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  • Abstract Number: 1536 • 2013 ACR/ARHP Annual Meeting

    Do Patients With Ankylosing Spondylitis Have An Excess Prevalence Of Chronic Widespread PAIN?: Results From The Scotland and Ireland Registry For Ankylosing Spondylitis (SIRAS) and The Musician Study

    Fabiola Azeni1,2, Marcus Beasley1, Linda E. Dean1, Gareth T Jones3, Jane Gibson4, Piercarlo Sarzi-Puttini5 and Gary J. Macfarlane on behalf of SIRAS and MUSICIAN study investigators1, 1Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, 2Rheumatology Unit, L.Sacco University Hospital, Milan, Italy, 3Musculoskeletal Research Collaboration (Epidemiology Group),, University of Aberdeen, Aberdeen, United Kingdom, 4NHS Fife, Fife Rheumatic Diseases Unit, Kircaldy, United Kingdom, 5Rheumatology Unit, L. Sacco University Hospital, Milan, Italy

    Background/Purpose: To determine whether there is an excess prevalence of chronic widespread body pain  (CWP) in patients with Ankylosing spondylitis (AS). Methods:   Patients were…
  • Abstract Number: 1537 • 2013 ACR/ARHP Annual Meeting

    Primary & Subsequent Orthopedic Surgeries More Common In Juvenile Vs. Adult-Onset Ankylosing Spondylitis

    Deepak R. Jadon1, Ramani Arumugam1, Gavin Shaddick2, Alison L Nightingale3, Athimalaipet V Ramanan4 and Raj Sengupta1, 1Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 2Department of Mathematics, University of Bath, Bath, United Kingdom, 3Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom, 4Paediatric Rheumatology, University of Bristol Hospital Trust, Bristol, United Kingdom

    Background/Purpose: Patients experiencing ankylosing spondylitis (AS) symptoms ²16 years-of-age are classified as juvenile-onset AS (JoAS), whilst those ³17 years adult-onset AS (AoAS). We compared JoAS…
  • Abstract Number: 1538 • 2013 ACR/ARHP Annual Meeting

    The Age At Onset Of Symptoms Influence The Clinical Expression Of The Disease In Patients With Ankylosing Spondylitis

    Natalia Zamora1, Emilce Edith Schneeberger1, Luis Alejandro Cayetti2, Fernando Sommerfleck1 and Gustavo Citera1, 1Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 2Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina

    Background/Purpose: The onset of symptoms before 10 years and after 40 years is uncommon in patients with ankylosing spondylitis (AS). Some authors have found specific…
  • Abstract Number: 1539 • 2013 ACR/ARHP Annual Meeting

    Inflammation In The Posterior Elements Of The Spine Is Infrequent In Patients With Recent Onset Axial Spondyloarthritis, Especially If No Inflammation In The Vertebral Bodies Is Observed

    Rosaline van den Berg1, Manouk de Hooge1, Monique Reijnierse2, Victoria Navarro-Compán1, Karen Fagerli3, Maureen Turina4, Maikel van Oosterhout5, Roberta Ramonda6, Floris van Gaalen1, Tom Huizinga1 and Désirée van der Heijde1, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Radiology, Leiden University Medical Center, Leiden, Netherlands, 3Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 4Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, 5Rheumatology, GHZ Hospital, Gouda, Netherlands, 6Rheumatology Unit, University of Padova, Padova, Italy

    Background/Purpose: There is evidence that in almost all patients with longstanding and active ankylosing spondylitis (AS) inflammatory lesions in the posterior elements are as frequent…
  • Abstract Number: 1540 • 2013 ACR/ARHP Annual Meeting

    Sustained Clinical Remission In Patients With Non-Radiographic Axial Spondyloarthritis After Two Years Of Adalimumab Treatment

    Joachim Sieper1, Dominique L. Baeten2, Filip Van den Bosch3, Suchitrita S. Rathmann4, Jaclyn K. Anderson4 and Aileen L. Pangan4, 1Medical Department I, Rheumatology, Charité Universitätsmedizin Berlin, Campus Benjamin-Franklin, Berlin, Germany, 2Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, 3Ghent University Hospital, Ghent, Belgium, 4AbbVie Inc., North Chicago, IL

    Background/Purpose: Adalimumab (ADA) is currently approved in the EU for the treatment of severe non-radiographic axial spondyloarthritis (nr-axSpA), in patients (pts) with an elevated CRP…
  • Abstract Number: 1500 • 2013 ACR/ARHP Annual Meeting

    Use Of B Lymphocyte Stimulator Inhibitor Belimumab May Be Associated With a Decrease In the Serum Concentration Of Endothelial Growth Factor In Patients With Primary Sjögren’s Syndrome

    Slavica Bobic1, Sabeeda Kadavath2, Linda Gerber3, Ekaterini Zapantis4 and Petros V. Efthimiou5, 1Medicine, Lincoln Medical and Mental Health Center, New York, NY, 2Rheumatology, Lincoln Medical and Mental Health Center, New York, NY, 3Weill Cornell Medical College, New York, NY, 4Lincoln Medical and Mental Health Center, New York, NY, 5Medicine/Rheumatology, LM&MHC/Weill Cornell MC, New York, NY

    Background/Purpose: , Primary Sjögren's Syndrome (pSjS) is a systemic autoimmune inflammatory disease that primarily affects the lacrimal and salivary glands and is associated with B…
  • Abstract Number: 1501 • 2013 ACR/ARHP Annual Meeting

    Umbilical Cord Mesenchymal Stem Cells Inhibit The Generation Of T Follicular Helper Cell In Sjogren’s Syndrome

    Rui Liu1, Min Zhou1, Dinglei Su1, Xia Li1 and Lingyun Sun2, 1Department of Rheumatology and Immunology, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China, 2Department of Rheumatology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China

    Background/Purpose: The immune suppressive properties of mesenchymal stem cells (MSC) have garnered increasing attention over past decades. Human umbilical cord-derived MSC (UC-MSC) share similar immunosuppressive…
  • Abstract Number: 1502 • 2013 ACR/ARHP Annual Meeting

    Antibodies To Anti-Type -3 Muscarinic Acetylcholine Receptor Are Highly Prevalent To Rabbits Immunized With 4-Hydroxy-2-Noneal-Modified and 60-Kda Ro

    Valerie Harris1, Biji T. Kurien2, R. Hal Scofield3, Timothy Gross4 and Mary Girton5, 1Pathology, University of Oklahoma Health Science Center, Oklahoma City, OK, 2College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 3Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 4Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, 5Oklahoma Medical Research Foundation, Oklahoma City, OK

    Background/Purpose: In Sjörgen’s Syndrome, an autoimmune disease, the lacrimal and salivary glands are the primarily affected glands. Previous studies have proposed autoantibodies that target type-3…
  • Abstract Number: 1503 • 2013 ACR/ARHP Annual Meeting

    The Suppressive Ability Of Altered Peptide Ligands To M3R Reactive T Cells In M3R Induced Autoimmune Sialadenitis

    Hiromitsu Asashima1, Hiroto Tsuboi1, Naomi Matsuo1, Chihiro Hagiya1, Tomoya Hirota1, Mana Iizuka1, Yuya Kondo1, Isao Matsumoto2 and Takayuki Sumida1, 1Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan, 2Department of Internal Medicine, Faculty of Medicine,, University of Tsukuba, Tsukuba, Japan

    Background/Purpose: Previous studies have shown that Rag1-/- mice transferred with splenocytes of M3 muscarinic acetylcoline receptor (M3R)-/- mice immunized with M3R peptides mixture (three N-terminal…
  • Abstract Number: 1504 • 2013 ACR/ARHP Annual Meeting

    Anti-Inflammation Effect Of Peroxisome Proliferator-Activated Receptor-ã (PPAR-ã) In Non-Obese Diabetic Mice With Sjogren’s Syndrome

    Bei Xu1 and Xiaomei Li2, 1Department of Rheumatology and Immunology, The third Affiliated Hospital of Anhui Medical University, The First Hospital of Hefei, Hefei, China, 2Department of Rheumatology and Immunology, Anhui Medical University Affiliated Provincial Hospital, Hefei, Anhui, China

    Background/Purpose: To investigate the anti-inflammation effect of peroxisome proliferator-activated receptor-γ (PPAR-γ) in non-obese diabetic mice (NOD mice) with sjogren`s syndrome.Methods: Twenty 8-weeks-old female NOD mice were randomly divided into…
  • Abstract Number: 1505 • 2013 ACR/ARHP Annual Meeting

    Evaluation Of a Case Ascertainment Tool For Ankylosing Spondylitis and Axial Spondylarthritis Among All Referrals To General Rheumatology Clinics

    Eswar Krishnan1, Michael H. Weisman2, Atul A. Deodhar3, Linjun Chen1 and Lianne S. Gensler4, 1Medicine, Stanford University, Palo Alto, CA, 2Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, 3Div of Arthritis & Rheum OP-09, Oregon Health & Science University, Portland, OR, 4Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA

    Background/Purpose: Several strategies for distinguishing Ankylosing Spondylitis (AS) and Axial Spondylarthritis (axSpA) from other conditions have been proposed but have only been studied in the…
  • Abstract Number: 1506 • 2013 ACR/ARHP Annual Meeting

    Total Hip Replacement Outcomes in Ankylosing Spondylitis

    Susan M. Goodman1, Rebecca Zhu2, Wei-Ti Huang3, Mark P. Figgie4, Michael Alexiades5 and Lisa A. Mandl1, 1Rheumatology, Hospital for Special Surgery, New York, NY, 2Clinical Research, Hospital for Special Surgery, New York, NY, 3Epidemiology and Statistics, Hospital for Special Surgery, New York, NY, 4Orthopedics, Hospital for Special Surgery, New York, NY, 5Orthopaedics, Hospital for Special Surgery, New York, NY

    Background/Purpose: Historically, outcomes for total hip replacement (THR) in ankylosing spondylitis (AS) patients were poor, but contemporary outcomes are not well described. We analyzed two-year…
  • Abstract Number: 1507 • 2013 ACR/ARHP Annual Meeting

    Infection Risk in Ankylosing Spondylitis: Results From a Longitudinal Observational Cohort

    Dinny Wallis1, Arane Thavaneswaran2, Nigil Haroon1, Renise Ayearst2 and Robert D. Inman3, 1Rheumatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, 2Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 3Toronto Western Hospital, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Long term data on infection risk in ankylosing spondylitis (AS) are sparse and derived mainly from RCTs.  Anti-TNF therapy is increasingly used in AS,…
  • Abstract Number: 1508 • 2013 ACR/ARHP Annual Meeting

    How Well Are The Assessment Of Spondyloarthritis International Society (ASAS) / Outcome Measures In Rheumatology (OMERACT) Core Outcome Sets For Ankylosing Spondylitis Implemented In Randomized Clinical Trials? A Systematic Literature Review

    Wilson Bautista-Molano1,2, Victoria Navarro-Compán1, Robert Landewé3 and Désirée van der Heijde4, 1Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Department of Rheumatology, Universidad Militar Nueva Granada, Bogotá, Colombia, 3Rheumatology, Academic Medical Center, Amsterdam, Netherlands, 4Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: The Assessment of SpondyloArthritis international Society (ASAS) has selected a core set of variables to include as standardized endpoints in clinical trials and clinical…
  • Abstract Number: 1509 • 2013 ACR/ARHP Annual Meeting

    Immunogenicity, Adalimumab Levels and Clinical Response In Ankylosing Spondylitis Patients During 24 Weeks Of Follow-Up

    Eva L. Kneepkens1, James C. Wei2, Michael T. Nurmohamed3,4, Kai-Jieh Yeo5, CY Chen6, Irene E. van der Horst-Bruinsma1,7, Desiree van der Kleij8, Theo Rispens9, Gertjan Wolbink3,9 and Charlotte L. M. Krieckaert3, 1Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, 2Allergy/Immunology/Rheumatolog, Chung Shan Med Univ Hospital, Taichung, Taiwan, 3Rheumatology, Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, 4Rheumatology, VU University medical centre, Amsterdam, Netherlands, 5Division of Allergy, Immunology and Rheumatology, Chung Shan Med Univ Hospital, Taichung, Taiwan, 6Chung Shan Med Univ Hospital, Taichung, Taiwan, 7Department of Rheumatology, VU University Medical Center, Amsterdam, Netherlands, 8Sanquin Diagnostic Services, Amsterdam, Netherlands, 9Sanquin Research, Amsterdam, Netherlands

    Background/Purpose: Immunogenicity influences adalimumab levels and therefore clinical response in patients with rheumatic diseases. Objectives: To study the relation between clinical response, adalimumab levels and…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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