Abstract Number: 958 • 2012 ACR/ARHP Annual Meeting
Prevelance of Spondyloarthropathy in Fibromyalgia Patients
Background/Purpose: Most of the tender points typical for fibromyalgia syndrome (FMS) are also entesis points. Besides, FMS and spondyloartropathy (SpA) can co-exist. Both disease groups…Abstract Number: 960 • 2012 ACR/ARHP Annual Meeting
Cyclobenzaprine (CBP) and Its Major Metabolite Norcyclobenzaprine (nCBP) Are Potent Antagonists of Human Serotonin Receptor 2a (5HT2a), Histamine Receptor H-1 and á-Adrenergic Receptors: Mechanistic and Safety Implications for Treating Fibromyalgia Syndrome by Improving Sleep Quality
Background/Purpose: Bedtime cyclobenzaprine (CBP) improves fibromyalgia symptoms (pain, fatigue, tenderness, and mood) and improves sleep quality (decreases Cyclic Alternating Pattern Type A2 + A3) (1).…Abstract Number: 961 • 2012 ACR/ARHP Annual Meeting
Cerebral Grey and White Matter Changes in Fibromyalgia Depend On Patients’ Age
Background/Purpose: Fibromyalgia (FM) patients show accelerated age-related decrease of grey matter (GM). Similarly, brain imaging studies in other chronic pain populations suggest interaction between age…Abstract Number: 962 • 2012 ACR/ARHP Annual Meeting
Pain, Sleep Disturbance, and Depression Mediate the Association Between Body Mass Index and Fatigue in Fibromyalgia
Background/Purpose: Previous research and clinical observation suggest that patients with chronic disease who are obese report significant fatigue. Our objective was to explore similar relationships in…Abstract Number: 963 • 2012 ACR/ARHP Annual Meeting
Efficacy of Long-Term Milnacipran Treatment in Patients Meeting Different Thresholds of Clinically Relevant Pain Relief: Subgroup Analysis of a Double-Blind, Placebo-Controlled Discontinuation Study
Background/Purpose: Patients with fibromyalgia (FM) who received up to 3.25 years of milnacipran (MLN) in a flexible-dose (≤200 mg/d) open-label (OL) study were eligible to…Abstract Number: 964 • 2012 ACR/ARHP Annual Meeting
High-Energy Extracorporeal Shock Wave Therapy Is Effective for Treating Chronic Calcific Tendonitis of the Shoulder: A Meta-Analysis
Background/Purpose: Calcific tendonitis (CT) and noncalcific tendonitis (NCT) of the shoulder is a common cause of shoulder pain and can be unresponsive to conventional therapies.…Abstract Number: 965 • 2012 ACR/ARHP Annual Meeting
Increased Number of Painful Body Sites Is Associated with Worse Pain and Disability-Associated Outcomes Among Returning Operations Enduring Freedom/Operation Iraqi Freedom Service Members
Background/Purpose: Chronic pain is a critical health problem among Operations Enduring Freedom/Operation Iraqi Freedom service members. The deleterious impact of chronic pain on quality of…Abstract Number: 966 • 2012 ACR/ARHP Annual Meeting
A Systematic Review of Evidence for the Effectiveness of Practitioner-Based Complementary and Alternative Therapies in the Management of Fibromyalgia
Background/Purpose: Approximately one-quarter of the UK population uses complementary or alternative treatments (CAM) each year, and this is higher among persons with pain, or musculoskeletal…Abstract Number: 967 • 2012 ACR/ARHP Annual Meeting
Haplotypes of GTP Cyclophydrolase Gene Polymorphisms Are Protective in the Susceptibility of Fibromyalgia Syndrome
Background/Purpose: Guanosine triphosphate cyclohydrolase 1 (GCH1) is the rate-limiting enzyme in the synthesis of tetrahydrobiopterin, which is an essential co-factor in nitric oxide (NO) production.…Abstract Number: 968 • 2012 ACR/ARHP Annual Meeting
Sympathetic Nervous System Dysfunction in Fibromyalgia and in Overlapping Central Sensitivity Syndromes. A Systematic Review of Controlled Studies
Background/Purpose: Fibromyalgia often coexists and overlaps with other common painful syndromes such as chronic fatigue, irritable bowel and interstitial cystitis. Yunus proposed the label “central…Abstract Number: 969 • 2012 ACR/ARHP Annual Meeting
Presence of Small Fiber Neuropathy in a Cohort of Patients with Fibromyalgia
Background/Purpose: The pain associated with fibromyalgia is classically described as deep, muscular, aching and flu-like; however, a significant percentage of patients with fibromyalgia also describe…Abstract Number: 970 • 2012 ACR/ARHP Annual Meeting
Genetic Interactions Between SNP Variants in C3 Receptor Subunits in Patients with SLE
Background/Purpose: Genome-wide and candidate gene studies have supported a role for genes involved in immune complex processing as being important contributors to development of SLE. …Abstract Number: 971 • 2012 ACR/ARHP Annual Meeting
Association of adam33 Polymorphisms with Systemic Lupus Erythematosus
Background/Purpose: A Disintegrin and Metalloprotease 33 (ADAM33) is a member of a family of genes that encode membrane-anchored proteins with a disintegrin and a metalloprotease…Abstract Number: 972 • 2012 ACR/ARHP Annual Meeting
Associations of Genetic Polymorphisms of Microrna-146a and Its Target Interleukin-1-Receptor-Associated Kinase 1 with Ankylosing Spondylitis
Background/Purpose: Tumor necrosis factor-α (TNF-α) and interleukin-1 (IL-1) were important mediators of inflammation response in the development of ankylosing spondylitis (AS). Especially, microRNA (miR)-146a targets…Abstract Number: 973 • 2012 ACR/ARHP Annual Meeting
New Genetic Risk Loci for the Radiographic Severity of Rheumatoid Arthritis
Background/Purpose: The severity of joint destruction is highly variable between Rheumatoid Arthritis (RA) patients; approximately 54% of this variance is explained by genetic factors. Many…