patients with ankylosying spondylitis (AS) as their spinal…
Abstract Number: 560 • 2012 ACR/ARHP Annual Meeting
Proteomic Profiling of Synovial Fluid Reveals Candidate Psoriatic Arthritis Biomarkers
Daniela Cretu¹, Ihor Batruch², Punit Saraon³, Dafna D. Gladman⁴, Fawnda Pellett⁵, Eleftherios Diamandis⁶ and Vinod Chandran⁷, ¹Department of Laboratory Medicine and Pathobiology, University of Toronto, Department of Laboratory Medicine and Pathobiology, Toronto, ON, Canada, ²Department of Pathology and Lab Medicine,, Mount Sinai Hospital, Toronto, ON, Canada, ³Department of Pathology and Lab Medicine, Mount Sinai Hospital, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada, ⁴Division of Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ⁵Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁶Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada, ⁷Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada
Background/Purpose: Psoriatic arthritis (PsA) is a unique form of arthritis occurring in 30% of psoriasis patients. There is a high prevalence of undiagnosed PsA in…
Abstract Number: 561 • 2012 ACR/ARHP Annual Meeting
Performance of Magnetic Resonance Imaging in Detection of Chronic Structural Changes in Sacroiliac Joints As Compared to Conventional X-Rays in Axial Spondyloarthritis
Denis Poddubnyy¹, Inna Gaydukova², Hildrun Haibel¹, In-Ho Song¹ and Joachim Sieper¹, ¹Medical Department I, Rheumatology, Charité Medical University, Campus Benjamin Franklin, Berlin, Germany, ²Hospital Therapy, Saratov State Medical University, Saratov, Russia
Background/Purpose: Conventional x-rays of the sacroiliac joints (SIJ) remains the first imaging method in case of suspicion of axial spondyloarthritis (SpA). Moreover, a diagnosis of…
Abstract Number: 562 • 2012 ACR/ARHP Annual Meeting
Prevalence and Predictors of Significant Liver Fibrosis in Methotrexate Treated Rheumatoid and Psoriatic Arthritis Patients Using Transient Elastography (fibroscan)
WC Chan¹, ML Yip² and CK Loo¹, ¹Division of Gastroenterology and Hepatology, Department of Medicine, Kwong Wah Hospital, Kowloon, Hong Kong, ²Division of Rheumatology, Department of Medicine, Kwong Wah Hospital, Kowloon, Hong Kong
Background/Purpose: Methotrexate ( MTX ) is an anchor drug in the treatment of Rheumatoid ( RA ) and Psoriatic arthritis ( PSA )and is the…
Abstract Number: 563 • 2012 ACR/ARHP Annual Meeting
In Ankylosing Spondylitis, a Decrease in MRI Spinal Inflammation Predicts Improvement in Spinal Mobility Independently of Patient Reported Symptomatic Improvement
Pedro Machado¹, Robert Landewé², Jürgen Braun³, Xenofon Baraliakos⁴, Kay-Geert A. Hermann⁵, Benjamin Hsu⁶, Daniel Baker⁷ and Désirée van der Heijde¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam and Atrium Medical Center, Heerlen, Netherlands, ³PsAID taskforce, EULAR, Zurich, Switzerland, ⁴Rheumatology, Rheumazentrum Ruhrgebiet, Herne, Germany, ⁵Radiology, Charité Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany, ⁶Janssen Research & Development, LLC., Spring House, PA, ⁷Research and Development, Centocor Inc., Malvern/Philadelphia, PA
Background/Purpose: It has been previously shown that spinal mobility in ankylosing spondylitis (AS) is associated with the level of inflammation of the spine. However an…
Abstract Number: 564 • 2012 ACR/ARHP Annual Meeting
Almost 40% of Patients with Chronic Back Pain Starting Before the Age of 45 Fulfill the ASAS Axial Spondyloarthritis Criteria
Manouk de Hooge¹, Rosaline van den Berg¹, Floris van Gaalen¹, Monique Reijnierse², Tom Huizinga¹ and Désirée van der Heijde¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Radiology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Chronic back pain is a very prevalent complaint in the general population but only a small proportion of these patients suffer from spondyloarthritis (SpA).…
Abstract Number: 565 • 2012 ACR/ARHP Annual Meeting
Fetuin A: A New Biomarker Related with Syndesmophytes in Patients with Ankylosing Spondylitis
Tugba Tuylu¹, Dilek Solmaz², Ismail Sari², Didem L. Kozaci³, Servet Akar⁴, Necati Gunay³ and Nurullah Akkoc⁵, ¹Internal Medicine, Dokuz Eylul University School of Medicine, Izmir, Turkey, ²Rheumatology, Dokuz Eylul University School of Medicine, Izmir, Turkey, ³Biochemistry, Adnan Menderes University School of Medicine, Aydin, Turkey, ⁴Rheumatology, Dokuz Eylul University School of Medicine Department of Internal Medicine Division of Rheumatology, Izmir, Turkey, ⁵Rheumatology, Dokuz Eylul University School Of Medicine, Department Of Internal Medicine, Division Of Rheumatology, Izmir, Turkey
Background/Purpose: In recent years, there is considerable interest regarding prediction and pathogenesis of syndesmophyte formation. Thus, several studies were conducted in order to identify the…
Abstract Number: 566 • 2012 ACR/ARHP Annual Meeting
Effect of TNF Antagonists On Radiographic Progression in Psoriatic Arthritis: Systematic Review and Meta-Analysis of Randomized Controlled Trials
Radjiv Goulabchand¹, Gael Mouterde¹, Cédric Lukas², Thomas Barnetche³, Jacques Morel¹ and Bernard Combe¹, ¹Rheumatology, Montpellier 1 University, Lapeyronie Hospital, Montpellier, France, ²Immuno-Rhumatologie, Hopital Lapeyronie, Montpellier, France, ³Rheumatology, CHU Bordeaux Pellegrin, Bordeaux, France
Background/Purpose: Psoriatic arthritis (PsA) can cause important structural damages which can lead to disability. TNF antagonists have shown their clinical efficacy in PsA, but only…
Abstract Number: 567 • 2012 ACR/ARHP Annual Meeting
Prevalence of Psoriasis and Psoriatic Arthritis in a Northern Population of Spain
Jose Luis Fernandez-Sueiro¹, JA Pinto¹, S. Pertega-Diaz², Manuel Acasuso³ and Ignacio Herrero de Padura⁴, ¹Rheumatology Division, Complejo Hospitalario Universitario La Coruña, La Coruña, Spain, ²Epidemiology and Statistics, Complejo Hospitalario Universitario La Coruña, La Coruña, Spain, ³Centro de Salud San José, Centro de Salud, San José, La Coruña, Spain, ⁴Centro de Salud San Jose, Centro de Salud, San José, La Coruña, Spain
Background/Purpose: There are few data in Spain evaluating the prevalence of psoriasis in the general population, accordingly there are not data evaluating the prevalence of…
Abstract Number: 568 • 2012 ACR/ARHP Annual Meeting
14-3-3 Eta Is a Modifiable Serum Biomarker That Marks Adalimumab Response in Psoriatic Arthritis
Anthony Marotta¹, A. W van Kuijk², Walter P. Maksymowych³ and Paul Peter Tak⁴, ¹Augurex Life Sciences Corp, North Vancouver, BC, Canada, ²Clinical Immunology / Rheumatology, Academic Medical Centre/University of Amsterdam, Amsterdam, Netherlands, ³Department of Medicine, University of Alberta, Edmonton, AB, Canada, ⁴Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands
Background/Purpose: 14-3-3 eta is a synovial-derived biomarker whose serum expression is independently associated with joint damage in RA and PsA. We previously reported that 14-3-3…
Abstract Number: 569 • 2012 ACR/ARHP Annual Meeting
Ustekinumab Improves Arthritis-Related and Skin-Related Quality of Life in Patients with Active Psoriatic Arthritis: Patient Reported Outcomes From Randomized and Double Blinded Phase III Psummit I Trial
Arthur Kavanaugh¹, Iain B. McInnes², Alice B. Gottlieb³, Lluis Puig⁴, Proton Rahman⁵, Christopher T. Ritchlin⁶, Shu Li⁷, Yuhua Wang⁷, Chenglong Han⁸, Alan Mendelsohn⁹ and Mittie K. Doyle⁷, ¹UCSD School of Medicine, La Jolla, CA, ²Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom, ³Tufts Medical Center, Boston, MA, ⁴Universitat Autònoma de Barcelona, ⁵Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, ⁶Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, ⁷Janssen Research & Development, LLC, Spring House, PA, ⁸Johnson & Johnson Pharmaceutical Services, LLC., Malvern, PA, ⁹Immunology, Janssen Research & Development, LLC, Spring House, PA
Ustekinumab Improves Arthritis-related and Skin-related Quality of Life in Patients with Active Psoriatic Arthritis: Patient Reported Outcomes from Randomized and Double Blinded Phase III PSUMMIT…

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