ACR Meeting Abstracts

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  • Abstract Number: 2460 • ACR Convergence 2024

    Severe Gastrointestinal Involvement in Systemic Sclerosis: A New “Transversal” Subset of Disease to Be Prioritised for Intervention Trials

    Marco Minerba1, Riccardo Bixio2, Seda Colak3, Stefano Di Donato4, Lesley-Anne Bissell5 and Francesco Del Galdo6, 11. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, 2. NIHR Leeds Biomedical Research Centre, United Kingdom, Leeds, United Kingdom, 2University of Verona, Verona, Verona, Italy, 3Gulhane Training and Research Hospital, Ankara, Turkey, 4Leeds Institute of Rheumatic and Musculoskeletal Medicine, Chapel Allerton Hospital, Leeds, UK, Leeds, United Kingdom, 5Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 6University of Leeds, Leeds, United Kingdom

    Background/Purpose: Gastrointestinal (GI) involvement is the most frequent internal complication of systemic sclerosis (SSc) and, when severe, it has a major influence on patient function.…
  • Abstract Number: 0393 • ACR Convergence 2024

    Effectiveness of Secukinumab in TMJ Symptoms in Children with JPsA and ERA: A Secondary Data Analysis of JUNIPERA

    Marianne Kerski1, Smriti Mohan1, Cynthia Vizcaya2, Reema Sutariya3, Weibin Bao3 and Matthew Stoll4, 1University of Michigan, Ann Arbor, MI, 2Novartis Pharmaceutical Corporation, East Hanover, NJ, 3Novartis Pharmaceuticals Corporation, East Hanover, NJ, 4University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Early recognition and treatment of temporomandibular joint (TMJ) arthritis in children with juvenile idiopathic arthritis (JIA) is of high importance given its impact on…
  • Abstract Number: 0403 • ACR Convergence 2024

    Comparing Domains Reported by Patients and Other Collaborators in CNO and SAPHO: A Qualitative Study and Scoping Review Using the OMERACT Process

    Melissa Oliver1, susan Thornhill2, Beverley Shea3, Jonathan Akikusa2, Christian Hedrich4, Philip Mease5 and Yongdong (Dan) Zhao6, and OMERACT CNO & SAPHO Working Group, 1Indiana University, Indianapolis, IN, 2Royal Children's Hospital, Parkville, Victoria, Australia, 3Ottawa Hospital Research Institute, Ottawa, ON, Canada, 4University of Liverpool, Liverpool, United Kingdom, 5Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA, 6University of Washington, Redmond, WA

    Background/Purpose: Disease outcome measures for chronic nonbacterial osteomyelitis (CNO) & Synovitis, Acne, Pustulosis, Hyperostosis and Osteitis (SAPHO) have been proposed and reported but have lacked…
  • Abstract Number: 0407 • ACR Convergence 2024

    Prevalence of Autoimmune Diseases in 8244 Family Members of Children with Juvenile Idiopathic Arthritis: A Study from India

    Lekshmi Minikumari Rahulan1, Able Lawrence2 and Amita Aggarwal3, 1Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India, 2SGPGIMS, Lucknow, Lucknow, Uttar Pradesh, India, 3Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, Lucknow, Uttar Pradesh, India

    Background/Purpose: Familial aggregation of autoimmune disease as well as co-occurrence of multiple autoimmune diseases in one individual is known and it suggests a shared genetic…
  • Abstract Number: 0409 • ACR Convergence 2024

    Differences in Clinical Presentation and Outcomes Between Down Syndrome-Associated Arthritis and Juvenile Idiopathic Arthritis

    Irene Chern1, Jade Singleton2, Xing Wang3 and Jordan Jones4, 1St. Christopher's Hospital for Children, Philadelphia, PA, 2Seattle Children's Hospital, Seattle, 3Biostatistics Epidemiology and Analytics in Research, Seattle Children’s Research Institute, Seattle, WA, 4Children's Mercy Kansas City, Kansas City, MO

    Background/Purpose: Down syndrome (DS), a disorder caused by triplication of chromosome 21, affects around 1 in 1000 births making it one of the most common…
  • Abstract Number: 0408 • ACR Convergence 2024

    Analysis of Protein Biomarkers for the Prediction of IL-1 Inhibitor Treatment Response in the CARRA First-line Options for Systemic Juvenile Idiopathic Arthritis Treatment (FROST) Study

    Michael Matt1, Mariana Correia Marques2, Sabrina Fuehner3, Lexi Auld1, George Tomlinson4, Michael Ombrello5, Yukiko Kimura6, Christoph Kessel7 and grant schulert1, and the CARRA FROST Investigators, 1Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2National Institutes of Health, Bethesda, MD, 3Universitaetsklinikum Muenster, Muenster, Germany, 4University of Toronto, Toronto, ON, Canada, 5National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, 6Hackensack Meridian School of Medicine, New York, NY, 7University Hospital Muenster, Muenster, Germany

    Background/Purpose: IL-1 inhibitors are both widely used and highly effective as first-line therapy for children with systemic juvenile idiopathic arthritis (sJIA); however, the mechanisms underlying…
  • Abstract Number: 0392 • ACR Convergence 2024

    Evaluation for the Presence of Antibodies to Malondialdehyde-Acetaldehyde Adduct in Juvenile Idiopathic Arthritis and Its Subtypes

    Geoffrey Thiele1, Panteha Hayati Rezvan2, Michal Cidon2, Carlos Hunter3, Michael Duryee3, Ted Mikuls3 and Geoffrey Thiele3, 1Children's Hospital of Los Angeles, Omaha, NE, 2Children's Hospital of Los Angeles, Los Angeles, CA, 3University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Studies of rheumatoid arthritis (RA) have shown that malondialdehyde-acetaldehyde (MAA) protein adducts and anti-MAA immune responses play a pathogenic role in disease progression. Expression of…
  • Abstract Number: 0364 • ACR Convergence 2024

    Exploring 24-Hour Temporal Trends in Symptoms and Treatment of Rheumatic Disease Through Google Search Trends

    Insa Mannstadt1, J. Alex B. Gibbons2 and Bella Mehta3, 1Columbia University VP&S, New York, NY, 2Columbia University Vagelos College of Physicians & Surgeons, New York, NY, 3Hospital for Special Surgery, Weill Cornell Medicine, New York, NY

    Background/Purpose: Symptoms of rheumatic diseases such as joint stiffness and pain are known to peak in the early morning hours. In the digital age, tracking…
  • Abstract Number: 0399 • ACR Convergence 2024

    Eosinophilia and Exposure to IL-1 and IL-6 Blocking Biologic Medications in a Systemic Juvenile Idiopathic Arthritis Patient Cohort

    Rachel Dickey1, Doel Dhar2, Srushti Gangireddy3, Henry H. Ong3, Wei-Qi Wei3 and Anna Patrick3, 1Lipscomb University College of Pharmacy, Athens, TN, 2Monroe Carell Jr Children's Hospital at Vanderbilt, Nashville, TN, 3Vanderbilt University Medical Center, Nashville, TN

    Background/Purpose: Systemic juvenile idiopathic arthritis (SJIA) is a severe disease with symptoms of fevers, rash, and arthritis. High levels of the inflammatory cytokines interlukin-1 (IL-1)…
  • Abstract Number: 0421 • ACR Convergence 2024

    The Effect of Biologic Treatment for Psoriatic Arthritis and Axial Spondyloarthritis on Semen Parameters – a Longitudinal Study

    Katya Meridor1, Shimi Barda2, sara Pel3, sharon Nevo2, Julia Berman2, daphna paran4, Ori Elkayam5 and Ari Polachek6, 1Tel Aviv Medical Center, Kfar Saba, Israel, 2Tel-Aviv Medical Center, Tel-Aviv, Israel, 3Tel-Aviv Medical Center, Petah-Tikva, Israel, 4Tel-Aviv Medical Center, EVEN-YEHUDA, Israel, 5Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 6Tel-Aviv Medical Center, Tel-Aviv, Israel, Petah-Tikva, Israel

    Background/Purpose:  Psoriatic arthritis (PsA) and axial spondyloarthritis (AxSpA) are commonly diagnosed in young males in their reproductive years. However, only a few studies have investigated…
  • Abstract Number: 0420 • ACR Convergence 2024

    Factors Associated with Infant Feeding Behaviors Among Women with Systemic Rheumatic Diseases

    Sarah Lieber1, Lucy Masto1, Amaya Smole2, Ranqing Lan1, Michael Parides1, Jonah Levine1, Bessie Stamm1, Caroline Siegel1, Lisa Mandl1, Michael Lockshin3, Medha Barbhaiya1 and Lisa Sammaritano4, 1Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, Brooklyn, NY, 3Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 4Hospital for Special Surgery, Scarsdale, NY

    Background/Purpose: Although guidelines support acceptability of breastfeeding (BF)/pumping in women with systemic rheumatic diseases (SRDs) when taking BF-compatible medications, little is known about factors influencing…
  • Abstract Number: 0433 • ACR Convergence 2024

    Male Perspective on Reproductive Health in Rheumatology Patients: A Cross-sectional Study

    Eleonora Giacobbe1, Maria Chiara Gerardi2, Clizia Gagliardi2, Sara Benedetti2, Giuseppina Di Raimondo2, Assunta Ascione3, Monica Barichello2, Nicola Ughi4, Antonella Adinolfi2, Laura Belloli2, Cinzia Casu2, Maria Di Cicco2, Davide antonio Filippini2, Matteo Longhi2, Bianca Lucia Palermo2, Martina Schettino2, Giulia Segatto2, Elisa Verduci2 and Oscar Massimiliano Epis2, 1Niguarda Hospital, Milan, Milan, Lombardia, Italy, 2Niguarda Hospital, Milan, Milan, Italy, 3Niguarda Hospital, Milan, Milan, 4Niguarda Hospital, Milan, Mila, Italy

    Background/Purpose: As reproductive health is gathering attention in rheumatology and all medical fields, the male perspective on the matter is often overlooked as not directly…
  • Abstract Number: 0402 • ACR Convergence 2024

    Reporting of Clinical Features and Outcome Measures in Still’s Disease: A Systematic Literature Review of sJIA and AOSD Cohorts

    Mariana Correia Marques1, Erin Balay-Dustrude2, Claudia Bracaglia3, Marinka Twilt4, Karen Onel5, Simone Appenzeller6, Fatma Dedeoglu7, Esraa Eloseily8, Penelope Martinez Jimenez9, Rebecca Trachtman10, Francesca Minoia11 and Susan Shenoi12, and on behalf of the MAS/sJIA WP of PReS and CARRA sJIA Workgroup, 1National Institutes of Health, Bethesda, MD, 2University of Washington, Seattle, WA, 3IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy, 4Alberta Children's Hospital, University of Calgary, Cumming School of Medicine, Calgary, Alberta, Canada, Calgary, AB, Canada, 5HSS, New York, NY, 6Department of Orthopedics, Rheumatology and Traumatology. University of Campinas, Campinas, Brazil, 7Boston Children's Hospital, Boston, MA, 8Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 9Icahn School of Medicine at Mount Sinai- Elmhurst Hospital Center, Rego Park, NY, 10Icahn School of Medicine at Mount Sinai, New York, NY, 11Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy, Milan, Italy, 12Seattle Children's Hospital and Research Center, Mercer Island, WA, WA

    Background/Purpose: Multinational research is essential to globally improve the management of systemic juvenile idiopathic arthritis (sJIA), improve recognition of rare complications like lung disease, and…
  • Abstract Number: 2502 • ACR Convergence 2024

    Characterization of the Tissue Fibroblast Repertoire in IgG4-Related Ophthalmic Disease

    Eduardo Martin Nares, Gabriela Hernández-Molina, Diana Aguilar-León, Norma Ofelia Uribe-Uribe and Janette Furuzawa-Carballeda, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico

    Background/Purpose: IgG4-related disease (IgG4-RD) is a systemic fibroinflammatory condition characterized by tissue infiltration with IgG4+ plasma cells. Fibrosis in the target organs is one of…
  • Abstract Number: 2486 • ACR Convergence 2024

    Glucocorticoids May Mitigate the Risk of Avacopan-Induced Liver Dysfunction in ANCA-Associated Vasculitis: Data from a Multicenter Observational Study in Japan

    Tomohisa Uchida1, Shoichi Fukui1, Naoki Iwamoto1, Ayaka Umetsu2, Momoko Okamoto2, Keita Fujikawa2, Akinari Mizokami2, Takuya Tomokawa3, Kazusato Hara3, Yoshiro Horai3 and Atsushi Kawakami4, 1Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 2Department of Rheumatology, Japan Community Healthcare Organization (JCHO) Isahaya General Hospital, Isahaya, Japan, 3Department of Rheumatology, Sasebo City General Hospital, Sasebo, Japan, 4Nagasaki University, Nagasaki, Japan

    Background/Purpose: Avacopan, a C5a receptor inhibitor, has emerged as a novel treatment for ANCA-associated vasculitis (AAV), providing an alternative to glucocorticoids1. Despite its promising potential,…
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Embargo Policy

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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