ACR Meeting Abstracts

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  • Abstract Number: 994 • 2012 ACR/ARHP Annual Meeting

    The Genome-Wide Expression of Human Osteoarthritic Cartilage Shows A Differential Pattern Between Two Subgroups of OA Patients

    Ignacio Rego-Perez1, Juan Fernandez-Tajes1, Angel Soto-Hermida2, Mercedes Fernandez Moreno1, Maria Eugenia Vazquez Mosquera3, Natividad Oreiro1, Carlos Fernandez-Lopez1, Estefania Cortes Pereira1, Sara Relaño-Fernandez1 and Francisco J. Blanco1, 1INIBIC-Hospital Universitario A Coruña. Genomic Group. Rheumatology Division., A Coruña, Spain, 2INIBIC-Hospital Universitario A Coruña. Rheumatology Division. Genomic Group, A Coruña, Spain, 3Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain

     Background/Purpose: Many genes, many of them still unknown, are involved in the etiology and development of OA. Today, different tools are available to try to…
  • Abstract Number: 954 • 2012 ACR/ARHP Annual Meeting

    Diagnosis of Secondary Fibromyalgia in an Established Rheumatoid Arthritis Cohort

    Yvonne C. Lee1, Christine K. Iannaccone1, Michelle A. Frits1, M. Weinblatt2 and Nancy A. Shadick3, 1Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 2Rheumatology & Immunology, Brigham & Women's Hospital, Boston, MA, 3Rheumatology/Immunology, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: The prevalence of fibromyalgia (FM) is 7-10 times higher among rheumatoid arthritis (RA) patients than the general population.  However, the diagnosis of FM in…
  • Abstract Number: 955 • 2012 ACR/ARHP Annual Meeting

    Post – Surgical Outcome Is Correlated with Pre – Surgical Symptoms of Fibromyalgia in Patients Undergoing Spinal Surgery

    Jacob N. Ablin1, Mark Berman2, Eyal Behrbalk3, Dan Buskila4, Gilad Regev3 and Zvi Lidar3, 1Rheumatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 2Internal Medicine F, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 3Department of Neurosurgery and Orthopedic, Department of Neurosurgery and Orthopedic, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 4Ben-Gurion University, Beer-Sheva, Israel

    Background/Purpose: Chronic pain is a major symptom for which patients undergo spinal surgery. At the same time, chronic pain is considered an entity in and…
  • Abstract Number: 956 • 2012 ACR/ARHP Annual Meeting

    Learning Disability in Fibromyalgia Patients: FMS Patients Report More Language and Spatial Difficulties

    Robert S. Katz1, Alexandra Small2, Carlen Katz3 and Susan Shott1, 1Rush University Medical Center, Chicago, IL, 2University of Illinois Medical School, Chicago, IL, 3Rheumatology Associates, Chicago, IL

    Background/Purpose: Fibromyalgia patients are reported to have central sensitization and abnormal central processing of sensory input. Fibromyalgia patients also  have more neurocognitive complaints and abnormalities on…
  • Abstract Number: 957 • 2012 ACR/ARHP Annual Meeting

    Key Psychological Processes Associated with the Fibromyalgia Phenotype Exist On a Continuous Spectrum with Asymptomatic People

    Katrina Malin1 and Geoffrey O. Littlejohn2, 1Medicine, Monash University, Clayton, Australia, 2Rheumatology, Monash Medical Centre and Monash University, Clayton, VIC, Australia

    Background/Purpose: The core features of the fibromyalgia phenotype, the widespread pain and widespread tenderness, represent one extreme of a continuous spectrum with asymptomatic people at…
  • Abstract Number: 958 • 2012 ACR/ARHP Annual Meeting

    Prevelance of Spondyloarthropathy in Fibromyalgia Patients

    A.Eftal Yucel1, Derya Kaskari1 and Muhtesem Agýldere2, 1Int Medicine Rheumatology, Baskent University, Ankara, Turkey, 2Radiology, Baskent University, Ankara, Turkey

    Background/Purpose: Most of the tender points typical for fibromyalgia syndrome (FMS) are also entesis points. Besides, FMS and spondyloartropathy (SpA) can co-exist. Both disease groups…
  • Abstract Number: 960 • 2012 ACR/ARHP Annual Meeting

    Cyclobenzaprine (CBP) and Its Major Metabolite Norcyclobenzaprine (nCBP) Are Potent Antagonists of Human Serotonin Receptor 2a (5HT2a), Histamine Receptor H-1 and á-Adrenergic Receptors: Mechanistic and Safety Implications for Treating Fibromyalgia Syndrome by Improving Sleep Quality

    Bruce Daugherty, Leland Gershell and Seth Lederman, Research and Development, Tonix Pharmaceuticals, Inc., New York, NY

    Background/Purpose: Bedtime cyclobenzaprine (CBP) improves fibromyalgia symptoms (pain, fatigue, tenderness, and mood) and improves sleep quality (decreases Cyclic Alternating Pattern Type A2 + A3) (1).…
  • Abstract Number: 961 • 2012 ACR/ARHP Annual Meeting

    Cerebral Grey and White Matter Changes in Fibromyalgia Depend On Patients’ Age

    Marta Ceko1, Mary-Ann Fitzcharles2, M. Catherine Bushnell1 and Petra Schweinhardt1, 1McGill University, Montreal, QC, Canada, 2Rheumatology and Pain Management Unit, McGill University Health Centre, Montreal, QC, Canada

    Background/Purpose: Fibromyalgia (FM) patients show accelerated age-related decrease of grey matter (GM). Similarly, brain imaging studies in other chronic pain populations suggest interaction between age…
  • Abstract Number: 962 • 2012 ACR/ARHP Annual Meeting

    Pain, Sleep Disturbance, and Depression Mediate the Association Between Body Mass Index and Fatigue in Fibromyalgia

    Mary O. Whipple1, Loren L. Toussaint2, Daniel J. Clauw3, David A. Williams4, Terry H. Oh5, Jeffrey M. Thompson5, Connie A. Luedtke6 and Ann Vincent7, 1Fibromyalgia and Chronic Fatigue Clinic, Mayo Clinic, Rochester, MN, 2Psychology, Luther College, Decorah, IA, 3Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI, 4Chronic Pain & Fatigue Rsch Ctr, Univ of MI Hlth System-Lobby M, Ann Arbor, MI, 5Physical Medicine & Rehabilitation, Mayo Clinic, Rochester, MN, 6Department of Nursing, Mayo Clinic, Rochester, MN, 7General Internal Medicine, Mayo Clinic, Rochester, MN

    Background/Purpose: Previous research and clinical observation suggest that patients with chronic disease who are obese report significant fatigue. Our objective was to explore similar relationships in…
  • Abstract Number: 963 • 2012 ACR/ARHP Annual Meeting

    Efficacy of Long-Term Milnacipran Treatment in Patients Meeting Different Thresholds of Clinically Relevant Pain Relief: Subgroup Analysis of a Double-Blind, Placebo-Controlled Discontinuation Study

    Daniel J. Clauw1, Philip J. Mease2, Robert H. Palmer3, Joel M. Trugman4 and Yimin Ma4, 1Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI, 2Swedish Medical Center and University of Washington, Seattle, WA, 3Forest Research Institute, Inc., Jersey City, NJ, 4Forest Research Institute, Jersey City, NJ

    Background/Purpose: Patients with fibromyalgia (FM) who received up to 3.25 years of milnacipran (MLN) in a flexible-dose (≤200 mg/d) open-label (OL) study were eligible to…
  • Abstract Number: 964 • 2012 ACR/ARHP Annual Meeting

    High-Energy Extracorporeal Shock Wave Therapy Is Effective for Treating Chronic Calcific Tendonitis of the Shoulder: A Meta-Analysis

    Nina E. Flavin1, Raveendhara R. Bannuru1, William F. Harvey1 and Timothy E. McAlindon2, 1Rheumatology, Tufts Medical Center, Boston, MA, 2Division of Rheumatology, Tufts Medical Center, Boston, MA

    Background/Purpose: Calcific tendonitis (CT) and noncalcific tendonitis (NCT) of the shoulder is a common cause of shoulder pain and can be unresponsive to conventional therapies.…
  • Abstract Number: 965 • 2012 ACR/ARHP Annual Meeting

    Increased Number of Painful Body Sites Is Associated with Worse Pain and Disability-Associated Outcomes Among Returning Operations Enduring Freedom/Operation Iraqi Freedom Service Members

    Dennis C. Ang1, Jingwei Wu2, Samantha Outcalt3, Zhangsheng Yu4 and Matthew Bair3, 1Indiana University, Indianapolis, IN, 2Biostatistics, Indiana University School of Medicine, 3VA Center on Implementing Evidence-Based Practice, Indiana University School of Medicine, 4Department of Biostatistics, Indiana University School of Medicine

    Background/Purpose: Chronic pain is a critical health problem among Operations Enduring Freedom/Operation Iraqi Freedom service members. The deleterious impact of chronic pain on quality of…
  • Abstract Number: 966 • 2012 ACR/ARHP Annual Meeting

    A Systematic Review of Evidence for the Effectiveness of Practitioner-Based Complementary and Alternative Therapies in the Management of Fibromyalgia

    Gareth T. Jones1, Priya Paudyal2, Gary J. Macfarlane1 and the Arthritis Research UK Working Group on Complementary and3, 1Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, 2Peninsula College of Medicine and Dentistry, University of Plymouth, Plymouth, United Kingdom, 3Aberdeen

    Background/Purpose: Approximately one-quarter of the UK population uses complementary or alternative treatments (CAM) each year, and this is higher among persons with pain, or musculoskeletal…
  • Abstract Number: 967 • 2012 ACR/ARHP Annual Meeting

    Haplotypes of GTP Cyclophydrolase Gene Polymorphisms Are Protective in the Susceptibility of Fibromyalgia Syndrome

    Hwajeong Lee1, Shin-Seok Lee2, Seong-Kyu Kim3, Jung-Yoon Choe4, Seong-Ho Kim KIM5, Seong-Su Nah6, Ji Hyun Lee7, Seung-Jae Hong8, Hyun-Sook Kim9, Hye-Soon Lee10, Hyun Ah Kim11 and Chung-Il Joung12, 1Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, South Korea, 2Dept of Int Med/Rheumatology, Chonnam National University Medical School, Gwangju, South Korea, 3Catholic University of Daegu School of Medicine, Daegu, South Korea, 4Division of Rheumatology, Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, South Korea, 5Department of Internal Medicine,, Inje University Haeundae Paik Hospital, Busan, South Korea, 6Department of Internal Medicine, Soonchunhyang University, College of Medicine, Cheonan, South Korea, 7Division of Rheumatology, Department of Internal Medicine, Maryknoll Medical Center, Busan, South Korea, 8Division of Rheumatology, Department of Internal Medicine, Kyung Hee University, Seoul, South Korea, 9Internal Medicine, Chosun University Hospital, Gwangju, South Korea, 10Department of Rheumatology, Hanyang University Guri Hospital, Guri, South Korea, 11Division of Rheumatology, Department of Internal Medicine, Hallym university, Kyunggi, South Korea, 12Department of Internal Medicine, Konyang university hospital, Daejeon, South Korea

    Background/Purpose: Guanosine triphosphate cyclohydrolase 1 (GCH1) is the rate-limiting enzyme in the synthesis of tetrahydrobiopterin, which is an essential co-factor in nitric oxide (NO) production.…
  • Abstract Number: 968 • 2012 ACR/ARHP Annual Meeting

    Sympathetic Nervous System Dysfunction in Fibromyalgia and in Overlapping Central Sensitivity Syndromes. A Systematic Review of Controlled Studies

    Laura Aline Martinez1, Tania Mora1, Angelica Vargas1, Mario Fuentes1 and Manuel Martinez-Lavin2, 1Rheumatology, National Institute of Cardiology, Mexico City, Mexico, 2Chief Rheumatology, National Institute of Cardiology, Mexico City, Mexico

    Background/Purpose: Fibromyalgia often coexists and overlaps with other common painful syndromes such as chronic fatigue, irritable bowel and interstitial cystitis. Yunus proposed the label “central…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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