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  • Abstract Number: 1390 • 2012 ACR/ARHP Annual Meeting

    Vitamin D Deficiency Is Not Associated with Nor Does It Predict Progression of Coronary Artery Calcium or Carotid Intima-Media Thickness in Systemic Lupus Erythematosus

    Adnan Kiani1, Hong Fang1, Ehtisham Akhter2, Laurence S. Magder3 and Michelle Petri1, 1Johns Hopkins University School of Medicine, Baltimore, MD, 2Div of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 3Department of Epidemiology and Public Health, University of Maryland, Baltimore, MD

    Background/Purpose: :  In the general population, vitamin D deficiency is associated with cardiovascular disease including myocardial infarction and stroke.  In SLE, Vitamin D deficiency has…
  • Abstract Number: 1391 • 2012 ACR/ARHP Annual Meeting

    Anti-Ku Autoantibodies in Systemic Lupus Erythematosus Versus Autoimmune Myositis As Measured by a Novel Chemiluminescence Assay

    Michael Mahler1, Jason Wu2, Magdalena Szmyrka-Kaczmarek3, Andreas Swart4, Marvin J. Fritzler5, Jean-Luc Senécal6 and John G. Hanly7, 1Research, INOVA Diagnostics, San Diego, CA, 2Research, INOVA Diagnostics, San Diego, 3Rheumatology, Wroclaw Medical University, Wroclaw, Poland, 4Rheumatology clinic Neuss, Neuss, Germany, 5Medicine, University of Calgary, Calgary, AB, Canada, 6Rheumatology, Hôpital Notre-Dame du CHUM, Montréal, QC, Canada, 7Division of Rheumatology, Dalhousie University and Capital Health, Halifax, NS, Canada

    Background/Purpose: Autoantibodies targeting Ku, an abundant nuclear protein with DNA helicase activity, have been reported in patients with systemic autoimmune rheumatic diseases. Little is known…
  • Abstract Number: 1392 • 2012 ACR/ARHP Annual Meeting

    Clinical Correlation with Anti Double Stranded Deoxyribonucleic Acid Via Enzyme Linked Immunoassay Versus Multiplex Immunoassay

    Megan L. Krause1, Melissa R. Snyder2, Cynthia S. Crowson3, Abigail B. Green3 and Kevin G. Moder4, 1Internal Medicine, Mayo Clinic, Rochester, MN, 22Division of Clinical Biochemistry and Immunology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 3Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 4Rheumatology, Mayo Clinic, Rochester, MN

    Background/Purpose: In systemic lupus erythematosus (SLE), antibodies to double-stranded DNA (dsDNA) are utilized for disease classification and assessment of activity. Enzyme immunoassays (EIAs) and multiplex…
  • Abstract Number: 1393 • 2012 ACR/ARHP Annual Meeting

    Predictors of Panniculitis in Systemic Lupus Erythematosus

    Ashika Odhav1, Michelle Petri2 and Hong Fang2, 1University of Missouri Kansas City School of Medicine, Kansas, MO, 2Johns Hopkins University School of Medicine, Baltimore, MD

    Background/Purpose: Panniculitis is a rare, but devastating manifestation of SLE.  We examined associates of panniculitis in a large SLE cohort.  Methods: 52 out of 2,149…
  • Abstract Number: 1394 • 2012 ACR/ARHP Annual Meeting

    Health Status Burden and Impact of Fatigue On Patient Functioning in SLE Patients From a Phase 1b Study

    Michelle Petri1, Ariane K. Kawata2, Ancilla W. Fernandes3, Kavita Gajria4, Warren Greth5 and Asha Hareendran6, 1Johns Hopkins University School of Medicine, Baltimore, MD, 2United Biosource Corporation, Bethesda, MD, 3MedImmune, LLC, Gaithersburg, MD, 4MedImmune LLC, Gaithersburg, MD, 5Clinical Development, MedImmune, LLC, Gaithersburg, MD, 6United Biosource Corporation, London, MD, United Kingdom

     Background/Purpose: Systemic Lupus Erythematosus (SLE) has a significant impact on patient's quality of life. Fatigue is the most common symptom of SLE and affects between…
  • Abstract Number: 1395 • 2012 ACR/ARHP Annual Meeting

    The Validation of a New Simple Disease Activity Tool in Systemic Lupus Erythematosus (SLE): The Lupus Activity Scoring Tool (LAST) As Compared to the Sledai Selena Modification

    Majed M. Khraishi1, Rana Aslanov2 and Krista Fudge3, 1Nexus Clinical Research, Memorial University of Newfoundland, St Johns, NF, Canada, 2Clinical Epidemiology Department, Faculty of Medicine, Memorial University of Newfoundland, St.John's, NF, Canada, 3Medical Consultants of West Newfoundland, Western Memorial Hospital, Corner Brook, NF, Canada

    Background/Purpose: SLE is a chronic autoimmune disease with variable manifestations. New developments in the understanding and treatment of SLE mandated closer monitoring of the disease…
  • Abstract Number: 1356 • 2012 ACR/ARHP Annual Meeting

    Gender Differences Among Spondylitis Associated with Psoriasis, Inflammatory Bowel Disease and Primary Ankylosing Spondylitis

    Margarita Landi1, Hernan Maldonado-Ficco2, Jose A. Maldonado-Cocco2, Gustavo Citera3, Pablo Arturi2, Percival Sampaio-Barros4, Diana Flores5, Ruben Burgos-Vargas6, Helena Santos7, Jose Chavez-Corrales8, Daniel Palleiro9, Miguel A. Gutierrez10, Elsa Vieira-Sousa11, Fernando Pimentel-Santos12, Sergio O. Paira13, Alberto Berman Sr.14, Janitzia Vazquez-Mellado15, Eduardo Collantes-Estevez16 and On behalf of RESPONDIA Group17, 1Instituto de Rehabilitacion Psicofisica, Buenos Aires, Argentina, 2Rheumatology, Instituto de Rehabilitacion Psicofisica and Fundacion Reumatologica Argentina, Buenos Aires, Argentina, 3Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 4Rheumatology, University of Sao Paulo School of Medicine, Sao Paulo, Brazil, 5Rheumatology, Hospital Universitario, Monterrey, Mexico, 6Rheumatology, Hospital General de Mexico, Mexico DF, Mexico, 7Rheumatology, Instituto Português de Reumatologia, Lisboa, Portugal, 8Rheumatology, Hospital Nacional E. Rebagliti-ESSALUD, Lima, Peru, 9Rheumatology, Instituto Nacional de Reumatologia, Montevideo, Uruguay, 10Rheumatology and Inmunology, Pontificia Universidad Catolica de Chile, Santiago, Chile, 11Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal, 12Rheumatology, Centro Hospitalar de Lisboa Ocidental, Hospital Egas Moniz, Lisboa, Portugal, 13Hospital Jose María Cullen, Santa Fe SFE S3000BFP, Argentina, 14Internal Medicine, Hospital Padilla, Tucuman, Argentina, 15Rheumatology, Hospital General de Mexico, Mexico city, Mexico, 16Depatamento de Medicina, IMIBIC-Reina Sofia Hospital, Cordoba 14012, Spain, 17Buenos Aires

    Background/Purpose: Differences regarding gender in primary Ankylosing Spondylitis are well known. However, there is less evidence regarding Spondylitis Associated with Psoriasis and that associated with…
  • Abstract Number: 1357 • 2012 ACR/ARHP Annual Meeting

    Psoriatic Arthritis and Biologic Therapy: Treatment Response, Drug Survival and Outcome After Switching

    Dinny Wallis1, Deepak Jadon2, William Tillett2, Nicola Waldron2, Charlotte Cavill3, Neil McHugh4 and Eleanor Korendowych2, 1Rheumatology, Royal National Hospital for Rheumatic Diseases NHS Foundation Trust, Bath, United Kingdom, 2Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 3Rheumatology, Bath Institute for Rheumatic Disease, Bath, United Kingdom, 4Department of Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom

    Background/Purpose: Data on longer term efficacy and tolerance of biologic therapies in psoriatic arthritis (PsA) are emerging.  Persistence with the first TNF inhibitor (TNFi) at…
  • Abstract Number: 1358 • 2012 ACR/ARHP Annual Meeting

    Performance of Remission Criteria and Activity Indices in Psoriatic Arthritis

    Maria L. Acosta Felquer1, Leandro Ferreyra Garrott2, Erika Catay3, Josefina Marin4, Marina Scolnik5, Maria Victoria Garcia5, Santiago Ruta2, Mirtha Sabelli6, Zaida Bedran6, Javier Rosa3, Luis J. Catoggio7 and Enrique R. Soriano7, 1Internal Medicine, Rheumatology Section, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 2Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 3Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 4Internal Medicine, Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 5Internal Services, Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 6Rheumatology Section, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 7Internal Medicine, Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM. Catoggio, Buenos Aires, Argentina

    Background/Purpose: Remission criteria and activity indices used in rheumatoid arthritis (RA) are often applied in psoriatic arthritis (PsA). Although indices have been specifically developed for…
  • Abstract Number: 1359 • 2012 ACR/ARHP Annual Meeting

    Comparison of Sacroiliac MRI Evaluation Versus Sacroiliac x-Rays in Peripheral Psoriatic Arthritis: Evidence of Silent Disease and Lack of Association to HLA-B27

    Jose Luis Fernandez-Sueiro1, JA Pinto1, S. Pertega-Diaz2, E. Gonzalez3 and Francisco J. Blanco V4, 1Rheumatology Division, Complejo Hospitalario Universitario La Coruña, La Coruña, Spain, 2Epidemiology and Statistics, Complejo Hospitalario Universitario La Coruña, La Coruña, Spain, 3Rheumatology, Complejo Hospitalario Universitario La Coruña, La Coruña, Spain, 4Rheumatology Service, INIBIC-Hospital Universitario A Coruña, A Coruña, Spain

    Background/Purpose: Although there are no consensus on how to define spinal involvement in axial psoriatic artritis (axPsA), our data suggest that the presence of spinal…
  • Abstract Number: 1360 • 2012 ACR/ARHP Annual Meeting

    Spinal Involvement in Axial Psoriatic Artritis Is Not Determined by the Presence of HLA-B27. Is the HLA-B27 Arm of the Axial Spa Criteria Reliable for Classifying Axial Psoriatic Arthritis?

    Jose Luis Fernandez-Sueiro1, JA Pinto1, S. Pertega-Diaz2, E. Gonzalez3, Ignacio Rego-Perez4, Francisco J. de Toro-Santos5 and Francisco J. Blanco V6, 1Rheumatology Division, Complejo Hospitalario Universitario La Coruña, La Coruña, Spain, 2Epidemiology and Statistics, Complejo Hospitalario Universitario La Coruña, La Coruña, Spain, 3Rheumatology, Complejo Hospitalario Universitario La Coruña, La Coruña, Spain, 4INIBIC-Hospital Universitario A Coruña. Genomic Group. Rheumatology Division., A Coruña, Spain, 5Reumatology, Complejo Hospitalario Universitario Juan Canalejo, Universidad de la Coruña, La Coruña, Spain, 6Rheumatology Service, INIBIC-Hospital Universitario A Coruña, A Coruña, Spain

    Background/Purpose: There is a debate whether axial psoriatic arthritis (axPsA) is an ankylosing spondylitis with psoriasis, however due to the fact that PsA has characteristic…
  • Abstract Number: 1361 • 2012 ACR/ARHP Annual Meeting

    Disease Burden Is Comparable in Patients with Non-Radiographic Axial Spondyloarthritis and Ankylosing Spondylitis

    Joachim Sieper1, Désirée van der Heijde2, Dirk Elewaut3, Aileen L. Pangan4 and Jaclyn K. Anderson4, 1Rheumatology, Charité Universitätesmedizin Berlin, Berlin, Germany, 2Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Rheumatology, Department of Rheumatology Ghent University Hospital, Ghent, Belgium, 4Abbott Laboratories, Abbott Park, IL

    Background/Purpose: Chronic back pain and functional impairment are disease characteristics common to all patients (pts) with axial spondyloarthritis (SpA), regardless of the presence of radiographic…
  • Abstract Number: 1362 • 2012 ACR/ARHP Annual Meeting

    Evaluation of Spondyloarthritis activity  by the Patients and the Physicians: ASDAS, Basdai, PASS and Flare

    Marie Godfrin-Valnet1, Clément Prati2, Marc Puyraveau3, Eric Toussirot4, Helene Letho-Gyselinck5 and Daniel Wendling5, 1Rheumatology, CHU, Besançon, France, 2Service de Rhumatologie, CHU J Minjoz, Besancon, France, 3Clinical Methodology Center, CHU, Besançon, France, 4Université de Franche Comté , CHRU, CIC Biotherapy 506 and Rheumatology and EA 4266 Pathogens and Inflammation, Besançon, France, 5Service de Rhumatologie, Minjoz University Hospital, Besancon, France

    Background/Purpose: Objectives: to define thresholds of the ASDAS corresponding to the PASS (Pateint Acceptable Symptomatic State) and to the thresholds of activity of the disease…
  • Abstract Number: 1363 • 2012 ACR/ARHP Annual Meeting

    Validation of the Self-Administered Comorbidity Questionnaire in Patients with Ankylosing Spondylitis

    Carmen Stolwijk1, A.M. Van Tubergen2, Sofia Ramiro3, Ivette Essers1, Marc Blaauw1, Désirée van der Heijde4, Robert B. M. Landewé5, Filip Van den Bosch6, Maxime Dougados7 and Annelies Boonen8, 1Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, 2Department of Medicine, Maastricht University Medical Center, Maastricht, Netherlands, 3Clinical Immunology & Rheumatology, Academic Medical Center, University of Amsterdam, The Netherlands and Hospital Garcia de Orta, Almada, Portugal, 4Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 5Academic Medical Center/University of Amsterdam & Atrium Medical Center, Amsterdam, Netherlands, 6Rheumatology, Ghent University Hospital, Ghent, Belgium, 7Rheumatology B Department, Paris-Descartes University, APHP, Cochin Hospital, Paris, France, 8Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands

    Background/Purpose: Comorbidities can importantly influence the results of clinical studies on functional outcomes as they may act as confounders or effect modifiers. The generic self-administered…
  • Abstract Number: 1364 • 2012 ACR/ARHP Annual Meeting

    Development, Sensibility and Reliability of a New Case-Finding Questionnaire, the Toronto Axial Spondyloarthritis Questionnaire in Inflammatory Bowel Disease

    Khalid A. Alnaqbi1, Zahi Touma1, Laura A. Passalent2, Sindhu R. Johnson1, George A. Tomlinson3, Adele Carty1 and Robert D. Inman1, 1Rheumatology, Toronto Western Hospital, Toronto, ON, Canada, 2Allied Health, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, 3Dept of Medicine/Rheumatology, Toronto General Hospital, Toronto, ON, Canada

    Background/Purpose: Inflammatory bowel disease (IBD) encompasses Crohn's disease, ulcerative colitis, and indeterminate colitis. Articular involvement [(peripheral arthritis and axial spondyloarthritis (axSpA)] is the most common…
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