ACR Meeting Abstracts

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  • Abstract Number: 1175 • 2012 ACR/ARHP Annual Meeting

    Decreased Frequency of Th17 Cells in Early Rheumatoid Arthritis

    Irene Arroyo-Villa1, M. Belén Bautista-Caro1, Alejandro Balsa2, Pilar Aguado2, Laura Nuño2, Gema Bonilla3, Amaya Puig-Kröger4, Emilio Martín-Mola2 and M. Eugenia Miranda-Carús2, 1Rheumatology, Hospital La Paz - IdiPaz, Madrid, Spain, 2Hospital La Paz-IdiPaz, Madrid, Spain, 3Rheumatology, Hospital La Paz, Madrid, Spain, 4Immuno-oncology, Hospital Gregorio Marañon, Madrid, Spain

    Background/Purpose: Our objective was to examine the frequency and phenotype of Th17 cells in the peripheral blood of early RA (eRA) patients. Methods: CD4+ T…
  • Abstract Number: 1136 • 2012 ACR/ARHP Annual Meeting

    Aesthetic Dissatisfaction in Hand Osteoarthritis Patients, Its Impact and Risk Factors

    R. Liu, L.J.J. Beaart-van de Voorde, T.W.J. Huizinga and M. Kloppenburg, Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Hand osteoarthritis (HOA) leads to aesthetic damage and is rarely studied. We aim to investigate in HOA patients the prevalence of dissatisfaction with the…
  • Abstract Number: 1137 • 2012 ACR/ARHP Annual Meeting

    Clinimetric Properties of a New Outcome Measure:the Hand-Osteoarthritis Aesthetic Damage Index

    N. Bellamy and Joan Hendrikz, Conrod, The University of Queensland, Herston, Queensland, Australia

    Background/Purpose: The 2006 OARSI Guidelines for hand OA clinical trials, recognised the potential value of an aesthetic damage assessment, but acknowledged the absence of any…
  • Abstract Number: 1138 • 2012 ACR/ARHP Annual Meeting

    Nonpharmacologic and Pharmacologic Therapy Utilization by Primary Care Providers for Hand Osteoarthritis-Comparative Review by Electronic Health Record Data Mining and in-Home Visit Verification

    Gale A. McCarty, President, Rheum.Ed Consulting, Harborside, ME

    Background/Purpose: To compare current utilization of usual nonpharmacologic (NP) and pharmacologic (P) therapies for hand osteoarthritis (OA) by primary care providers (PCPs) and patients (Pts)…
  • Abstract Number: 1139 • 2012 ACR/ARHP Annual Meeting

    Inhaled Nitrous Oxide Facilitates Access to Intra-Articular Corticosteroid Injections in Children with Juvenile Idiopathic Arthritis

    Mercedes O. Chan1, Ruth Wyllie2 and H. E. Foster3, 1Department of Pediatrics, Division of Pediatric Rheumatology, University of British Columbia and British Columbia's Children's Hospital, Vancouver, BC, Canada, 2Paediatric Rheumatology, Newcastle Hospitals, NHS Foundation Trust, Newcastle Upon Tyne, United Kingdom, 3Paediatric Rheumatology, Newcastle Hospitals NHS Foundation Trust, Great North Children's Hospital, Newcastle Upon Tyne, United Kingdom

    Background/Purpose: Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease of childhood affecting 1 in 1000 children. Medical management for arthritis often includes intra-articular…
  • Abstract Number: 1140 • 2012 ACR/ARHP Annual Meeting

    Response to Adalimumab in 40 Patients with refractory juvenile Idiopathic Arthritis-Associated Uveitis. A Multicenter Study

    Vanesa Calvo-Río1, Ricardo Blanco2, Manuel Díaz-Llopis3, David Salom4, Carmen García-Vicuña5, Miguel Cordero-Coma6, Norberto Ortego7, Marta Suarez-de-Figueroa8, J. Carlos Fernandez-Cid9, A. Fonollosa Calduch10, Ángel M. García-Aparicio11, Jose M. Benítez-del-Castillo12, Jose L. Olea13, Javier Loricera14 and Miguel Angel González-Gay15, 1Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain, 2Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain, 3Hospital Universitario La Fe de Valencia, Valencia, 4Department of Ophthalmology, Hospital Universitario La Fe de Valencia, Valencia, Spain, 5Hospital Sant Joan de Déu, Barcelona, Barcelona, 6Departament of Ophthalmology, Hospital de León, León, Spain, 7Hospital San Cecilio. Granada, Granada, Spain, 8Department of Ophthalmology, Hospital Ramon y Cajal, Madrid, Spain, 9Departament of Ophthalmology, Hospital de Pontevedra, Pontevedra, Spain, 10Ophthalmology, Hospital de Cruces, Barakaldo, Spain, 11Hospital Virgen Salud, Toledo, Toledo, 12Departament of Ophthalmology, Hospital Clínico San Carlos, Madrid, 13Departament of Ophthalmology, Hospital Son Dureta, Palma de Mallorca, Spain, 14Rheumatology, Hospital Universitario Marqués de Valdecilla. IFIMAV. Santander. Spain, Santander, Spain, 15Rheumatology, Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain

    Background/Purpose: To assess the efficacy and safety of treatment with adalimumab therapy in patients with refractory Juvenile Idiopathic Arthritis (JIA)-associated uveitis. Methods: Multicenter study on…
  • Abstract Number: 1141 • 2012 ACR/ARHP Annual Meeting

    Safety of Celecoxib and Non-Selective Non-Steroidal Anti-Inflammatory Drugs in Juvenile Idiopathic Arthritis

    Rachel E. Sobel1, D. J. Lovell2, Hermine Brunner3, Jennifer E. Weiss4, Paula W. Morris5, Beth S. Gottlieb6, Elizabeth C. Chalom7, Lawrence K. Jung8, Karen Onel9, Lisa Petinoit10, Donald P. Goldsmith11, Staci Abramsky-Risman12, James P., Young13 and Edward H. Giannini14, 1Epidemiology, Worldwide Safety Strategy, Pfizer, Inc., New York, NY, 2Cincinnati Children's Hospital, Cincinnati, OH, 3Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4Pediatric Rheumatology, Hackensack Univ Med Ctr, Hackensack, NJ, 5Pediatrics, Univ of Arkansas for Med Sci, Little Rock, AR, 6Pediatric Rheumatology, Cohen Children's Medical Center of New York, New Hyde Park, NY, 7Pediatrics, St. Barnabas Medical Center, Livingston, NJ, 8Pediatric Rheumatology, Children's National Medical Center, Washington, DC, 9Pediatric Rheumatology, University of Chicago Hospitals, Chicago, IL, 10Pediatric Rheumatology, 'Specially for Children, Dell Children's Medical Center, Austin, TX, 11Pediatric Rheumaology, St Christopher's Hospital for Children/ Drexel College of Medicine, Philadelphia, PA, 12Pfizer Inc, New York, NY, 13United BioSource Corporation, Ann Arbor, MI, 14Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Background/Purpose: Celecoxib, a selective COX-2 inhibitor, was approved by the FDA for the treatment of the signs and symptoms of JIA in children aged 2-17…
  • Abstract Number: 1142 • 2012 ACR/ARHP Annual Meeting

    Efficacy of Biologic Agents in Juvenile Idiopathic Arthritis: A Systematic Review Using Indirect Comparisons

    Janneke Anink1, Marieke H. Otten1, Sandra Spronk2 and Lisette W.A. Van Suijlekom-Smit1, 1Pediatric Rheumatology, Erasmus MC Sophia Children's Hospital, Rotterdam, Netherlands, 2Department of Epidemiology and Radiology, Erasmus MC, Rotterdam, Netherlands

    Background/Purpose: During the last decade the availability of biologic agents for the treatment of juvenile idiopathic arthritis (JIA) increased substantially. Because direct head-to-head trials comparing…
  • Abstract Number: 1143 • 2012 ACR/ARHP Annual Meeting

    Tocilizumab Therapy in Children with Systemic Onset Juvenile Idiopathic Arthritis. Russian Experience

    Ekaterina Alekseeva, Rina Denisova, Saniya Valieva, Tatyana Bzarova, Kseniya Isayeva, Alexandra Chomakhidze, Evgeniya Chistyakova, Tatyana Sleptsova and Elena Mitenko, Rheumatology, Scientific Center of Children's Health, Moscow, Russia

    Background/Purpose: Systemic Juvenile Idiopathic Arthritis (sJIA) is classified as an acquired autoinflammatory disease. The interleukin-1 and interleukin-6 play a pivotal role in pathogenesis of this…
  • Abstract Number: 1144 • 2012 ACR/ARHP Annual Meeting

    Phenotypic Characterization of Childhood Onset Rheumatoid Arthritis

    Emily G. Ferrell1, Lori Ponder2, Lauren Minor3, Sheila T. Angeles-Han4, Christine W. Kennedy5, Kelly A. Rouster-Stevens6, Mina Pichavant7, Larry B. Vogler8 and Sampath Prahalad9, 1Emory University School of Medicine, Atlanta, GA, 2Children's Healthcare of Atlanta, Atlanta, GA, 3Department of Pediatrics, Emory University, Atlanta, GA, 4Pediatrics, Emory University, Atlanta, GA, 5Rheumatology Immunology, Emory Children's Center, Atlanta, GA, 6Pediatric Rheumatology, Emory Univ School of Medicine, Atlanta, GA, 7Pediatrics, Emory University School of Medicine, Atlanta, GA, 8Dept of Pediatrics, Emory Univ School of Medicine, Atlanta, GA, 9Pediatrics, Emory Children's Center, Atlanta, GA

    Background/Purpose: Rheumatoid Factor positive polyarthritis (RF+ poly) is the JIA subtype that resembles adult seropositive RA. However, the ILAR classification criteria for RF+ polyarthritis do…
  • Abstract Number: 1145 • 2012 ACR/ARHP Annual Meeting

    Use of Non-Etanercept Biologics in Children with Juvenile Idiopathic Arthritis: Results From the Biologics for Children with Rheumatic Diseases Study

    Lianne Kearsley-Fleet1, Eileen Baildam2, Michael Beresford3, Rebecca Davies4, Helen E. Foster5, Katy Mowbray1, Taunton R. Southwood6, Wendy Thomson1 and Kimme L. Hyrich7, 1Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, Manchester, United Kingdom, 2Paediatric Rheumatology, Alder Hey Children's Foundation NHS Trust, Liverpool, United Kingdom, 3University of Liverpool, Institute of Translational Medicine (Child Health), Alder Hey Children's Foundation NHS Trust, Liverpool, United Kingdom, 4Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, United Kingdom, 5Institute Cellular Medicine, Musculoskeletal Research Group, Newcastle upon Tyne, United Kingdom, 6Institute of Child Health, University of Birmingham and Birmingham Children's Hospital, Birmingham, United Kingdom, 7Centre for Musculoskeletal Research, University of Manchester, Manchester, United Kingdom

    Background/Purpose: The management of juvenile idiopathic arthritis (JIA) has been revolutionised by the introduction of biologic therapy, although the majority remain unlicensed for children. Until…
  • Abstract Number: 1146 • 2012 ACR/ARHP Annual Meeting

    Choice of Systemic JIA Treatment Among Childhood Arthritis and Rheumatology Research Alliance (CARRA) Rheumatologists

    Jennifer E. Weiss1, Esi M. Morgan DeWitt2, Timothy Beukelman3, Laura E. Schanberg4, Rayfel Schneider5 and Yukiko Kimura6, 1Pediatric Rheumatology, Hackensack University Medical Center, Hackensack, NJ, 2Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 3Pediatric Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 4Pediatrics, Duke University Medical Center, Durham, NC, 5Pediatric Rheumatology Collaborative Study Group (PRCSG), Cincinnati, OH, Canada, 6Pediatric Rheumatology, Joseph M. Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack, NJ

    Background/Purpose: Despite recent advances in identifying effective treatments for systemic Juvenile Idiopathic Arthritis (sJIA), many pediatric rheumatologists continue to use corticosteroids and methotrexate. The Childhood…
  • Abstract Number: 1147 • 2012 ACR/ARHP Annual Meeting

    Definition of Improvement Thresholds in Juvenile Idiopathic Arthritis Using the JADAS

    Gerd Horneff1 and Ingrid Kaul2, 1Department of Pediatrics, Centre of Pediatric Rheumatology, Sankt Augustin, Germany, 2Institute of Medical Statistics, Informatics and Epidemiology, University of Cologne, Cologne, Germany

    Definition of improvement thresholds in juvenile idiopathic arthritis (JIA) using the JADAS  Background/Purpose: Evaluation of disease activity in JIA is fundamental in clinical assessment. The…
  • Abstract Number: 1148 • 2012 ACR/ARHP Annual Meeting

    Adalimumab – Effective Control under Refractory JIA Associated Uveitis

    Ekaterina Alekseeva1, Elena Mitenko2, Tatyana Bzarova2, Saniya Valieva2, Kseniya Isayeva2, Alexandra Chomakhidze2, Evgeniya Chistyakova2, Tatyana Sleptsova2 and Rina Denisova2, 1PRINTO, Genoa, Italy, 2Rheumatology, Scientific Center of Children's Health, Moscow, Russia

    Background/Purpose: Treatment of juvenile idiopathic arthritis (JIA)–associated uveitis  is one of the serious problems of paediatric rheumatology. JIA associated uveitis often is refractory to MTX,…
  • Abstract Number: 1149 • 2012 ACR/ARHP Annual Meeting

    Long-Term Safety of Etanercept in Patients with Juvenile Idiopathic Arthritis (JIA)

    Kirsten Minden1, Martina Niewerth2, Jens Klotsche3, Michael Hammer4, Johannes Peter Haas5, Gerd Ganser6 and Gerd Horneff7, 1Programme Area Epidemiology, German Rheumatism Research Center, a Leibniz Institute, Berlin, Germany, 2Epidemiology, German Rheumatism Research Centre, Berlin, Germany, 3Programme Area Epidemiology, German Rheumatism Research Center, a Leibniz institute, Berlin, Germany, 4Klinik fuer Rheumatologie, St. Josef-Stift, Sendenhorst, Germany, 5German Center for Pediatric and Adolescent Rheumatology, Garmisch-Partenkirchen, Germany, 6Pediatric Rheumatology, Sankt Josef Stift, Sendenhorst, Germany, 7Department of Pediatrics, Centre of Pediatric Rheumatology, Sankt Augustin, Germany

    Background/Purpose: Etanercept (Eta) has been the most frequently used biologic drug in patients with JIA. In Germany, about one in three patients with polyarticular JIA…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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