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  • Abstract Number: 1116 • 2013 ACR/ARHP Annual Meeting

    A Prospective Evaluation Of The Diagnostic Value Of Conventional Radiography, Ultrasound and MRI In Comparison To Clinical Examination For The Assessment Of Heel and Knee Enthesitis In Patients With Peripheral Spondyloarthritis and Controls

    Xenofon Baraliakos1, Uta Kiltz2, Frank Heldmann3, Heiner Appel4, Friedrich Dybowski5, Manfred Igelmann6, Ludwig H. Kalthoff7, Claudia Klink8, Dietmar MJ Krause9, Ertan Saracbasi3, Elmar Schmitz-Bortz10 and Jürgen Braun3, 1Rheumatology, Rheumazentrum Ruhrgebiet, Herne, Germany, 2Rheumazentrum Ruhrgebiet, Ruhr-University Bochum, Herne, Germany, 3Rheumazentrum Ruhrgebiet, Herne, Germany, 4Rheumatology and Nephrology Practice, Hamm, Germany, 5Rheumatology Practice, Herne, Germany, 6Private Rheumatology office, Bochum, Germany, 7Private rheumatology office, Herne, Germany, 8Private rheumatology office, Gladbeck, Germany, 9Internistische und rheumatologische Gemeinschaftspraxis, Gladbeck, Germany, 10Rheumatology practice, Hattingen, Germany

    Background/Purpose: Spondyloarthritides (SpA) are characterized by inflammatory and structural changes in the axial skeleton and in peripheral joints and entheses. Imaging has an essential role…
  • Abstract Number: 1117 • 2013 ACR/ARHP Annual Meeting

    Integrated 18f-Fluoride Positron Emission Tomography and Magnetic Resonance Imaging Of The Spine – a Pilot Study and Comparison Of Signals In Patients With Axial Spondyloarthritis

    Xenofon Baraliakos1, Dr. Christian Buchbender2, Ben Ostendorf3, Verena Hartung, MD4, Thorsten Poeppel, MD4 and Juergen Braun5, 1Rheumatology, Rheumazentrum Ruhrgebiet, Herne, Germany, 2Department of Diagnostic and Interventional Radiology, Univ. Duesseldorf, Düsseldorf, Germany, 3Rheumatology, Heinrich-Heine-University, Duesseldorf, GA, Germany, 4Dept. Nuclear Medicine, University Duisburg-Essen, Duisburg, Germany, 5Rheumazentrum Ruhrgebiet, Herne, Germany

    Background/Purpose:   Positron emission tomography (PET) is a high sensitive nuclear imaging technique that depicts functional processes within the body. PET scanners detect annihilation radiation from…
  • Abstract Number: 1118 • 2013 ACR/ARHP Annual Meeting

    Assessment Of Structural Damage In Patients With Ankylosing Spondylitis Using 18F-Fluoride Positron Emission Tomography-Magnetic Resonance Imaging

    GeunTae Kim1, Seung-Geun Lee2, Seong-Ho Kim3, Joung-Wook Lee4 and Seung-Hoon Baek5, 1Kosin University College of Medicine, Busan, South Korea, 2Divsion of Rheumatology, Department of Internal Medicine, Pusan National University School of Medicine, Pusan National University Hospital, Busan, South Korea, 3Internal Medicine, Division of Rheumatology, Inje University College of Medicine, Haeundae Paik Hospital, Busan, South Korea, 4Divsion of Rheumatology, Department of Internal Medicine, Busan St. Mary’s Medical Center, Busan, South Korea, 5Divsion of Rheumatology, Department of Internal Medicine, Ilsin Christian Hospital, Busan, South Korea

    Background/Purpose: 18F-fluoride uptake represents active osteoblastic bone synthesis. We explored structural damage of patients with ankylosing spondylitis (AS) using 18F-fluoride positron emission tomography (PET)-magnetic resonance…
  • Abstract Number: 1119 • 2013 ACR/ARHP Annual Meeting

    Quantification Of Inflammatory Disease Of Spine In Ankylosing Spondylitis Using Volumetric Magnetic Resonance Imaging Analysis

    Ejaz Pathan1, Adrian Lim2, Andy Graham3, Keshthra Satchithananda2, Dobrina Hull4, Sonya Abraham5, Anshul Rastogi6, Andrew Keat7, Mark Hinton8, Olga Kubassova9, Peter C. Taylor10 and J.V. Hajnal11, 1Clinical Trials Unit, Kennedy Institute of Rheumatology, London W6 8RF, United Kingdom, 2Radiology, Imperial College Healthcare NHS Trust, London, United Kingdom, 3QABC Minster House, Image Analysis, London, United Kingdom, 4Clinical Trials Unit, The Kennedy Institute of Rheumatology, London, United Kingdom, 5Rheumatology, Charing Cross Hospital, Imperial college NHS trust London UK, London W6 8RF, United Kingdom, 6Radiology, Barts and the London NHS Trust, London, United Kingdom, 7Rheumatology, Northwick Park Hospital, Harrow, United Kingdom, 8Image Analysis Ltd, London, United Kingdom, 9Image Analysis Ltd., Leeds, United Kingdom, 10NDORMS, Botnar Research Centre, University of Oxford, Oxford, United Kingdom, 11Division of Imaging Sciences, King's College London, London, United Kingdom

    Background/Purpose: To develop methodology for quantification of spinal inflammation in AS using a volumetric MRI-based technique and to explore relationships between these findings and clinical measures…
  • Abstract Number: 1120 • 2013 ACR/ARHP Annual Meeting

    Concordance Between ‘a Positive MRI Of The Sacroiliac joints’ Based On The Local Reading Versus a Centralised Reading: Experience From The DESIR-Cohort

    Rosaline van den Berg1, Fabrice Thévenin2, Antoine Feydy2, Pascal Claudepierre3, Monique Reijnierse4, Alain Saraux5 and Désirée van der Heijde1, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Radiology B, Paris Descartes University, Côchin Hospital, APHP, Paris, France, 3Rheumatology, Henri Mondor Teaching Hospital, AP-HP, Créteil, France, 4Radiology, Leiden University Medical Center, Leiden, Netherlands, 5Department of rheumatology and unit of immunology (EA 2216), Université Brest Occidentale, Brest, France

    Background/Purpose: Reading of MRIs of the sacroiliac joints (MRI-SI) in clinical trials is usually performed by ≥1 trained readers while in daily practice this is…
  • Abstract Number: 1121 • 2013 ACR/ARHP Annual Meeting

    Volatility Of The Site and Type Of Lesions In The Spine In Patients With Recent Onset Spondyloarthritis and Possible Spondyloarthritis Over a 3-Month Period

    Rosaline van den Berg1, Manouk de Hooge1, Victoria Navarro-Compán1, Monique Reijnierse2, Floris van Gaalen1, Karen Fagerli3, Robert Landewé4,5, Maikel van Oosterhout6, Roberta Ramonda7, Tom Huizinga1 and Désirée van der Heijde1, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Radiology, Leiden University Medical Center, Leiden, Netherlands, 3Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 4Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, 5Rheumatology, Atrium Medical Center, Heerlen, Netherlands, 6Rheumatology, GHZ Hospital, Gouda, Netherlands, 7Rheumatology Unit, University of Padova, Padova, Italy

    Background/Purpose: Inflammatory lesions on MRI of the sacroiliac joints show volatility over a short period of 3 months in patients with recent onset axial spondyloarthritis…
  • Abstract Number: 1122 • 2013 ACR/ARHP Annual Meeting

    How Reliable Is The Scoring Of Msasss In Clinical Practice In Centers Participating In DESIR? Comparison With The Gold Standard Central Reading

    Pascal Claudepierre1, Manouk de Hooge2, Antoine Feydy3, Monique Reijnierse4, Alain Saraux5, Maxime Dougados6 and Désirée van der Heijde7, 1Rheumatology, Henri Mondor Teaching Hospital, AP-HP, Créteil, France, 2Leiden University Medical Center, Leiden, Netherlands, 3Radiology B, Paris Descartes University, Côchin Hospital, APHP, Paris, France, 4Radiology, Leiden University Medical Center, Leiden, Netherlands, 5Rhumatologie, CHU de la Cavale Blanche, Brest Cedex, France, 6Rheumatology B Department, Paris-Descartes University, Cochin Hospital, Paris, France, 7Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Spinal X-rays are considered as gold standard for assessing structural damage in the spine in AS, and a scoring system, the modified Stoke Ankylosing…
  • Abstract Number: 1123 • 2013 ACR/ARHP Annual Meeting

    Comparison Of The Performance Of The BASRI and Msasss In Patients With Early Inflammatory Back Pain From The DESIR Cohort

    Manouk de Hooge1, Pascal Claudepierre2, Antoine Feydy3, Monique Reijnierse4, Alain Saraux5, Maxime Dougados6 and Désirée van der Heijde1, 1Leiden University Medical Center, Leiden, Netherlands, 2Rheumatology, Henri Mondor Teaching Hospital, AP-HP, Créteil, France, 3Radiology B, Paris Descartes University, Côchin Hospital, APHP, Paris, France, 4Radiology, Leiden University Medical Center, Leiden, Netherlands, 5Rhumatologie, CHU de la Cavale Blanche, Brest Cedex, France, 6Rheumatology B Department, Paris-Descartes University, Cochin Hospital, Paris, France

    Background/Purpose: For assessing structural damage in AS on spinal X-rays the Bath Ankylosing Spondylitis Radiology Index (BASRI) and modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS) scoring systems can…
  • Abstract Number: 1124 • 2013 ACR/ARHP Annual Meeting

    Lumbar Degenerative Changes In The Spondyloartritis Caught Early Cohort

    F. de Bruin1, S. ter Horst2, Karen Fagerli3, R. Landewe4, M. van Oosterhout5, J.L Bloem1, D. van der Heijde6 and M. Reijnierse1, 1Radiology, Leiden University Medical Center, Leiden, Netherlands, 2LUMC, Leiden, Netherlands, 3Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 4Division of Clinical Immunology and Rheumatology, Academic Medical Center / University of Amsterdam, Amsterdam, Netherlands, 5Groene Hartziekenhuis, Gouda, Netherlands, 6Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: The early diagnosis of axial spondyloarthritis (axSpA) is difficult, however new classification criteria are available, the ASAS axSpA criteria. The SPondyloArthritis Caught Early (SPACE)…
  • Abstract Number: 1125 • 2013 ACR/ARHP Annual Meeting

    Fatigue In Ankylosing Spondylitis Is Associated With The Brain Networks Of Sensory Salience and Attention

    Robert Inman1, Q. Wu2 and Karen Davis3, 1Immunlogy and Institute of Medical Science, University of Toronto and Toronto Western Hospital, Toronto, ON, Canada, 2Research, Toronto Western Research Institute, Toronto, ON, Canada, 3Department of Surgery, Toronto Western Research Institute, Toronto, ON, Canada

    Background/Purpose: Fatigue is one of the cardinal features of ankylosing spondylitis (AS) and contributes substantially to the disability associated with this disease. The mechanisms underlying…
  • Abstract Number: 1126 • 2013 ACR/ARHP Annual Meeting

    Opportunistic Computed Tomography Screening For Determining Osteoporosis In Patients With Ankylosing Spondylitis and Spine Fractures

    Amanda Cagan1, Osa Emohare1, Robert Morgan1, David Polly2 and Elie Gertner3, 1Spine and Spinal Cord Injury, Regions Hospital, Saint Paul, MN, 2Division of Orthopedics, University of Minnesota, Minneapolis, MN, 3Section of Rheumatology, Regions Hospital and University of Minnesota Medical School, St. Paul, MN

    Background/Purpose: In advanced disease Ankylosing Spondylitis (AS) is frequently associated with a reduction in bone mineral density (BMD) which contributes to pain and predisposes to…
  • Abstract Number: 1127 • 2013 ACR/ARHP Annual Meeting

    Semiquantitative MRI Features Of Knee Osteoarthritis Show Compartment-Specific Relationships With Quantitative Cartilage Thickness Loss: The Multicenter Osteoarthritis Study

    Ali Guermazi1, Felix Eckstein2, Daichi Hayashi3, Frank Roemer4, Wolfgang Wirth2, Tianzhong Yang5, Jingbo Niu6, Leena Sharma7, Michael C. Nevitt8, Cora E. Lewis9, James Torner10 and David T. Felson11, 1Boston University, Boston, MA, 2Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, 3Department of Radiology, Boston University School of Medicine, Boston, MA, 4Radiology, Boston University School of Medicine, Boston, MA, 5Clinical Epidemiology, Boston University School of Medicine, Boston, MA, 6Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 7Northwestern University, Chicago, IL, 8Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, 9Preventive Medicine, University of Alabama, Birmingham, Birmingham, AL, 10Epidemiology, University of Iowa, Iowa City, Iowa City, IA, 11Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA

    Background/Purpose: Structural progression of knee OA has been associated with several radiographic and MRI-measured pathological features of OA, including malalignment, meniscal pathology and bone marrow…
  • Abstract Number: 1129 • 2013 ACR/ARHP Annual Meeting

    Development and Validation Of a Rapid Knee Cartilage Quantification Method

    Ming Zhang1, Jeffrey B. Driban2, Lori Lyn Price3, Daniel Harper1, Grace H. Lo4, Eric Miller5, Robert J. Ward6 and Timothy E. McAlindon7, 1Rheumotology, Tufts Medical Center, Boston, MA, 2Rheumatology, Tufts Medical Center, Boston, MA, 3Biostatistics Research Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, 4VA HSR&D Center for Innovations in Quality, Effectiveness and Safety; Medical Care Line and Research Care Line; Department of Medicine, Michael E. DeBakey VA Medical Center, Baylor College of Medicine, Houston, TX, 5Department of Electrical and Computer Engineering, Tufts University, Medford, MA, 6Radiology, Tufts Medical Center, Boston, MA, 7Division of Rheumatology, Tufts Medical Center, Boston, MA

    Background/Purpose: Cartilage morphometry on magnetic resonance images (MRIs) may become an acceptable outcome measure for clinical trials among patients with knee osteoarthritis (OA). However, obtaining…
  • Abstract Number: 1130 • 2013 ACR/ARHP Annual Meeting

    Change In Knee Osteophyte Volume By Semi-Automated Method In Knee Osteoarthritis Over Four Years Using 3T DESS 3D MRI

    Michael Hakky1, Charles Ratzlaff2, Ali Guermazi3, Mohamed Jarraya4 and Jeffrey W. Duryea5, 1Radiology, Lahey Clinic, Burlington, MA, 2Harvard Medical School / Brigham and Women's Hospital, Boston, MA, 3Boston University, Boston, MA, 4Department of Radiology, Boston University School of Medicine, Boston, MA, 5Radiology, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: The development and growth of osteophytes are considered a radiographic surrogate for osteoarthritis (OA) at the knee. Methods to determine osteophyte burden are largely…
  • Abstract Number: 1131 • 2013 ACR/ARHP Annual Meeting

    Peri-Articular Fractal Signature Analysis and Bone Mineral Density Measure Different Aspects Of Bone: Cross-Sectional Data From The Osteoarthritis Initiative

    Jeffrey B. Driban1, Felix Liu2, Alina O'Brien3, Lori Lyn Price4, Grace H. Lo5, Michael C. Nevitt6, Charles Eaton7, Timothy E. McAlindon8 and John A. Lynch9, 1Rheumatology, Tufts Medical Center, Boston, MA, 2University of California at San Francisco, San Francisco, CA, 3Tufts Medical Center, Boston, MA, 4Biostatistics Research Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, 5VA HSR&D Center for Innovations in Quality, Effectiveness and Safety; Medical Care Line and Research Care Line; Department of Medicine, Michael E. DeBakey VA Medical Center, Baylor College of Medicine, Houston, TX, 6Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, 7Center for Primary Care and Prevention, Memorial Hospital of Rhode Island, Providence, RI, 8Division of Rheumatology, Tufts Medical Center, Boston, MA, 9Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA

    Background/Purpose: Peri-articular fractal signature analysis (FSA) and bone mineral density (paBMD) are potentially cost-effective prognostic imaging markers for osteoarthritis (OA) progression. While we know that…
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