Abstract Number: 822 • 2012 ACR/ARHP Annual Meeting
Greater Than Expected Increased Mortality Following Fragility Fractures in Women and Men with Rheumatoid Arthritis
Background/Purpose: Women and men with RA are at an increased risk for fracture [fx] as well as greater overall mortality. It is recognized that in…Abstract Number: 823 • 2012 ACR/ARHP Annual Meeting
Positive Effects of Tocilizumab On Bone Remodeling in Patients with Rheumatoid Arthritis
Background/Purpose: The anti-IL6-R antibody tocilizumab (TCZ) is an effective treatment of rheumatoid arthritis (RA). Previous studies showed that TCZ has a positive effect on bone…Abstract Number: 824 • 2012 ACR/ARHP Annual Meeting
Progressive Improvements in Cortical Mass and Thickness throughout the Hip Were Observed with Denosumab Treatment in the Freedom Trial
Background/Purpose: Denosumab (a RANK ligand antibody) reduces remodeling, increases bone mineral density, and reduces cortical porosity in postmenopausal women with osteoporosis. In FREEDOM, denosumab…Abstract Number: 825 • 2012 ACR/ARHP Annual Meeting
Osteoporosis and Vertebral Fractures Are Important Determinants of Cardiovascular Disease in Rheumatoid Arthritis
Background/Purpose: Cardiovascular disease(CVD) represents a major comorbidity and the leading cause of mortality for Rheumatoid arthritis(RA) patients. Unfortunately traditional risk factors for CVD underperform in…Abstract Number: 826 • 2012 ACR/ARHP Annual Meeting
Predictors of Return to Work During 3 Years After Start of First Tumor Necrosis Factor Antagonist in a National Cohort of Biologics-Treated Patients with Rheumatoid Arthritis
Background/Purpose: To estimate predictors of return to work during 3 years following start of anti-TNF therapy in working-age RA patients with total work disability at…Abstract Number: 827 • 2012 ACR/ARHP Annual Meeting
Sustained Development of Cardiovascular Disease in Rheumatoid Arthritis Despite Cardioprotective Treatment: The 10-Year Prospective Carre-Study
Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory joint disease which is associated with an increased cardiovascular (CV) risk. It is still unknown to what…Abstract Number: 828 • 2012 ACR/ARHP Annual Meeting
Association between Anti-Tumor Necrosis Factor Therapy and the Risk of Ischemic Stroke in Subjects with Rheumatoid Arthritis. Results From the British Society for Rheumatology Biologics Registers-Rheumatoid Arthritis (BSRBR-RA)
Background/Purpose: Subjects with rheumatoid arthritis (RA) are at increased risk of cardiovascular (CV) morbidity and mortality, with some studies suggesting an increased risk of stroke…Abstract Number: 829 • 2012 ACR/ARHP Annual Meeting
Subcutaneous Nodules Are Significantly Associated with Cardiovascular Events in Patients with Rheumatoid Arthritis: Results From a Very Large US Registry
Background/Purpose: Cardiovascular Disease (CVD) is now recognized to be a major comorbidity of patients with rheumatoid arthritis. Predictors of CVD have been shown to include…Abstract Number: 830 • 2012 ACR/ARHP Annual Meeting
Five-Year Favourable Outcome of Patients with Early Rheumatoid Arthritis in the 2000s: Data From the Espoir Cohort
Background/Purpose: To report the five-year outcome of a large national multicentre, longitudinal and prospective cohort of patients with very early arthritis and rheumatoid arthritis (RA)…Abstract Number: 831 • 2012 ACR/ARHP Annual Meeting
A Randomized, Double-Blind, Placebo-Controlled, Multiple-Dose Study to Evaluate the Safety, Tolerability, and Efficacy of Brodalumab (AMG 827) in Subjects with Rheumatoid Arthritis and an Inadequate Response to Methotrexate
Background/Purpose: A potential role for IL-17 in rheumatoid arthritis (RA) has been supported by data from clinical studies of inhibitors of the IL-17A ligand. To…Abstract Number: 832 • 2012 ACR/ARHP Annual Meeting
Peroxisome Proliferator-Activated Receptor Gamma Agonist Treatment for Rheumatoid Arthritis: A Proof-of-Concept Randomized Controlled Trial
Background/Purpose: Rheumatoid arthritis (RA), a chronic inflammatory disease, is associated with insulin resistance. Experimental evidence indicates that the relationship between insulin resistance and inflammation is…Abstract Number: 793 • 2012 ACR/ARHP Annual Meeting
Associations of Foot Forces and Pressures to Regional Foot Pain: The Framingham Foot Study
Background/Purpose: Foot pain is a risk factor for disability; however, not all foot pain is the same. Foot pain etiology can vary by region (e.g.,…Abstract Number: 794 • 2012 ACR/ARHP Annual Meeting
How Many Steps/Day Are Associated with a Community Level Gait Speed Among Older Adults with or At High Risk of Knee OA?
Background/Purpose: While recommended levels of physical activity associated with reducing the risk of poor health outcomes are well known, it is unclear what minimal level…Abstract Number: 795 • 2012 ACR/ARHP Annual Meeting
Racial Differences in Pain Coping Efficacy in Patients with Hip and Knee Osteoarthritis
Background/Purpose: Studies have shown that African Americans with osteoarthritis (OA) have greater pain than Caucasians. However, little is known about whether there are racial differences…Abstract Number: 796 • 2012 ACR/ARHP Annual Meeting
African American Adults Less Willing to Undergo Joint Replacement Surgery: The Multicenter Osteoarthritis Study
Background/Purpose: “Willingness” to undergo joint replacement surgery (JRS) is predictive of subsequent JRS among community-dwelling older adults and could, at least in part, explain the…
ACR Meeting Abstracts